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The map label for this gene is 85373904

Identifier: 85373904

GI number: 85373904

Start: 1116540

End: 1117970

Strand: Direct

Name: 85373904

Synonym: ELI_05385

Alternate gene names: NA

Gene position: 1116540-1117970 (Clockwise)

Preceding gene: 85373903

Following gene: 85373905

Centisome position: 36.58

GC content: 66.88

Gene sequence:

>1431_bases
GTGACCTCGCTCCAGCACGTCAAGCTCGGCACCTATTACGTGGTCAATCTGCCGCGTCCGGACGACTTTGCCTTCTGGCG
CGAGCGGGCGCGTAGCCTCGTGCAATGCGATGTCCCGCCCGACCGGGTGGCGTGGGTCGAGTCGGGCGGGTCGGGCGATC
TCTTCGCCGGCGGCGATACGCGGCTGCCGGTGCCGCCCGCCGATGCCCGCCCGATCCGCGCCAGCAAGCGGTTCCTGAGC
CTTGCGAAGAACGCCGCGCTGCATTCCGATCCGGAGCGGTTCACGCTGCTCTACCGGCTCGTGTGGCGGCTCCAGCGCAA
CCCGCGGATGATGGAGGACAGGGCCGATGCCGATGTCCGGCGGATCGAGGAGCTCGACAAGAATGTCCGCCGCGACAGCC
ACAAGATGCACGCCTTCGTCCGCTTCCGGCAAGTCAAGGAAGAGGATGGCAGCGAGCATTACGTCGCGTGGTTCGAGCCC
GACCATCACATCGTGCGCGCCAATGCCGGGTTCTTCAAACGCCGCTTCGCCAATATGCGCTGGTCGATCCTGACCCCGCG
CGGGACGCTGCACTGGGACGGCGCGACGATGCGCGAAGGTCCGCCTGCGCAGAAGAGCGACGCGCCGCAGGGCGATCCGG
CGGAGGATCTGTGGCGCACCTATTACGCATCCATTTTCAATCCCGCGCGTTTGAAGGTCGGGGCGATGCTCTCCGAGATG
CCCAAGAAATACTGGAAGAACCTGCCCGAGGCCTCGCTCATTCCCGAGTTGATCGCCGGGGCGCAATCACGCGAGGCGAC
GATGGTGGATGCAGGCAGCCGCGAGCTGGAAGACCGGCCCGAGACGCTGGAAGCGATCGACCGTGCGATCCATGCCTGCC
GCCAGTGCCCGATCGGCGAGCTCGACAACCAGGCGGTGATGGGCGAGGGGCCGCAGGCTGCGGCCCTGATGATCGTCGGC
GAGCAACCGGGCGACCAGGAGGACAAGGCCGGGCGGCCGTTCGTGGGGCCGGCGGGACAACTGCTCGACCGCCATCTCGA
AAAGGCCGGGATCGAGCGGCGCGGCGCCTACGTCACCAACACGGTCAAGCATTTCAAGTTTGCGCAACGCGGAAAGCGGC
GGCTGCACCAGTCGCCGACTGCGAAGGAAATCGACACCTGCCGCTGGTGGATCGAAAGCGAGCGCGCGCTGGTGAAGCCG
AAGATCGTGCTCGCATTGGGCGCCAGCGCCGCGCGCGGGATGCTCGGCAAGACGGTGAGCATTTCCAAGGTGCGCGGCGA
GCCGATCGCGCTGGAAGATGGCAGCGAGTTGTGGGTGACCGCGCACCCGTCCTACCTGCTGCGGCTCGATGGGGAGGCTG
CGGAGAAGCAGGCCAAGCTGTTCGATGCCGACCTCGCCGCGGTGAAAGAGCGGTTGGGGGAGTTGTCATGA

Upstream 100 bases:

>100_bases
ATCCGTCATCCCAGCGAAAGCTGGGATCTCTCGCCGCTAAGTCGGATTTGGCTGCACGAGACCCCAGCTTTCGCTGGGGC
GACGGCTTGGGGGACCCGTC

Downstream 100 bases:

>100_bases
GTATCGTCATCCCAGCGGAAGCTGGGATCTGGTGCGTCCGGGCCGGACATTGCTGCACGAGATCCCAGCTTCCGCTGGGA
TGACGGGGCGGGGAGGCCTG

Product: Uracil-DNA glycosylase:Phage SPO1 DNA polymerase-related protein

Products: diphosphate; DNAn+1

Alternate protein names: Uracil-DNA Glycosylase; DNA Polymerase Related Protein; Uracil-DNA Glycosylase Superfamily Protein; Phage SPO1 DNA Polymerase-Like Protein; Uracil DNA Glycosylase Superfamily Protein; Uracil-DNA Glycosylase Superfamily; DNA Polymerase; DNA Polymerase Bacteriophage-Type; DNA-Directed DNA Polymerase Protein; Phage Spo1 DNA Polymerase-Related Protein; DNA Polymerase-Related Protein; DNA Polymerase-Related Protein Bacteriophage-Type; Uracil-DNA Glycosylase Family 4 Protein; N-Terminus Of Bacteriophage-Type DNA Polymerase; DNA-Directed DNA Polymerase; Helicase/Glycosylase; Uracil DNA Glycosylase Protein; Uracil DNA Glycosylase; DNA-Directed DNA Polymerase Bacteriophage-Type; Uracil DNA Glycosylase Superfamily; Phage DNA Polymerase; Phage SPO1 DNA Polymerase; Uracil DNA Glycosylase Family Protein; Transcriptional Regulator Fis Family; Uracil-DNA Glycosylase-Related Protein; N-Terminus Of Phage SPO1 DNA Polymerase; Fis Family Transcriptional Regulator; DNA Polymerase-Like Protein; Leucyl-TRNA Synthetase

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MTSLQHVKLGTYYVVNLPRPDDFAFWRERARSLVQCDVPPDRVAWVESGGSGDLFAGGDTRLPVPPADARPIRASKRFLS
LAKNAALHSDPERFTLLYRLVWRLQRNPRMMEDRADADVRRIEELDKNVRRDSHKMHAFVRFRQVKEEDGSEHYVAWFEP
DHHIVRANAGFFKRRFANMRWSILTPRGTLHWDGATMREGPPAQKSDAPQGDPAEDLWRTYYASIFNPARLKVGAMLSEM
PKKYWKNLPEASLIPELIAGAQSREATMVDAGSRELEDRPETLEAIDRAIHACRQCPIGELDNQAVMGEGPQAAALMIVG
EQPGDQEDKAGRPFVGPAGQLLDRHLEKAGIERRGAYVTNTVKHFKFAQRGKRRLHQSPTAKEIDTCRWWIESERALVKP
KIVLALGASAARGMLGKTVSISKVRGEPIALEDGSELWVTAHPSYLLRLDGEAAEKQAKLFDADLAAVKERLGELS

Sequences:

>Translated_476_residues
MTSLQHVKLGTYYVVNLPRPDDFAFWRERARSLVQCDVPPDRVAWVESGGSGDLFAGGDTRLPVPPADARPIRASKRFLS
LAKNAALHSDPERFTLLYRLVWRLQRNPRMMEDRADADVRRIEELDKNVRRDSHKMHAFVRFRQVKEEDGSEHYVAWFEP
DHHIVRANAGFFKRRFANMRWSILTPRGTLHWDGATMREGPPAQKSDAPQGDPAEDLWRTYYASIFNPARLKVGAMLSEM
PKKYWKNLPEASLIPELIAGAQSREATMVDAGSRELEDRPETLEAIDRAIHACRQCPIGELDNQAVMGEGPQAAALMIVG
EQPGDQEDKAGRPFVGPAGQLLDRHLEKAGIERRGAYVTNTVKHFKFAQRGKRRLHQSPTAKEIDTCRWWIESERALVKP
KIVLALGASAARGMLGKTVSISKVRGEPIALEDGSELWVTAHPSYLLRLDGEAAEKQAKLFDADLAAVKERLGELS
>Mature_475_residues
TSLQHVKLGTYYVVNLPRPDDFAFWRERARSLVQCDVPPDRVAWVESGGSGDLFAGGDTRLPVPPADARPIRASKRFLSL
AKNAALHSDPERFTLLYRLVWRLQRNPRMMEDRADADVRRIEELDKNVRRDSHKMHAFVRFRQVKEEDGSEHYVAWFEPD
HHIVRANAGFFKRRFANMRWSILTPRGTLHWDGATMREGPPAQKSDAPQGDPAEDLWRTYYASIFNPARLKVGAMLSEMP
KKYWKNLPEASLIPELIAGAQSREATMVDAGSRELEDRPETLEAIDRAIHACRQCPIGELDNQAVMGEGPQAAALMIVGE
QPGDQEDKAGRPFVGPAGQLLDRHLEKAGIERRGAYVTNTVKHFKFAQRGKRRLHQSPTAKEIDTCRWWIESERALVKPK
IVLALGASAARGMLGKTVSISKVRGEPIALEDGSELWVTAHPSYLLRLDGEAAEKQAKLFDADLAAVKERLGELS

Specific function: Unknown

COG id: COG1573

COG function: function code L; Uracil-DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 53591; Mature: 53459

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLQHVKLGTYYVVNLPRPDDFAFWRERARSLVQCDVPPDRVAWVESGGSGDLFAGGDT
CCCCCEEEECEEEEEECCCCCCHHHHHHHHHHHEECCCCCCCEEEEECCCCCCEECCCCC
RLPVPPADARPIRASKRFLSLAKNAALHSDPERFTLLYRLVWRLQRNPRMMEDRADADVR
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHH
RIEELDKNVRRDSHKMHAFVRFRQVKEEDGSEHYVAWFEPDHHIVRANAGFFKRRFANMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCHHHHHHHCCCC
WSILTPRGTLHWDGATMREGPPAQKSDAPQGDPAEDLWRTYYASIFNPARLKVGAMLSEM
EEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
PKKYWKNLPEASLIPELIAGAQSREATMVDAGSRELEDRPETLEAIDRAIHACRQCPIGE
HHHHHHCCCCHHHHHHHHCCCCCCCCEEECCCCHHHCCCHHHHHHHHHHHHHHHCCCCCC
LDNQAVMGEGPQAAALMIVGEQPGDQEDKAGRPFVGPAGQLLDRHLEKAGIERRGAYVTN
CCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHCCCHHHH
TVKHFKFAQRGKRRLHQSPTAKEIDTCRWWIESERALVKPKIVLALGASAARGMLGKTVS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECCEEEEEECCHHHHHHHCCCEE
ISKVRGEPIALEDGSELWVTAHPSYLLRLDGEAAEKQAKLFDADLAAVKERLGELS
EEEECCCEEEEECCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSLQHVKLGTYYVVNLPRPDDFAFWRERARSLVQCDVPPDRVAWVESGGSGDLFAGGDT
CCCCEEEECEEEEEECCCCCCHHHHHHHHHHHEECCCCCCCEEEEECCCCCCEECCCCC
RLPVPPADARPIRASKRFLSLAKNAALHSDPERFTLLYRLVWRLQRNPRMMEDRADADVR
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHH
RIEELDKNVRRDSHKMHAFVRFRQVKEEDGSEHYVAWFEPDHHIVRANAGFFKRRFANMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCHHHHHHHCCCC
WSILTPRGTLHWDGATMREGPPAQKSDAPQGDPAEDLWRTYYASIFNPARLKVGAMLSEM
EEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
PKKYWKNLPEASLIPELIAGAQSREATMVDAGSRELEDRPETLEAIDRAIHACRQCPIGE
HHHHHHCCCCHHHHHHHHCCCCCCCCEEECCCCHHHCCCHHHHHHHHHHHHHHHCCCCCC
LDNQAVMGEGPQAAALMIVGEQPGDQEDKAGRPFVGPAGQLLDRHLEKAGIERRGAYVTN
CCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHCCCHHHH
TVKHFKFAQRGKRRLHQSPTAKEIDTCRWWIESERALVKPKIVLALGASAARGMLGKTVS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECCEEEEEECCHHHHHHHCCCEE
ISKVRGEPIALEDGSELWVTAHPSYLLRLDGEAAEKQAKLFDADLAAVKERLGELS
EEEECCCEEEEECCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA