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The map label for this gene is pgsA [H]

Identifier: 85373616

GI number: 85373616

Start: 814158

End: 814766

Strand: Direct

Name: pgsA [H]

Synonym: ELI_03945

Alternate gene names: 85373616

Gene position: 814158-814766 (Clockwise)

Preceding gene: 85373614

Following gene: 85373620

Centisome position: 26.67

GC content: 63.71

Gene sequence:

>609_bases
ATGCTGACGCTGCCGAACATCCTGACGTTGTCGCGCATTTTCGCTGTGCCGTTGCTGGGCTTCTTCCTCTGGTGGCCCGA
ATGGCAGGTGGGCTATGCGATCGGTTTCGTGCTCTATTGCGTGATCGGCATAACCGATTTCTTCGACGGCTACCTCGCGC
GGGCGCAGGGGACGGTTTCCAAGCTCGGCGTTTTCCTCGATCCGATCGCCGACAAGATCATGGTTGCCGCAGTCATCCTC
GTGCTGACCGCGCAAGGCTACCTTCGAGGGCCGTATGTGGGGGACCTCCACGCGATCGCGGGCCTCGTCATCCTCGTTCG
CGAGATTGCCGTGTCCGGGCTGCGCGAATATCTCGCCGGGCTGCAGGTGTCGGTGCCGGTCACCAAGCTCGCCAAGTGGA
AGACGACACTGCAATTGCTGTCGCTCGGCGCGCTGATTTTGGGCGGGGCAGTGCATGGCCCGCCGCCGGCGACGCTGGCC
GAAGCGAATCTCCGCCTCGCGGACCAGTGGGTGCACCTGATCGGGCTCGCCAGCCTGTGGGGTGCGGCAATCCTGACCCT
CATCACCGGCTGGGATTATCTGCGGGTCGGCCTCAAGCACATGGACTGA

Upstream 100 bases:

>100_bases
CGGCCCTGTTGGCGCCTCGTTCTAGAGCAGACAGAACGGTTGGCAACCACACGCACCATCTTTCTCCGCGCTCCTAGCTG
GGCTAAACGGCGGACCAGCC

Downstream 100 bases:

>100_bases
TCCATCGCGGCAGGAAGGCGCGCGGTCCGGTAGGCGATTCGGGTTGGGAAAACCTCAGCCGTGCAGCGGCAGGCCGAAGC
GATCGCGTGGATCGCCTGCG

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MLTLPNILTLSRIFAVPLLGFFLWWPEWQVGYAIGFVLYCVIGITDFFDGYLARAQGTVSKLGVFLDPIADKIMVAAVIL
VLTAQGYLRGPYVGDLHAIAGLVILVREIAVSGLREYLAGLQVSVPVTKLAKWKTTLQLLSLGALILGGAVHGPPPATLA
EANLRLADQWVHLIGLASLWGAAILTLITGWDYLRVGLKHMD

Sequences:

>Translated_202_residues
MLTLPNILTLSRIFAVPLLGFFLWWPEWQVGYAIGFVLYCVIGITDFFDGYLARAQGTVSKLGVFLDPIADKIMVAAVIL
VLTAQGYLRGPYVGDLHAIAGLVILVREIAVSGLREYLAGLQVSVPVTKLAKWKTTLQLLSLGALILGGAVHGPPPATLA
EANLRLADQWVHLIGLASLWGAAILTLITGWDYLRVGLKHMD
>Mature_202_residues
MLTLPNILTLSRIFAVPLLGFFLWWPEWQVGYAIGFVLYCVIGITDFFDGYLARAQGTVSKLGVFLDPIADKIMVAAVIL
VLTAQGYLRGPYVGDLHAIAGLVILVREIAVSGLREYLAGLQVSVPVTKLAKWKTTLQLLSLGALILGGAVHGPPPATLA
EANLRLADQWVHLIGLASLWGAAILTLITGWDYLRVGLKHMD

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=195, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71984834, Length=112, Percent_Identity=33.9285714285714, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71984838, Length=112, Percent_Identity=33.9285714285714, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320059, Length=169, Percent_Identity=31.9526627218935, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21874; Mature: 21874

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLPNILTLSRIFAVPLLGFFLWWPEWQVGYAIGFVLYCVIGITDFFDGYLARAQGTVS
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
KLGVFLDPIADKIMVAAVILVLTAQGYLRGPYVGDLHAIAGLVILVREIAVSGLREYLAG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
LQVSVPVTKLAKWKTTLQLLSLGALILGGAVHGPPPATLAEANLRLADQWVHLIGLASLW
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GAAILTLITGWDYLRVGLKHMD
HHHHHHHHHCHHHHHHHHHHCC
>Mature Secondary Structure
MLTLPNILTLSRIFAVPLLGFFLWWPEWQVGYAIGFVLYCVIGITDFFDGYLARAQGTVS
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
KLGVFLDPIADKIMVAAVILVLTAQGYLRGPYVGDLHAIAGLVILVREIAVSGLREYLAG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
LQVSVPVTKLAKWKTTLQLLSLGALILGGAVHGPPPATLAEANLRLADQWVHLIGLASLW
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GAAILTLITGWDYLRVGLKHMD
HHHHHHHHHCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA