Click here to switch to the map view.

The map label for this gene is paaG [H]

Identifier: 85373807

GI number: 85373807

Start: 1010986

End: 1011783

Strand: Direct

Name: paaG [H]

Synonym: ELI_04900

Alternate gene names: 85373807

Gene position: 1010986-1011783 (Clockwise)

Preceding gene: 85373806

Following gene: 85373808

Centisome position: 33.12

GC content: 66.54

Gene sequence:

>798_bases
GTGGATTACGAAACCATCATCGTCGAGCGGGACGGCCCGCTGATGACCATCACCCTCAACCAGCCCGAGCGCCTCAACGC
CATGGCCCCGCAAATGGCCGATGAGATCGGCGCGGCGTTCTATGATCTGGGCGCAGGAGAAAATGGGGCGCGCGCGGTGC
TGATCACCGGGGCGGGCAAGGGATTCTGCTCGGGCGCGGACCTCTCGGCGCGCGGCGAGCGGAGCGCTCTGGCGATGAAT
GGCGGCAGTCACCTCGCGCTACAGAACCACTACAATCCCGCAATCAGCCAGGTGCTGCGCGCACCGGTGCCGGTGGTATG
CGCGGTCAACGGCCCGGCGGCGGGTGTCGGCTGCTCGCTGGGTCTGGCGGGCGATTTCACCATTGCCGGCAAGAGCGCCT
ATTTCCTGCAGGCCTTTGTCAATATCGGCCTCGTGCCGGACGGCGGCTCCACATGGCTGCTGACCCGCGCCATCGGTCGC
GCCCGCGCCACCCGCATGATGATGCTGGGCGAGAAGATCGGCGGCGAACAGGCCGAGGAATGGGGGTTGGTCTACAAATG
CGTCGAGGACGATGCGCTGATGGACGAAGCCCGCGCGTTGGCGGAAAAGCTCGCCAACGGTCCGACGCTGGCGCTCAAGA
CGATGAAGCAGAATATCGCGCTGGCGATCGACGGCTCGCTGCAGCAGGTGCTGCTCGCCGAGGCGGAGGGCCAGCGCCTG
GCCGGTGCCAGCGAAGACGCGGCGGAAGGCGGCAAAGCCTTTCTCGAGAAGCGCAAGGCCCAGTTTAAGGGTCGCTGA

Upstream 100 bases:

>100_bases
GGGTGGGGTGCCAGCTTGCGTCGGATGTCGCGCTGCCCTTGCCACCGCCGCCCAACCTCGCCAGAGACAGTTGCAAATCG
CTACGTATGGGAGAGCACGC

Downstream 100 bases:

>100_bases
TGCTGTTCTACGACAGCCCGAACCCGGCGCCCAACCCACGCCGGGTGCGCATTTTCGCTGCCGAGAAAGGCATCGAGCTG
CCGAGCAAGCAAGTCTCGAT

Product: enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MDYETIIVERDGPLMTITLNQPERLNAMAPQMADEIGAAFYDLGAGENGARAVLITGAGKGFCSGADLSARGERSALAMN
GGSHLALQNHYNPAISQVLRAPVPVVCAVNGPAAGVGCSLGLAGDFTIAGKSAYFLQAFVNIGLVPDGGSTWLLTRAIGR
ARATRMMMLGEKIGGEQAEEWGLVYKCVEDDALMDEARALAEKLANGPTLALKTMKQNIALAIDGSLQQVLLAEAEGQRL
AGASEDAAEGGKAFLEKRKAQFKGR

Sequences:

>Translated_265_residues
MDYETIIVERDGPLMTITLNQPERLNAMAPQMADEIGAAFYDLGAGENGARAVLITGAGKGFCSGADLSARGERSALAMN
GGSHLALQNHYNPAISQVLRAPVPVVCAVNGPAAGVGCSLGLAGDFTIAGKSAYFLQAFVNIGLVPDGGSTWLLTRAIGR
ARATRMMMLGEKIGGEQAEEWGLVYKCVEDDALMDEARALAEKLANGPTLALKTMKQNIALAIDGSLQQVLLAEAEGQRL
AGASEDAAEGGKAFLEKRKAQFKGR
>Mature_265_residues
MDYETIIVERDGPLMTITLNQPERLNAMAPQMADEIGAAFYDLGAGENGARAVLITGAGKGFCSGADLSARGERSALAMN
GGSHLALQNHYNPAISQVLRAPVPVVCAVNGPAAGVGCSLGLAGDFTIAGKSAYFLQAFVNIGLVPDGGSTWLLTRAIGR
ARATRMMMLGEKIGGEQAEEWGLVYKCVEDDALMDEARALAEKLANGPTLALKTMKQNIALAIDGSLQQVLLAEAEGQRL
AGASEDAAEGGKAFLEKRKAQFKGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=267, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI45643119, Length=220, Percent_Identity=26.8181818181818, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI260275230, Length=220, Percent_Identity=26.8181818181818, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI260274832, Length=220, Percent_Identity=26.8181818181818, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI25453481, Length=261, Percent_Identity=25.2873563218391, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI51538573, Length=261, Percent_Identity=25.2873563218391, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI31542718, Length=251, Percent_Identity=28.6852589641434, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4757968, Length=268, Percent_Identity=24.2537313432836, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI49355787, Length=268, Percent_Identity=24.2537313432836, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI4757966, Length=272, Percent_Identity=26.1029411764706, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI51538581, Length=272, Percent_Identity=26.1029411764706, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI221136756, Length=268, Percent_Identity=24.6268656716418, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI221136753, Length=268, Percent_Identity=24.6268656716418, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI221307494, Length=268, Percent_Identity=24.6268656716418, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI116235487, Length=234, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI70995211, Length=274, Percent_Identity=26.6423357664234, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1787660, Length=263, Percent_Identity=42.9657794676806, Blast_Score=185, Evalue=2e-48,
Organism=Escherichia coli, GI1787659, Length=265, Percent_Identity=35.0943396226415, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI221142681, Length=276, Percent_Identity=32.9710144927536, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788597, Length=268, Percent_Identity=31.7164179104478, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082183, Length=273, Percent_Identity=24.9084249084249, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788682, Length=199, Percent_Identity=26.6331658291457, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=265, Percent_Identity=32.4528301886792, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25145438, Length=246, Percent_Identity=31.3008130081301, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17549921, Length=213, Percent_Identity=28.6384976525822, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17535521, Length=216, Percent_Identity=26.8518518518519, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560910, Length=252, Percent_Identity=24.2063492063492, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=275, Percent_Identity=23.6363636363636, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=227, Percent_Identity=25.1101321585903, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=250, Percent_Identity=28.4, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129971, Length=247, Percent_Identity=33.1983805668016, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24653477, Length=247, Percent_Identity=33.1983805668016, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI19920382, Length=265, Percent_Identity=29.0566037735849, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24654903, Length=240, Percent_Identity=26.6666666666667, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24653139, Length=277, Percent_Identity=28.8808664259928, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357171, Length=212, Percent_Identity=30.188679245283, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922422, Length=273, Percent_Identity=26.007326007326, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27711; Mature: 27711

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYETIIVERDGPLMTITLNQPERLNAMAPQMADEIGAAFYDLGAGENGARAVLITGAGK
CCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
GFCSGADLSARGERSALAMNGGSHLALQNHYNPAISQVLRAPVPVVCAVNGPAAGVGCSL
CCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCEEE
GLAGDFTIAGKSAYFLQAFVNIGLVPDGGSTWLLTRAIGRARATRMMMLGEKIGGEQAEE
CCCCCEEECCCHHHHHHHHHHCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHH
WGLVYKCVEDDALMDEARALAEKLANGPTLALKTMKQNIALAIDGSLQQVLLAEAEGQRL
CCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEHHCCEEEEECCCHHHHHHHHCCCCCC
AGASEDAAEGGKAFLEKRKAQFKGR
CCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDYETIIVERDGPLMTITLNQPERLNAMAPQMADEIGAAFYDLGAGENGARAVLITGAGK
CCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
GFCSGADLSARGERSALAMNGGSHLALQNHYNPAISQVLRAPVPVVCAVNGPAAGVGCSL
CCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCEEE
GLAGDFTIAGKSAYFLQAFVNIGLVPDGGSTWLLTRAIGRARATRMMMLGEKIGGEQAEE
CCCCCEEECCCHHHHHHHHHHCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHH
WGLVYKCVEDDALMDEARALAEKLANGPTLALKTMKQNIALAIDGSLQQVLLAEAEGQRL
CCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEHHCCEEEEECCCHHHHHHHHCCCCCC
AGASEDAAEGGKAFLEKRKAQFKGR
CCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]