Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 85373721

GI number: 85373721

Start: 925009

End: 925500

Strand: Reverse

Name: lspA [H]

Synonym: ELI_04470

Alternate gene names: 85373721

Gene position: 925500-925009 (Counterclockwise)

Preceding gene: 85373732

Following gene: 85373719

Centisome position: 30.32

GC content: 55.89

Gene sequence:

>492_bases
ATGTACCGAAGTCTTGGTCTTTCGATCGCCGTCGCAGTCTTCGCGAGCGATCTCATTTCAAAATGGCTTATTGTGAATGT
GGTCATGGACCCTGCCCGCGTGATAGATGTTTTTCCATTCTTCAATCTGGTGCTCGGATATAATCGCGGTGTTACATTCG
GCCTCCTGAGTTCCGGCAATCCAATCGCGCCCTATTTGCTGTCCGGGTTCGCGCTTCTTGTCGTGGGCGTTCTGGCCAGA
TGGCTCTGGCGCAGTACCGTACGCCTCGAATCCGCCGCGATAGGTTCGATCATTGGCGGTGCATTGGGTAACGTTGCCGA
CCGACTGGCGGACGGAGCGGTCACCGATTTTCTCGACTTCTATGTCGGCGGCTATCACTGGCCGGCGTTCAATCTCGCGG
ATGTCGGAATAGTCCTTGGAGTGGCATTGTTTCTCGTTACCTGGTGGTCCGGAGAAACGCAGCGCGACGATGGCACCGCG
CCGAAAGTGTAG

Upstream 100 bases:

>100_bases
TGACCTCTCTGCATTGACATGATCGATGAGTACCGGGCCCAGACCTGATTTCTATCGTCCAGAGAATCAGAGATATCTGC
CGATCATCCAAGGAACCAAT

Downstream 100 bases:

>100_bases
ATTCTGCGCTTTTGCCAAGGCAATCTTCAGGCGGATTTTCTAGCAAGCCCGCCGATGATGCCGCAGTCGGTGGCAGTGCC
CCCATCGCAGGCCCGTGCCA

Product: putative lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MYRSLGLSIAVAVFASDLISKWLIVNVVMDPARVIDVFPFFNLVLGYNRGVTFGLLSSGNPIAPYLLSGFALLVVGVLAR
WLWRSTVRLESAAIGSIIGGALGNVADRLADGAVTDFLDFYVGGYHWPAFNLADVGIVLGVALFLVTWWSGETQRDDGTA
PKV

Sequences:

>Translated_163_residues
MYRSLGLSIAVAVFASDLISKWLIVNVVMDPARVIDVFPFFNLVLGYNRGVTFGLLSSGNPIAPYLLSGFALLVVGVLAR
WLWRSTVRLESAAIGSIIGGALGNVADRLADGAVTDFLDFYVGGYHWPAFNLADVGIVLGVALFLVTWWSGETQRDDGTA
PKV
>Mature_163_residues
MYRSLGLSIAVAVFASDLISKWLIVNVVMDPARVIDVFPFFNLVLGYNRGVTFGLLSSGNPIAPYLLSGFALLVVGVLAR
WLWRSTVRLESAAIGSIIGGALGNVADRLADGAVTDFLDFYVGGYHWPAFNLADVGIVLGVALFLVTWWSGETQRDDGTA
PKV

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=141, Percent_Identity=38.2978723404255, Blast_Score=81, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17523; Mature: 17523

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRSLGLSIAVAVFASDLISKWLIVNVVMDPARVIDVFPFFNLVLGYNRGVTFGLLSSGN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PIAPYLLSGFALLVVGVLARWLWRSTVRLESAAIGSIIGGALGNVADRLADGAVTDFLDF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVGGYHWPAFNLADVGIVLGVALFLVTWWSGETQRDDGTAPKV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYRSLGLSIAVAVFASDLISKWLIVNVVMDPARVIDVFPFFNLVLGYNRGVTFGLLSSGN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PIAPYLLSGFALLVVGVLARWLWRSTVRLESAAIGSIIGGALGNVADRLADGAVTDFLDF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVGGYHWPAFNLADVGIVLGVALFLVTWWSGETQRDDGTAPKV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]