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The map label for this gene is 85375444

Identifier: 85375444

GI number: 85375444

Start: 2633959

End: 2635440

Strand: Direct

Name: 85375444

Synonym: ELI_13085

Alternate gene names: NA

Gene position: 2633959-2635440 (Clockwise)

Preceding gene: 85375441

Following gene: 85375447

Centisome position: 86.29

GC content: 65.99

Gene sequence:

>1482_bases
ATGAGCACCTTCCGCAAAATCCTTATCGCCCTGCTGGTCTTTTTCATCGTCCTCGGTCTGCTGGGGTTCTGGCTGACCAG
GGGCGACACTGCCGATCTTTCCGTCGAGGCGGTCAGCGGCACCGATCCGACGCTGGCGGAAGCCGAGGAAGAAGCCTTCC
CGACCGTGCAGATCGCCAAGCCTGTCGGTTGGGCAGAAGGCGAAGTGCCGACAGCGGCCGAGGGCCTCGAAGTGGTGCGC
TTTGCCGAGGGTCTCGATCATCCGCGCGTGCTCCATCGCCTGCCGAACGGCGATGTCCTCGTCACGCTGACCCGCGCGCC
GAAGGGCGATGGCGGAGGAGATGGCGGCATCATGGCGAGCATCCGCAATTTCGTCGCCGGCCTGCTGTTCGAACGGGCAG
GGGCCGCGGGCGAATCGCCCAACGAGCTGGTGCTGCTGCGCGACGCGGATGGCGACGGGGTGGCCGAGATCAGGCAGACG
CTCACCGACGACCTCGATTCGCCCTCGGGCATCGCGTGGTCCGACGGAACGCTTTATATCGCCAATCACGATGCGGTCCT
CGCGTTCCCTTACGAGCTCGGCGCCTCCACGCTGACTGGCGACCCGCGCAAGCTGATGGACCTGCCGCCGGGCGGCGGGC
ACTGGATGCGCAATATCGAGCTCAATCCGGATGGCACCAAACTCTACATCGCGGTCGGTTCGGTCTCGAATATCGGCGAG
CAGGGTATGGAGGTCGAACAGGGCCGGGCCATGATCTGGGAATACGATCTCGAGACCGACACCCCGCGCCAGTTCGCGCT
CGGCCTGCGCAATCCCAACGGGCTCGACTGGAACCCGATGTCCGGTGAGCTGTGGACCACCGTCAACGAGCGCGACATGC
TGGGCTCGGATCTGGTGCCGGACTACCTGACCAATGTTCCCGTCGGCGCGCAGTACGGCTGGCCCTGGGTATACTGGAAG
GACAATATCGACACCCGCGTCGATGCGCCGCGTCCTGCCTTTCTCGTCGAATATACCCGCCGTCCGGAATACGCGATGGG
GCCGCACGTGGCGGCGTTGGGACTAGTCTTTACGGCGGACGGTCACCGCGTGGGCGAAGCTTTCTCGCGCGGTGCCTTCG
TGGCACGGCACGGCTCATGGAACCGCAAGCCGCCTTCGGGTTACGACGTCGTCTATGTCGCTTTCGACGAGCGCGGCAAT
CCGCAGGGCAAGCCGATCCCGGTGCTGACCGACTTCCTCAAAGAAGACGGCACTACGCGCGGCCGCCCGACCTGGGTCGA
ATGGGCCGGCGATGGCTCGCTGCTGGTGAGCGACGACACCGCAGGCATTATTTGGCGCGTGGTGGCACCGGGCGCCGAGC
CGGGCACGGCACCGGCGCGCTTCCGCAGCGAGAGCCTGCGGCCCCAGACCGAACTCCGTGGCGATCCGCGCGCGAGCTTC
GGCGAGGACTTCGCGCGCGAAAGCAATCCGAACGTCAACTAG

Upstream 100 bases:

>100_bases
TCGAACATGCAGGGTGATTTAGCCGCTCGCACCCGCCACACAAGCGCCCGGGCGAGCAAAATCGTTGCCGCGCTGTGATA
GCGTGACTATCTCCTGTTGC

Downstream 100 bases:

>100_bases
GTACTAAAGGGATTTTCCGGCACGCCCGGCCAGTTCGGTGACGAACTGCCGAGCCGTGCGCCCCGACCGCGCACCGCGCT
GGCGCGCCCATGTGAGCGCG

Product: L-sorbosone dehydrogenase

Products: NA

Alternate protein names: SNDH [H]

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MSTFRKILIALLVFFIVLGLLGFWLTRGDTADLSVEAVSGTDPTLAEAEEEAFPTVQIAKPVGWAEGEVPTAAEGLEVVR
FAEGLDHPRVLHRLPNGDVLVTLTRAPKGDGGGDGGIMASIRNFVAGLLFERAGAAGESPNELVLLRDADGDGVAEIRQT
LTDDLDSPSGIAWSDGTLYIANHDAVLAFPYELGASTLTGDPRKLMDLPPGGGHWMRNIELNPDGTKLYIAVGSVSNIGE
QGMEVEQGRAMIWEYDLETDTPRQFALGLRNPNGLDWNPMSGELWTTVNERDMLGSDLVPDYLTNVPVGAQYGWPWVYWK
DNIDTRVDAPRPAFLVEYTRRPEYAMGPHVAALGLVFTADGHRVGEAFSRGAFVARHGSWNRKPPSGYDVVYVAFDERGN
PQGKPIPVLTDFLKEDGTTRGRPTWVEWAGDGSLLVSDDTAGIIWRVVAPGAEPGTAPARFRSESLRPQTELRGDPRASF
GEDFARESNPNVN

Sequences:

>Translated_493_residues
MSTFRKILIALLVFFIVLGLLGFWLTRGDTADLSVEAVSGTDPTLAEAEEEAFPTVQIAKPVGWAEGEVPTAAEGLEVVR
FAEGLDHPRVLHRLPNGDVLVTLTRAPKGDGGGDGGIMASIRNFVAGLLFERAGAAGESPNELVLLRDADGDGVAEIRQT
LTDDLDSPSGIAWSDGTLYIANHDAVLAFPYELGASTLTGDPRKLMDLPPGGGHWMRNIELNPDGTKLYIAVGSVSNIGE
QGMEVEQGRAMIWEYDLETDTPRQFALGLRNPNGLDWNPMSGELWTTVNERDMLGSDLVPDYLTNVPVGAQYGWPWVYWK
DNIDTRVDAPRPAFLVEYTRRPEYAMGPHVAALGLVFTADGHRVGEAFSRGAFVARHGSWNRKPPSGYDVVYVAFDERGN
PQGKPIPVLTDFLKEDGTTRGRPTWVEWAGDGSLLVSDDTAGIIWRVVAPGAEPGTAPARFRSESLRPQTELRGDPRASF
GEDFARESNPNVN
>Mature_492_residues
STFRKILIALLVFFIVLGLLGFWLTRGDTADLSVEAVSGTDPTLAEAEEEAFPTVQIAKPVGWAEGEVPTAAEGLEVVRF
AEGLDHPRVLHRLPNGDVLVTLTRAPKGDGGGDGGIMASIRNFVAGLLFERAGAAGESPNELVLLRDADGDGVAEIRQTL
TDDLDSPSGIAWSDGTLYIANHDAVLAFPYELGASTLTGDPRKLMDLPPGGGHWMRNIELNPDGTKLYIAVGSVSNIGEQ
GMEVEQGRAMIWEYDLETDTPRQFALGLRNPNGLDWNPMSGELWTTVNERDMLGSDLVPDYLTNVPVGAQYGWPWVYWKD
NIDTRVDAPRPAFLVEYTRRPEYAMGPHVAALGLVFTADGHRVGEAFSRGAFVARHGSWNRKPPSGYDVVYVAFDERGNP
QGKPIPVLTDFLKEDGTTRGRPTWVEWAGDGSLLVSDDTAGIIWRVVAPGAEPGTAPARFRSESLRPQTELRGDPRASFG
EDFARESNPNVN

Specific function: Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA) [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.burgdorferi BB024 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 53567; Mature: 53435

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFRKILIALLVFFIVLGLLGFWLTRGDTADLSVEAVSGTDPTLAEAEEEAFPTVQIAK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCEEEEEC
PVGWAEGEVPTAAEGLEVVRFAEGLDHPRVLHRLPNGDVLVTLTRAPKGDGGGDGGIMAS
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHH
IRNFVAGLLFERAGAAGESPNELVLLRDADGDGVAEIRQTLTDDLDSPSGIAWSDGTLYI
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEECCCEEEE
ANHDAVLAFPYELGASTLTGDPRKLMDLPPGGGHWMRNIELNPDGTKLYIAVGSVSNIGE
ECCCEEEEEEHHHCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCEEEEEECCCHHHHH
QGMEVEQGRAMIWEYDLETDTPRQFALGLRNPNGLDWNPMSGELWTTVNERDMLGSDLVP
CCCEECCCCEEEEEEECCCCCCHHHEEECCCCCCCCCCCCCCCEEEECCHHHCCCCCCCH
DYLTNVPVGAQYGWPWVYWKDNIDTRVDAPRPAFLVEYTRRPEYAMGPHVAALGLVFTAD
HHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECC
GHRVGEAFSRGAFVARHGSWNRKPPSGYDVVYVAFDERGNPQGKPIPVLTDFLKEDGTTR
CCHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCC
GRPTWVEWAGDGSLLVSDDTAGIIWRVVAPGAEPGTAPARFRSESLRPQTELRGDPRASF
CCCCEEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCHHHHHHCCCCHHHCCCCCCCCH
GEDFARESNPNVN
HHHHHHCCCCCCC
>Mature Secondary Structure 
STFRKILIALLVFFIVLGLLGFWLTRGDTADLSVEAVSGTDPTLAEAEEEAFPTVQIAK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCEEEEEC
PVGWAEGEVPTAAEGLEVVRFAEGLDHPRVLHRLPNGDVLVTLTRAPKGDGGGDGGIMAS
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHH
IRNFVAGLLFERAGAAGESPNELVLLRDADGDGVAEIRQTLTDDLDSPSGIAWSDGTLYI
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEECCCEEEE
ANHDAVLAFPYELGASTLTGDPRKLMDLPPGGGHWMRNIELNPDGTKLYIAVGSVSNIGE
ECCCEEEEEEHHHCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCEEEEEECCCHHHHH
QGMEVEQGRAMIWEYDLETDTPRQFALGLRNPNGLDWNPMSGELWTTVNERDMLGSDLVP
CCCEECCCCEEEEEEECCCCCCHHHEEECCCCCCCCCCCCCCCEEEECCHHHCCCCCCCH
DYLTNVPVGAQYGWPWVYWKDNIDTRVDAPRPAFLVEYTRRPEYAMGPHVAALGLVFTAD
HHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECC
GHRVGEAFSRGAFVARHGSWNRKPPSGYDVVYVAFDERGNPQGKPIPVLTDFLKEDGTTR
CCHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCC
GRPTWVEWAGDGSLLVSDDTAGIIWRVVAPGAEPGTAPARFRSESLRPQTELRGDPRASF
CCCCEEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCHHHHHHCCCCHHHCCCCCCCCH
GEDFARESNPNVN
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7574579 [H]