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The map label for this gene is linC [H]

Identifier: 85375316

GI number: 85375316

Start: 2518001

End: 2519338

Strand: Direct

Name: linC [H]

Synonym: ELI_12445

Alternate gene names: 85375316

Gene position: 2518001-2519338 (Clockwise)

Preceding gene: 85375315

Following gene: 85375317

Centisome position: 82.49

GC content: 62.71

Gene sequence:

>1338_bases
ATGGCCACGATCGCCCCCCAGCGGCCCGAATGCCGCAGCGAACCGACCGCCTACGAAGCGCTCAAGAAGCATTTCGAAGA
GCACCCCGAAGAGCGTCCGCAGCATACGCACAAATGGGACGTCAGCCGCAGCGATATCTACTACGAGAACACCTGGCATC
CGATCTTCCGCGAAATGCGCGAGGCCGGCCCCCTGCATTATATTCCCGAAAGCCCCTTCGGCCCGTACTGGGCAGTCGTC
GGCCACAAGGCGATCCAGCATATCGAAGCGCTGCCGGACGTATTCTCCTCCAGCTGGGAACATGGCGGCATCACCATCCT
CAACCGCCTGAGCGACGAAGAGCGTGAAGAGAGCGGTGTCGACCGCCGCGAATTGCCGATGTTCATCGCCATGGACCGGC
CCGAGCATACCGGCCAGCGCCGCACCGTCGCGCCAAAATTCACCCCCAGCGGCATGGCCGAGATGGAAGGCGAAATCCGC
CAGCGCACCGGCGAATTGCTCGATTCCCTGCCGCGCGGCGAAGTCTTCGACTGGGTCGACAAAGTCTCCATCGAACTCAC
CACCGGCATGCTCGCGATCCTGTTCGGTTTCCCGTGGGAAGACCGCCGCCTGCTGACCTTCTGGTCCGACTGGTCGGGCG
ATACCGAGCTCGCCACCGTGCGCGAACTCGACGAGATGCGCTGGGGCTTCCTCCACGAGATGGCGGCCTATTTCCAGTCG
CTGTGGGTCGAGCGCACGCATGACAAGGAACCGGGCGACGATCTCATCTCGATGATGATCCATTCGCCCGCGATGAACCA
GATGCGCCCGGAAGAATTCATGGGCAACCTCGTGCTGCTGATCGTCGGCGGGAACGACACCACCCGCAATTCGATGAGCG
GGATCATCTACCAGCTCGACAAGAACCCCGACCAGCGCAAGCTGTTCGAGCAACAGCCCGAGCTGATCCCCAACGCCGTG
CAGGAAATCCTGCGCATGCAGACCCCGCTCGCACACATGCGCCGGACCTGCACCGAAGACACCGAAGTGTTCGGCCAGAA
GATCAAGAAAGGCGACAAGGTCGTCCTCTGGTATCTCAGCGCCAACCGCGACGAGGAAGTCTTCGAAAACCCGGACAAGC
TCGACATCACGCGCGAGAATGCCCGCCGCCATATCGCCTTCGGGTACGGCATCCACCGCTGCGTCGGTGCGCGGTTGGCC
GAACTGCAGCTGCGCGTGCTGCTGGAAGAGCTGCACAAGCGCCGCATGCGGGTGCATCTGGCGGGCGATGTCGAGCGGGT
GCGCGCCAATTTCGTGCACGGCTTCCGCAAGCTGGAAGTCGAGGTCACCGAATTCTGA

Upstream 100 bases:

>100_bases
GCAAAACGCAACTCACTATTGACACGCCTGTCAATAACAGCAGGATGGGCGGCAATGACGGACGGCCTGAATGAGTCGTC
CGCACAAGGAGAGAGACCCG

Downstream 100 bases:

>100_bases
GGTGAAACCTTTCCGCGCTCCGCAGCGTATTCAGAGATGAGACATTCCCTCTACGCTACGGAGCACCACATGACCAAAGA
TCCAAATCGCCGCCAGATGC

Product: cytochrome P450 family protein

Products: NA

Alternate protein names: Cytochrome P450 111; Cytochrome P450lin [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MATIAPQRPECRSEPTAYEALKKHFEEHPEERPQHTHKWDVSRSDIYYENTWHPIFREMREAGPLHYIPESPFGPYWAVV
GHKAIQHIEALPDVFSSSWEHGGITILNRLSDEEREESGVDRRELPMFIAMDRPEHTGQRRTVAPKFTPSGMAEMEGEIR
QRTGELLDSLPRGEVFDWVDKVSIELTTGMLAILFGFPWEDRRLLTFWSDWSGDTELATVRELDEMRWGFLHEMAAYFQS
LWVERTHDKEPGDDLISMMIHSPAMNQMRPEEFMGNLVLLIVGGNDTTRNSMSGIIYQLDKNPDQRKLFEQQPELIPNAV
QEILRMQTPLAHMRRTCTEDTEVFGQKIKKGDKVVLWYLSANRDEEVFENPDKLDITRENARRHIAFGYGIHRCVGARLA
ELQLRVLLEELHKRRMRVHLAGDVERVRANFVHGFRKLEVEVTEF

Sequences:

>Translated_445_residues
MATIAPQRPECRSEPTAYEALKKHFEEHPEERPQHTHKWDVSRSDIYYENTWHPIFREMREAGPLHYIPESPFGPYWAVV
GHKAIQHIEALPDVFSSSWEHGGITILNRLSDEEREESGVDRRELPMFIAMDRPEHTGQRRTVAPKFTPSGMAEMEGEIR
QRTGELLDSLPRGEVFDWVDKVSIELTTGMLAILFGFPWEDRRLLTFWSDWSGDTELATVRELDEMRWGFLHEMAAYFQS
LWVERTHDKEPGDDLISMMIHSPAMNQMRPEEFMGNLVLLIVGGNDTTRNSMSGIIYQLDKNPDQRKLFEQQPELIPNAV
QEILRMQTPLAHMRRTCTEDTEVFGQKIKKGDKVVLWYLSANRDEEVFENPDKLDITRENARRHIAFGYGIHRCVGARLA
ELQLRVLLEELHKRRMRVHLAGDVERVRANFVHGFRKLEVEVTEF
>Mature_444_residues
ATIAPQRPECRSEPTAYEALKKHFEEHPEERPQHTHKWDVSRSDIYYENTWHPIFREMREAGPLHYIPESPFGPYWAVVG
HKAIQHIEALPDVFSSSWEHGGITILNRLSDEEREESGVDRRELPMFIAMDRPEHTGQRRTVAPKFTPSGMAEMEGEIRQ
RTGELLDSLPRGEVFDWVDKVSIELTTGMLAILFGFPWEDRRLLTFWSDWSGDTELATVRELDEMRWGFLHEMAAYFQSL
WVERTHDKEPGDDLISMMIHSPAMNQMRPEEFMGNLVLLIVGGNDTTRNSMSGIIYQLDKNPDQRKLFEQQPELIPNAVQ
EILRMQTPLAHMRRTCTEDTEVFGQKIKKGDKVVLWYLSANRDEEVFENPDKLDITRENARRHIAFGYGIHRCVGARLAE
LQLRVLLEELHKRRMRVHLAGDVERVRANFVHGFRKLEVEVTEF

Specific function: Catalyzes the 8-methyl hydroxylation of linalool [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI4503211, Length=305, Percent_Identity=24.5901639344262, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: =1.14.99.28 [H]

Molecular weight: Translated: 51971; Mature: 51839

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIAPQRPECRSEPTAYEALKKHFEEHPEERPQHTHKWDVSRSDIYYENTWHPIFREMR
CCCCCCCCCCCCCCCHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHH
EAGPLHYIPESPFGPYWAVVGHKAIQHIEALPDVFSSSWEHGGITILNRLSDEEREESGV
HCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHCC
DRRELPMFIAMDRPEHTGQRRTVAPKFTPSGMAEMEGEIRQRTGELLDSLPRGEVFDWVD
CHHHCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KVSIELTTGMLAILFGFPWEDRRLLTFWSDWSGDTELATVRELDEMRWGFLHEMAAYFQS
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LWVERTHDKEPGDDLISMMIHSPAMNQMRPEEFMGNLVLLIVGGNDTTRNSMSGIIYQLD
HHHHHCCCCCCHHHHHHHHHHCCHHHCCCHHHHCCCEEEEEECCCCCCCHHHCCEEEEEC
KNPDQRKLFEQQPELIPNAVQEILRMQTPLAHMRRTCTEDTEVFGQKIKKGDKVVLWYLS
CCCCHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEE
ANRDEEVFENPDKLDITRENARRHIAFGYGIHRCVGARLAELQLRVLLEELHKRRMRVHL
CCCCHHHHCCCCCEEEEHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHC
AGDVERVRANFVHGFRKLEVEVTEF
CCCHHHHHHHHHHHHHHEEEEEECC
>Mature Secondary Structure 
ATIAPQRPECRSEPTAYEALKKHFEEHPEERPQHTHKWDVSRSDIYYENTWHPIFREMR
CCCCCCCCCCCCCCHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHH
EAGPLHYIPESPFGPYWAVVGHKAIQHIEALPDVFSSSWEHGGITILNRLSDEEREESGV
HCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHCC
DRRELPMFIAMDRPEHTGQRRTVAPKFTPSGMAEMEGEIRQRTGELLDSLPRGEVFDWVD
CHHHCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KVSIELTTGMLAILFGFPWEDRRLLTFWSDWSGDTELATVRELDEMRWGFLHEMAAYFQS
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LWVERTHDKEPGDDLISMMIHSPAMNQMRPEEFMGNLVLLIVGGNDTTRNSMSGIIYQLD
HHHHHCCCCCCHHHHHHHHHHCCHHHCCCHHHHCCCEEEEEECCCCCCCHHHCCEEEEEC
KNPDQRKLFEQQPELIPNAVQEILRMQTPLAHMRRTCTEDTEVFGQKIKKGDKVVLWYLS
CCCCHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEE
ANRDEEVFENPDKLDITRENARRHIAFGYGIHRCVGARLAELQLRVLLEELHKRRMRVHL
CCCCHHHHCCCCCEEEEHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHC
AGDVERVRANFVHGFRKLEVEVTEF
CCCHHHHHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8376348; 2295633; 3813557; 2578028; 1610873; 12237225 [H]