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The map label for this gene is groES

Identifier: 85373659

GI number: 85373659

Start: 859176

End: 859490

Strand: Reverse

Name: groES

Synonym: ELI_04160

Alternate gene names: 85373659

Gene position: 859490-859176 (Counterclockwise)

Preceding gene: 85373664

Following gene: 85373658

Centisome position: 28.16

GC content: 61.27

Gene sequence:

>315_bases
ATGCATTTTCGACCTTTGCACGATCGCGTGCTGGTTCGCCGTATCGAGGCCGAAGAAAAGACGACCGGCGGCATTATCAT
CCCTGACACCGCCAAGGAAAAGCCGATGGAAGGCGAAGTCGTCGCCGTCGGCCCGGGTGCGCGTGACGATGCCGGGAAGC
TGGTGGAACTCGCCGTCAAGGCGGGCGACCGCATCCTCTTCGGCAAGTGGTCCGGCACCGAAGTGCGGATCGATGGCGAG
GACCTGCTCATCATGAAGGAGAGCGACATCCTCGGCATCATCGAAACCACCGCTGAGCTCAAGAAGGCGGCGTAA

Upstream 100 bases:

>100_bases
TCTTGAAGCCGTTTCCAGCAAAACTAGATCGCGAAGTGCCTCCTGCCGATCATCCGGGGGAGGCGCTGTAAGTCATTTCG
CTTTGTAATGGAGGTTATGC

Downstream 100 bases:

>100_bases
GCACGATACGTTGAGACTTCTGTTCAACCGAAAGAAGCATAGAAGGGAGCAGGCCAAATGGCTGCGAAAGAAGTAAAATT
TGCGTCGGATGCGCGTGATC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein 2; Protein Cpn10 2 [H]

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MHFRPLHDRVLVRRIEAEEKTTGGIIIPDTAKEKPMEGEVVAVGPGARDDAGKLVELAVKAGDRILFGKWSGTEVRIDGE
DLLIMKESDILGIIETTAELKKAA

Sequences:

>Translated_104_residues
MHFRPLHDRVLVRRIEAEEKTTGGIIIPDTAKEKPMEGEVVAVGPGARDDAGKLVELAVKAGDRILFGKWSGTEVRIDGE
DLLIMKESDILGIIETTAELKKAA
>Mature_104_residues
MHFRPLHDRVLVRRIEAEEKTTGGIIIPDTAKEKPMEGEVVAVGPGARDDAGKLVELAVKAGDRILFGKWSGTEVRIDGE
DLLIMKESDILGIIETTAELKKAA

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=90, Percent_Identity=42.2222222222222, Blast_Score=69, Evalue=6e-13,
Organism=Homo sapiens, GI169210012, Length=90, Percent_Identity=40, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=47.9166666666667, Blast_Score=85, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17555568, Length=92, Percent_Identity=46.7391304347826, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324594, Length=91, Percent_Identity=40.6593406593407, Blast_Score=72, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356029, Length=94, Percent_Identity=44.6808510638298, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358317, Length=93, Percent_Identity=45.1612903225806, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 11334; Mature: 11334

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFRPLHDRVLVRRIEAEEKTTGGIIIPDTAKEKPMEGEVVAVGPGARDDAGKLVELAVK
CCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
AGDRILFGKWSGTEVRIDGEDLLIMKESDILGIIETTAELKKAA
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEEECCHHHHHCC
>Mature Secondary Structure
MHFRPLHDRVLVRRIEAEEKTTGGIIIPDTAKEKPMEGEVVAVGPGARDDAGKLVELAVK
CCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
AGDRILFGKWSGTEVRIDGEDLLIMKESDILGIIETTAELKKAA
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]