Click here to switch to the map view.

The map label for this gene is accA

Identifier: 85373825

GI number: 85373825

Start: 1026491

End: 1027435

Strand: Direct

Name: accA

Synonym: ELI_04990

Alternate gene names: 85373825

Gene position: 1026491-1027435 (Clockwise)

Preceding gene: 85373824

Following gene: 85373826

Centisome position: 33.63

GC content: 62.96

Gene sequence:

>945_bases
ATGAATTCCTATCTCGAATTCGAGAAGCCCGTTGCCCAGCTCGAAGCGCGGATCGCAGAATTGCGGTCGGCTGCCGAAGG
CGACGAGGTCGATATCTCGAACGAACTCAAGCGGCTCGAGCGCAAGAGCGCCGCGCTGCTTACCAGTACCTACTCTGCGC
TCACGCCGTGGCAGAAAACGCAGGTCGCGCGCCATCCGCAGCGTCCGCATTTTCGCGATTTCGTAAAGCATGCCTTCGAC
GAGTTCGTCCCGCTTGGCGGCGATCGCAATTACGGCGAAGATGAAGCGATCATGGGCGGCCTCGCGACCTTGCGCGGCCG
CAAGGTGGTGCTCATCGGTCATGAAAAGGGCAATGATACCGAGAGTCGGCTGCGCCACAATTTCGGCATGGGCAAACCGG
AAGGGTATCGCAAGGCGATCCGGCTGATGGACCTCGCCGGGCGTTTCGGACTGCCGGTCGTCACATTGGTCGACACATCG
GGCGCGTTTCCGGGCGTCGAGGCCGAAGAGCGCGGGCAGGCAGAGGCTATTGCCCGTTCGACCGAAGCCTGTCTGGCCTT
GCCGGTGCCGATGGTGGCTACGATTGTGGGCGAGGGCGGTTCGGGCGGCGCCGTGGCGCTCGCGAGCGCCGAGCGCGTGC
TGATGCTGGAGCACGCGGTCTATTCTGTCATCTCGCCCGAAGGCTGCGCGTCCATCTTGTGGCGCACGGCGGAAAAGGCG
CCCGATGCGGCAGAGGCCATGAAGGTGACCGCGCAGCATTTGCTCGATCTGAAGGTGATCGACCGGATCGTGAAGGAGCC
GACCGGTGGCGCGCATCGCGATCCTTCGGCGATCTGCGAAACGCTTGCCAATGCAATAGATGAGGAACTGGATGCCTTGG
CGGACTTGCCGGGCGAGACGCTGCGCCGCATGCGCGAAGAACGGTTTTTGCAGATCGGCGGATAA

Upstream 100 bases:

>100_bases
GCTCGTCGCGCTGGTCAACGAGCGCCATCCGCTGTCGGCGCGGGCAGCTGGCAAACGCAGCACGCTTGCAGAAAAGCGAA
CGGAGGACTAGCGCACCGGC

Downstream 100 bases:

>100_bases
CGCCGCGTCGCGGAACTTGCAGGGCCATTCGCACGTTTGATCTCTCGGTGGGAGCGGTTCGCTCGAGCGAAGCGCTTGAT
TCCGTACGAACCGAGGGACA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MNSYLEFEKPVAQLEARIAELRSAAEGDEVDISNELKRLERKSAALLTSTYSALTPWQKTQVARHPQRPHFRDFVKHAFD
EFVPLGGDRNYGEDEAIMGGLATLRGRKVVLIGHEKGNDTESRLRHNFGMGKPEGYRKAIRLMDLAGRFGLPVVTLVDTS
GAFPGVEAEERGQAEAIARSTEACLALPVPMVATIVGEGGSGGAVALASAERVLMLEHAVYSVISPEGCASILWRTAEKA
PDAAEAMKVTAQHLLDLKVIDRIVKEPTGGAHRDPSAICETLANAIDEELDALADLPGETLRRMREERFLQIGG

Sequences:

>Translated_314_residues
MNSYLEFEKPVAQLEARIAELRSAAEGDEVDISNELKRLERKSAALLTSTYSALTPWQKTQVARHPQRPHFRDFVKHAFD
EFVPLGGDRNYGEDEAIMGGLATLRGRKVVLIGHEKGNDTESRLRHNFGMGKPEGYRKAIRLMDLAGRFGLPVVTLVDTS
GAFPGVEAEERGQAEAIARSTEACLALPVPMVATIVGEGGSGGAVALASAERVLMLEHAVYSVISPEGCASILWRTAEKA
PDAAEAMKVTAQHLLDLKVIDRIVKEPTGGAHRDPSAICETLANAIDEELDALADLPGETLRRMREERFLQIGG
>Mature_314_residues
MNSYLEFEKPVAQLEARIAELRSAAEGDEVDISNELKRLERKSAALLTSTYSALTPWQKTQVARHPQRPHFRDFVKHAFD
EFVPLGGDRNYGEDEAIMGGLATLRGRKVVLIGHEKGNDTESRLRHNFGMGKPEGYRKAIRLMDLAGRFGLPVVTLVDTS
GAFPGVEAEERGQAEAIARSTEACLALPVPMVATIVGEGGSGGAVALASAERVLMLEHAVYSVISPEGCASILWRTAEKA
PDAAEAMKVTAQHLLDLKVIDRIVKEPTGGAHRDPSAICETLANAIDEELDALADLPGETLRRMREERFLQIGG

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=314, Percent_Identity=51.2738853503185, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_ERYLH (Q2NB51)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457887.1
- ProteinModelPortal:   Q2NB51
- SMR:   Q2NB51
- STRING:   Q2NB51
- GeneID:   3870161
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_04990
- NMPDR:   fig|314225.3.peg.2072
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   Q2NB51
- ProtClustDB:   PRK05724
- BioCyc:   ELIT314225:ELI_04990-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 34120; Mature: 34120

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSYLEFEKPVAQLEARIAELRSAAEGDEVDISNELKRLERKSAALLTSTYSALTPWQKT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVARHPQRPHFRDFVKHAFDEFVPLGGDRNYGEDEAIMGGLATLRGRKVVLIGHEKGNDT
HHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCH
ESRLRHNFGMGKPEGYRKAIRLMDLAGRFGLPVVTLVDTSGAFPGVEAEERGQAEAIARS
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHCCHHHHHHHH
TEACLALPVPMVATIVGEGGSGGAVALASAERVLMLEHAVYSVISPEGCASILWRTAEKA
HHHHHHCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
PDAAEAMKVTAQHLLDLKVIDRIVKEPTGGAHRDPSAICETLANAIDEELDALADLPGET
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
LRRMREERFLQIGG
HHHHHHHHHHHCCC
>Mature Secondary Structure
MNSYLEFEKPVAQLEARIAELRSAAEGDEVDISNELKRLERKSAALLTSTYSALTPWQKT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVARHPQRPHFRDFVKHAFDEFVPLGGDRNYGEDEAIMGGLATLRGRKVVLIGHEKGNDT
HHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCH
ESRLRHNFGMGKPEGYRKAIRLMDLAGRFGLPVVTLVDTSGAFPGVEAEERGQAEAIARS
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHCCHHHHHHHH
TEACLALPVPMVATIVGEGGSGGAVALASAERVLMLEHAVYSVISPEGCASILWRTAEKA
HHHHHHCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
PDAAEAMKVTAQHLLDLKVIDRIVKEPTGGAHRDPSAICETLANAIDEELDALADLPGET
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
LRRMREERFLQIGG
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA