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The map label for this gene is nrdR

Identifier: 85373955

GI number: 85373955

Start: 1167248

End: 1167709

Strand: Reverse

Name: nrdR

Synonym: ELI_05640

Alternate gene names: 85373955

Gene position: 1167709-1167248 (Counterclockwise)

Preceding gene: 85373956

Following gene: 85373954

Centisome position: 38.26

GC content: 61.69

Gene sequence:

>462_bases
ATGCGCTGCCCATTCTGTGCGCATGACGACAGCCAGGTAAAAGACTCACGCCCGGCTGAAGACAACGCCGCTATCCGCCG
TCGCCGCCAATGTTCCAAATGCGGAGCTCGCTTCACGACCTTCGAGCGCGTGCAATTGCGCGATGTGACCGTCGTGAAAT
CGGACGACAAGCGCGAAGCCTTCGATCGTTCGAAGCTCGAACAATCGGTCACGCTCGCGTGCCGCAAGCGCGGCGTTACG
CAGGAGCAGATCGACCAGCTCGTCTCGGGCATCCAGCGGCAGGTCGAGACAGCGGGCGAAGGCGAGATCGCTTCGACCCG
GATCGGCGAAATGGTGATGGACGGACTGCGCCAGATCGACAGCGTCGCCTATATCCGCTTTGCCAGTGTCTATCGCGACT
TCAGTGAGGCGCGGGACTTCGAGGAATTCGCCAGCACGGTGCAGGAAGCGGCGAAGGACTAG

Upstream 100 bases:

>100_bases
TGGTGCCGTCGCTGCGGCAGTGCTACCCCTCGTCTCATGGCCCATCGGCCTCGCTGCCGGCGCCGTCTATGCGCTGCATA
CGAGGATCAAGAAGTAGACG

Downstream 100 bases:

>100_bases
AGATGTTCTGGGCTTACATGATCCGTTGCGGCGACGGGACGTTCTACACGGGTCATACAGACGATCTTGAAATGAGATGG
GCTCAGCATCTCGATGGGTC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MRCPFCAHDDSQVKDSRPAEDNAAIRRRRQCSKCGARFTTFERVQLRDVTVVKSDDKREAFDRSKLEQSVTLACRKRGVT
QEQIDQLVSGIQRQVETAGEGEIASTRIGEMVMDGLRQIDSVAYIRFASVYRDFSEARDFEEFASTVQEAAKD

Sequences:

>Translated_153_residues
MRCPFCAHDDSQVKDSRPAEDNAAIRRRRQCSKCGARFTTFERVQLRDVTVVKSDDKREAFDRSKLEQSVTLACRKRGVT
QEQIDQLVSGIQRQVETAGEGEIASTRIGEMVMDGLRQIDSVAYIRFASVYRDFSEARDFEEFASTVQEAAKD
>Mature_153_residues
MRCPFCAHDDSQVKDSRPAEDNAAIRRRRQCSKCGARFTTFERVQLRDVTVVKSDDKREAFDRSKLEQSVTLACRKRGVT
QEQIDQLVSGIQRQVETAGEGEIASTRIGEMVMDGLRQIDSVAYIRFASVYRDFSEARDFEEFASTVQEAAKD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=142, Percent_Identity=45.0704225352113, Blast_Score=130, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_ERYLH (Q2NAS1)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458017.1
- STRING:   Q2NAS1
- GeneID:   3870679
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_05640
- NMPDR:   fig|314225.3.peg.1936
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q2NAS1
- ProtClustDB:   PRK00464
- BioCyc:   ELIT314225:ELI_05640-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17407; Mature: 17407

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCAHDDSQVKDSRPAEDNAAIRRRRQCSKCGARFTTFERVQLRDVTVVKSDDKREA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCHHHH
FDRSKLEQSVTLACRKRGVTQEQIDQLVSGIQRQVETAGEGEIASTRIGEMVMDGLRQID
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
SVAYIRFASVYRDFSEARDFEEFASTVQEAAKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRCPFCAHDDSQVKDSRPAEDNAAIRRRRQCSKCGARFTTFERVQLRDVTVVKSDDKREA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCHHHH
FDRSKLEQSVTLACRKRGVTQEQIDQLVSGIQRQVETAGEGEIASTRIGEMVMDGLRQID
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
SVAYIRFASVYRDFSEARDFEEFASTVQEAAKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA