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The map label for this gene is yciR [C]

Identifier: 85374282

GI number: 85374282

Start: 1506902

End: 1509124

Strand: Reverse

Name: yciR [C]

Synonym: ELI_07275

Alternate gene names: 85374282

Gene position: 1509124-1506902 (Counterclockwise)

Preceding gene: 85374283

Following gene: 85374281

Centisome position: 49.44

GC content: 59.87

Gene sequence:

>2223_bases
ATGGCAATCGGAAATTTCTTCTCGAAGAGGCATGTCAAGGGTGGCGGCGATGCCACTGGATCGCGCGCGATCGGCAAGAC
CGATCCGCGCCGGCTGTCGTTGCTCGACGATTTCGAAAGCGCCGACCTGGGCTGGTTCTGGGCAACCGATTCCGAATCCA
AGCTTATCTATCTTTCAGAAAATGCAGCAGCCCAGTTCGGCTGCAGTGCCGACGAACTGATCGGCAAGCCCCTGTCCGAA
CTCTTCATCCTGGAGAGGGGAGAGGAAGAAAAGGGCGAGCAATCGCCGCAAAGGCCGCTGCCGTTCTTGCTGCGTGCACG
AAACACCATCTCCGACCTGCCGGTTCGCATTTCTATTGGAGAGAGTGACGACAGAAAGATCTGGTGGTCCATCTCTGGTA
AGCCCCAGCTCGACGGAAATGGCGATCTGCTGGGCTATCGTGGCAGCGCCAAGGACATAACGGCCGTACGCCAAAACCAG
CTCGAGGTTGGCCGTATGGCGCAATATGACTCGCTGACGGGTCTCGCCAATCGCCACCGCATGACCAAGCGGCTGACCAC
GACGCTGACAGCCTATAAGGCTGCCAAGCGTTCTTGCGCGCTGATGATGCTCGACCTCGACCGTTTCAAGCAGGTGAACG
ACACGCTCGGGCATCCCGCGGGCGACGAGCTGCTCAAACAGGTCGGCCAGCGTCTTGAACGCATTATCGGCGGCAACGGT
GAAATCGGGCGTTTGGGTGGCGATGAATTTCAGGTGATCCTGCCCGACATCGAGGATCGCGGGCGGCTCGGCGAAGTCGC
GGCGCGCGTTATCCAGATGATCTCGCAGCCCTATTCGATCGATGGAGCGCGCGCGATTATCGGCACGTCGGTGGGAATTG
CGATCGCGCCCTATGACGGCATCGATACCGAAGAACTCGTCGGCGCCGCGGACCTTGCACTCTACGCCGCGAAAGGCGGC
GGGCGCGGTCAGTACCGTTTTTATTCCAGCGAACTGAAGGACGGTGCGCGGCATCGTCGTGAAATCGAGGAAGACCTGCG
CGATGCCCTGTCCATGGATCAGGGGTTGGAGATGCACTACCAGCCGCTGGTCGACGCCAAGACACACAGGGTCAAATGTT
TCGAAGCGCTGATCCGCTGGAATCATCCGGAGCGGGGCTGGATAAGTCCGGGTGACTTCATCCCGGTCGCCGAAGACACC
AACCAGATCGGCGATCTGGGCGAATGGGTTCTCCGCAGGGTATGTACAGATGCATCTTCCTGGCCAGGCGATATTTCGGT
CGCGGTAAACGTCTCGGCCGTGCAGTTTGGCGATCCGAACCTTCCGCAGATCGTCTGCAAGGCACTGAAGGATTCGGGCC
TTGATCCGAGGCGGCTCGAGCTCGAGCTGACCGAGAGCGTTTTCATCGGCGATCCCAATGCGACGCATGATATGTTCGTT
GCGCTTAAAAAGCTTGGCGTGGCGCTGGCGCTCGATGATTTCGGCACCGGCTATTCATCGCTCGGCTATCTGAAGAACGC
GCCGTTCGACAAGATCAAGATCGACCAGAGCTTCGTTCGCGGATCGACCGAGAACGACAACAACAATTCTGCCATCATCA
CAGCGATTGTAAGCCTTGCCGGCGCGCTCAACATGACCACGGTGGCAGAAGGCGTCGAGGCCATGGACGAGCTTGAACTC
GTGCGGGAACGCGGCGCGACCTACATACAGGGCTTCATCTTCTCGAAAGCGATCCCGCAGGATGTCGTGCTCGAGAAACT
GGAAAGCGGCGACTTGGCATTCGAGCCCAACGGTCCGGCCAAGCATCGGTCGGAACGCAAATCGGTATTTCGCAGGATTG
GCGTAATTCATGAAGATCATCGCTACGATGCGGTGCTGCGCAACCTGTCCAAGACAGGCGCACGGATCGAAGGCATTCTC
AACGTTCCGCTGGGGACCCAACTGGTCCTCGACCTGGGCGAGGGGCAATTGGTCGTGGGGGCCGTCCGACGCTCCGTCGA
GGCTGAGCAGGGCATCGAATTCGAGACTCCGCTGATCAGCGACGGTGCCGATGGGTTGTGCACCCGCCATCGCGTCTCGC
CATATATGCTGGCCTCGGCGGGCATGCCGCTGGCGGCGCTTCCTCCGGGACACTATCCCCTGACCAACCGGTCGGACGGC
CAAAAATCCCGACCGCAATTCATGCAGCTGGACCTCACATCAGACGCCGCCCGCGCGGCTTGA

Upstream 100 bases:

>100_bases
TTAACTGCTTGGTAGGCATAAGAATGTAAGGCTGTCAGCCGGGAAAAATATAATCAGGTTCGCGCATCGGAGACATCGAT
CGGGATGAATTGAGCAAGTA

Downstream 100 bases:

>100_bases
TCCCCACGTTCGCAAAGCGACCGCTGTAACCTCCCGACCGAACCGAGCGATGAAGGCACTGACGCCTCACGTTTGAAAGG
ATGGAACGATGTTCAAGACT

Product: sensory box/GGDEF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 740; Mature: 739

Protein sequence:

>740_residues
MAIGNFFSKRHVKGGGDATGSRAIGKTDPRRLSLLDDFESADLGWFWATDSESKLIYLSENAAAQFGCSADELIGKPLSE
LFILERGEEEKGEQSPQRPLPFLLRARNTISDLPVRISIGESDDRKIWWSISGKPQLDGNGDLLGYRGSAKDITAVRQNQ
LEVGRMAQYDSLTGLANRHRMTKRLTTTLTAYKAAKRSCALMMLDLDRFKQVNDTLGHPAGDELLKQVGQRLERIIGGNG
EIGRLGGDEFQVILPDIEDRGRLGEVAARVIQMISQPYSIDGARAIIGTSVGIAIAPYDGIDTEELVGAADLALYAAKGG
GRGQYRFYSSELKDGARHRREIEEDLRDALSMDQGLEMHYQPLVDAKTHRVKCFEALIRWNHPERGWISPGDFIPVAEDT
NQIGDLGEWVLRRVCTDASSWPGDISVAVNVSAVQFGDPNLPQIVCKALKDSGLDPRRLELELTESVFIGDPNATHDMFV
ALKKLGVALALDDFGTGYSSLGYLKNAPFDKIKIDQSFVRGSTENDNNNSAIITAIVSLAGALNMTTVAEGVEAMDELEL
VRERGATYIQGFIFSKAIPQDVVLEKLESGDLAFEPNGPAKHRSERKSVFRRIGVIHEDHRYDAVLRNLSKTGARIEGIL
NVPLGTQLVLDLGEGQLVVGAVRRSVEAEQGIEFETPLISDGADGLCTRHRVSPYMLASAGMPLAALPPGHYPLTNRSDG
QKSRPQFMQLDLTSDAARAA

Sequences:

>Translated_740_residues
MAIGNFFSKRHVKGGGDATGSRAIGKTDPRRLSLLDDFESADLGWFWATDSESKLIYLSENAAAQFGCSADELIGKPLSE
LFILERGEEEKGEQSPQRPLPFLLRARNTISDLPVRISIGESDDRKIWWSISGKPQLDGNGDLLGYRGSAKDITAVRQNQ
LEVGRMAQYDSLTGLANRHRMTKRLTTTLTAYKAAKRSCALMMLDLDRFKQVNDTLGHPAGDELLKQVGQRLERIIGGNG
EIGRLGGDEFQVILPDIEDRGRLGEVAARVIQMISQPYSIDGARAIIGTSVGIAIAPYDGIDTEELVGAADLALYAAKGG
GRGQYRFYSSELKDGARHRREIEEDLRDALSMDQGLEMHYQPLVDAKTHRVKCFEALIRWNHPERGWISPGDFIPVAEDT
NQIGDLGEWVLRRVCTDASSWPGDISVAVNVSAVQFGDPNLPQIVCKALKDSGLDPRRLELELTESVFIGDPNATHDMFV
ALKKLGVALALDDFGTGYSSLGYLKNAPFDKIKIDQSFVRGSTENDNNNSAIITAIVSLAGALNMTTVAEGVEAMDELEL
VRERGATYIQGFIFSKAIPQDVVLEKLESGDLAFEPNGPAKHRSERKSVFRRIGVIHEDHRYDAVLRNLSKTGARIEGIL
NVPLGTQLVLDLGEGQLVVGAVRRSVEAEQGIEFETPLISDGADGLCTRHRVSPYMLASAGMPLAALPPGHYPLTNRSDG
QKSRPQFMQLDLTSDAARAA
>Mature_739_residues
AIGNFFSKRHVKGGGDATGSRAIGKTDPRRLSLLDDFESADLGWFWATDSESKLIYLSENAAAQFGCSADELIGKPLSEL
FILERGEEEKGEQSPQRPLPFLLRARNTISDLPVRISIGESDDRKIWWSISGKPQLDGNGDLLGYRGSAKDITAVRQNQL
EVGRMAQYDSLTGLANRHRMTKRLTTTLTAYKAAKRSCALMMLDLDRFKQVNDTLGHPAGDELLKQVGQRLERIIGGNGE
IGRLGGDEFQVILPDIEDRGRLGEVAARVIQMISQPYSIDGARAIIGTSVGIAIAPYDGIDTEELVGAADLALYAAKGGG
RGQYRFYSSELKDGARHRREIEEDLRDALSMDQGLEMHYQPLVDAKTHRVKCFEALIRWNHPERGWISPGDFIPVAEDTN
QIGDLGEWVLRRVCTDASSWPGDISVAVNVSAVQFGDPNLPQIVCKALKDSGLDPRRLELELTESVFIGDPNATHDMFVA
LKKLGVALALDDFGTGYSSLGYLKNAPFDKIKIDQSFVRGSTENDNNNSAIITAIVSLAGALNMTTVAEGVEAMDELELV
RERGATYIQGFIFSKAIPQDVVLEKLESGDLAFEPNGPAKHRSERKSVFRRIGVIHEDHRYDAVLRNLSKTGARIEGILN
VPLGTQLVLDLGEGQLVVGAVRRSVEAEQGIEFETPLISDGADGLCTRHRVSPYMLASAGMPLAALPPGHYPLTNRSDGQ
KSRPQFMQLDLTSDAARAA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=434, Percent_Identity=36.405529953917, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI87081921, Length=429, Percent_Identity=31.9347319347319, Blast_Score=213, Evalue=4e-56,
Organism=Escherichia coli, GI226510982, Length=404, Percent_Identity=27.970297029703, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1790496, Length=249, Percent_Identity=33.3333333333333, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=33.75, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788381, Length=469, Percent_Identity=26.6524520255864, Blast_Score=129, Evalue=8e-31,
Organism=Escherichia coli, GI1788502, Length=226, Percent_Identity=33.6283185840708, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87081845, Length=243, Percent_Identity=34.5679012345679, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1786507, Length=263, Percent_Identity=30.7984790874525, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI87081980, Length=229, Percent_Identity=32.7510917030568, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1787055, Length=253, Percent_Identity=31.6205533596838, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788849, Length=260, Percent_Identity=29.2307692307692, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=33.5443037974684, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081977, Length=151, Percent_Identity=38.4105960264901, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786584, Length=176, Percent_Identity=29.5454545454545, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082096, Length=396, Percent_Identity=24.2424242424242, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI145693134, Length=193, Percent_Identity=30.0518134715026, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081881, Length=176, Percent_Identity=30.6818181818182, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787802, Length=179, Percent_Identity=27.3743016759777, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1787410, Length=219, Percent_Identity=26.027397260274, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=31.547619047619, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI87081974, Length=157, Percent_Identity=32.484076433121, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787816, Length=161, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 80970; Mature: 80838

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGNFFSKRHVKGGGDATGSRAIGKTDPRRLSLLDDFESADLGWFWATDSESKLIYLSE
CCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCEEEEEEC
NAAAQFGCSADELIGKPLSELFILERGEEEKGEQSPQRPLPFLLRARNTISDLPVRISIG
CCCHHCCCCHHHHHCCCHHHHHHHCCCCHHHCCCCCCCCCHHHHHHCCHHHCCCEEEEEC
ESDDRKIWWSISGKPQLDGNGDLLGYRGSAKDITAVRQNQLEVGRMAQYDSLTGLANRHR
CCCCCEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTKRLTTTLTAYKAAKRSCALMMLDLDRFKQVNDTLGHPAGDELLKQVGQRLERIIGGNG
HHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
EIGRLGGDEFQVILPDIEDRGRLGEVAARVIQMISQPYSIDGARAIIGTSVGIAIAPYDG
CEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCC
IDTEELVGAADLALYAAKGGGRGQYRFYSSELKDGARHRREIEEDLRDALSMDQGLEMHY
CCHHHHHHHHHHEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QPLVDAKTHRVKCFEALIRWNHPERGWISPGDFIPVAEDTNQIGDLGEWVLRRVCTDASS
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCC
WPGDISVAVNVSAVQFGDPNLPQIVCKALKDSGLDPRRLELELTESVFIGDPNATHDMFV
CCCCEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECEEEECCCCCHHHHHH
ALKKLGVALALDDFGTGYSSLGYLKNAPFDKIKIDQSFVRGSTENDNNNSAIITAIVSLA
HHHHCCEEEEECCCCCCHHHCCHHCCCCCCEEECCHHHHCCCCCCCCCCHHHHHHHHHHH
GALNMTTVAEGVEAMDELELVRERGATYIQGFIFSKAIPQDVVLEKLESGDLAFEPNGPA
HHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCCCH
KHRSERKSVFRRIGVIHEDHRYDAVLRNLSKTGARIEGILNVPLGTQLVLDLGEGQLVVG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCEEHH
AVRRSVEAEQGIEFETPLISDGADGLCTRHRVSPYMLASAGMPLAALPPGHYPLTNRSDG
HHHHHHHHHCCCEECCCCCCCCCCCCHHHHCCCCEEEECCCCCEEECCCCCCCCCCCCCC
QKSRPQFMQLDLTSDAARAA
CCCCCCEEEEECCCHHHCCC
>Mature Secondary Structure 
AIGNFFSKRHVKGGGDATGSRAIGKTDPRRLSLLDDFESADLGWFWATDSESKLIYLSE
CCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCEEEEEEC
NAAAQFGCSADELIGKPLSELFILERGEEEKGEQSPQRPLPFLLRARNTISDLPVRISIG
CCCHHCCCCHHHHHCCCHHHHHHHCCCCHHHCCCCCCCCCHHHHHHCCHHHCCCEEEEEC
ESDDRKIWWSISGKPQLDGNGDLLGYRGSAKDITAVRQNQLEVGRMAQYDSLTGLANRHR
CCCCCEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTKRLTTTLTAYKAAKRSCALMMLDLDRFKQVNDTLGHPAGDELLKQVGQRLERIIGGNG
HHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
EIGRLGGDEFQVILPDIEDRGRLGEVAARVIQMISQPYSIDGARAIIGTSVGIAIAPYDG
CEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCC
IDTEELVGAADLALYAAKGGGRGQYRFYSSELKDGARHRREIEEDLRDALSMDQGLEMHY
CCHHHHHHHHHHEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QPLVDAKTHRVKCFEALIRWNHPERGWISPGDFIPVAEDTNQIGDLGEWVLRRVCTDASS
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCC
WPGDISVAVNVSAVQFGDPNLPQIVCKALKDSGLDPRRLELELTESVFIGDPNATHDMFV
CCCCEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECEEEECCCCCHHHHHH
ALKKLGVALALDDFGTGYSSLGYLKNAPFDKIKIDQSFVRGSTENDNNNSAIITAIVSLA
HHHHCCEEEEECCCCCCHHHCCHHCCCCCCEEECCHHHHCCCCCCCCCCHHHHHHHHHHH
GALNMTTVAEGVEAMDELELVRERGATYIQGFIFSKAIPQDVVLEKLESGDLAFEPNGPA
HHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCCCH
KHRSERKSVFRRIGVIHEDHRYDAVLRNLSKTGARIEGILNVPLGTQLVLDLGEGQLVVG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCEEHH
AVRRSVEAEQGIEFETPLISDGADGLCTRHRVSPYMLASAGMPLAALPPGHYPLTNRSDG
HHHHHHHHHCCCEECCCCCCCCCCCCHHHHCCCCEEEECCCCCEEECCCCCCCCCCCCCC
QKSRPQFMQLDLTSDAARAA
CCCCCCEEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]