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The map label for this gene is cbbT [H]

Identifier: 85373868

GI number: 85373868

Start: 1077088

End: 1079067

Strand: Direct

Name: cbbT [H]

Synonym: ELI_05205

Alternate gene names: 85373868

Gene position: 1077088-1079067 (Clockwise)

Preceding gene: 85373862

Following gene: 85373869

Centisome position: 35.29

GC content: 63.69

Gene sequence:

>1980_bases
ATGAGCCTCGATCCCGCCCGCCTCGCGCCCATGGCCAACGCCATTCGCGCGCTTTCGATGGATGCGGTTCAGGCGGCGAA
TTCGGGACACCCTGGCATGCCGATGGGCATGGCCGATGTGGCGACGGTGTTGTGGTCGCAGTTCCTCAAGTTCGATCCCG
CGGCGCCCGACTGGGCCGACCGCGATCGCTTCGTGCTGAGCGCGGGCCATGGTTCGATGCTGATCTACAGCCTGCTCCAT
CTGTCGGGCTATGCGCAGCCGACGATGGAGGACATCCGCAATTTTCGCCAACTCGGCAGCCCGTGTGCAGGCCACCCGGA
GAACTTCCTCCTGCCGGGGGTCGAATGCACCACCGGGCCGCTGGGGCAAGGGCTCGCCATGGCCGTCGGCATGGCGATGG
CGGAGCGGCACCTCAATGCGTTGTTCGGCGATGACCTGGTCGATCACCGCACGTGGGTGATTGCGGGCGACGGGTGCCTG
ATGGAAGGCATCAACCATGAGGCGATCGGTTTGGCCGGTCATCTCAAGCTGGGCCGCCTCAACGTTTTGTGGGACGACAA
CAACATTACCATCGATGGCGAGACGGACCTGTCCACCAGCGAGGACATCAAGGCGCGCTATGCCGCAACCGGTTGGCATG
TCGCAGAATGCGACGGTCACGATTTTGCCGACATCGCCCGCGCGCTGGAAGAAGCCGCCGCCGACGATCGCCCCTCATTG
GTTGCCTGCAAGACGGTGATCGGCAAGGGCGCGCCGAACAAGCAGGGCACCAGCGCCACGCACGGTGCGGCCTTGGGCGA
GGACGAAGTAGCCGCAGCGCGCGAAACGCTGGGGTGGGACGCCGAACCTTTCGTCATTCCCGAGGACATCCTGGCCGACT
GGCGCTCGACCGGCGAGCGCGGCCGGGACGCGCATGGAGCGTGGGAAAGCCGGGTAGACGGCAGCGAGCACAAAGACGAA
TTCCAGCGACGGATGGCGGGCGAGCTACCGCATGGTGACGCGTCGAAGGACTATATCGCCTCACTCGTCGAGAATCCGGC
CAAGGTCGCAACCCGCAAGGCGAGCGAGATGGCGCTGGCCGAGATCAATTCGCGCCTGCCGGACACCATCGGCGGCAGCG
CCGATTTGACGGGTTCGAACAATACGAAAGCCGGCGGCATCGAGGCGATGACGGCGGACGATTATTCGGGCCGGTACGTT
TATTACGGCATCCGTGAATTCGGCATGGCGGCGGCGATGAACGGTATGGCGTTGCATGGCGGGGTGATTCCTTACGGCGG
CACGTTCCTGGTGTTCACCGACTATGCGCGCGGCGCGATCCGCCTCTCGGCGTTGCAGGAAGCGCGCGTCATCTACGTGA
TGACGCATGACAGCATTGGCTTGGGCGAGGACGGCCCGACGCATCAGCCTGTCGAGCATCTTGCTTCGCTCAGAGCGATG
CCCAACCTCCTCGTCATGCGCCCGGCAGACGCGGTCGAGACTGCCGAATGCTGGGAAATTGCGCTGCGCAACGCGACCCG
ACCCAGCATCCTTGCCCTCAGCCGTCAGGGTCTGCCGCAGATGAGGCTCGAGGCAGTGGATGGCAATCTGAGCGAGAAGG
GCGGCTACCGGATCAAAGCTGCGGAGACAGAACGCAGGGTCGTGATTGTCGCTAGTGGCTCGGAGTTGCATGTCGCCGCC
GAATGTGCAGCCAAGCTGGAAGAGCAGGGCATCGGCGCAGAGGTGGTGTCCATGGTCAGCACCGAACTGTTCGAGGAGCA
GGACGAAAGCTATCAGGCCGACCTCCTCCCCGCCGACGTGTTCAAGGTATCGATCGAGGCGGGCTCCACCTTCGGCTGGG
ATCGCTACGTGGGTTCCGACGGGCTGAAGATCGGTCTCGATCGTTTCGGAGCTTCCGCTCCGGCAGGCGACCTGTTCGAA
AAATTCGGTTTCACTGCGGACGCCATCGTCCCGCAAATACTCAACAAGATCAAAGCATAA

Upstream 100 bases:

>100_bases
GACCAAGCCGAGGCTGTTCTTGACCTCTTGGCGAGGCTCCGCGAAGGCTGCGCGCGCGGCGAATCGCCGCTCAAATTTCA
CGCGCAGGAGCCTTCCGCCC

Downstream 100 bases:

>100_bases
GCAGGAGTTCTTCATGGCTACCAAAGTTGCCATCAACGGTTTCGGACGTATCGGCCGCCTCGTGGCGCGCGCCATTCTCG
AGCGCGACGATCACGATCTC

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MSLDPARLAPMANAIRALSMDAVQAANSGHPGMPMGMADVATVLWSQFLKFDPAAPDWADRDRFVLSAGHGSMLIYSLLH
LSGYAQPTMEDIRNFRQLGSPCAGHPENFLLPGVECTTGPLGQGLAMAVGMAMAERHLNALFGDDLVDHRTWVIAGDGCL
MEGINHEAIGLAGHLKLGRLNVLWDDNNITIDGETDLSTSEDIKARYAATGWHVAECDGHDFADIARALEEAAADDRPSL
VACKTVIGKGAPNKQGTSATHGAALGEDEVAAARETLGWDAEPFVIPEDILADWRSTGERGRDAHGAWESRVDGSEHKDE
FQRRMAGELPHGDASKDYIASLVENPAKVATRKASEMALAEINSRLPDTIGGSADLTGSNNTKAGGIEAMTADDYSGRYV
YYGIREFGMAAAMNGMALHGGVIPYGGTFLVFTDYARGAIRLSALQEARVIYVMTHDSIGLGEDGPTHQPVEHLASLRAM
PNLLVMRPADAVETAECWEIALRNATRPSILALSRQGLPQMRLEAVDGNLSEKGGYRIKAAETERRVVIVASGSELHVAA
ECAAKLEEQGIGAEVVSMVSTELFEEQDESYQADLLPADVFKVSIEAGSTFGWDRYVGSDGLKIGLDRFGASAPAGDLFE
KFGFTADAIVPQILNKIKA

Sequences:

>Translated_659_residues
MSLDPARLAPMANAIRALSMDAVQAANSGHPGMPMGMADVATVLWSQFLKFDPAAPDWADRDRFVLSAGHGSMLIYSLLH
LSGYAQPTMEDIRNFRQLGSPCAGHPENFLLPGVECTTGPLGQGLAMAVGMAMAERHLNALFGDDLVDHRTWVIAGDGCL
MEGINHEAIGLAGHLKLGRLNVLWDDNNITIDGETDLSTSEDIKARYAATGWHVAECDGHDFADIARALEEAAADDRPSL
VACKTVIGKGAPNKQGTSATHGAALGEDEVAAARETLGWDAEPFVIPEDILADWRSTGERGRDAHGAWESRVDGSEHKDE
FQRRMAGELPHGDASKDYIASLVENPAKVATRKASEMALAEINSRLPDTIGGSADLTGSNNTKAGGIEAMTADDYSGRYV
YYGIREFGMAAAMNGMALHGGVIPYGGTFLVFTDYARGAIRLSALQEARVIYVMTHDSIGLGEDGPTHQPVEHLASLRAM
PNLLVMRPADAVETAECWEIALRNATRPSILALSRQGLPQMRLEAVDGNLSEKGGYRIKAAETERRVVIVASGSELHVAA
ECAAKLEEQGIGAEVVSMVSTELFEEQDESYQADLLPADVFKVSIEAGSTFGWDRYVGSDGLKIGLDRFGASAPAGDLFE
KFGFTADAIVPQILNKIKA
>Mature_658_residues
SLDPARLAPMANAIRALSMDAVQAANSGHPGMPMGMADVATVLWSQFLKFDPAAPDWADRDRFVLSAGHGSMLIYSLLHL
SGYAQPTMEDIRNFRQLGSPCAGHPENFLLPGVECTTGPLGQGLAMAVGMAMAERHLNALFGDDLVDHRTWVIAGDGCLM
EGINHEAIGLAGHLKLGRLNVLWDDNNITIDGETDLSTSEDIKARYAATGWHVAECDGHDFADIARALEEAAADDRPSLV
ACKTVIGKGAPNKQGTSATHGAALGEDEVAAARETLGWDAEPFVIPEDILADWRSTGERGRDAHGAWESRVDGSEHKDEF
QRRMAGELPHGDASKDYIASLVENPAKVATRKASEMALAEINSRLPDTIGGSADLTGSNNTKAGGIEAMTADDYSGRYVY
YGIREFGMAAAMNGMALHGGVIPYGGTFLVFTDYARGAIRLSALQEARVIYVMTHDSIGLGEDGPTHQPVEHLASLRAMP
NLLVMRPADAVETAECWEIALRNATRPSILALSRQGLPQMRLEAVDGNLSEKGGYRIKAAETERRVVIVASGSELHVAAE
CAAKLEEQGIGAEVVSMVSTELFEEQDESYQADLLPADVFKVSIEAGSTFGWDRYVGSDGLKIGLDRFGASAPAGDLFEK
FGFTADAIVPQILNKIKA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=581, Percent_Identity=25.6454388984509, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI4507521, Length=581, Percent_Identity=25.6454388984509, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI133778974, Length=578, Percent_Identity=26.643598615917, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI225637459, Length=594, Percent_Identity=22.5589225589226, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI225637463, Length=491, Percent_Identity=23.4215885947047, Blast_Score=110, Evalue=6e-24,
Organism=Homo sapiens, GI225637461, Length=563, Percent_Identity=22.0248667850799, Blast_Score=109, Evalue=8e-24,
Organism=Escherichia coli, GI48994911, Length=656, Percent_Identity=52.4390243902439, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=653, Percent_Identity=50.8422664624809, Blast_Score=624, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17539652, Length=573, Percent_Identity=27.3996509598604, Blast_Score=176, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6325331, Length=658, Percent_Identity=45.1367781155015, Blast_Score=526, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6319593, Length=658, Percent_Identity=43.161094224924, Blast_Score=495, Evalue=1e-141,
Organism=Drosophila melanogaster, GI45551847, Length=584, Percent_Identity=26.7123287671233, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI45550715, Length=584, Percent_Identity=26.7123287671233, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24666278, Length=571, Percent_Identity=27.1453590192644, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24645119, Length=550, Percent_Identity=26.1818181818182, Blast_Score=152, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 70491; Mature: 70360

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDPARLAPMANAIRALSMDAVQAANSGHPGMPMGMADVATVLWSQFLKFDPAAPDWAD
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
RDRFVLSAGHGSMLIYSLLHLSGYAQPTMEDIRNFRQLGSPCAGHPENFLLPGVECTTGP
CCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
LGQGLAMAVGMAMAERHLNALFGDDLVDHRTWVIAGDGCLMEGINHEAIGLAGHLKLGRL
CCCHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEEECCCHHCCCCCCCCEEEEECEEECEE
NVLWDDNNITIDGETDLSTSEDIKARYAATGWHVAECDGHDFADIARALEEAAADDRPSL
EEEECCCEEEECCCCCCCCCHHHHHHHEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCC
VACKTVIGKGAPNKQGTSATHGAALGEDEVAAARETLGWDAEPFVIPEDILADWRSTGER
EEHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
GRDAHGAWESRVDGSEHKDEFQRRMAGELPHGDASKDYIASLVENPAKVATRKASEMALA
CCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
EINSRLPDTIGGSADLTGSNNTKAGGIEAMTADDYSGRYVYYGIREFGMAAAMNGMALHG
HHHHCCCCCCCCCEECCCCCCCCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHCCEEEEC
GVIPYGGTFLVFTDYARGAIRLSALQEARVIYVMTHDSIGLGEDGPTHQPVEHLASLRAM
CCCCCCCEEEEEECCCCCCEEHEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHC
PNLLVMRPADAVETAECWEIALRNATRPSILALSRQGLPQMRLEAVDGNLSEKGGYRIKA
CCEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEHHCCCCHHHHHHHCCCCCCCCCEEEEE
AETERRVVIVASGSELHVAAECAAKLEEQGIGAEVVSMVSTELFEEQDESYQADLLPADV
ECCCCEEEEEECCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEE
FKVSIEAGSTFGWDRYVGSDGLKIGLDRFGASAPAGDLFEKFGFTADAIVPQILNKIKA
EEEEEECCCCCCCHHHCCCCCCEECHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLDPARLAPMANAIRALSMDAVQAANSGHPGMPMGMADVATVLWSQFLKFDPAAPDWAD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
RDRFVLSAGHGSMLIYSLLHLSGYAQPTMEDIRNFRQLGSPCAGHPENFLLPGVECTTGP
CCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
LGQGLAMAVGMAMAERHLNALFGDDLVDHRTWVIAGDGCLMEGINHEAIGLAGHLKLGRL
CCCHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEEECCCHHCCCCCCCCEEEEECEEECEE
NVLWDDNNITIDGETDLSTSEDIKARYAATGWHVAECDGHDFADIARALEEAAADDRPSL
EEEECCCEEEECCCCCCCCCHHHHHHHEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCC
VACKTVIGKGAPNKQGTSATHGAALGEDEVAAARETLGWDAEPFVIPEDILADWRSTGER
EEHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
GRDAHGAWESRVDGSEHKDEFQRRMAGELPHGDASKDYIASLVENPAKVATRKASEMALA
CCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
EINSRLPDTIGGSADLTGSNNTKAGGIEAMTADDYSGRYVYYGIREFGMAAAMNGMALHG
HHHHCCCCCCCCCEECCCCCCCCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHCCEEEEC
GVIPYGGTFLVFTDYARGAIRLSALQEARVIYVMTHDSIGLGEDGPTHQPVEHLASLRAM
CCCCCCCEEEEEECCCCCCEEHEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHC
PNLLVMRPADAVETAECWEIALRNATRPSILALSRQGLPQMRLEAVDGNLSEKGGYRIKA
CCEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEHHCCCCHHHHHHHCCCCCCCCCEEEEE
AETERRVVIVASGSELHVAAECAAKLEEQGIGAEVVSMVSTELFEEQDESYQADLLPADV
ECCCCEEEEEECCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEE
FKVSIEAGSTFGWDRYVGSDGLKIGLDRFGASAPAGDLFEKFGFTADAIVPQILNKIKA
EEEEEECCCCCCCHHHCCCCCCEECHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA