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The map label for this gene is tal

Identifier: 85374568

GI number: 85374568

Start: 1773654

End: 1774307

Strand: Reverse

Name: tal

Synonym: ELI_08705

Alternate gene names: 85374568

Gene position: 1774307-1773654 (Counterclockwise)

Preceding gene: 85374569

Following gene: 85374567

Centisome position: 58.13

GC content: 60.4

Gene sequence:

>654_bases
ATGCAATTCTTCGCCGACACCGCTGAAATCGACGACATCAAGGAACTGGCCGCGACCGGCCTGCTCGATGGCGTGACCAC
CAATCCCTCGCTGATCCACAAGTCGGGCCGCGACTTCATCGAAGTGACGAAGGAGATCTGCGGTATCACCGACGGGCCGG
TGAGCGCCGAGGTCGTCGCGCTCGATCACGCCACGATGATGAAGGAAGCCGACAAACTGCGCGCGATCGCGGACAATGTC
TGCATCAAGGTGCCGCTGACGATCGACGGGCTCAAGACCTGCAAGGCGCTGAGCGATGACGGCACCATGGTCAACGTCAC
GCTCTGCTTCAGCGCCAACCAGGCGCTGCTGGCAGCGAAAGCGGGTGCGACATTCGTTTCGCCCTTCGTCGGCCGTCACG
ACGACAACGGTTTCAACGGCATGGAGCTGATCCGCGATATCCGCACGATCTACGACAATTATGCTTTCGAGACCGAAATC
CTCGTCGCCAGCGTGCGCCACACCACGCATGTGCTGGAAGCCGCGCTGATCGGCGCGGATGTCATGACGGCACCGCCCAA
GGTGATCATGGCGCTGGCGAACCATGTGCTGACCAACAAAGGCATCGAAGGCTTCCTCAAGGATTGGGAAGCGACGGGGC
AGAGTATCTTGTAA

Upstream 100 bases:

>100_bases
TGCTGCGTCGCGGCTGTGAGCCTGACCGATAGGCGGGGCTAGCCCCCGTGGGCACGGTTCGGTAGGAGATCGGGGAATCA
CTATTCGGAGCAGCCGCCCC

Downstream 100 bases:

>100_bases
TTGGCATGTGTCCCTGCGCAGGCAGGGACCTCCTTCCACCGGCGGATCGCTAGTGGTTGGAGGCCCCAGCCTTCGCTGGG
GCTCGCAAGGATTGTATGAG

Product: putative translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MQFFADTAEIDDIKELAATGLLDGVTTNPSLIHKSGRDFIEVTKEICGITDGPVSAEVVALDHATMMKEADKLRAIADNV
CIKVPLTIDGLKTCKALSDDGTMVNVTLCFSANQALLAAKAGATFVSPFVGRHDDNGFNGMELIRDIRTIYDNYAFETEI
LVASVRHTTHVLEAALIGADVMTAPPKVIMALANHVLTNKGIEGFLKDWEATGQSIL

Sequences:

>Translated_217_residues
MQFFADTAEIDDIKELAATGLLDGVTTNPSLIHKSGRDFIEVTKEICGITDGPVSAEVVALDHATMMKEADKLRAIADNV
CIKVPLTIDGLKTCKALSDDGTMVNVTLCFSANQALLAAKAGATFVSPFVGRHDDNGFNGMELIRDIRTIYDNYAFETEI
LVASVRHTTHVLEAALIGADVMTAPPKVIMALANHVLTNKGIEGFLKDWEATGQSIL
>Mature_217_residues
MQFFADTAEIDDIKELAATGLLDGVTTNPSLIHKSGRDFIEVTKEICGITDGPVSAEVVALDHATMMKEADKLRAIADNV
CIKVPLTIDGLKTCKALSDDGTMVNVTLCFSANQALLAAKAGATFVSPFVGRHDDNGFNGMELIRDIRTIYDNYAFETEI
LVASVRHTTHVLEAALIGADVMTAPPKVIMALANHVLTNKGIEGFLKDWEATGQSIL

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=178, Percent_Identity=30.3370786516854, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI87081788, Length=214, Percent_Identity=31.3084112149533, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1790382, Length=213, Percent_Identity=32.8638497652582, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788807, Length=202, Percent_Identity=30.1980198019802, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1786189, Length=172, Percent_Identity=29.0697674418605, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25153750, Length=245, Percent_Identity=28.9795918367347, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321480, Length=196, Percent_Identity=27.0408163265306, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI45549185, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_ERYLH (Q2N908)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458630.1
- HSSP:   Q9WYD1
- ProteinModelPortal:   Q2N908
- STRING:   Q2N908
- GeneID:   3868942
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_08705
- NMPDR:   fig|314225.3.peg.1303
- eggNOG:   COG0176
- HOGENOM:   HBG533000
- OMA:   IHKNIVI
- PhylomeDB:   Q2N908
- ProtClustDB:   PRK01362
- BioCyc:   ELIT314225:ELI_08705-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 23293; Mature: 23293

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFFADTAEIDDIKELAATGLLDGVTTNPSLIHKSGRDFIEVTKEICGITDGPVSAEVVA
CCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEE
LDHATMMKEADKLRAIADNVCIKVPLTIDGLKTCKALSDDGTMVNVTLCFSANQALLAAK
EHHHHHHHHHHHHHHHHCCEEEEEEEEECHHHHHHHCCCCCCEEEEEEEECCCCEEEEHH
AGATFVSPFVGRHDDNGFNGMELIRDIRTIYDNYAFETEILVASVRHTTHVLEAALIGAD
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCH
VMTAPPKVIMALANHVLTNKGIEGFLKDWEATGQSIL
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQFFADTAEIDDIKELAATGLLDGVTTNPSLIHKSGRDFIEVTKEICGITDGPVSAEVVA
CCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEE
LDHATMMKEADKLRAIADNVCIKVPLTIDGLKTCKALSDDGTMVNVTLCFSANQALLAAK
EHHHHHHHHHHHHHHHHCCEEEEEEEEECHHHHHHHCCCCCCEEEEEEEECCCCEEEEHH
AGATFVSPFVGRHDDNGFNGMELIRDIRTIYDNYAFETEILVASVRHTTHVLEAALIGAD
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCH
VMTAPPKVIMALANHVLTNKGIEGFLKDWEATGQSIL
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA