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The map label for this gene is yclF [H]

Identifier: 85375324

GI number: 85375324

Start: 2525960

End: 2527531

Strand: Direct

Name: yclF [H]

Synonym: ELI_12485

Alternate gene names: 85375324

Gene position: 2525960-2527531 (Clockwise)

Preceding gene: 85375317

Following gene: 85375325

Centisome position: 82.75

GC content: 63.36

Gene sequence:

>1572_bases
ATGGCAACGCAATCCATGCCGCATGGGGATTCCGCGGGGACGATCCTGGGTCATCCCAAGGGGCTATTCGTCCTGTTCTT
CGCCGAAATGTGGGAGCGCTTCTCCTACTACGGCATGCGGGCGCTGCTGATTTTCTACCTGACCAAGCACTGGCTGTTTT
CGGACAGCGAGAGCGGCATCATCTACGGTGCCTACACCGCGCTGGTCTACATCACCCCGGTGGTCGGCGGGTACATGGCC
GATAAATATCTCGGACAGAGGAAGGCGGTCGCCTTCGGGGCCGTCTTGCTGACGCTGGGTCACTTTTTCATGGCGTTCGA
GGGCGCTCCGGCTGCGGGCAATGTCGATAATCCCGTCATCTATGTGTTCTGGCTCGCGCTCGCGCTGATCATCGTCGGCT
CGGGCTTTCTGAAGGCCAACATTTCGGTGATCGTCGGCCAGCTCTATCCGCGCACCGATGTGCGCCGCGACGGGGCCTAT
ACGATCTTCTACATGGGCATTAACCTCGGCGCCGCGATCGGTTCGCTGCTGTGCGGCTATATCGGGGAAACCTATGGCTG
GGCCTACGGTTTCGGGCTGGCCGGCATCGGCATGCTGCTGGGCCTGATCGTCTTTACCTGGGGCAAGCCGCTGCTGCTCG
GCAGGGGCGAGCCGCCCAAGCCGCTGGCCAAGAGCACCGAATGGACGATGTACGGCATCGGGTTCGTGCTTGTCGCAATC
TGCTGGGCGCTGATCCAGTACCAGTCGGTGGTCGGCTGGCTCCTCGGCGGGTTCGGCCTGGTGCTCGTTTCCTATGTCAT
CGGTACTGCGGTGACCAAGCTGGAGCCGGACGATCGCGACCGCATCTTTGCGGCCCTGTTCCTGATCCTGACCTCGATCA
TCTTCTGGGCGTTGTTCGAGCAGGCGGGCTCTTCGCTCAACCTGTTCACCGATCGGCACGTGGACCGCGGCGGCGTGCCC
GCCTCGACCTTCCAGTCGATCAACGCGATCTACATCATCCTGCTCGCCCCGGTGTTCGCCACAGCGTGGACGTGGCTGGG
CCGCAAGGGGATGGAGCCGTCCTCGCCCTTCAAGTTCGGGCTTGGCGTCATCCAGGTCGGGCTTGGCTTCCTGGTGCTGG
TCTGGGGTGCCAATTCGGTCGGCATCGACGTGCCGACGCCGGTGATCTTCATCTTCCTGATCTACCTGTTGCACACCACC
GGTGAGCTGTGCCTCAGCCCGGTCGGCCTGTCGGCCATGAACCGGCTGGCCCCGGCCCATATGGCATCGCTCATCATGGG
CACCTGGTTCTTCGCATCGGCCACCGGCAATTTCGCCGCCGGCCTGATCGCGGCGGCGACGGGTGCCGAAGGCGTCGGCG
AAGAAGCCGGCAAGCAGGTCGTGCTGGATGTCTATTCGACCGTCGGCTGGGTCGCCGTCGGTGTCGGCATCGGCGTGCTG
GTCATCAGCCCCTTCGTCAAGAAGCTGATGCATCTCGACACGCTCAAGGACGACGAACTGGAGGGCGCTGCCGAAGCAGG
TTACGAACCGCAGGAAGCGGGCGTCCATCCGACCACGCGTCCGGCTCGGTAA

Upstream 100 bases:

>100_bases
ATCTTCACATCGGCAAAACAGCCGCTAGGGTGCGCCGTTTGAAAAGGGCCGGGGGAGATGCGGCCCGTATTCGGGTTCAA
AACGAGAGGCTTTTCGCACA

Downstream 100 bases:

>100_bases
TCTCATCCTCGTAAAGTCACCAAGGGGGTCATCACTATGCGTCTAGCTGCGCTTCTCGCTTGCGGAGGCGCACTGGCGCT
GGCCGCCTGTTCCGCCACGA

Product: di-tripeptide ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 522

Protein sequence:

>523_residues
MATQSMPHGDSAGTILGHPKGLFVLFFAEMWERFSYYGMRALLIFYLTKHWLFSDSESGIIYGAYTALVYITPVVGGYMA
DKYLGQRKAVAFGAVLLTLGHFFMAFEGAPAAGNVDNPVIYVFWLALALIIVGSGFLKANISVIVGQLYPRTDVRRDGAY
TIFYMGINLGAAIGSLLCGYIGETYGWAYGFGLAGIGMLLGLIVFTWGKPLLLGRGEPPKPLAKSTEWTMYGIGFVLVAI
CWALIQYQSVVGWLLGGFGLVLVSYVIGTAVTKLEPDDRDRIFAALFLILTSIIFWALFEQAGSSLNLFTDRHVDRGGVP
ASTFQSINAIYIILLAPVFATAWTWLGRKGMEPSSPFKFGLGVIQVGLGFLVLVWGANSVGIDVPTPVIFIFLIYLLHTT
GELCLSPVGLSAMNRLAPAHMASLIMGTWFFASATGNFAAGLIAAATGAEGVGEEAGKQVVLDVYSTVGWVAVGVGIGVL
VISPFVKKLMHLDTLKDDELEGAAEAGYEPQEAGVHPTTRPAR

Sequences:

>Translated_523_residues
MATQSMPHGDSAGTILGHPKGLFVLFFAEMWERFSYYGMRALLIFYLTKHWLFSDSESGIIYGAYTALVYITPVVGGYMA
DKYLGQRKAVAFGAVLLTLGHFFMAFEGAPAAGNVDNPVIYVFWLALALIIVGSGFLKANISVIVGQLYPRTDVRRDGAY
TIFYMGINLGAAIGSLLCGYIGETYGWAYGFGLAGIGMLLGLIVFTWGKPLLLGRGEPPKPLAKSTEWTMYGIGFVLVAI
CWALIQYQSVVGWLLGGFGLVLVSYVIGTAVTKLEPDDRDRIFAALFLILTSIIFWALFEQAGSSLNLFTDRHVDRGGVP
ASTFQSINAIYIILLAPVFATAWTWLGRKGMEPSSPFKFGLGVIQVGLGFLVLVWGANSVGIDVPTPVIFIFLIYLLHTT
GELCLSPVGLSAMNRLAPAHMASLIMGTWFFASATGNFAAGLIAAATGAEGVGEEAGKQVVLDVYSTVGWVAVGVGIGVL
VISPFVKKLMHLDTLKDDELEGAAEAGYEPQEAGVHPTTRPAR
>Mature_522_residues
ATQSMPHGDSAGTILGHPKGLFVLFFAEMWERFSYYGMRALLIFYLTKHWLFSDSESGIIYGAYTALVYITPVVGGYMAD
KYLGQRKAVAFGAVLLTLGHFFMAFEGAPAAGNVDNPVIYVFWLALALIIVGSGFLKANISVIVGQLYPRTDVRRDGAYT
IFYMGINLGAAIGSLLCGYIGETYGWAYGFGLAGIGMLLGLIVFTWGKPLLLGRGEPPKPLAKSTEWTMYGIGFVLVAIC
WALIQYQSVVGWLLGGFGLVLVSYVIGTAVTKLEPDDRDRIFAALFLILTSIIFWALFEQAGSSLNLFTDRHVDRGGVPA
STFQSINAIYIILLAPVFATAWTWLGRKGMEPSSPFKFGLGVIQVGLGFLVLVWGANSVGIDVPTPVIFIFLIYLLHTTG
ELCLSPVGLSAMNRLAPAHMASLIMGTWFFASATGNFAAGLIAAATGAEGVGEEAGKQVVLDVYSTVGWVAVGVGIGVLV
ISPFVKKLMHLDTLKDDELEGAAEAGYEPQEAGVHPTTRPAR

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=436, Percent_Identity=25.2293577981651, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI226371746, Length=363, Percent_Identity=25.6198347107438, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI1789911, Length=488, Percent_Identity=30.5327868852459, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1790572, Length=443, Percent_Identity=32.0541760722348, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1786927, Length=468, Percent_Identity=32.2649572649573, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1787922, Length=475, Percent_Identity=29.2631578947368, Blast_Score=211, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17569141, Length=391, Percent_Identity=24.8081841432225, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17541704, Length=309, Percent_Identity=26.8608414239482, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71987453, Length=366, Percent_Identity=24.5901639344262, Blast_Score=92, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6322946, Length=474, Percent_Identity=22.7848101265823, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28571098, Length=350, Percent_Identity=28, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI28571102, Length=350, Percent_Identity=28, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571100, Length=350, Percent_Identity=28, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24639585, Length=340, Percent_Identity=26.7647058823529, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24639583, Length=340, Percent_Identity=26.7647058823529, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639581, Length=340, Percent_Identity=26.7647058823529, Blast_Score=104, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 56202; Mature: 56071

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50850 MFS ; PS01022 PTR2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQSMPHGDSAGTILGHPKGLFVLFFAEMWERFSYYGMRALLIFYLTKHWLFSDSESGI
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
IYGAYTALVYITPVVGGYMADKYLGQRKAVAFGAVLLTLGHFFMAFEGAPAAGNVDNPVI
EEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
YVFWLALALIIVGSGFLKANISVIVGQLYPRTDVRRDGAYTIFYMGINLGAAIGSLLCGY
HHHHHHHHHHHHCCCHHHCCHHHHEECCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHH
IGETYGWAYGFGLAGIGMLLGLIVFTWGKPLLLGRGEPPKPLAKSTEWTMYGIGFVLVAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
CWALIQYQSVVGWLLGGFGLVLVSYVIGTAVTKLEPDDRDRIFAALFLILTSIIFWALFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QAGSSLNLFTDRHVDRGGVPASTFQSINAIYIILLAPVFATAWTWLGRKGMEPSSPFKFG
HHCCCEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LGVIQVGLGFLVLVWGANSVGIDVPTPVIFIFLIYLLHTTGELCLSPVGLSAMNRLAPAH
HHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHH
MASLIMGTWFFASATGNFAAGLIAAATGAEGVGEEAGKQVVLDVYSTVGWVAVGVGIGVL
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VISPFVKKLMHLDTLKDDELEGAAEAGYEPQEAGVHPTTRPAR
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
ATQSMPHGDSAGTILGHPKGLFVLFFAEMWERFSYYGMRALLIFYLTKHWLFSDSESGI
CCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
IYGAYTALVYITPVVGGYMADKYLGQRKAVAFGAVLLTLGHFFMAFEGAPAAGNVDNPVI
EEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
YVFWLALALIIVGSGFLKANISVIVGQLYPRTDVRRDGAYTIFYMGINLGAAIGSLLCGY
HHHHHHHHHHHHCCCHHHCCHHHHEECCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHH
IGETYGWAYGFGLAGIGMLLGLIVFTWGKPLLLGRGEPPKPLAKSTEWTMYGIGFVLVAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
CWALIQYQSVVGWLLGGFGLVLVSYVIGTAVTKLEPDDRDRIFAALFLILTSIIFWALFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QAGSSLNLFTDRHVDRGGVPASTFQSINAIYIILLAPVFATAWTWLGRKGMEPSSPFKFG
HHCCCEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LGVIQVGLGFLVLVWGANSVGIDVPTPVIFIFLIYLLHTTGELCLSPVGLSAMNRLAPAH
HHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHH
MASLIMGTWFFASATGNFAAGLIAAATGAEGVGEEAGKQVVLDVYSTVGWVAVGVGIGVL
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VISPFVKKLMHLDTLKDDELEGAAEAGYEPQEAGVHPTTRPAR
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]