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The map label for this gene is cirA [C]

Identifier: 85375128

GI number: 85375128

Start: 2325185

End: 2327371

Strand: Reverse

Name: cirA [C]

Synonym: ELI_11505

Alternate gene names: 85375128

Gene position: 2327371-2325185 (Counterclockwise)

Preceding gene: 85375131

Following gene: 85375124

Centisome position: 76.25

GC content: 64.79

Gene sequence:

>2187_bases
ATGACATCGAACGCTTCCCCCCTGCGTTCCGCCGTTTCCGCCATCGCTCTGGCTAGCGCTTTCGCGGCCGCCCCGCTCGC
GGCGCAAGACGAGACGGACGACGATCAGCGCGCAAGCCAGCAGGCAGACGACGACTTTCACAACCGTTCGCGCGATCTCC
CGCCCGAGATCGTGGTGACGGCTGCCGGATTGACCCAGCTCGATGTGCTGGCCGGAACCTCGGTGCTGGAAGGGTTCGAA
CTGCAGCGCTCGCTCGACGGTACGCTCGGTGACACCTTGGTCAAGATCCCCGGCGTCTCCTCGACCGGCTTCGCGCCCGG
TTCTTCCCGACCAGTGCTGCGCGGCCTCCAGGGCGAGCGCGTGCGCGTCCTGATCGACGGGCTCGGCGCGATCGATGTCT
CCAACACCTCGGTCGACCACGCCGTGACGATCGATGTACTGACCGCCGAGCGCATCGATATCCTGCGCGGCCCCGCCGTT
CTGCTGTACGGCAGCTCGGCGATCGGCGGCGCGGTGAACGTCATCGACAAGCGCATTCCGCGGCGCATACCGGACGAGAA
AATCCACATCGATGGCCTGGTGCGCGGCGACACCGCGCTCGATACGCGGGAATTCGGCGCGTCCCTCGATGCTCCGCTCG
GATCGATGTTCGTGTTCCACGTCGATGGCTCCTATCGCAACACCAACGACCTCGAGATCGCCGGCTTCCAGATCGCGCCG
GACCTGCGTGCGGACCTGCTGGCCGATGCGGATGAGGAGGAGGAAGAAGGCGAATTCGAGGAAGCGGACGAGATGCGCGA
GGCCGCCAACCAGACCGGCTTCGTCCCCAATTCGGCCACCGAAACCTGGACTGCCAATGCCGGCCTGACTTTTTTTTCGG
GCGATAGCAATCTCGGCTTTGCCGTCGGCTGGTACGACACCCGTTACGGCGTGCCCGGCAACCCCGAGGGCGGCCATCAT
CACGGCGAAGGGGAGGAAGGCGAAGAGGAAGAAGGCGAGGGCGGGGAAGGGGGCGAAGAGATCGTCAGCATCGACCTGCG
GCAGTTTCGCGCCGATCTTCGCGGCGAGCTCGACCTCGGCGACGGCTTCTTCGACACCCTGATCACCCGCGCCGGCTTCA
GCGATTACACCCACACCGAATTCGAAGGCGACGAGGTCGGTACGGTTTTCGACGTGCAGGGCTTCGAAGCCCGCGCCGAG
CTCGCCCAGACCCGCCGCAACGGCTGGGGCGGCAACACCGGCGTGCAATTCTACCTGCGCGACTTCGTTGCTTTCGGCGC
CGAGGCCTACGTGCCGAAGAACACCACGACGCAGTTCGCGGTCTTCACCTTGCAGGAATTCGATCTCGGCGGGGTCCAGC
TCGAGGTTGCGGGGCGGTACGAAACGACCGATATCGAGTCGACCACCGTCGGAATCGAGCGGAAGTTCGACACGTTCTCC
GGGGCGCTCAGCCTGTCGCGCGAGACCGAGAGCGGCTTGCGCTTCGGCGTCAATGTCAGCCGTGCCGAACGTGCGCCGAG
TGCGGAAGAGCTGCTTTCCAACGGGCCGCACATTGCCACGCAGGCCTTCGAAATCGGCGACCCCGACCTCTCGGTCGAAA
GCGCCTGGGGCGTCGAGGCTTACCTTCGGGGACGCATCGGTCCGGCGACGATCAGCCTCGCCGCCTATCGCAACTGGTTC
GACGACTTCATCTACTTGCAGGACACCGGTCTTGAGGAGGACGAACTTCCCGTCTTCGTCTATCTCCAGCAGGGCGCGAC
TTACACCGGCTTCGAAGGCGAGATCGAATTCCCGTTGATCGATAGCGGGCCGTTCCGCCTGACGACCGACCTTCATGTCG
AATATGTCGATGCCGACCTCGACGACGGCAGCTCCGTCCCGCGCACCCCGCCGCTAAGCCTGCTCGGCGCGCTCGAGGCG
GACTGGGAACAGTTCAACATCCGCGGCGAAGTCCAGTGGTTCGACGACCAGGACAGCGTGAGCGCGTTCGAAACGCCGAC
CGATGGGTTTACCTTCGTCAATGCTTCGATCGCTTGGCGACCGATCCGCGGCGACAACAACGTGACCCTGCTGCTTCAGG
CCGAGAACATCTTCGATGTCACCGGCCGCCGCCACGCCAGCTTCACCAAGGACTTCGTCCCGCTCGCAGGGCGCAACATC
AAGGGCAGCGTGCGCTTCAGCTTCTGA

Upstream 100 bases:

>100_bases
GAGCGCGGCGAATAATGTTATTCTGTATCATCCGGTTCCGCGCTGGTCCAGTTCCGCTGCGCTAACGGCCCGGTGATCGC
AACCAAGAGGTCCTTACACG

Downstream 100 bases:

>100_bases
GCGCGCGCTCCCCGTCGCGTTCTAGTCGTGTCGTGCCGTGGCGGCGGTTTCCGCCCCCTTGGCACGGCCTTCGGCGTGGG
CGGCCTTGATTTCGGCCTTC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 728; Mature: 727

Protein sequence:

>728_residues
MTSNASPLRSAVSAIALASAFAAAPLAAQDETDDDQRASQQADDDFHNRSRDLPPEIVVTAAGLTQLDVLAGTSVLEGFE
LQRSLDGTLGDTLVKIPGVSSTGFAPGSSRPVLRGLQGERVRVLIDGLGAIDVSNTSVDHAVTIDVLTAERIDILRGPAV
LLYGSSAIGGAVNVIDKRIPRRIPDEKIHIDGLVRGDTALDTREFGASLDAPLGSMFVFHVDGSYRNTNDLEIAGFQIAP
DLRADLLADADEEEEEGEFEEADEMREAANQTGFVPNSATETWTANAGLTFFSGDSNLGFAVGWYDTRYGVPGNPEGGHH
HGEGEEGEEEEGEGGEGGEEIVSIDLRQFRADLRGELDLGDGFFDTLITRAGFSDYTHTEFEGDEVGTVFDVQGFEARAE
LAQTRRNGWGGNTGVQFYLRDFVAFGAEAYVPKNTTTQFAVFTLQEFDLGGVQLEVAGRYETTDIESTTVGIERKFDTFS
GALSLSRETESGLRFGVNVSRAERAPSAEELLSNGPHIATQAFEIGDPDLSVESAWGVEAYLRGRIGPATISLAAYRNWF
DDFIYLQDTGLEEDELPVFVYLQQGATYTGFEGEIEFPLIDSGPFRLTTDLHVEYVDADLDDGSSVPRTPPLSLLGALEA
DWEQFNIRGEVQWFDDQDSVSAFETPTDGFTFVNASIAWRPIRGDNNVTLLLQAENIFDVTGRRHASFTKDFVPLAGRNI
KGSVRFSF

Sequences:

>Translated_728_residues
MTSNASPLRSAVSAIALASAFAAAPLAAQDETDDDQRASQQADDDFHNRSRDLPPEIVVTAAGLTQLDVLAGTSVLEGFE
LQRSLDGTLGDTLVKIPGVSSTGFAPGSSRPVLRGLQGERVRVLIDGLGAIDVSNTSVDHAVTIDVLTAERIDILRGPAV
LLYGSSAIGGAVNVIDKRIPRRIPDEKIHIDGLVRGDTALDTREFGASLDAPLGSMFVFHVDGSYRNTNDLEIAGFQIAP
DLRADLLADADEEEEEGEFEEADEMREAANQTGFVPNSATETWTANAGLTFFSGDSNLGFAVGWYDTRYGVPGNPEGGHH
HGEGEEGEEEEGEGGEGGEEIVSIDLRQFRADLRGELDLGDGFFDTLITRAGFSDYTHTEFEGDEVGTVFDVQGFEARAE
LAQTRRNGWGGNTGVQFYLRDFVAFGAEAYVPKNTTTQFAVFTLQEFDLGGVQLEVAGRYETTDIESTTVGIERKFDTFS
GALSLSRETESGLRFGVNVSRAERAPSAEELLSNGPHIATQAFEIGDPDLSVESAWGVEAYLRGRIGPATISLAAYRNWF
DDFIYLQDTGLEEDELPVFVYLQQGATYTGFEGEIEFPLIDSGPFRLTTDLHVEYVDADLDDGSSVPRTPPLSLLGALEA
DWEQFNIRGEVQWFDDQDSVSAFETPTDGFTFVNASIAWRPIRGDNNVTLLLQAENIFDVTGRRHASFTKDFVPLAGRNI
KGSVRFSF
>Mature_727_residues
TSNASPLRSAVSAIALASAFAAAPLAAQDETDDDQRASQQADDDFHNRSRDLPPEIVVTAAGLTQLDVLAGTSVLEGFEL
QRSLDGTLGDTLVKIPGVSSTGFAPGSSRPVLRGLQGERVRVLIDGLGAIDVSNTSVDHAVTIDVLTAERIDILRGPAVL
LYGSSAIGGAVNVIDKRIPRRIPDEKIHIDGLVRGDTALDTREFGASLDAPLGSMFVFHVDGSYRNTNDLEIAGFQIAPD
LRADLLADADEEEEEGEFEEADEMREAANQTGFVPNSATETWTANAGLTFFSGDSNLGFAVGWYDTRYGVPGNPEGGHHH
GEGEEGEEEEGEGGEGGEEIVSIDLRQFRADLRGELDLGDGFFDTLITRAGFSDYTHTEFEGDEVGTVFDVQGFEARAEL
AQTRRNGWGGNTGVQFYLRDFVAFGAEAYVPKNTTTQFAVFTLQEFDLGGVQLEVAGRYETTDIESTTVGIERKFDTFSG
ALSLSRETESGLRFGVNVSRAERAPSAEELLSNGPHIATQAFEIGDPDLSVESAWGVEAYLRGRIGPATISLAAYRNWFD
DFIYLQDTGLEEDELPVFVYLQQGATYTGFEGEIEFPLIDSGPFRLTTDLHVEYVDADLDDGSSVPRTPPLSLLGALEAD
WEQFNIRGEVQWFDDQDSVSAFETPTDGFTFVNASIAWRPIRGDNNVTLLLQAENIFDVTGRRHASFTKDFVPLAGRNIK
GSVRFSF

Specific function: Probable receptor, tonB-dependent [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=132, Percent_Identity=35.6060606060606, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 78969; Mature: 78838

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNASPLRSAVSAIALASAFAAAPLAAQDETDDDQRASQQADDDFHNRSRDLPPEIVVT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHHCCCCCCCCEEEE
AAGLTQLDVLAGTSVLEGFELQRSLDGTLGDTLVKIPGVSSTGFAPGSSRPVLRGLQGER
ECCCCEEHHHHCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCE
VRVLIDGLGAIDVSNTSVDHAVTIDVLTAERIDILRGPAVLLYGSSAIGGAVNVIDKRIP
EEEEEECCCEEEECCCCCCCEEEEEEEEHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCC
RRIPDEKIHIDGLVRGDTALDTREFGASLDAPLGSMFVFHVDGSYRNTNDLEIAGFQIAP
CCCCCCEEEEEEEEECCCCCCHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECC
DLRADLLADADEEEEEGEFEEADEMREAANQTGFVPNSATETWTANAGLTFFSGDSNLGF
CHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEECCCCCCE
AVGWYDTRYGVPGNPEGGHHHGEGEEGEEEEGEGGEGGEEIVSIDLRQFRADLRGELDLG
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEHHHHHHHHHHCCCEECC
DGFFDTLITRAGFSDYTHTEFEGDEVGTVFDVQGFEARAELAQTRRNGWGGNTGVQFYLR
CHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHH
DFVAFGAEAYVPKNTTTQFAVFTLQEFDLGGVQLEVAGRYETTDIESTTVGIERKFDTFS
HHHHCCCCEECCCCCCCEEEEEEEEECCCCCEEEEEECCEECCCCCCEEECEEECCCHHH
GALSLSRETESGLRFGVNVSRAERAPSAEELLSNGPHIATQAFEIGDPDLSVESAWGVEA
HHEEECCCCCCCCEECCCHHHHHCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHH
YLRGRIGPATISLAAYRNWFDDFIYLQDTGLEEDELPVFVYLQQGATYTGFEGEIEFPLI
HHCCCCCCCEEEHHHHHHHHHCEEEEEECCCCCCCCCEEEEEECCCEECCCCCEEEEEEE
DSGPFRLTTDLHVEYVDADLDDGSSVPRTPPLSLLGALEADWEQFNIRGEVQWFDDQDSV
CCCCEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHEEEEEEEEEECCCCCC
SAFETPTDGFTFVNASIAWRPIRGDNNVTLLLQAENIFDVTGRRHASFTKDFVPLAGRNI
CCCCCCCCCEEEEEEEEEEEEECCCCCEEEEEEECCEEECCCCCCCCCCCCCHHHCCCCC
KGSVRFSF
CCEEEECC
>Mature Secondary Structure 
TSNASPLRSAVSAIALASAFAAAPLAAQDETDDDQRASQQADDDFHNRSRDLPPEIVVT
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHHCCCCCCCCEEEE
AAGLTQLDVLAGTSVLEGFELQRSLDGTLGDTLVKIPGVSSTGFAPGSSRPVLRGLQGER
ECCCCEEHHHHCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCE
VRVLIDGLGAIDVSNTSVDHAVTIDVLTAERIDILRGPAVLLYGSSAIGGAVNVIDKRIP
EEEEEECCCEEEECCCCCCCEEEEEEEEHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCC
RRIPDEKIHIDGLVRGDTALDTREFGASLDAPLGSMFVFHVDGSYRNTNDLEIAGFQIAP
CCCCCCEEEEEEEEECCCCCCHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECC
DLRADLLADADEEEEEGEFEEADEMREAANQTGFVPNSATETWTANAGLTFFSGDSNLGF
CHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEECCCCCCE
AVGWYDTRYGVPGNPEGGHHHGEGEEGEEEEGEGGEGGEEIVSIDLRQFRADLRGELDLG
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEHHHHHHHHHHCCCEECC
DGFFDTLITRAGFSDYTHTEFEGDEVGTVFDVQGFEARAELAQTRRNGWGGNTGVQFYLR
CHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHH
DFVAFGAEAYVPKNTTTQFAVFTLQEFDLGGVQLEVAGRYETTDIESTTVGIERKFDTFS
HHHHCCCCEECCCCCCCEEEEEEEEECCCCCEEEEEECCEECCCCCCEEECEEECCCHHH
GALSLSRETESGLRFGVNVSRAERAPSAEELLSNGPHIATQAFEIGDPDLSVESAWGVEA
HHEEECCCCCCCCEECCCHHHHHCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHH
YLRGRIGPATISLAAYRNWFDDFIYLQDTGLEEDELPVFVYLQQGATYTGFEGEIEFPLI
HHCCCCCCCEEEHHHHHHHHHCEEEEEECCCCCCCCCEEEEEECCCEECCCCCEEEEEEE
DSGPFRLTTDLHVEYVDADLDDGSSVPRTPPLSLLGALEADWEQFNIRGEVQWFDDQDSV
CCCCEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHEEEEEEEEEECCCCCC
SAFETPTDGFTFVNASIAWRPIRGDNNVTLLLQAENIFDVTGRRHASFTKDFVPLAGRNI
CCCCCCCCCEEEEEEEEEEEEECCCCCEEEEEEECCEEECCCCCCCCCCCCCHHHCCCCC
KGSVRFSF
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]