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The map label for this gene is serB [H]

Identifier: 85373932

GI number: 85373932

Start: 1148055

End: 1148930

Strand: Direct

Name: serB [H]

Synonym: ELI_05525

Alternate gene names: 85373932

Gene position: 1148055-1148930 (Clockwise)

Preceding gene: 85373924

Following gene: 85373933

Centisome position: 37.61

GC content: 62.56

Gene sequence:

>876_bases
ATGCTCATCGTCCGCCTGATAGCAGACCCCGCCGGGTTGGAAACGCGGATCAAGAACCTCCGCGCGGCGTGGGATGACAA
GGGCTGGTCGTCGCGCATCGAGAGGGACGCAGGCGCCATGGTCGAGCTGCGCGTTTCGAGTTGGGACGTTGCAGAAGTGC
GCGTGACTATCGACGAGCGCATCGGGCCGAGCGATGGCCTCGTAACGGCAATCCCCCCTGTCACCCCGCGTCTCTTCATC
TCCGACATGGATTCCACCATGATCGGGCAGGAATGCATCGACGAACTGGCCGACTATGCGGGGATCAAGCCGCAAATTGC
CGCCATCACCGAACGCGCGATGCAGGGCGAGCTCGATTTCGAAGCCGCACTACGTGAGCGGGTCGGGTTGCTCTGTGGGC
TGGAAGAAGGTGCGATTGCGCAGTGCCTTCATGAGCGCATTACGCCCAACCGCGGCGCGCGTATCGTGGTCGAAACGCTC
AAGGCGAAGGGATGCAAAACAGTGCTCGTCACCGGCGGATTCCATCACTTCGCCGATCCGGTCGCGGCGCAGATCGGCTT
CGAGCGCGTGGTCGGCAACCGTCTTGAGGTTTCAGACGGAAAGTTGACCGGTGGCCTCGACGGACCGGTCGTCGACAGCT
CGGTAAAGCAATCGGTGCTCGAGGAAGAGATGCAAGCTCTCGGCGCTCGCGCGACCAGCCTCGCGGCGGGCGACGGGGCC
AATGACATTCCGATGCTGGACGCGGCCGATATCGGCGTTGCCTATCGCGCCAAGCCGAAAGCGCGCGCATCGGCAAACTG
CTGGATCGATCGGGGAGACCTGACATCGATCCTCATACTTCTGGGTATCGCCACAGAAGACTGGGCGGAAACCTAA

Upstream 100 bases:

>100_bases
CAGCGCCAGCCGCACCGCGACATCGCTCTTGCCGCTGGCGGTCGGCCCTGCAATGAGCGCCACCGGCGGTTTTTCGCCCC
AATCTTCCGGAGTTTGCCCC

Downstream 100 bases:

>100_bases
ACGCGAATGCCTGTTTCATCCTATATTGACACTCGTGTCAGTAGTAGCGAAGGGGAACTCCCACCCCATGAAGACGATGA
TGAAACAGACTCCTTCCCCC

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MLIVRLIADPAGLETRIKNLRAAWDDKGWSSRIERDAGAMVELRVSSWDVAEVRVTIDERIGPSDGLVTAIPPVTPRLFI
SDMDSTMIGQECIDELADYAGIKPQIAAITERAMQGELDFEAALRERVGLLCGLEEGAIAQCLHERITPNRGARIVVETL
KAKGCKTVLVTGGFHHFADPVAAQIGFERVVGNRLEVSDGKLTGGLDGPVVDSSVKQSVLEEEMQALGARATSLAAGDGA
NDIPMLDAADIGVAYRAKPKARASANCWIDRGDLTSILILLGIATEDWAET

Sequences:

>Translated_291_residues
MLIVRLIADPAGLETRIKNLRAAWDDKGWSSRIERDAGAMVELRVSSWDVAEVRVTIDERIGPSDGLVTAIPPVTPRLFI
SDMDSTMIGQECIDELADYAGIKPQIAAITERAMQGELDFEAALRERVGLLCGLEEGAIAQCLHERITPNRGARIVVETL
KAKGCKTVLVTGGFHHFADPVAAQIGFERVVGNRLEVSDGKLTGGLDGPVVDSSVKQSVLEEEMQALGARATSLAAGDGA
NDIPMLDAADIGVAYRAKPKARASANCWIDRGDLTSILILLGIATEDWAET
>Mature_291_residues
MLIVRLIADPAGLETRIKNLRAAWDDKGWSSRIERDAGAMVELRVSSWDVAEVRVTIDERIGPSDGLVTAIPPVTPRLFI
SDMDSTMIGQECIDELADYAGIKPQIAAITERAMQGELDFEAALRERVGLLCGLEEGAIAQCLHERITPNRGARIVVETL
KAKGCKTVLVTGGFHHFADPVAAQIGFERVVGNRLEVSDGKLTGGLDGPVVDSSVKQSVLEEEMQALGARATSLAAGDGA
NDIPMLDAADIGVAYRAKPKARASANCWIDRGDLTSILILLGIATEDWAET

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1790849, Length=208, Percent_Identity=42.3076923076923, Blast_Score=150, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI115534454, Length=194, Percent_Identity=29.8969072164948, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=213, Percent_Identity=39.4366197183099, Blast_Score=156, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24661601, Length=202, Percent_Identity=28.2178217821782, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31187; Mature: 31187

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIVRLIADPAGLETRIKNLRAAWDDKGWSSRIERDAGAMVELRVSSWDVAEVRVTIDER
CEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEEEECC
IGPSDGLVTAIPPVTPRLFISDMDSTMIGQECIDELADYAGIKPQIAAITERAMQGELDF
CCCCCCEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCH
EAALRERVGLLCGLEEGAIAQCLHERITPNRGARIVVETLKAKGCKTVLVTGGFHHFADP
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHCCCCCEEEEECCCHHHHHH
VAAQIGFERVVGNRLEVSDGKLTGGLDGPVVDSSVKQSVLEEEMQALGARATSLAAGDGA
HHHHHHHHHHHCCEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHEECCCCC
NDIPMLDAADIGVAYRAKPKARASANCWIDRGDLTSILILLGIATEDWAET
CCCCCCCCCCCCEEEECCCCCCCCCCCEEECCHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MLIVRLIADPAGLETRIKNLRAAWDDKGWSSRIERDAGAMVELRVSSWDVAEVRVTIDER
CEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEEEECC
IGPSDGLVTAIPPVTPRLFISDMDSTMIGQECIDELADYAGIKPQIAAITERAMQGELDF
CCCCCCEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCH
EAALRERVGLLCGLEEGAIAQCLHERITPNRGARIVVETLKAKGCKTVLVTGGFHHFADP
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHCCCCCEEEEECCCHHHHHH
VAAQIGFERVVGNRLEVSDGKLTGGLDGPVVDSSVKQSVLEEEMQALGARATSLAAGDGA
HHHHHHHHHHHCCEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHEECCCCC
NDIPMLDAADIGVAYRAKPKARASANCWIDRGDLTSILILLGIATEDWAET
CCCCCCCCCCCCEEEECCCCCCCCCCCEEECCHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]