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The map label for this gene is ywlC [H]

Identifier: 85375447

GI number: 85375447

Start: 2638067

End: 2639011

Strand: Direct

Name: ywlC [H]

Synonym: ELI_13100

Alternate gene names: 85375447

Gene position: 2638067-2639011 (Clockwise)

Preceding gene: 85375444

Following gene: 85375455

Centisome position: 86.43

GC content: 68.36

Gene sequence:

>945_bases
ATGCGCGACAAGAACGCTACGGAAGTGCTGCGGGGCGACCGCCATGGCGTGGCGCAGGCTGCACGTATCATCAACGCGGG
CGGCCTAGTCGCCGTTCCGACCGAAACCGTTTACGGCCTCGCCGCACGCGCGGACGATCCGGACGCGGTGGCCGCCATCT
ATGCTGCCAAGGGGCGCCCCAGTTTCAATCCGTTGATCGTGCACGTCCTCGATCCGGCAGCTGCCGGTCGGCTGGTCGAG
ATGGACGACAAGGCGCAGGCTCTGGCGGGGCGCTTTTGGCCCGGGCCGTTAACGATGGTCCTGCCGCTTCGCGATGCTGC
GGATGTTGCCGGCGCCGTGACGGCAGGCCTGCCCACGCTCGCCGTTCGTGTACCGGCGCACCCGCTCATGCGCGAGCTAC
TGACTCTGGCCGAAGCGCCGCTTGCCGCGCCATCCGCCAATGTCAGCGAAAGCGTCAGCCCGACATCGCCTGGCCATGTC
CTGAAGACGCTGGACGGCCGGATCGACGCCGTGCTCGACGGGGGCGAATGCATTGCCGGATTGGAATCCACGATCGTCGC
TCTGCGCGGCGATGGTGCGTGGTCTTTGCTGCGACCCGGACCGATTGCCAAAGAAGCCTTGATCGAGGCGCTCGGTGCCG
AGCCCTCCGGCACAACGGAGGGCGTCGAGGCGCCCGGTCAATTGGCGCGGCACTACTCGCCGGGCAAGCCCGTGAGACTG
GGCGCTGTCGAGGCTGCCGAGGACGAATTCCTCCTCGGCTTCGGAAACACCGCAGGAGACTGGTCGCTATCCGACAGCGG
CGATCCGGCCGAAGCAGCGGCGCGACTTTACGCGGGCCTGCATCGCGGGGCGGAGAGCGACAAAGCGCGGATTGCCGTCG
CGCCGATCCCCGACGAAGGGCTGGGCGCAGCCATCAACGACCGGCTCCGCCGCGCCGCAGCCTGA

Upstream 100 bases:

>100_bases
CGCGGATCGATAGCAATTGGTCCTGAGTGGCGGGCGTATAGGGTGTCACGGCGCGGAAAGTCCTCTTGGCTTAGCTGGGT
ATCAGATATAGCGCTCGGGG

Downstream 100 bases:

>100_bases
TTATTCGTCGGGTTCGACCGGTACACTCGGGAGCAGATCGCGAATCTCGTCATAAGTTGCGCGCGCATCGGCGCAGGCCT
CGCGATCGCCTTCGGCGCAC

Product: putative translation factor

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MRDKNATEVLRGDRHGVAQAARIINAGGLVAVPTETVYGLAARADDPDAVAAIYAAKGRPSFNPLIVHVLDPAAAGRLVE
MDDKAQALAGRFWPGPLTMVLPLRDAADVAGAVTAGLPTLAVRVPAHPLMRELLTLAEAPLAAPSANVSESVSPTSPGHV
LKTLDGRIDAVLDGGECIAGLESTIVALRGDGAWSLLRPGPIAKEALIEALGAEPSGTTEGVEAPGQLARHYSPGKPVRL
GAVEAAEDEFLLGFGNTAGDWSLSDSGDPAEAAARLYAGLHRGAESDKARIAVAPIPDEGLGAAINDRLRRAAA

Sequences:

>Translated_314_residues
MRDKNATEVLRGDRHGVAQAARIINAGGLVAVPTETVYGLAARADDPDAVAAIYAAKGRPSFNPLIVHVLDPAAAGRLVE
MDDKAQALAGRFWPGPLTMVLPLRDAADVAGAVTAGLPTLAVRVPAHPLMRELLTLAEAPLAAPSANVSESVSPTSPGHV
LKTLDGRIDAVLDGGECIAGLESTIVALRGDGAWSLLRPGPIAKEALIEALGAEPSGTTEGVEAPGQLARHYSPGKPVRL
GAVEAAEDEFLLGFGNTAGDWSLSDSGDPAEAAARLYAGLHRGAESDKARIAVAPIPDEGLGAAINDRLRRAAA
>Mature_314_residues
MRDKNATEVLRGDRHGVAQAARIINAGGLVAVPTETVYGLAARADDPDAVAAIYAAKGRPSFNPLIVHVLDPAAAGRLVE
MDDKAQALAGRFWPGPLTMVLPLRDAADVAGAVTAGLPTLAVRVPAHPLMRELLTLAEAPLAAPSANVSESVSPTSPGHV
LKTLDGRIDAVLDGGECIAGLESTIVALRGDGAWSLLRPGPIAKEALIEALGAEPSGTTEGVEAPGQLARHYSPGKPVRL
GAVEAAEDEFLLGFGNTAGDWSLSDSGDPAEAAARLYAGLHRGAESDKARIAVAPIPDEGLGAAINDRLRRAAA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=200, Percent_Identity=32.5, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=193, Percent_Identity=35.2331606217617, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321269, Length=375, Percent_Identity=34.4, Blast_Score=154, Evalue=1e-38,
Organism=Drosophila melanogaster, GI78707274, Length=208, Percent_Identity=29.8076923076923, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 32152; Mature: 32152

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDKNATEVLRGDRHGVAQAARIINAGGLVAVPTETVYGLAARADDPDAVAAIYAAKGRP
CCCCCHHHHHCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCHHEEEEEEECCCC
SFNPLIVHVLDPAAAGRLVEMDDKAQALAGRFWPGPLTMVLPLRDAADVAGAVTAGLPTL
CCCCEEEEEECCCCCCCEEECCCHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCEE
AVRVPAHPLMRELLTLAEAPLAAPSANVSESVSPTSPGHVLKTLDGRIDAVLDGGECIAG
EEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHC
LESTIVALRGDGAWSLLRPGPIAKEALIEALGAEPSGTTEGVEAPGQLARHYSPGKPVRL
CCCEEEEEECCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCEEE
GAVEAAEDEFLLGFGNTAGDWSLSDSGDPAEAAARLYAGLHRGAESDKARIAVAPIPDEG
EEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
LGAAINDRLRRAAA
CCHHHHHHHHHHCC
>Mature Secondary Structure
MRDKNATEVLRGDRHGVAQAARIINAGGLVAVPTETVYGLAARADDPDAVAAIYAAKGRP
CCCCCHHHHHCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCHHEEEEEEECCCC
SFNPLIVHVLDPAAAGRLVEMDDKAQALAGRFWPGPLTMVLPLRDAADVAGAVTAGLPTL
CCCCEEEEEECCCCCCCEEECCCHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCEE
AVRVPAHPLMRELLTLAEAPLAAPSANVSESVSPTSPGHVLKTLDGRIDAVLDGGECIAG
EEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHC
LESTIVALRGDGAWSLLRPGPIAKEALIEALGAEPSGTTEGVEAPGQLARHYSPGKPVRL
CCCEEEEEECCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCEEE
GAVEAAEDEFLLGFGNTAGDWSLSDSGDPAEAAARLYAGLHRGAESDKARIAVAPIPDEG
EEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
LGAAINDRLRRAAA
CCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]