Click here to switch to the map view.

The map label for this gene is maiA [H]

Identifier: 85373808

GI number: 85373808

Start: 1011783

End: 1012394

Strand: Direct

Name: maiA [H]

Synonym: ELI_04905

Alternate gene names: 85373808

Gene position: 1011783-1012394 (Clockwise)

Preceding gene: 85373807

Following gene: 85373809

Centisome position: 33.15

GC content: 62.09

Gene sequence:

>612_bases
ATGCTGTTCTACGACAGCCCGAACCCGGCGCCCAACCCACGCCGGGTGCGCATTTTCGCTGCCGAGAAAGGCATCGAGCT
GCCGAGCAAGCAAGTCTCGATCATCGAGCGCGAGCAGAAATCGGACGCGTACCTCAAGATCAATCCGCGCGGGCAAACCC
CGGCGCTGGAAACCGACGATGGCGAGGTCATCACCGAGAGCGTCGCGATCTGTCGCTATCTCGAAGCGCTGCATCCCGAT
CCTCCGCTGTTCGGCACCACGCCGCTCGAAATCGCGCATATCGAGCAATGGTGTCGCCGAGTCGAAATGATCCTGATGCC
GCCCATCGGCGCGGTGTGGGTTCACACGCATCCCTTCACCGCGCGCCTTCCGGGCCGCAATGCCGAATGGGGTGAAGCCA
ACCGCCTGCGGGTCGAGGACGCCTTCCGTTTCTTCGACACATCGCTGGAAGGGCGTGAATTTCTCGCCACGGATCGCTAT
ACGATGGCCGACATATTACTGGTTACGACGATGGATTTCGCCAAATTCGTGGGTTGCGGAGCGCCCGATGACTGTGCAGC
GCTCCACGCCTGGCACGACCATGTAAGCGCGCGGCCAAGCGCCGCTGCTTGA

Upstream 100 bases:

>100_bases
CCGAGGCGGAGGGCCAGCGCCTGGCCGGTGCCAGCGAAGACGCGGCGGAAGGCGGCAAAGCCTTTCTCGAGAAGCGCAAG
GCCCAGTTTAAGGGTCGCTG

Downstream 100 bases:

>100_bases
GGCATGAAATCACCTCCGTTGGTATCGAGCGGAGAACGCAGTTCCCTTCGGCTGGCTCCTAAGCAGCCGCTCAGGATAAA
CTACGTCGAGATGCAATTGC

Product: glutathione S-transferase family protein

Products: NA

Alternate protein names: MAAI [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MLFYDSPNPAPNPRRVRIFAAEKGIELPSKQVSIIEREQKSDAYLKINPRGQTPALETDDGEVITESVAICRYLEALHPD
PPLFGTTPLEIAHIEQWCRRVEMILMPPIGAVWVHTHPFTARLPGRNAEWGEANRLRVEDAFRFFDTSLEGREFLATDRY
TMADILLVTTMDFAKFVGCGAPDDCAALHAWHDHVSARPSAAA

Sequences:

>Translated_203_residues
MLFYDSPNPAPNPRRVRIFAAEKGIELPSKQVSIIEREQKSDAYLKINPRGQTPALETDDGEVITESVAICRYLEALHPD
PPLFGTTPLEIAHIEQWCRRVEMILMPPIGAVWVHTHPFTARLPGRNAEWGEANRLRVEDAFRFFDTSLEGREFLATDRY
TMADILLVTTMDFAKFVGCGAPDDCAALHAWHDHVSARPSAAA
>Mature_203_residues
MLFYDSPNPAPNPRRVRIFAAEKGIELPSKQVSIIEREQKSDAYLKINPRGQTPALETDDGEVITESVAICRYLEALHPD
PPLFGTTPLEIAHIEQWCRRVEMILMPPIGAVWVHTHPFTARLPGRNAEWGEANRLRVEDAFRFFDTSLEGREFLATDRY
TMADILLVTTMDFAKFVGCGAPDDCAALHAWHDHVSARPSAAA

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322968, Length=208, Percent_Identity=37.0192307692308, Blast_Score=127, Evalue=9e-31,
Organism=Drosophila melanogaster, GI17933730, Length=165, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28571670, Length=177, Percent_Identity=32.2033898305085, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17864592, Length=204, Percent_Identity=30.8823529411765, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR005955
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =5.2.1.2 [H]

Molecular weight: Translated: 22797; Mature: 22797

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFYDSPNPAPNPRRVRIFAAEKGIELPSKQVSIIEREQKSDAYLKINPRGQTPALETDD
CEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCEECCC
GEVITESVAICRYLEALHPDPPLFGTTPLEIAHIEQWCRRVEMILMPPIGAVWVHTHPFT
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCEEEEECCCCE
ARLPGRNAEWGEANRLRVEDAFRFFDTSLEGREFLATDRYTMADILLVTTMDFAKFVGCG
EECCCCCCCCCCCCEEEHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCC
APDDCAALHAWHDHVSARPSAAA
CCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLFYDSPNPAPNPRRVRIFAAEKGIELPSKQVSIIEREQKSDAYLKINPRGQTPALETDD
CEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCEECCC
GEVITESVAICRYLEALHPDPPLFGTTPLEIAHIEQWCRRVEMILMPPIGAVWVHTHPFT
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCEEEEECCCCE
ARLPGRNAEWGEANRLRVEDAFRFFDTSLEGREFLATDRYTMADILLVTTMDFAKFVGCG
EECCCCCCCCCCCCEEEHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCC
APDDCAALHAWHDHVSARPSAAA
CCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]