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The map label for this gene is 85374035

Identifier: 85374035

GI number: 85374035

Start: 1248961

End: 1250124

Strand: Reverse

Name: 85374035

Synonym: ELI_06040

Alternate gene names: NA

Gene position: 1250124-1248961 (Counterclockwise)

Preceding gene: 85374036

Following gene: 85374034

Centisome position: 40.96

GC content: 60.91

Gene sequence:

>1164_bases
ATGGAGCTTAAAGACTACGGTTTGAGCCGCGAGCGCGGCTATCTTTCGCATTACGAGATCGACGAGATCACGCTGCCCGC
CGAACTTGCCGACATCGTCGGCGCGGCAAACAACCTTTCCGGACTGCTTTCGACCGGCAGGGTCCGCCACTGGCTCGACC
GGTTGCCCGATCCCGAAATCGAGGAATGGGCTCGTGAAGCCCCGGAAGCGCAGGTCCGCACCGCGATGGTGCATCTCTCC
TTCCTCGTGCAGGCCTACGTTTGGGGAGAAGACGTTCCGTCACAGCATTTGCCCGCCAATCTTGCCCGCCCCATCGTCGC
CGTGGCCGATCGTCTCGGACAATCGCCGCTGCTGCCGTATTCGGGCTATGTGCTCGACAATTGGGCGCGTCTCGACAAAT
CGGGCCCTATCTCGCTCGACAACATCTACATGTACCAGAACTTCGTCGGGGGAGACGACGAGAACTGGTTCGTGATGATT
CACGTCGCAATAGAGGCCGAAGCCGGCGTGCTTCTCGACAATGCGGCGAAGCTGGTGACCGCCGCGAAGACCGGAGATGA
ATCAGAGGCAGAGCGGCTCCTCGTTGAAATGGACGCGGCATGGGAGCGTATCTACGCCCACTTCGCGCGCATGCCCGAGC
GCTGCGATCCCTACATCTATTTTCATCGCGTGCGGCCATACATCCACGGCTGGGCGAACAATCCGGCGCTGAAAGGCGGC
GGCCTGATTTACGAAGGCGTCGACCAGCTTGGCGGAAAACCGCAGGCGCTGCGCGGGCAGACCGGTTCGCAATCCAGCAT
CGTCCCAGCGATGGATGCCGTCTTCCAGGTCGGCCACAGCGACGATCCGCTGAAGAGCTTCCTCGACGAACTGCATCGCT
ACCGCCCGGTCCAGCACCGCAGGTTTATCGAGGATCTGACAGCGCAGTCGACATTGCGGAGCTTTGTCGAAGGTTCGTCG
AGCCAAAGCCTGAAAGACGCGTTCAACGCCTGCCTCAACCAATCTGCGCGCTTCCGCACGCGGCATCTCGAGTATGCGGC
GAGCTACATCAACAAGCAGGCAGGCAGCATCGCGGGCAATGACCCGGACGTTGGAACAGGTGGCACACCGTTCATGAGAT
ACCTGAAGAAGCACCGCGACGAGAACGCGGCGCAATTGGTGTGA

Upstream 100 bases:

>100_bases
TACCGCATAAAGTCTGTACCCGCTTGAGCGAAAAGGTTGCATTTGATACCGCTTTGGCGTCCGGGCGGCCCAACCCGCGC
CCGGCCAAAGAGTCTCAACA

Downstream 100 bases:

>100_bases
TTTACTGTTTGGCAGGAAAAACTGCGCATTATCCAGGAAATGGAGCGCATTTATTCTGCCAGAAAAGATTTCGCCGTCGC
TCGCAGTGAGTTTATCGACG

Product: hypothetical protein

Products: N-formylkynurenine

Alternate protein names: Indoleamine-Pyrrole 2 3-Dioxygenase; Dioxygenanse

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MELKDYGLSRERGYLSHYEIDEITLPAELADIVGAANNLSGLLSTGRVRHWLDRLPDPEIEEWAREAPEAQVRTAMVHLS
FLVQAYVWGEDVPSQHLPANLARPIVAVADRLGQSPLLPYSGYVLDNWARLDKSGPISLDNIYMYQNFVGGDDENWFVMI
HVAIEAEAGVLLDNAAKLVTAAKTGDESEAERLLVEMDAAWERIYAHFARMPERCDPYIYFHRVRPYIHGWANNPALKGG
GLIYEGVDQLGGKPQALRGQTGSQSSIVPAMDAVFQVGHSDDPLKSFLDELHRYRPVQHRRFIEDLTAQSTLRSFVEGSS
SQSLKDAFNACLNQSARFRTRHLEYAASYINKQAGSIAGNDPDVGTGGTPFMRYLKKHRDENAAQLV

Sequences:

>Translated_387_residues
MELKDYGLSRERGYLSHYEIDEITLPAELADIVGAANNLSGLLSTGRVRHWLDRLPDPEIEEWAREAPEAQVRTAMVHLS
FLVQAYVWGEDVPSQHLPANLARPIVAVADRLGQSPLLPYSGYVLDNWARLDKSGPISLDNIYMYQNFVGGDDENWFVMI
HVAIEAEAGVLLDNAAKLVTAAKTGDESEAERLLVEMDAAWERIYAHFARMPERCDPYIYFHRVRPYIHGWANNPALKGG
GLIYEGVDQLGGKPQALRGQTGSQSSIVPAMDAVFQVGHSDDPLKSFLDELHRYRPVQHRRFIEDLTAQSTLRSFVEGSS
SQSLKDAFNACLNQSARFRTRHLEYAASYINKQAGSIAGNDPDVGTGGTPFMRYLKKHRDENAAQLV
>Mature_387_residues
MELKDYGLSRERGYLSHYEIDEITLPAELADIVGAANNLSGLLSTGRVRHWLDRLPDPEIEEWAREAPEAQVRTAMVHLS
FLVQAYVWGEDVPSQHLPANLARPIVAVADRLGQSPLLPYSGYVLDNWARLDKSGPISLDNIYMYQNFVGGDDENWFVMI
HVAIEAEAGVLLDNAAKLVTAAKTGDESEAERLLVEMDAAWERIYAHFARMPERCDPYIYFHRVRPYIHGWANNPALKGG
GLIYEGVDQLGGKPQALRGQTGSQSSIVPAMDAVFQVGHSDDPLKSFLDELHRYRPVQHRRFIEDLTAQSTLRSFVEGSS
SQSLKDAFNACLNQSARFRTRHLEYAASYINKQAGSIAGNDPDVGTGGTPFMRYLKKHRDENAAQLV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI148539554, Length=402, Percent_Identity=29.1044776119403, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4504577, Length=402, Percent_Identity=26.3681592039801, Blast_Score=150, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6322538, Length=356, Percent_Identity=28.3707865168539, Blast_Score=165, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.13.11.42

Molecular weight: Translated: 43254; Mature: 43254

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKDYGLSRERGYLSHYEIDEITLPAELADIVGAANNLSGLLSTGRVRHWLDRLPDPEI
CCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCH
EEWAREAPEAQVRTAMVHLSFLVQAYVWGEDVPSQHLPANLARPIVAVADRLGQSPLLPY
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
SGYVLDNWARLDKSGPISLDNIYMYQNFVGGDDENWFVMIHVAIEAEAGVLLDNAAKLVT
CCCEEHHHHHCCCCCCCCHHHEEEEHHHCCCCCCCEEEEEEEEEECCCCEEEHHHHHHHH
AAKTGDESEAERLLVEMDAAWERIYAHFARMPERCDPYIYFHRVRPYIHGWANNPALKGG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCEEEEEECCHHHCCCCCCCCCCCC
GLIYEGVDQLGGKPQALRGQTGSQSSIVPAMDAVFQVGHSDDPLKSFLDELHRYRPVQHR
CCHHHCHHHHCCCCCHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHH
RFIEDLTAQSTLRSFVEGSSSQSLKDAFNACLNQSARFRTRHLEYAASYINKQAGSIAGN
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
DPDVGTGGTPFMRYLKKHRDENAAQLV
CCCCCCCCHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MELKDYGLSRERGYLSHYEIDEITLPAELADIVGAANNLSGLLSTGRVRHWLDRLPDPEI
CCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCH
EEWAREAPEAQVRTAMVHLSFLVQAYVWGEDVPSQHLPANLARPIVAVADRLGQSPLLPY
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
SGYVLDNWARLDKSGPISLDNIYMYQNFVGGDDENWFVMIHVAIEAEAGVLLDNAAKLVT
CCCEEHHHHHCCCCCCCCHHHEEEEHHHCCCCCCCEEEEEEEEEECCCCEEEHHHHHHHH
AAKTGDESEAERLLVEMDAAWERIYAHFARMPERCDPYIYFHRVRPYIHGWANNPALKGG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCEEEEEECCHHHCCCCCCCCCCCC
GLIYEGVDQLGGKPQALRGQTGSQSSIVPAMDAVFQVGHSDDPLKSFLDELHRYRPVQHR
CCHHHCHHHHCCCCCHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHH
RFIEDLTAQSTLRSFVEGSSSQSLKDAFNACLNQSARFRTRHLEYAASYINKQAGSIAGN
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
DPDVGTGGTPFMRYLKKHRDENAAQLV
CCCCCCCCHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan; O2

Specific reaction: L-tryptophan + O2 = N-formylkynurenine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA