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The map label for this gene is yusZ [H]

Identifier: 85373991

GI number: 85373991

Start: 1201932

End: 1202927

Strand: Reverse

Name: yusZ [H]

Synonym: ELI_05820

Alternate gene names: 85373991

Gene position: 1202927-1201932 (Counterclockwise)

Preceding gene: 85373992

Following gene: 85373990

Centisome position: 39.41

GC content: 64.26

Gene sequence:

>996_bases
ATGACCGCCCTCACCCGCCGCACCCTGCTCGCCAGTGCCGCTGCAACCGGCGCGATCGCTGCCACCGCCGGCTATGCGCA
ACAAGACAAGGTCGAAGCGACGCCGGACCTCGTCGGCACAAGTGTGATTATCACCGGTTGCTCCAGCGGCTTCGGGCGGC
TGAGCGCCGAACACTTCGCGCGGCTCGGTGCGAAAGTCTTCGCCACCATGCGCAACCTCCCCCGTCCGGAGGCCGATGAA
CTGAAGGCAGTCGCCGAAGCGGACGATCTCGACATCCATATCCTCGAGCTCGACGTATTGCTCGACGAGCACACCCAAGG
CGCGGTCGGAGAAGCCGAGCGGATCAATGGCGGGCCGATCGACGTGCTGGTCAACAATGCCGGGATCGGCGTGTCCGGCC
CGATAGAAGTGCAGGACATGGAAGCCACCAAGCTGATATTCGACACAAATGTCTATGGCTGCCACCGCATGGTTCGCGCG
GTCCTGCCCGGCATGCGCAAGAAAGGCGGCGGCCAGATCTACCAGATCAGCAGCCAGCTGGGCCGCGTTATCGTGCCCTA
CAGCGGGCACTATTCGCCGACTAAGTTTGCGCTCGAAGCTATGAGCGAGGCGCTCGCCTACGAGTTGGTGCCGCACCATA
TCGACGTGACCATCATCGAGCCGGGCGGCTATCCGACCGAGGTCTGGGTCAACCGCAATATCCACACCAAGGCGCTGAAA
GAGCGAGCATCCAAAGTCCACACTTCGGGCTATCCGCAAGTCGTGGCCCGCATGGGCGAGGAAGACGGTTCAGGCCGCGA
CGCCGATCCGATGGACATTCCCCGCGCCATCGCCGCGATTATGGCCATGCCTGCCGGCACCCGGCCCCTGCGTAAGCCGG
TCAGCGGCGGAAACATCCCGCAGATCCGCATCAACGACGTGACGGCGGATACCCAGGTCGCCTGGCTGGGCGAGAGCCGG
CTGGGGCCGATGATTACCGCCGTTCACAGGCGCTAG

Upstream 100 bases:

>100_bases
CGCGAACCGAGGGCTTGCTGCGGGGCACGGATGCGCGCATCTTGCGGTTCGAGACACCGCAGGCACTCGATGCCTGGCTG
GCCGAATTGGAGAGAGATAG

Downstream 100 bases:

>100_bases
CCATCGGGCGGGCATCCCGCTAAGGGGCGCGCCACACAGTTTTCCGGAGTATGAGATGGGTTTCCGTTGCGGGATCGTCG
GCCTGCCGAATGTCGGCAAG

Product: short-chain dehydrogenase/reductase family protein

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTALTRRTLLASAAATGAIAATAGYAQQDKVEATPDLVGTSVIITGCSSGFGRLSAEHFARLGAKVFATMRNLPRPEADE
LKAVAEADDLDIHILELDVLLDEHTQGAVGEAERINGGPIDVLVNNAGIGVSGPIEVQDMEATKLIFDTNVYGCHRMVRA
VLPGMRKKGGGQIYQISSQLGRVIVPYSGHYSPTKFALEAMSEALAYELVPHHIDVTIIEPGGYPTEVWVNRNIHTKALK
ERASKVHTSGYPQVVARMGEEDGSGRDADPMDIPRAIAAIMAMPAGTRPLRKPVSGGNIPQIRINDVTADTQVAWLGESR
LGPMITAVHRR

Sequences:

>Translated_331_residues
MTALTRRTLLASAAATGAIAATAGYAQQDKVEATPDLVGTSVIITGCSSGFGRLSAEHFARLGAKVFATMRNLPRPEADE
LKAVAEADDLDIHILELDVLLDEHTQGAVGEAERINGGPIDVLVNNAGIGVSGPIEVQDMEATKLIFDTNVYGCHRMVRA
VLPGMRKKGGGQIYQISSQLGRVIVPYSGHYSPTKFALEAMSEALAYELVPHHIDVTIIEPGGYPTEVWVNRNIHTKALK
ERASKVHTSGYPQVVARMGEEDGSGRDADPMDIPRAIAAIMAMPAGTRPLRKPVSGGNIPQIRINDVTADTQVAWLGESR
LGPMITAVHRR
>Mature_330_residues
TALTRRTLLASAAATGAIAATAGYAQQDKVEATPDLVGTSVIITGCSSGFGRLSAEHFARLGAKVFATMRNLPRPEADEL
KAVAEADDLDIHILELDVLLDEHTQGAVGEAERINGGPIDVLVNNAGIGVSGPIEVQDMEATKLIFDTNVYGCHRMVRAV
LPGMRKKGGGQIYQISSQLGRVIVPYSGHYSPTKFALEAMSEALAYELVPHHIDVTIIEPGGYPTEVWVNRNIHTKALKE
RASKVHTSGYPQVVARMGEEDGSGRDADPMDIPRAIAAIMAMPAGTRPLRKPVSGGNIPQIRINDVTADTQVAWLGESRL
GPMITAVHRR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=40.5263157894737, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI223718074, Length=217, Percent_Identity=35.0230414746544, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI44680136, Length=194, Percent_Identity=32.9896907216495, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI44680133, Length=194, Percent_Identity=32.9896907216495, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI17738292, Length=194, Percent_Identity=32.9896907216495, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=35.3846153846154, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4503817, Length=230, Percent_Identity=29.1304347826087, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI22507405, Length=213, Percent_Identity=30.9859154929577, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI150247226, Length=191, Percent_Identity=34.5549738219895, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI119392083, Length=190, Percent_Identity=29.4736842105263, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=26.5625, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI50726952, Length=189, Percent_Identity=32.8042328042328, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI7705925, Length=186, Percent_Identity=30.6451612903226, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI157739938, Length=199, Percent_Identity=26.6331658291457, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI19743808, Length=221, Percent_Identity=31.2217194570136, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI142976729, Length=177, Percent_Identity=29.3785310734463, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI226371731, Length=201, Percent_Identity=26.3681592039801, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1786701, Length=200, Percent_Identity=33, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787820, Length=192, Percent_Identity=36.4583333333333, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787335, Length=195, Percent_Identity=31.2820512820513, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790717, Length=217, Percent_Identity=30.8755760368664, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787526, Length=209, Percent_Identity=29.6650717703349, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082160, Length=196, Percent_Identity=28.0612244897959, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788459, Length=186, Percent_Identity=31.1827956989247, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=192, Percent_Identity=30.7291666666667, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17557780, Length=230, Percent_Identity=29.5652173913043, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534660, Length=210, Percent_Identity=30.952380952381, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193210355, Length=230, Percent_Identity=30, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=238, Percent_Identity=29.8319327731092, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=238, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=207, Percent_Identity=32.3671497584541, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=207, Percent_Identity=32.3671497584541, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=209, Percent_Identity=29.1866028708134, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=189, Percent_Identity=31.2169312169312, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=243, Percent_Identity=27.5720164609054, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=188, Percent_Identity=30.8510638297872, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=230, Percent_Identity=29.1304347826087, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=30.3030303030303, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=29.7297297297297, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356301, Length=189, Percent_Identity=31.2169312169312, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI23397609, Length=260, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281364892, Length=178, Percent_Identity=35.3932584269663, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643142, Length=188, Percent_Identity=30.3191489361702, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357041, Length=224, Percent_Identity=30.8035714285714, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24580925, Length=199, Percent_Identity=31.6582914572864, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24651139, Length=212, Percent_Identity=27.3584905660377, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24644339, Length=265, Percent_Identity=26.4150943396226, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45553409, Length=208, Percent_Identity=27.4038461538462, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24647948, Length=208, Percent_Identity=27.4038461538462, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24647946, Length=208, Percent_Identity=27.4038461538462, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35400; Mature: 35269

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALTRRTLLASAAATGAIAATAGYAQQDKVEATPDLVGTSVIITGCSSGFGRLSAEHFA
CCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHCCEEEEEECCCCCCCCCHHHHH
RLGAKVFATMRNLPRPEADELKAVAEADDLDIHILELDVLLDEHTQGAVGEAERINGGPI
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCHHHCCCCCE
DVLVNNAGIGVSGPIEVQDMEATKLIFDTNVYGCHRMVRAVLPGMRKKGGGQIYQISSQL
EEEEECCCCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHCCCHHCCCCCEEEEECHHC
GRVIVPYSGHYSPTKFALEAMSEALAYELVPHHIDVTIIEPGGYPTEVWVNRNIHTKALK
CCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCHHHHHH
ERASKVHTSGYPQVVARMGEEDGSGRDADPMDIPRAIAAIMAMPAGTRPLRKPVSGGNIP
HHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCC
QIRINDVTADTQVAWLGESRLGPMITAVHRR
EEEEECCCCCCEEEEECCCCCCHHHHHHCCC
>Mature Secondary Structure 
TALTRRTLLASAAATGAIAATAGYAQQDKVEATPDLVGTSVIITGCSSGFGRLSAEHFA
CCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHCCEEEEEECCCCCCCCCHHHHH
RLGAKVFATMRNLPRPEADELKAVAEADDLDIHILELDVLLDEHTQGAVGEAERINGGPI
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCHHHCCCCCE
DVLVNNAGIGVSGPIEVQDMEATKLIFDTNVYGCHRMVRAVLPGMRKKGGGQIYQISSQL
EEEEECCCCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHCCCHHCCCCCEEEEECHHC
GRVIVPYSGHYSPTKFALEAMSEALAYELVPHHIDVTIIEPGGYPTEVWVNRNIHTKALK
CCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCHHHHHH
ERASKVHTSGYPQVVARMGEEDGSGRDADPMDIPRAIAAIMAMPAGTRPLRKPVSGGNIP
HHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCC
QIRINDVTADTQVAWLGESRLGPMITAVHRR
EEEEECCCCCCEEEEECCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]