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The map label for this gene is nudG [H]

Identifier: 85373829

GI number: 85373829

Start: 1029666

End: 1030058

Strand: Direct

Name: nudG [H]

Synonym: ELI_05010

Alternate gene names: 85373829

Gene position: 1029666-1030058 (Clockwise)

Preceding gene: 85373826

Following gene: 85373830

Centisome position: 33.73

GC content: 64.38

Gene sequence:

>393_bases
GTGCTGGTTGTCGCTGCGGCGCTTTCCGATGGGGAAGGGCGGTGGCTGATGCACCGCAGGCCCGTCGGTAAGGAGCATGC
GGGCCTGTGGGAGTTTCCCGGCGGCAAGGTCGAGCCAGGCGAAACCGTGCGGCAGGCGCTGGCGCGCGAGATGTTCGAGG
AGTCGGCGCTCAAGCTCGATATAGATGCGATGCGGGAAGCCGGTTTTGCGGCATCGGATGCCGCCGTCGATGGCCGCGGA
ATCGTTTTGCTGCTTTACACTTGTTCGCGGTGGAGCGGGTCGATCACGGCGAAAGAGGGCGGAGAGTTCAAATGGCACAG
ACCCGCCGAGATCGCCAGGCTGCCGAAGCCGCCGCTCGACGTCGAACTGGCGCGGCAACTGTTCGAAAAATAG

Upstream 100 bases:

>100_bases
ATAGACTCCACTCGCGTCTAGCCAGACAGCGCCCTTTTGATCCATCAGGGTAAAGAAAAGGTTCGCTGAAGATCGAAAAG
TGAAAAGAAACTTTACACAT

Downstream 100 bases:

>100_bases
CGGCGAAGGGGATTGCCAAGCCGTTGGCGCCCCCCTATGTGCCGCCCTCCGATGCGCGCCAGTAGCTCAGCTGGATAGAG
TACCTGACTACGAATCAGGC

Product: mutator MutT protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MLVVAAALSDGEGRWLMHRRPVGKEHAGLWEFPGGKVEPGETVRQALAREMFEESALKLDIDAMREAGFAASDAAVDGRG
IVLLLYTCSRWSGSITAKEGGEFKWHRPAEIARLPKPPLDVELARQLFEK

Sequences:

>Translated_130_residues
MLVVAAALSDGEGRWLMHRRPVGKEHAGLWEFPGGKVEPGETVRQALAREMFEESALKLDIDAMREAGFAASDAAVDGRG
IVLLLYTCSRWSGSITAKEGGEFKWHRPAEIARLPKPPLDVELARQLFEK
>Mature_130_residues
MLVVAAALSDGEGRWLMHRRPVGKEHAGLWEFPGGKVEPGETVRQALAREMFEESALKLDIDAMREAGFAASDAAVDGRG
IVLLLYTCSRWSGSITAKEGGEFKWHRPAEIARLPKPPLDVELARQLFEK

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=123, Percent_Identity=39.0243902439024, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14357; Mature: 14357

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVVAAALSDGEGRWLMHRRPVGKEHAGLWEFPGGKVEPGETVRQALAREMFEESALKLD
CEEEEEEECCCCCCEEEEECCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHCEEEC
IDAMREAGFAASDAAVDGRGIVLLLYTCSRWSGSITAKEGGEFKWHRPAEIARLPKPPLD
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCCCCCCCCCHHHHHCCCCCCC
VELARQLFEK
HHHHHHHHCC
>Mature Secondary Structure
MLVVAAALSDGEGRWLMHRRPVGKEHAGLWEFPGGKVEPGETVRQALAREMFEESALKLD
CEEEEEEECCCCCCEEEEECCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHCEEEC
IDAMREAGFAASDAAVDGRGIVLLLYTCSRWSGSITAKEGGEFKWHRPAEIARLPKPPLD
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCCCCCCCCCHHHHHCCCCCCC
VELARQLFEK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]