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The map label for this gene is cysQ [H]

Identifier: 85375560

GI number: 85375560

Start: 2753627

End: 2754394

Strand: Reverse

Name: cysQ [H]

Synonym: ELI_13665

Alternate gene names: 85375560

Gene position: 2754394-2753627 (Counterclockwise)

Preceding gene: 85375561

Following gene: 85375551

Centisome position: 90.24

GC content: 68.62

Gene sequence:

>768_bases
GTGACCGGCATGACGGAAAACCTATCGACCGAGCTGAGCGACGGAGAGTTTGCCGCGCGCCTGGCGCAGCAAGCGGGCGC
AATCCTGCTCGATATCCGTGCTGCGGGCGAACTCGCAGGCAAGGCGCTGGGCCAGGCAGGCGACGAGGCGGCCAATGCCT
TTATCTGCAATGCGATCCGGACGTATCGCCCTGACGACGCCTTGCTTTCCGAAGAAGAGAAGGACAACCCGGCCCGCTGC
GATCGCTCGCGCGTGTGGATTGTCGATCCCGTCGACGGCACGCGCGAATATGGCGAAGCACGCAGCGACTGGGCGGTCCA
TGTCGGGTTGGCGGTCGACGGCGCGGCGAGCCTCGGCGCGGTGGCCCTGCCCGGCCTCGACGGCGGCGTGGTGCTCCGTT
CGGACGAACCACGGAGTCTGCCCGCAGCGCCGGATCGGCCCCGCATGGTGGTGAGCCGGACGCGACCGGCCGCCGAGGCG
GTCGCGGTCGCGGAACTGCTAGGCGCGGAACTGGTGCCGATGGGATCGGCGGGCGCCAAGGCCATGGCGGTGGTGCGCGG
CGAGGCGGAAATCTACCTGCATTCGGGCGGGCAATACGAATGGGACAATTGCGCGCCGGTAGCCGTGGCGGAAGCGCACG
GCCTGTTCTGTTCGCGCATCGACGGTTCGCCGCTGCACTACAACCGGCGCGATCCCTATCTGCCCGATCTGCTGATCTGC
CGCCCGGAATGGACCGGGCGGGTATTTGCGGCGCTGGGCAAGCCCTAG

Upstream 100 bases:

>100_bases
CCTACGAGCCTCCCGAAAACGCAGAGATTCGCGTCAACACGGTGGAAATGACGCCCGAGGAAGCCGCCGACCATATCATC
GCCGCGATCCTGCCGCTCAA

Downstream 100 bases:

>100_bases
TCTACCGGCGCTGCCGACGGCGTCGCCTGGGGTGTCGGCGTCGCTTCGACCATCATGCCTTCGGGCACATCGACGCGGAT
TTCGACGCGGCGGTTGGCGG

Product: putative inositol monophosphatase

Products: NA

Alternate protein names: PAP phosphatase; 3'(2'),5'-bisphosphate nucleotidase; 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; D-fructose-1,6-bisphosphate 1-phosphohydrolase; DPNPase; Fructose-1,6-bisphosphatase; FBPase; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTGMTENLSTELSDGEFAARLAQQAGAILLDIRAAGELAGKALGQAGDEAANAFICNAIRTYRPDDALLSEEEKDNPARC
DRSRVWIVDPVDGTREYGEARSDWAVHVGLAVDGAASLGAVALPGLDGGVVLRSDEPRSLPAAPDRPRMVVSRTRPAAEA
VAVAELLGAELVPMGSAGAKAMAVVRGEAEIYLHSGGQYEWDNCAPVAVAEAHGLFCSRIDGSPLHYNRRDPYLPDLLIC
RPEWTGRVFAALGKP

Sequences:

>Translated_255_residues
MTGMTENLSTELSDGEFAARLAQQAGAILLDIRAAGELAGKALGQAGDEAANAFICNAIRTYRPDDALLSEEEKDNPARC
DRSRVWIVDPVDGTREYGEARSDWAVHVGLAVDGAASLGAVALPGLDGGVVLRSDEPRSLPAAPDRPRMVVSRTRPAAEA
VAVAELLGAELVPMGSAGAKAMAVVRGEAEIYLHSGGQYEWDNCAPVAVAEAHGLFCSRIDGSPLHYNRRDPYLPDLLIC
RPEWTGRVFAALGKP
>Mature_254_residues
TGMTENLSTELSDGEFAARLAQQAGAILLDIRAAGELAGKALGQAGDEAANAFICNAIRTYRPDDALLSEEEKDNPARCD
RSRVWIVDPVDGTREYGEARSDWAVHVGLAVDGAASLGAVALPGLDGGVVLRSDEPRSLPAAPDRPRMVVSRTRPAAEAV
AVAELLGAELVPMGSAGAKAMAVVRGEAEIYLHSGGQYEWDNCAPVAVAEAHGLFCSRIDGSPLHYNRRDPYLPDLLICR
PEWTGRVFAALGKP

Specific function: Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can ser

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Localized On The Inner Face Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=210, Percent_Identity=30, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71995897, Length=228, Percent_Identity=27.6315789473684, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71995905, Length=228, Percent_Identity=27.6315789473684, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7; =3.1.3.11; =3.1.3.25 [H]

Molecular weight: Translated: 26989; Mature: 26857

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGMTENLSTELSDGEFAARLAQQAGAILLDIRAAGELAGKALGQAGDEAANAFICNAIR
CCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
TYRPDDALLSEEEKDNPARCDRSRVWIVDPVDGTREYGEARSDWAVHVGLAVDGAASLGA
HCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCEEEEEEEEECCCCCCCE
VALPGLDGGVVLRSDEPRSLPAAPDRPRMVVSRTRPAAEAVAVAELLGAELVPMGSAGAK
EECCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEECCCCCCCE
AMAVVRGEAEIYLHSGGQYEWDNCAPVAVAEAHGLFCSRIDGSPLHYNRRDPYLPDLLIC
EEEEEECCEEEEEECCCCCCCCCCCCEEEEHHCCEEEECCCCCCCCCCCCCCCCCCEEEE
RPEWTGRVFAALGKP
CCCCCCEEEEECCCC
>Mature Secondary Structure 
TGMTENLSTELSDGEFAARLAQQAGAILLDIRAAGELAGKALGQAGDEAANAFICNAIR
CCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
TYRPDDALLSEEEKDNPARCDRSRVWIVDPVDGTREYGEARSDWAVHVGLAVDGAASLGA
HCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCEEEEEEEEECCCCCCCE
VALPGLDGGVVLRSDEPRSLPAAPDRPRMVVSRTRPAAEAVAVAELLGAELVPMGSAGAK
EECCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEECCCCCCCE
AMAVVRGEAEIYLHSGGQYEWDNCAPVAVAEAHGLFCSRIDGSPLHYNRRDPYLPDLLIC
EEEEEECCEEEEEECCCCCCCCCCCCEEEEHHCCEEEECCCCCCCCCCCCCCCCCCEEEE
RPEWTGRVFAALGKP
CCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]