| Definition | Erythrobacter litoralis HTCC2594 chromosome, complete genome. |
|---|---|
| Accession | NC_007722 |
| Length | 3,052,398 |
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The map label for this gene is cobT [H]
Identifier: 85374567
GI number: 85374567
Start: 1771741
End: 1773558
Strand: Reverse
Name: cobT [H]
Synonym: ELI_08700
Alternate gene names: 85374567
Gene position: 1773558-1771741 (Counterclockwise)
Preceding gene: 85374568
Following gene: 85374566
Centisome position: 58.1
GC content: 66.61
Gene sequence:
>1818_bases ATGAGCGACGAATCCCCCCTCGACAGCTTCAAGCGCGCGCTGACCGGCACGGCGCGGGCCCTTGCGCGCGAGCCGGAGAT CGAAGTCGCGTGGAGCGCCGACAGCCCGAGCGCGCAGGGGCGGAATTTCCGCGTACCGCTGCCCGGTCGCAATCTGCCGC CCGAGCAGGCCGCCGAGGCGCGCGGCTTCGCGGACAGTTTCGCGCTCAAGCTGCGCCACCACAATCTGAAGCTGCACGAG GCCAACGCGCCCAGCGATCCGGTGGCGCGGGCGTGCTACGATGCGGTCGAGCAGGTCCGCTACGAAGCATTGGGCGCGAG CGGCTACGAAGGGATTGCGGACAATCTCGACGCCGCGGTCGAACTGCGCACCGCCAGCGATCCCATTGCCCGCGCGCAGA ACGACGGCGACGTGCCGCTGCAAAGCGCGCTCGGCCTGATGCTGCGCGAGCAATTGACCGGCAAGCCGATTCCCGAACGG GCGCGTGCCGGCGTCGAACTGGTGCGCGAGTATATCGAGAGCCGAACCGGCAGCGATTTCGAGGATTTGGCCGGGTCGCT CGAGGACCAGAAAGCGTTCCAGTCGCTCGCGCTCGACATGCTGCGGCATCTCGAACTGACCGATCCGACCGATCAGCCCG ACAGCGCCGACAATGAAGATGGCGAGGACGAAGACGGGCAGGACGAGCAGGAAGACGAGAGCGACGACGAAACCGGCGGC GACGAGCAGCCGAGCCCTGCGGAAATGGCCGGCGAGCAGACCGAAGGCGACGCCGAGGGCGAGGCGGAAACCGAGGCCGG CGAGGAAGTGGCCGACGGCGAGCTGGGCGACGAGGGCGAGGAAGGCATGATGCCGGTCCGCCCCAACCGCCCGTGGACCG ACCTGCCCGACAGCTTCGACTACACCGAATACACCACGCAATATGACGAGGAAATCGCCGCGGCCGAACTGTGCGATGCC GAGGAACTGGACCGGCTGCGGGCCTATCTCGATAGCCAGCTGACAGGGCTGCAGGGCGTCGTCACCCGGCTCGCCAACCG GCTCCAGCGCCGCCTGATGGCGCAGCAGAATCGTAGCTGGGATTTCGACCAGGAAGAGGGGTTGCTCGATGCCGCGCGGC TGGCTCGTGTCGTCATCAGCCCCGGCCATTCGCTGAGCTACAAGATCGAGCGCGATACCGAGTTCAAGGACACGGTCGTC ACCCTGCTGATCGACAATTCCGGCTCCATGCGCGGGCGGCCGATCAGCATCGCCGCAATCAGCGCCGACATCATGGCGCG CACGCTGGAGCGGTGCGGGGTCAAGACCGAGATCCTCGGCTTCACGACCCGCGCGTGGAAGGGCGGGCAGGCGCGCGAGA AATGGCTCGCCGACGGCAAGCCGCCGCAGCCCGGCCGCCTCAATGACCTCCGCCACATCCTCTACAAAAAGGCCGACGAA CCCTGGCGCCGCGCGCGCCGCAATCTCGGCCTGATGATGCGCGAAGGGCTGCTCAAGGAAAACATCGACGGCGAGGCGCT GCTGTGGGCGCATAATCGCCTGATCGCGCGACCCGAGGATCGCCGCATCCTGATGGTGATCAGCGACGGCGCGCCGGTCG ACGACAGCACGCTCAGCGTCAACAGCGCGGGCTATCTCGAAAGCCACTTGCGCAAGGTGATCGACTGGATCGAGAAGCAG TCACCCGTGCAACTGGTGGCCGTCGGCATCGGCCACGATGTGACCCGCTATTACAAGCGCGCGGTGACGATCATGGATGT CGAACAGCTCGGCGGGACGATTATCGAGCAGCTAGCCGATTTGTTTGAGGTGGAGTGA
Upstream 100 bases:
>100_bases TGTAATTGGCATGTGTCCCTGCGCAGGCAGGGACCTCCTTCCACCGGCGGATCGCTAGTGGTTGGAGGCCCCAGCCTTCG CTGGGGCTCGCAAGGATTGT
Downstream 100 bases:
>100_bases TGGTATTCGGCCTGTTTGATCGACCCAGTCTTAAGATTGCGAAACATGTTCCCGATTGGGCCAGAGAAACCGTCGTCAAC TGCGAATGCGTTATTGGAAA
Product: cobalamin biosynthesis protein
Products: NA
Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobT [H]
Number of amino acids: Translated: 605; Mature: 604
Protein sequence:
>605_residues MSDESPLDSFKRALTGTARALAREPEIEVAWSADSPSAQGRNFRVPLPGRNLPPEQAAEARGFADSFALKLRHHNLKLHE ANAPSDPVARACYDAVEQVRYEALGASGYEGIADNLDAAVELRTASDPIARAQNDGDVPLQSALGLMLREQLTGKPIPER ARAGVELVREYIESRTGSDFEDLAGSLEDQKAFQSLALDMLRHLELTDPTDQPDSADNEDGEDEDGQDEQEDESDDETGG DEQPSPAEMAGEQTEGDAEGEAETEAGEEVADGELGDEGEEGMMPVRPNRPWTDLPDSFDYTEYTTQYDEEIAAAELCDA EELDRLRAYLDSQLTGLQGVVTRLANRLQRRLMAQQNRSWDFDQEEGLLDAARLARVVISPGHSLSYKIERDTEFKDTVV TLLIDNSGSMRGRPISIAAISADIMARTLERCGVKTEILGFTTRAWKGGQAREKWLADGKPPQPGRLNDLRHILYKKADE PWRRARRNLGLMMREGLLKENIDGEALLWAHNRLIARPEDRRILMVISDGAPVDDSTLSVNSAGYLESHLRKVIDWIEKQ SPVQLVAVGIGHDVTRYYKRAVTIMDVEQLGGTIIEQLADLFEVE
Sequences:
>Translated_605_residues MSDESPLDSFKRALTGTARALAREPEIEVAWSADSPSAQGRNFRVPLPGRNLPPEQAAEARGFADSFALKLRHHNLKLHE ANAPSDPVARACYDAVEQVRYEALGASGYEGIADNLDAAVELRTASDPIARAQNDGDVPLQSALGLMLREQLTGKPIPER ARAGVELVREYIESRTGSDFEDLAGSLEDQKAFQSLALDMLRHLELTDPTDQPDSADNEDGEDEDGQDEQEDESDDETGG DEQPSPAEMAGEQTEGDAEGEAETEAGEEVADGELGDEGEEGMMPVRPNRPWTDLPDSFDYTEYTTQYDEEIAAAELCDA EELDRLRAYLDSQLTGLQGVVTRLANRLQRRLMAQQNRSWDFDQEEGLLDAARLARVVISPGHSLSYKIERDTEFKDTVV TLLIDNSGSMRGRPISIAAISADIMARTLERCGVKTEILGFTTRAWKGGQAREKWLADGKPPQPGRLNDLRHILYKKADE PWRRARRNLGLMMREGLLKENIDGEALLWAHNRLIARPEDRRILMVISDGAPVDDSTLSVNSAGYLESHLRKVIDWIEKQ SPVQLVAVGIGHDVTRYYKRAVTIMDVEQLGGTIIEQLADLFEVE >Mature_604_residues SDESPLDSFKRALTGTARALAREPEIEVAWSADSPSAQGRNFRVPLPGRNLPPEQAAEARGFADSFALKLRHHNLKLHEA NAPSDPVARACYDAVEQVRYEALGASGYEGIADNLDAAVELRTASDPIARAQNDGDVPLQSALGLMLREQLTGKPIPERA RAGVELVREYIESRTGSDFEDLAGSLEDQKAFQSLALDMLRHLELTDPTDQPDSADNEDGEDEDGQDEQEDESDDETGGD EQPSPAEMAGEQTEGDAEGEAETEAGEEVADGELGDEGEEGMMPVRPNRPWTDLPDSFDYTEYTTQYDEEIAAAELCDAE ELDRLRAYLDSQLTGLQGVVTRLANRLQRRLMAQQNRSWDFDQEEGLLDAARLARVVISPGHSLSYKIERDTEFKDTVVT LLIDNSGSMRGRPISIAAISADIMARTLERCGVKTEILGFTTRAWKGGQAREKWLADGKPPQPGRLNDLRHILYKKADEP WRRARRNLGLMMREGLLKENIDGEALLWAHNRLIARPEDRRILMVISDGAPVDDSTLSVNSAGYLESHLRKVIDWIEKQS PVQLVAVGIGHDVTRYYKRAVTIMDVEQLGGTIIEQLADLFEVE
Specific function: Catalyzes cobalt insertion in the corrin ring [H]
COG id: COG4547
COG function: function code H; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)
Gene ontology:
Cell location: Cytoplasm (Potential) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 VWFA domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006538 - InterPro: IPR002035 [H]
Pfam domain/function: PF06213 CobT [H]
EC number: =6.6.1.2 [H]
Molecular weight: Translated: 67033; Mature: 66902
Theoretical pI: Translated: 4.25; Mature: 4.25
Prosite motif: PS50234 VWFA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSDESPLDSFKRALTGTARALAREPEIEVAWSADSPSAQGRNFRVPLPGRNLPPEQAAEA CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCCCCHHHHHHH RGFADSFALKLRHHNLKLHEANAPSDPVARACYDAVEQVRYEALGASGYEGIADNLDAAV CCCHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEE ELRTASDPIARAQNDGDVPLQSALGLMLREQLTGKPIPERARAGVELVREYIESRTGSDF EEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCH EDLAGSLEDQKAFQSLALDMLRHLELTDPTDQPDSADNEDGEDEDGQDEQEDESDDETGG HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC DEQPSPAEMAGEQTEGDAEGEAETEAGEEVADGELGDEGEEGMMPVRPNRPWTDLPDSFD CCCCCHHHHCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC YTEYTTQYDEEIAAAELCDAEELDRLRAYLDSQLTGLQGVVTRLANRLQRRLMAQQNRSW CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC DFDQEEGLLDAARLARVVISPGHSLSYKIERDTEFKDTVVTLLIDNSGSMRGRPISIAAI CCCHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCEEEEEH SADIMARTLERCGVKTEILGFTTRAWKGGQAREKWLADGKPPQPGRLNDLRHILYKKADE HHHHHHHHHHHCCCCCHHHHCCHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC PWRRARRNLGLMMREGLLKENIDGEALLWAHNRLIARPEDRRILMVISDGAPVDDSTLSV HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCCEEEEEEECCCCCCCCCEEC NSAGYLESHLRKVIDWIEKQSPVQLVAVGIGHDVTRYYKRAVTIMDVEQLGGTIIEQLAD CCCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHEEEHHHHHHHHHHHHHH LFEVE HHCCC >Mature Secondary Structure SDESPLDSFKRALTGTARALAREPEIEVAWSADSPSAQGRNFRVPLPGRNLPPEQAAEA CCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCCCCHHHHHHH RGFADSFALKLRHHNLKLHEANAPSDPVARACYDAVEQVRYEALGASGYEGIADNLDAAV CCCHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEE ELRTASDPIARAQNDGDVPLQSALGLMLREQLTGKPIPERARAGVELVREYIESRTGSDF EEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCH EDLAGSLEDQKAFQSLALDMLRHLELTDPTDQPDSADNEDGEDEDGQDEQEDESDDETGG HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC DEQPSPAEMAGEQTEGDAEGEAETEAGEEVADGELGDEGEEGMMPVRPNRPWTDLPDSFD CCCCCHHHHCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC YTEYTTQYDEEIAAAELCDAEELDRLRAYLDSQLTGLQGVVTRLANRLQRRLMAQQNRSW CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC DFDQEEGLLDAARLARVVISPGHSLSYKIERDTEFKDTVVTLLIDNSGSMRGRPISIAAI CCCHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCEEEEEH SADIMARTLERCGVKTEILGFTTRAWKGGQAREKWLADGKPPQPGRLNDLRHILYKKADE HHHHHHHHHHHCCCCCHHHHCCHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC PWRRARRNLGLMMREGLLKENIDGEALLWAHNRLIARPEDRRILMVISDGAPVDDSTLSV HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCCEEEEEEECCCCCCCCCEEC NSAGYLESHLRKVIDWIEKQSPVQLVAVGIGHDVTRYYKRAVTIMDVEQLGGTIIEQLAD CCCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHEEEHHHHHHHHHHHHHH LFEVE HHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 1917840 [H]