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The map label for this gene is coq7 [H]

Identifier: 85375478

GI number: 85375478

Start: 2669024

End: 2669545

Strand: Direct

Name: coq7 [H]

Synonym: ELI_13255

Alternate gene names: 85375478

Gene position: 2669024-2669545 (Clockwise)

Preceding gene: 85375477

Following gene: 85375479

Centisome position: 87.44

GC content: 66.09

Gene sequence:

>522_bases
ATGAGCAAGCCCGATATCGCCCGCATGATCCGCGTCGACCAGGCCGGGGAATTCGGGGCAACCCGAATTTACGAAGGCCA
GCTCGCGGTGATGGGCAATCGCGGACCGCATTCGGGCGAGATTGCCGCTATGGCGCAACAGGAAGAGGGGCATCGCGAAA
AGTTCGATGCGCTGATGGCCCGGCGCGGCGTCAGGCCGACCGCTCTGCAGCCGTTCTGGTCCTTCGCCGGCTACGCACTG
GGCGCAGGAACCGCCCTGCTTGGCCCCGAGGCGGCGATGGCCTGCACCGCGGCGGTCGAGACCGAGATCGACAAGCATTA
TTCCGACCAGCTCGATGCGCTGGAAGAGAGCGGCGACGACCCCGAATTGGCGGAGATGATCCGCGAGTTTCGTGAAGACG
AGCGCGAACACCGTGACGCGGCGCTGGAAATGGGGGCCGAGAGGGCGCCCGCCTATCCGGTCCTTTCCGGCCTGATCCGG
CTCGGCTGCCGCGCGGCGATCAAGGTTAGCGAACGTGTCTGA

Upstream 100 bases:

>100_bases
TGGCAGGCTGGAACTTTGTCATCTCGACCCTCGTTGGTCTGGTGATCCTGTTCCTCCTCGCGAGGAACGACACTGAAGCA
GACCAGGGAATCGCCGCCGC

Downstream 100 bases:

>100_bases
CCTGCATCGCTGCTTTGCGCGTGCCCCACGCTTCATATAGAGTTCACCGCCTGGCGGCGATGGTGCTGCCAACGCTTTCC
TACCGACGGACCAGCCCCAT

Product: ubiquinone biosynthesis protein

Products: NA

Alternate protein names: 5-demethoxyubiquinone hydroxylase; DMQ hydroxylase [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSKPDIARMIRVDQAGEFGATRIYEGQLAVMGNRGPHSGEIAAMAQQEEGHREKFDALMARRGVRPTALQPFWSFAGYAL
GAGTALLGPEAAMACTAAVETEIDKHYSDQLDALEESGDDPELAEMIREFREDEREHRDAALEMGAERAPAYPVLSGLIR
LGCRAAIKVSERV

Sequences:

>Translated_173_residues
MSKPDIARMIRVDQAGEFGATRIYEGQLAVMGNRGPHSGEIAAMAQQEEGHREKFDALMARRGVRPTALQPFWSFAGYAL
GAGTALLGPEAAMACTAAVETEIDKHYSDQLDALEESGDDPELAEMIREFREDEREHRDAALEMGAERAPAYPVLSGLIR
LGCRAAIKVSERV
>Mature_172_residues
SKPDIARMIRVDQAGEFGATRIYEGQLAVMGNRGPHSGEIAAMAQQEEGHREKFDALMARRGVRPTALQPFWSFAGYALG
AGTALLGPEAAMACTAAVETEIDKHYSDQLDALEESGDDPELAEMIREFREDEREHRDAALEMGAERAPAYPVLSGLIRL
GCRAAIKVSERV

Specific function: Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol [H]

COG id: COG2941

COG function: function code H; Ubiquinone biosynthesis protein COQ7

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COQ7 family [H]

Homologues:

Organism=Homo sapiens, GI300244542, Length=177, Percent_Identity=51.4124293785311, Blast_Score=174, Evalue=5e-44,
Organism=Homo sapiens, GI25453484, Length=177, Percent_Identity=51.4124293785311, Blast_Score=172, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17552756, Length=173, Percent_Identity=44.5086705202312, Blast_Score=139, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6324699, Length=180, Percent_Identity=42.7777777777778, Blast_Score=139, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24640215, Length=166, Percent_Identity=49.3975903614458, Blast_Score=172, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012347
- InterPro:   IPR009078
- InterPro:   IPR011566 [H]

Pfam domain/function: PF03232 COQ7 [H]

EC number: NA

Molecular weight: Translated: 18891; Mature: 18759

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPDIARMIRVDQAGEFGATRIYEGQLAVMGNRGPHSGEIAAMAQQEEGHREKFDALMA
CCCCHHHHHHHHHCCCCCCCCEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRGVRPTALQPFWSFAGYALGAGTALLGPEAAMACTAAVETEIDKHYSDQLDALEESGDD
HCCCCCCHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PELAEMIREFREDEREHRDAALEMGAERAPAYPVLSGLIRLGCRAAIKVSERV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKPDIARMIRVDQAGEFGATRIYEGQLAVMGNRGPHSGEIAAMAQQEEGHREKFDALMA
CCCHHHHHHHHHCCCCCCCCEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRGVRPTALQPFWSFAGYALGAGTALLGPEAAMACTAAVETEIDKHYSDQLDALEESGDD
HCCCCCCHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PELAEMIREFREDEREHRDAALEMGAERAPAYPVLSGLIRLGCRAAIKVSERV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]