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The map label for this gene is yfhR [C]

Identifier: 85375330

GI number: 85375330

Start: 2531940

End: 2532761

Strand: Reverse

Name: yfhR [C]

Synonym: ELI_12515

Alternate gene names: 85375330

Gene position: 2532761-2531940 (Counterclockwise)

Preceding gene: 85375331

Following gene: 85375328

Centisome position: 82.98

GC content: 64.6

Gene sequence:

>822_bases
TTGCGAACCCTGCTGACGGTGCTGGCCATCGTGGCGGGGATTTATCTCGCCATCGCTCTGGCGGCCTGGGCAGCGCAGGG
ACAGCTCATCTATCCCGCCCTGCGTGGCCAGTCTGTGCCCGAAGAAAGCTATGAAGTCGTCGCGTTGCCGACCGCTGACG
GTTTGGAGCTGCGCGTTTTCTGGCGTGAGGGTGAGCCTGGCAAGCCGGTGGTGCTGTATTTCCATGGCAATGGCGGCACC
TTGGCGGGCAGTACGCAGGCGACCCGCGCCTTGGTCGCGGCCGGGTTCAGCGTCCTGTTGCCGGCCTATCGAGGTTACGA
GGACAATGAGGGCACGCCGCACGAAAAGGGCCTCTACACTGACGGGCGTGCGGCGCTCGCCTGGCTGGCTGACAAAGGCG
TCGCGCCCGAAAATCTCGTCGTCATCGGCAATTCGATCGGTACCGGGCCGGCAATGCAGATGGCGTCGGAGGTCGATCCG
CTCGCGCTGATCCTTATCTCACCCTTCACCAGCTTGCCCGAGATTGCCGCGTCGAAGATGCCGATCCTGCCGATGCCGCT
CTTGCTGCGCGACCGCTACGACAATTCCGCCAAGATCGGTTCGCTCGACATGCCAATCCTGATACAGGCCGGCAGCGCCG
ATACGCTTATCCCCGCGACGCACGGGCGGGCCCTGGCGCGGCTTGCGCCGGATGCAGACTTGCAGATCTTCGATGGCCTC
GGGCACGATCTCAATTTTCGCCCGGAAACGGACGCGGCGCGGGTGCGCTGGCTGGAAGCCGAGGTTTTGCAACCTACTGC
CCCGGCGACCCCGTCGGAATGA

Upstream 100 bases:

>100_bases
AGGCCGGCCTCACTGCGCCGCACATCGTCGACACCGTGCTCAAGGCGCTGCGCCAAAACAGCGCCGGCGTCGAAGAGGCG
CGGGCCTGACCCTCGCGGAG

Downstream 100 bases:

>100_bases
CCGTGGCTTGAGCGACCGCCACCAGTTTGGGCTCGGCATCGTCGCCCTCGCTCCACACATCGGCGCGCACGATCACCTGC
TTGCGGCCCGCCTTCATCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MRTLLTVLAIVAGIYLAIALAAWAAQGQLIYPALRGQSVPEESYEVVALPTADGLELRVFWREGEPGKPVVLYFHGNGGT
LAGSTQATRALVAAGFSVLLPAYRGYEDNEGTPHEKGLYTDGRAALAWLADKGVAPENLVVIGNSIGTGPAMQMASEVDP
LALILISPFTSLPEIAASKMPILPMPLLLRDRYDNSAKIGSLDMPILIQAGSADTLIPATHGRALARLAPDADLQIFDGL
GHDLNFRPETDAARVRWLEAEVLQPTAPATPSE

Sequences:

>Translated_273_residues
MRTLLTVLAIVAGIYLAIALAAWAAQGQLIYPALRGQSVPEESYEVVALPTADGLELRVFWREGEPGKPVVLYFHGNGGT
LAGSTQATRALVAAGFSVLLPAYRGYEDNEGTPHEKGLYTDGRAALAWLADKGVAPENLVVIGNSIGTGPAMQMASEVDP
LALILISPFTSLPEIAASKMPILPMPLLLRDRYDNSAKIGSLDMPILIQAGSADTLIPATHGRALARLAPDADLQIFDGL
GHDLNFRPETDAARVRWLEAEVLQPTAPATPSE
>Mature_273_residues
MRTLLTVLAIVAGIYLAIALAAWAAQGQLIYPALRGQSVPEESYEVVALPTADGLELRVFWREGEPGKPVVLYFHGNGGT
LAGSTQATRALVAAGFSVLLPAYRGYEDNEGTPHEKGLYTDGRAALAWLADKGVAPENLVVIGNSIGTGPAMQMASEVDP
LALILISPFTSLPEIAASKMPILPMPLLLRDRYDNSAKIGSLDMPILIQAGSADTLIPATHGRALARLAPDADLQIFDGL
GHDLNFRPETDAARVRWLEAEVLQPTAPATPSE

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=215, Percent_Identity=30.2325581395349, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI109689718, Length=209, Percent_Identity=30.622009569378, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI24308097, Length=209, Percent_Identity=30.622009569378, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI71051600, Length=215, Percent_Identity=30.6976744186047, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI71051602, Length=215, Percent_Identity=30.6976744186047, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI194306564, Length=209, Percent_Identity=29.6650717703349, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI32451492, Length=188, Percent_Identity=30.3191489361702, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI32528310, Length=188, Percent_Identity=30.3191489361702, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI194306562, Length=182, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI151301175, Length=191, Percent_Identity=30.3664921465969, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI226510965, Length=238, Percent_Identity=27.7310924369748, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17566318, Length=209, Percent_Identity=31.1004784688995, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71988362, Length=213, Percent_Identity=31.4553990610329, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532877, Length=201, Percent_Identity=32.8358208955224, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25143554, Length=146, Percent_Identity=29.4520547945205, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324009, Length=231, Percent_Identity=27.7056277056277, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17137566, Length=241, Percent_Identity=31.1203319502075, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 28970; Mature: 28970

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLLTVLAIVAGIYLAIALAAWAAQGQLIYPALRGQSVPEESYEVVALPTADGLELRVF
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEEE
WREGEPGKPVVLYFHGNGGTLAGSTQATRALVAAGFSVLLPAYRGYEDNEGTPHEKGLYT
EECCCCCCCEEEEEECCCCEECCCHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCC
DGRAALAWLADKGVAPENLVVIGNSIGTGPAMQMASEVDPLALILISPFTSLPEIAASKM
CCHHEEEEHHHCCCCCCCEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHCCC
PILPMPLLLRDRYDNSAKIGSLDMPILIQAGSADTLIPATHGRALARLAPDADLQIFDGL
CCCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCEEECCCCCCCEEEECCC
GHDLNFRPETDAARVRWLEAEVLQPTAPATPSE
CCCCCCCCCCCHHHEEEEHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRTLLTVLAIVAGIYLAIALAAWAAQGQLIYPALRGQSVPEESYEVVALPTADGLELRVF
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEEE
WREGEPGKPVVLYFHGNGGTLAGSTQATRALVAAGFSVLLPAYRGYEDNEGTPHEKGLYT
EECCCCCCCEEEEEECCCCEECCCHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCC
DGRAALAWLADKGVAPENLVVIGNSIGTGPAMQMASEVDPLALILISPFTSLPEIAASKM
CCHHEEEEHHHCCCCCCCEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHCCC
PILPMPLLLRDRYDNSAKIGSLDMPILIQAGSADTLIPATHGRALARLAPDADLQIFDGL
CCCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCEEECCCCCCCEEEECCC
GHDLNFRPETDAARVRWLEAEVLQPTAPATPSE
CCCCCCCCCCCHHHEEEEHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]