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The map label for this gene is xerC [H]

Identifier: 85374026

GI number: 85374026

Start: 1240740

End: 1241534

Strand: Reverse

Name: xerC [H]

Synonym: ELI_05995

Alternate gene names: 85374026

Gene position: 1241534-1240740 (Counterclockwise)

Preceding gene: 85374027

Following gene: 85374022

Centisome position: 40.67

GC content: 63.77

Gene sequence:

>795_bases
ATGCTCGACTCCCTTGGCTCCGAAAACTGGGAGGATGTCGCGGCGACCAACGCAGTAACACTACGTCGTCATCTGGCGGC
GCGCCGCGCCGAGGGACTGGCTAATACGTCGGCAGCACGTGAACTTTCCGCTCTGAAGGCCTTCATTGCCTACGCCCGCA
GCGAGACGGGGGACGCCGAAGCAACTGCGCCGCGCCTTCGAGGCCCGCGGATCAAGAAGGGCTTGCCCCGGCCCGTCACC
CCCGACGAGGCGATCAACCTTGCGGATACGGTCGATGCCAGCGCGGCGGACGACTGGATCGGCAAGCGCGATCGGGCGGT
TTTGCTGCTGCTCTACGGCGCGGGATTGCGGATTGCCGAGGCGCTGTCGCTGACCGGGAAAGCGGTGCCGCTAGGAGAAA
GCCTTCAGGTCACCGGCAAAGGCGGTAAGCAACGCGTGGTGCCCATACTGCCACTGATTGGCGACGCAGTGGCGGATTAT
GCGAAAACCTGTCCATGGCCGATCGAGCCGAAAGGACCTCTTTTCAGAGGCGCGAAAGGTGGCCCCTTGTCACAGGGTAT
GATCCAGAAAACGACCGCGCGCGCGAGGCGCGCTCTTGGCCTGCCGGACACGGCCACGCCGCATGCGCTGAGGCACAGTT
TTGCCACTCATTTGCTGGGTGCAGGGGCCGATCTCCGGAGCCTGCAGGAATTGCTCGGCCACGCCAGTCTCGGTTCGACG
CAGATCTATACCAAGGTGGATGCGGCCACCCTGCTTGACACCTATCGCAAAGCGCATCCGCGCGAGAAGGATTAG

Upstream 100 bases:

>100_bases
GAGCGCCGCTGAATTACTCGCGCAATGGCACACTTATCTCGCCGACGAGAGACGACGTTCGCCCCATACCGTGCGGGCCT
ATCACACGGCGGCGCGCCGA

Downstream 100 bases:

>100_bases
CTACATCGCCGCGTGGCGCGCTTCGATCGCGTCCCAGATTTTTGCTGGCGTGTCGGTGCCGTTGAACTTGTCAATCGCGA
CGATGCCGGTGGGCGAAGTG

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MLDSLGSENWEDVAATNAVTLRRHLAARRAEGLANTSAARELSALKAFIAYARSETGDAEATAPRLRGPRIKKGLPRPVT
PDEAINLADTVDASAADDWIGKRDRAVLLLLYGAGLRIAEALSLTGKAVPLGESLQVTGKGGKQRVVPILPLIGDAVADY
AKTCPWPIEPKGPLFRGAKGGPLSQGMIQKTTARARRALGLPDTATPHALRHSFATHLLGAGADLRSLQELLGHASLGST
QIYTKVDAATLLDTYRKAHPREKD

Sequences:

>Translated_264_residues
MLDSLGSENWEDVAATNAVTLRRHLAARRAEGLANTSAARELSALKAFIAYARSETGDAEATAPRLRGPRIKKGLPRPVT
PDEAINLADTVDASAADDWIGKRDRAVLLLLYGAGLRIAEALSLTGKAVPLGESLQVTGKGGKQRVVPILPLIGDAVADY
AKTCPWPIEPKGPLFRGAKGGPLSQGMIQKTTARARRALGLPDTATPHALRHSFATHLLGAGADLRSLQELLGHASLGST
QIYTKVDAATLLDTYRKAHPREKD
>Mature_264_residues
MLDSLGSENWEDVAATNAVTLRRHLAARRAEGLANTSAARELSALKAFIAYARSETGDAEATAPRLRGPRIKKGLPRPVT
PDEAINLADTVDASAADDWIGKRDRAVLLLLYGAGLRIAEALSLTGKAVPLGESLQVTGKGGKQRVVPILPLIGDAVADY
AKTCPWPIEPKGPLFRGAKGGPLSQGMIQKTTARARRALGLPDTATPHALRHSFATHLLGAGADLRSLQELLGHASLGST
QIYTKVDAATLLDTYRKAHPREKD

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=261, Percent_Identity=36.7816091954023, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789261, Length=246, Percent_Identity=32.520325203252, Blast_Score=116, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 28013; Mature: 28013

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSLGSENWEDVAATNAVTLRRHLAARRAEGLANTSAARELSALKAFIAYARSETGDAE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ATAPRLRGPRIKKGLPRPVTPDEAINLADTVDASAADDWIGKRDRAVLLLLYGAGLRIAE
CCCCCCCCCHHHCCCCCCCCCHHHHCHHHHCCCCHHHHHHCCCCCEEEEEEECCCHHHHH
ALSLTGKAVPLGESLQVTGKGGKQRVVPILPLIGDAVADYAKTCPWPIEPKGPLFRGAKG
HHHHCCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GPLSQGMIQKTTARARRALGLPDTATPHALRHSFATHLLGAGADLRSLQELLGHASLGST
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
QIYTKVDAATLLDTYRKAHPREKD
EEEHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLDSLGSENWEDVAATNAVTLRRHLAARRAEGLANTSAARELSALKAFIAYARSETGDAE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ATAPRLRGPRIKKGLPRPVTPDEAINLADTVDASAADDWIGKRDRAVLLLLYGAGLRIAE
CCCCCCCCCHHHCCCCCCCCCHHHHCHHHHCCCCHHHHHHCCCCCEEEEEEECCCHHHHH
ALSLTGKAVPLGESLQVTGKGGKQRVVPILPLIGDAVADYAKTCPWPIEPKGPLFRGAKG
HHHHCCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GPLSQGMIQKTTARARRALGLPDTATPHALRHSFATHLLGAGADLRSLQELLGHASLGST
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
QIYTKVDAATLLDTYRKAHPREKD
EEEHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]