Click here to switch to the map view.

The map label for this gene is asd [H]

Identifier: 85374313

GI number: 85374313

Start: 1541070

End: 1542095

Strand: Reverse

Name: asd [H]

Synonym: ELI_07430

Alternate gene names: 85374313

Gene position: 1542095-1541070 (Counterclockwise)

Preceding gene: 85374315

Following gene: 85374312

Centisome position: 50.52

GC content: 61.6

Gene sequence:

>1026_bases
GTGGGCTATCGCGTAGCCGTGGTCGGAGCGACCGGGAATGTCGGCCGGGAAATAATGCAGATCCTCGCCGAGCGCGAGTT
TCCGTGCGACGAAGTGGCGGCGGTCGCTTCTTCACGCTCGCACGGGACGGAAGTCGAATTCGGCGACACCGGCAAGATGC
TCAAGTGCAGAAATATCGAGCATTTCGACTGGGCCGGCTGGGACATCGCGCTGTTCTCTGCCGGCTCCGGCCCGGCCAAG
GAATATGCCCCCAAAGCCGCGGCGGCGGGCTGCGTGGTGATCGACAACAGTTCGCTCTACCGTATGGACCCGGATGTGCC
GCTGATCGTGCCCGAAGTGAACCCGGACGCGATCGACGAATACAAAAAGAAGAACATCATCGCCAATCCCAACTGCTCGA
CCGCGCAATTGGTGGTCGCGCTCAAGCCGTTGCACGATGCAGCCACGATCAAGCGGGTGGTCGTGAGCACCTACCAGTCG
GTTTCCGGTGCCGGGAAAGCGGGCATGGACGAGCTGTTCCAGCAAAGCCGCGCGATCTTCGTCGGTGACCCGGTAGTGCC
GGAGAAATTCACCAAGCAGATCGCGTTCAACGTCATCCCCCACATCGACGTCTTCATGGATGACGGCGCGACCAAGGAAG
AGTGGAAGATGGTGGTCGAGACCAAGAAAATCCTCGACTCCAGGATCAAATTGAACGCCACCTGCGTACGCGTTCCGGTG
TTCGTCGGCCATTCCGAAGCGGTGAACATCGAATTCGAGAACGAGCTCGGCGCGGAACAGGCGATGGAAATCCTGCGTGA
GGCGCCCGGCATCATGCTGGTCGATAAGCGCGAGGACGGCGGTTACGTCACTCCGGTAGAAAGCGCAGGCGATGGCGCGA
CCTATGTCAGCCGCGTGCGCGAAGACCCGACGGTCGAGAACGGCCTGACGCTGTGGTGCGTATCCGACAATCTGCGCAAG
GGCGCCGCGCTCAATGCCGTGCAGATCGCCGAGCTGCTCGGGCGGCGGCATCTGAAGAAGGGGTAG

Upstream 100 bases:

>100_bases
ATAGCTATTCTCTCCCGTCGCACCCGCCTAGGGGCTTTCCATGCAGCTATCGCGCGACTACCTGCCACACGCAAAGCAGT
TTTGATGTCGGAGAAGTGAA

Downstream 100 bases:

>100_bases
GGCGATGCGCGTAATCTTGGGGCTGGCGGCACTTCTCGCGCTGGGCGCATGCGGCAGCGATGTCCCGTCGCCGGCGGAGC
GGCTGCAGCAGGAAAACGGA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MGYRVAVVGATGNVGREIMQILAEREFPCDEVAAVASSRSHGTEVEFGDTGKMLKCRNIEHFDWAGWDIALFSAGSGPAK
EYAPKAAAAGCVVIDNSSLYRMDPDVPLIVPEVNPDAIDEYKKKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQS
VSGAGKAGMDELFQQSRAIFVGDPVVPEKFTKQIAFNVIPHIDVFMDDGATKEEWKMVVETKKILDSRIKLNATCVRVPV
FVGHSEAVNIEFENELGAEQAMEILREAPGIMLVDKREDGGYVTPVESAGDGATYVSRVREDPTVENGLTLWCVSDNLRK
GAALNAVQIAELLGRRHLKKG

Sequences:

>Translated_341_residues
MGYRVAVVGATGNVGREIMQILAEREFPCDEVAAVASSRSHGTEVEFGDTGKMLKCRNIEHFDWAGWDIALFSAGSGPAK
EYAPKAAAAGCVVIDNSSLYRMDPDVPLIVPEVNPDAIDEYKKKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQS
VSGAGKAGMDELFQQSRAIFVGDPVVPEKFTKQIAFNVIPHIDVFMDDGATKEEWKMVVETKKILDSRIKLNATCVRVPV
FVGHSEAVNIEFENELGAEQAMEILREAPGIMLVDKREDGGYVTPVESAGDGATYVSRVREDPTVENGLTLWCVSDNLRK
GAALNAVQIAELLGRRHLKKG
>Mature_340_residues
GYRVAVVGATGNVGREIMQILAEREFPCDEVAAVASSRSHGTEVEFGDTGKMLKCRNIEHFDWAGWDIALFSAGSGPAKE
YAPKAAAAGCVVIDNSSLYRMDPDVPLIVPEVNPDAIDEYKKKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSV
SGAGKAGMDELFQQSRAIFVGDPVVPEKFTKQIAFNVIPHIDVFMDDGATKEEWKMVVETKKILDSRIKLNATCVRVPVF
VGHSEAVNIEFENELGAEQAMEILREAPGIMLVDKREDGGYVTPVESAGDGATYVSRVREDPTVENGLTLWCVSDNLRKG
AALNAVQIAELLGRRHLKKG

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=340, Percent_Identity=38.5294117647059, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI1789841, Length=359, Percent_Identity=27.5766016713092, Blast_Score=98, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6320362, Length=406, Percent_Identity=30.0492610837438, Blast_Score=97, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37046; Mature: 36914

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS01103 ASD ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYRVAVVGATGNVGREIMQILAEREFPCDEVAAVASSRSHGTEVEFGDTGKMLKCRNIE
CCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEECCCC
HFDWAGWDIALFSAGSGPAKEYAPKAAAAGCVVIDNSSLYRMDPDVPLIVPEVNPDAIDE
CCCCCCCEEEEEECCCCCHHHHCCHHHHCCEEEEECCCEEEECCCCCEEEECCCHHHHHH
YKKKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVSGAGKAGMDELFQQSRAIF
HHHCCEECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCEEE
VGDPVVPEKFTKQIAFNVIPHIDVFMDDGATKEEWKMVVETKKILDSRIKLNATCVRVPV
ECCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHEECEEEEEEEE
FVGHSEAVNIEFENELGAEQAMEILREAPGIMLVDKREDGGYVTPVESAGDGATYVSRVR
EECCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCHHHHHHHH
EDPTVENGLTLWCVSDNLRKGAALNAVQIAELLGRRHLKKG
CCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GYRVAVVGATGNVGREIMQILAEREFPCDEVAAVASSRSHGTEVEFGDTGKMLKCRNIE
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEECCCC
HFDWAGWDIALFSAGSGPAKEYAPKAAAAGCVVIDNSSLYRMDPDVPLIVPEVNPDAIDE
CCCCCCCEEEEEECCCCCHHHHCCHHHHCCEEEEECCCEEEECCCCCEEEECCCHHHHHH
YKKKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVSGAGKAGMDELFQQSRAIF
HHHCCEECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCEEE
VGDPVVPEKFTKQIAFNVIPHIDVFMDDGATKEEWKMVVETKKILDSRIKLNATCVRVPV
ECCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHEECEEEEEEEE
FVGHSEAVNIEFENELGAEQAMEILREAPGIMLVDKREDGGYVTPVESAGDGATYVSRVR
EECCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCHHHHHHHH
EDPTVENGLTLWCVSDNLRKGAALNAVQIAELLGRRHLKKG
CCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]