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The map label for this gene is nuoG [H]

Identifier: 85374155

GI number: 85374155

Start: 1377792

End: 1379807

Strand: Reverse

Name: nuoG [H]

Synonym: ELI_06640

Alternate gene names: 85374155

Gene position: 1379807-1377792 (Counterclockwise)

Preceding gene: 85374156

Following gene: 85374154

Centisome position: 45.2

GC content: 63.34

Gene sequence:

>2016_bases
ATGCCTAAAGTCACCGTAGACGGACAGGAACTCGAGGTTCCGGACGGCGCAACCGTCCTCCAGGCCTGCGAGATGGCGGG
GAAGGAAATTCCGCGCTTCTGCTATCACGAACGGCTGAGCATCGCCGGCAATTGCCGCATGTGTCTGGTCGAGGTGAAGC
CGGGTCCACCCAAGCCGCAGGCGAGCTGCGCGCTGCCCGCGGCCGACGGGCAGGAAATCCGCACCGACAGCGAGATGGTC
AAGACCGCGCGCGAAGGCGTGATGGAATTCCTGCTCATCAACCACCCGCTCGACTGCCCGATCTGCGACCAGGGCGGCGA
ATGCGACCTTCAGGACCAGGCCGTTGCCTACGGTCGTGGCGGTTCGCGCTACGATATGAACAAGCGGGCGGTGACCGAGA
AATACATGGGCCCACTGATCAAAACGATCATGACCCGCTGCATCCACTGCACCCGCTGCGTGCGCTTTTCCGAAGAAATC
GCCGGCGTGGACGAAATCGGCGCGCTCTATCGCGGCGAGGACATGCAGATCACCACTTATCTGGAGCAGGCCGCCGAGCA
TGAGCTGTCGGCCAATGTGATCGACCTATGCCCGGTCGGCGCGCTGACCAGCCGGCCCTATGCTTTCGAAGCGCGTCCGT
GGGAATTGAAACGCACGCTCAGCATCGATGTGTCGGACGCTGTCGGCGCCAATATCACGCTCCATTCCAAAGGCCGCGAA
GTCATGCGCGCGCTCCCGCGCATCAATGACGACGTCAATGAAGAATGGGTCAGCGACAAGGGCCGCTACCAGGTTGATGG
CCTCATCAAACGGCGGCTCGACAAGGTCTTCATGCGCAAGCGCGGCAAGTTGCAGCCTGCGGGATGGGACGAGGCCTTCA
AGGCGATTGCGAAACAGCTCAAGGGCAACACCTCGAGCATCGCCGCCGTCGCAGGCGATCTGGTCGATTGCGAGACGATG
TTTGCGGCCAAGGCGCTGCTCAAGGCGTGCGGGTCGGACCTGCTCGAAGGCCGCCAGACCGGCATGGACTATGACGTGTC
GAACCTCGCGGCGGTCAATTTCAATTCGACGCTGGCCGGTATCGAGACCGCCGATGCGATCCTGATCGTCGGCAGCCACA
TCCGCTGGGAAGCGCCGCTGGTAAACGTGCGTTTGCGCAAGGCGGTGAAGCGCGGCGCCAAGGTGTTCGTGATCGGGCCG
GAGTGGGAGACCACTTTCCCAGCGACGTTCCTCGGAAGTGACCTCGCGGTGCTGTCGGACCTGCCGAGCGATCTGGTCGA
TAACTTCAAGGGCGCTGAGCGTTCCGCCATCATCATGGGCGGCGCAGCCTTGGCCAAGGGCGCTCTTGGCGCAGGTCTTG
CCGCCGCCGATACGCTCGGCTGCATCAAGGACGGCTGGAACGGCTTCAACGTGCTGCACTTCTCCGCCGCGCGCATGGGC
GGGCTGATGCTCGGCTATGCGCAGAAGGGCGGGGTGAAGGACATCGCCAAGGCCGCGCCCAAGGTTCTGCTGGCGCTAGG
CGCGGACGAGATGGATTTCGAACCGTTCGCCGACAGCCTCAAGGTCTATATCGGCCACCACGGCGACAAGGGCGCGCATG
CGGCGGATATCATCCTGCCCGCGGCGAGCTATGCCGAGAAAGACGGCACCTACGTCAATACCGAAGGCCGCGTCCAATAT
GCCGAGAAAGCCGTCTTCGCGCCGGGCGATGCCCGCGAAGACTGGACCATCCTGCGCGCGCTGGCCGATGCGATTGGCGT
TGAGGTCGGCTTTGACAGCTTCGACCAGTTGCAGAGCGCCATGATCGCCGAAGTACCGGCCTTGGGTGAAGAAGGTCTCG
CCGATCTCGGCAAGCTGCCCAAGGCGGACAGCAAGGCCAAGGCCGAAGGCGTTATCGAAGCCTATCCGATCAAGGATTTC
TACCTCACCAACCCCATCGCCCGCGCCAGCGCGGTGATGCAGCAATGCTCGGCCGAGCTGCTGCATGGCGATGAACTCGC
GGAGGCGGCGGAATGA

Upstream 100 bases:

>100_bases
ACCTCGCGCGGCGCGCCGGTCGAAGCCTCCCCGCTCGCGATGCGCGCCATGCTCGCCACCGCTTCTTTCCGCCTGCTTGC
AGCCCAGAAGGCCCAAACCG

Downstream 100 bases:

>100_bases
GCGTCGTTCTGACTATCCTCGCCGCTGTGATTGTGAGCGCTTCGGCCATCGCTGCCATCGTGCTGGTTTCGAAGAAGGTA
TCCGACAGGAAAATGGACCG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MPKVTVDGQELEVPDGATVLQACEMAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQASCALPAADGQEIRTDSEMV
KTAREGVMEFLLINHPLDCPICDQGGECDLQDQAVAYGRGGSRYDMNKRAVTEKYMGPLIKTIMTRCIHCTRCVRFSEEI
AGVDEIGALYRGEDMQITTYLEQAAEHELSANVIDLCPVGALTSRPYAFEARPWELKRTLSIDVSDAVGANITLHSKGRE
VMRALPRINDDVNEEWVSDKGRYQVDGLIKRRLDKVFMRKRGKLQPAGWDEAFKAIAKQLKGNTSSIAAVAGDLVDCETM
FAAKALLKACGSDLLEGRQTGMDYDVSNLAAVNFNSTLAGIETADAILIVGSHIRWEAPLVNVRLRKAVKRGAKVFVIGP
EWETTFPATFLGSDLAVLSDLPSDLVDNFKGAERSAIIMGGAALAKGALGAGLAAADTLGCIKDGWNGFNVLHFSAARMG
GLMLGYAQKGGVKDIAKAAPKVLLALGADEMDFEPFADSLKVYIGHHGDKGAHAADIILPAASYAEKDGTYVNTEGRVQY
AEKAVFAPGDAREDWTILRALADAIGVEVGFDSFDQLQSAMIAEVPALGEEGLADLGKLPKADSKAKAEGVIEAYPIKDF
YLTNPIARASAVMQQCSAELLHGDELAEAAE

Sequences:

>Translated_671_residues
MPKVTVDGQELEVPDGATVLQACEMAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQASCALPAADGQEIRTDSEMV
KTAREGVMEFLLINHPLDCPICDQGGECDLQDQAVAYGRGGSRYDMNKRAVTEKYMGPLIKTIMTRCIHCTRCVRFSEEI
AGVDEIGALYRGEDMQITTYLEQAAEHELSANVIDLCPVGALTSRPYAFEARPWELKRTLSIDVSDAVGANITLHSKGRE
VMRALPRINDDVNEEWVSDKGRYQVDGLIKRRLDKVFMRKRGKLQPAGWDEAFKAIAKQLKGNTSSIAAVAGDLVDCETM
FAAKALLKACGSDLLEGRQTGMDYDVSNLAAVNFNSTLAGIETADAILIVGSHIRWEAPLVNVRLRKAVKRGAKVFVIGP
EWETTFPATFLGSDLAVLSDLPSDLVDNFKGAERSAIIMGGAALAKGALGAGLAAADTLGCIKDGWNGFNVLHFSAARMG
GLMLGYAQKGGVKDIAKAAPKVLLALGADEMDFEPFADSLKVYIGHHGDKGAHAADIILPAASYAEKDGTYVNTEGRVQY
AEKAVFAPGDAREDWTILRALADAIGVEVGFDSFDQLQSAMIAEVPALGEEGLADLGKLPKADSKAKAEGVIEAYPIKDF
YLTNPIARASAVMQQCSAELLHGDELAEAAE
>Mature_670_residues
PKVTVDGQELEVPDGATVLQACEMAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQASCALPAADGQEIRTDSEMVK
TAREGVMEFLLINHPLDCPICDQGGECDLQDQAVAYGRGGSRYDMNKRAVTEKYMGPLIKTIMTRCIHCTRCVRFSEEIA
GVDEIGALYRGEDMQITTYLEQAAEHELSANVIDLCPVGALTSRPYAFEARPWELKRTLSIDVSDAVGANITLHSKGREV
MRALPRINDDVNEEWVSDKGRYQVDGLIKRRLDKVFMRKRGKLQPAGWDEAFKAIAKQLKGNTSSIAAVAGDLVDCETMF
AAKALLKACGSDLLEGRQTGMDYDVSNLAAVNFNSTLAGIETADAILIVGSHIRWEAPLVNVRLRKAVKRGAKVFVIGPE
WETTFPATFLGSDLAVLSDLPSDLVDNFKGAERSAIIMGGAALAKGALGAGLAAADTLGCIKDGWNGFNVLHFSAARMGG
LMLGYAQKGGVKDIAKAAPKVLLALGADEMDFEPFADSLKVYIGHHGDKGAHAADIILPAASYAEKDGTYVNTEGRVQYA
EKAVFAPGDAREDWTILRALADAIGVEVGFDSFDQLQSAMIAEVPALGEEGLADLGKLPKADSKAKAEGVIEAYPIKDFY
LTNPIARASAVMQQCSAELLHGDELAEAAE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=699, Percent_Identity=46.20886981402, Blast_Score=589, Evalue=1e-168,
Organism=Escherichia coli, GI145693161, Length=691, Percent_Identity=26.7727930535456, Blast_Score=211, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17565758, Length=685, Percent_Identity=45.4014598540146, Blast_Score=538, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI32566231, Length=580, Percent_Identity=48.1034482758621, Blast_Score=500, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=59.1269841269841, Blast_Score=324, Evalue=7e-89,
Organism=Drosophila melanogaster, GI24640559, Length=674, Percent_Identity=49.406528189911, Blast_Score=593, Evalue=1e-169,
Organism=Drosophila melanogaster, GI24640557, Length=674, Percent_Identity=49.406528189911, Blast_Score=593, Evalue=1e-169,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 72192; Mature: 72061

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVTVDGQELEVPDGATVLQACEMAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQ
CCCEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
ASCALPAADGQEIRTDSEMVKTAREGVMEFLLINHPLDCPICDQGGECDLQDQAVAYGRG
CCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCC
GSRYDMNKRAVTEKYMGPLIKTIMTRCIHCTRCVRFSEEIAGVDEIGALYRGEDMQITTY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHH
LEQAAEHELSANVIDLCPVGALTSRPYAFEARPWELKRTLSIDVSDAVGANITLHSKGRE
HHHHHHHHHCCCEEHCCCCCCCCCCCCEECCCCCEEEEEEEEECHHCCCCCEEEECCCHH
VMRALPRINDDVNEEWVSDKGRYQVDGLIKRRLDKVFMRKRGKLQPAGWDEAFKAIAKQL
HHHHHHCCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KGNTSSIAAVAGDLVDCETMFAAKALLKACGSDLLEGRQTGMDYDVSNLAAVNFNSTLAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEECCCCCCCC
IETADAILIVGSHIRWEAPLVNVRLRKAVKRGAKVFVIGPEWETTFPATFLGSDLAVLSD
CCCCCEEEEEECCEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCHHHHHH
LPSDLVDNFKGAERSAIIMGGAALAKGALGAGLAAADTLGCIKDGWNGFNVLHFSAARMG
CCHHHHHHCCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHC
GLMLGYAQKGGVKDIAKAAPKVLLALGADEMDFEPFADSLKVYIGHHGDKGAHAADIILP
CEEEEECCCCCHHHHHHHCCCEEEEECCCCCCCCHHHCCEEEEEECCCCCCCCHHHEEEC
AASYAEKDGTYVNTEGRVQYAEKAVFAPGDAREDWTILRALADAIGVEVGFDSFDQLQSA
CHHHHCCCCCEECCCCCEEHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
MIAEVPALGEEGLADLGKLPKADSKAKAEGVIEAYPIKDFYLTNPIARASAVMQQCSAEL
HHHHCCCCCCCCHHHHHCCCCCCCCHHHCCCEEEECCCHHHHCCHHHHHHHHHHHHHHHH
LHGDELAEAAE
HCCHHHHHHCC
>Mature Secondary Structure 
PKVTVDGQELEVPDGATVLQACEMAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQ
CCEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
ASCALPAADGQEIRTDSEMVKTAREGVMEFLLINHPLDCPICDQGGECDLQDQAVAYGRG
CCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCC
GSRYDMNKRAVTEKYMGPLIKTIMTRCIHCTRCVRFSEEIAGVDEIGALYRGEDMQITTY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHH
LEQAAEHELSANVIDLCPVGALTSRPYAFEARPWELKRTLSIDVSDAVGANITLHSKGRE
HHHHHHHHHCCCEEHCCCCCCCCCCCCEECCCCCEEEEEEEEECHHCCCCCEEEECCCHH
VMRALPRINDDVNEEWVSDKGRYQVDGLIKRRLDKVFMRKRGKLQPAGWDEAFKAIAKQL
HHHHHHCCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KGNTSSIAAVAGDLVDCETMFAAKALLKACGSDLLEGRQTGMDYDVSNLAAVNFNSTLAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEECCCCCCCC
IETADAILIVGSHIRWEAPLVNVRLRKAVKRGAKVFVIGPEWETTFPATFLGSDLAVLSD
CCCCCEEEEEECCEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCHHHHHH
LPSDLVDNFKGAERSAIIMGGAALAKGALGAGLAAADTLGCIKDGWNGFNVLHFSAARMG
CCHHHHHHCCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHC
GLMLGYAQKGGVKDIAKAAPKVLLALGADEMDFEPFADSLKVYIGHHGDKGAHAADIILP
CEEEEECCCCCHHHHHHHCCCEEEEECCCCCCCCHHHCCEEEEEECCCCCCCCHHHEEEC
AASYAEKDGTYVNTEGRVQYAEKAVFAPGDAREDWTILRALADAIGVEVGFDSFDQLQSA
CHHHHCCCCCEECCCCCEEHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
MIAEVPALGEEGLADLGKLPKADSKAKAEGVIEAYPIKDFYLTNPIARASAVMQQCSAEL
HHHHCCCCCCCCHHHHHCCCCCCCCHHHCCCEEEECCCHHHHCCHHHHHHHHHHHHHHHH
LHGDELAEAAE
HCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA