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The map label for this gene is fadE12 [H]

Identifier: 85373761

GI number: 85373761

Start: 965518

End: 966693

Strand: Direct

Name: fadE12 [H]

Synonym: ELI_04670

Alternate gene names: 85373761

Gene position: 965518-966693 (Clockwise)

Preceding gene: 85373758

Following gene: 85373762

Centisome position: 31.63

GC content: 64.8

Gene sequence:

>1176_bases
TTGCTCTTGCCCAACGATTGGCACATCAACCGCGCCGTGCAGACTTTTGCTGTCCATCCTTTCGAAGCGGCGGAAAACGC
GCAAGCCATCCGACAGGACCTGCGCGCCTTCCTCGCCGAGCACCAGCCGCAGGACGATCCGGTCCGCCGCGCCAATTGCT
GGACGGAGTTCGATCCGGCGTTTTCGAAAGCGCTGGGTGCAGCCGGGTATATCGGCATGCTGTGGCCGGAGAACTATGGC
GGTCACGAACGCGGACCGTTGGAGCGCTATATCGTGCTGGAGGAATTGCTGGCAGCGGGCGCACCCGTGGGCGCGCACTG
GATCGCCGATCGCCAGACGGGGCCGCTGCTGCTGCGCTACGGCACCGAAGGGCAGCGCGAGAAATACCTGCCGGGTTTCG
CTGCGGGCACGATGTACGCCTGTATCGGGCTAAGCGAGCCGGGATCGGGCTCCGACTTGGCTTCGGTTCGCACCAGCGCC
CGGCGCACTGACAACGGCTGGGTCATCAACGGCCAGAAGGTCTGGACCACCGGTGCGCACATCAGCCACGCCATGCTCGC
GCTGGTGCGCAGCGAGGAAGGAAGCGAGCGGCAGGCTGGCCTCAGCCAGTTCCTGATCGATCTCGATTTGCCAGGCGTGA
CGATCCGCCCAATCATCGACATGTTCGGCACGCATCATTTCAACGAGGTGTTCTTCGAGGACGTCGAGATACCACATGGC
GCGTTGGTGGGGGCCGAGGGAGAGGGGTGGAAACAGGCGACCGCCGAATTGGCGCTCGAACGCTCGGGGCCGGAACGGTA
CCTCTCCAGCCACGCCTTGCTGGTCGAACTGATCGACAGCGCCGGTCCCGATGCGCCTCCCGAAGTGGTGGCGACCGTCG
GCAGGCTGGTTTCCGAAATGTGGACGTTGCGCCAGATGTCGATGTCGGTCGCAGCCAAGCTGGCCGGCGGGGAGGACCCG
GCGGTGGAAGCCTCCATCGTCAAGGACCTAGGCAATACGTTCGAGCAGGAACTGCCGCTTGCGATCCAGGCCGTCGTCGA
TGCCGATCTCGCCGACGACACCGTGCTGGCAAAGCTGCTGGCGACCTTGCTGCAAGTCTCGCCCAGCTTCTCGCTACGCG
GCGGGACACGCGAAATCCTCCGCGGCATTATCGCGCGCGGACTGGGCCTGAGATGA

Upstream 100 bases:

>100_bases
TGCTTTTCCAGTTTCACGAAATCGCCCACCGGGCCTCTCCTCCTATAGCTTTCGCGCATCCCTAGCACGGCGGCGCGCGC
AGGCCAGCCTTTGTGCCCCC

Downstream 100 bases:

>100_bases
GCGAGAACCGCGACCAGCTCGCCGAAATGGCGGATGGCTTGTTTGCGCAGCTGCGCGGGCAGGATTTCGATCAGGCGTGG
CCGCTATTGGAAGAGGCCGG

Product: Acyl-CoA dehydrogenase, central region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MLLPNDWHINRAVQTFAVHPFEAAENAQAIRQDLRAFLAEHQPQDDPVRRANCWTEFDPAFSKALGAAGYIGMLWPENYG
GHERGPLERYIVLEELLAAGAPVGAHWIADRQTGPLLLRYGTEGQREKYLPGFAAGTMYACIGLSEPGSGSDLASVRTSA
RRTDNGWVINGQKVWTTGAHISHAMLALVRSEEGSERQAGLSQFLIDLDLPGVTIRPIIDMFGTHHFNEVFFEDVEIPHG
ALVGAEGEGWKQATAELALERSGPERYLSSHALLVELIDSAGPDAPPEVVATVGRLVSEMWTLRQMSMSVAAKLAGGEDP
AVEASIVKDLGNTFEQELPLAIQAVVDADLADDTVLAKLLATLLQVSPSFSLRGGTREILRGIIARGLGLR

Sequences:

>Translated_391_residues
MLLPNDWHINRAVQTFAVHPFEAAENAQAIRQDLRAFLAEHQPQDDPVRRANCWTEFDPAFSKALGAAGYIGMLWPENYG
GHERGPLERYIVLEELLAAGAPVGAHWIADRQTGPLLLRYGTEGQREKYLPGFAAGTMYACIGLSEPGSGSDLASVRTSA
RRTDNGWVINGQKVWTTGAHISHAMLALVRSEEGSERQAGLSQFLIDLDLPGVTIRPIIDMFGTHHFNEVFFEDVEIPHG
ALVGAEGEGWKQATAELALERSGPERYLSSHALLVELIDSAGPDAPPEVVATVGRLVSEMWTLRQMSMSVAAKLAGGEDP
AVEASIVKDLGNTFEQELPLAIQAVVDADLADDTVLAKLLATLLQVSPSFSLRGGTREILRGIIARGLGLR
>Mature_391_residues
MLLPNDWHINRAVQTFAVHPFEAAENAQAIRQDLRAFLAEHQPQDDPVRRANCWTEFDPAFSKALGAAGYIGMLWPENYG
GHERGPLERYIVLEELLAAGAPVGAHWIADRQTGPLLLRYGTEGQREKYLPGFAAGTMYACIGLSEPGSGSDLASVRTSA
RRTDNGWVINGQKVWTTGAHISHAMLALVRSEEGSERQAGLSQFLIDLDLPGVTIRPIIDMFGTHHFNEVFFEDVEIPHG
ALVGAEGEGWKQATAELALERSGPERYLSSHALLVELIDSAGPDAPPEVVATVGRLVSEMWTLRQMSMSVAAKLAGGEDP
AVEASIVKDLGNTFEQELPLAIQAVVDADLADDTVLAKLLATLLQVSPSFSLRGGTREILRGIIARGLGLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=243, Percent_Identity=30.8641975308642, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI226958414, Length=223, Percent_Identity=30.9417040358744, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4557233, Length=278, Percent_Identity=30.2158273381295, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI21361497, Length=198, Percent_Identity=31.8181818181818, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI187960098, Length=328, Percent_Identity=26.219512195122, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI4557231, Length=328, Percent_Identity=26.219512195122, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI4501857, Length=236, Percent_Identity=27.1186440677966, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI76496475, Length=256, Percent_Identity=28.515625, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4557235, Length=256, Percent_Identity=28.515625, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI48976061, Length=277, Percent_Identity=28.5198555956679, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI211971008, Length=277, Percent_Identity=28.5198555956679, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4501859, Length=213, Percent_Identity=29.5774647887324, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI7656849, Length=184, Percent_Identity=27.1739130434783, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI38505218, Length=161, Percent_Identity=32.2981366459627, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7669494, Length=123, Percent_Identity=32.520325203252, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4503943, Length=123, Percent_Identity=32.520325203252, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081958, Length=244, Percent_Identity=27.0491803278689, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786223, Length=204, Percent_Identity=26.9607843137255, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=261, Percent_Identity=29.1187739463602, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71990804, Length=212, Percent_Identity=30.6603773584906, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=199, Percent_Identity=31.6582914572864, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=197, Percent_Identity=29.9492385786802, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17506239, Length=210, Percent_Identity=28.0952380952381, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=204, Percent_Identity=29.9019607843137, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=197, Percent_Identity=31.9796954314721, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=204, Percent_Identity=29.9019607843137, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=175, Percent_Identity=34.2857142857143, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=175, Percent_Identity=34.2857142857143, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=187, Percent_Identity=29.4117647058824, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=348, Percent_Identity=27.2988505747126, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17533517, Length=194, Percent_Identity=25.7731958762887, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534353, Length=201, Percent_Identity=26.3681592039801, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982178, Length=195, Percent_Identity=27.6923076923077, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363737, Length=305, Percent_Identity=30.1639344262295, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21355753, Length=259, Percent_Identity=26.6409266409266, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24666513, Length=250, Percent_Identity=28.4, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356377, Length=205, Percent_Identity=27.8048780487805, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646207, Length=257, Percent_Identity=26.4591439688716, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24660351, Length=144, Percent_Identity=31.25, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42372; Mature: 42372

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLPNDWHINRAVQTFAVHPFEAAENAQAIRQDLRAFLAEHQPQDDPVRRANCWTEFDPA
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHH
FSKALGAAGYIGMLWPENYGGHERGPLERYIVLEELLAAGAPVGAHWIADRQTGPLLLRY
HHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHEECCCCCCCEEEEE
GTEGQREKYLPGFAAGTMYACIGLSEPGSGSDLASVRTSARRTDNGWVINGQKVWTTGAH
CCCCCCHHCCCCHHHHHHHHEEECCCCCCCCHHHHHHHHHCCCCCCEEECCCEEEECCHH
ISHAMLALVRSEEGSERQAGLSQFLIDLDLPGVTIRPIIDMFGTHHFNEVFFEDVEIPHG
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCC
ALVGAEGEGWKQATAELALERSGPERYLSSHALLVELIDSAGPDAPPEVVATVGRLVSEM
EEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WTLRQMSMSVAAKLAGGEDPAVEASIVKDLGNTFEQELPLAIQAVVDADLADDTVLAKLL
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHH
ATLLQVSPSFSLRGGTREILRGIIARGLGLR
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLPNDWHINRAVQTFAVHPFEAAENAQAIRQDLRAFLAEHQPQDDPVRRANCWTEFDPA
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHH
FSKALGAAGYIGMLWPENYGGHERGPLERYIVLEELLAAGAPVGAHWIADRQTGPLLLRY
HHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHEECCCCCCCEEEEE
GTEGQREKYLPGFAAGTMYACIGLSEPGSGSDLASVRTSARRTDNGWVINGQKVWTTGAH
CCCCCCHHCCCCHHHHHHHHEEECCCCCCCCHHHHHHHHHCCCCCCEEECCCEEEECCHH
ISHAMLALVRSEEGSERQAGLSQFLIDLDLPGVTIRPIIDMFGTHHFNEVFFEDVEIPHG
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCC
ALVGAEGEGWKQATAELALERSGPERYLSSHALLVELIDSAGPDAPPEVVATVGRLVSEM
EEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WTLRQMSMSVAAKLAGGEDPAVEASIVKDLGNTFEQELPLAIQAVVDADLADDTVLAKLL
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHH
ATLLQVSPSFSLRGGTREILRGIIARGLGLR
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]