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The map label for this gene is kup

Identifier: 85373605

GI number: 85373605

Start: 802420

End: 804288

Strand: Direct

Name: kup

Synonym: ELI_03890

Alternate gene names: 85373605

Gene position: 802420-804288 (Clockwise)

Preceding gene: 85373604

Following gene: 85373606

Centisome position: 26.29

GC content: 62.01

Gene sequence:

>1869_bases
ATGGATTCCACCACCAAGCTGGCGATCGGGGCCATCGGCATCGTCTTCGGCGATATCGGCACCAGCCCGCTTTACGCCTT
CCGCGAGACCTTCGTCGGACCCAACCCGCTGCCGATCGACTACAACCACGTCCTCGGCGTCGTCAGCCTGATCTTCTGGT
CGATGACGCTGATCGTGGCGATCCAGTATGTCACCATCCTGATGCGCGCCGACAACAAGGGGCAAGGCGGCAGTCTCGCG
CTCGTGGCTCTCATCAGCCGGAGCGTGCGCAACACCAATTACGGCTGGCTGGTGGTGTTGCTGGGGGTCTTTGCGACGTC
GCTGTTCTACGGCGACAGCATGATTACGCCTGCGATCTCCGTCCTGTCGGCGGTAGAGGGGCTGGTCGTGGTCGACCCCG
AACTGCAGGGCTTCGTCATCCCGATTGCGCTGGTGCTGCTGGTCGGCCTGTTCGTGCTGCAGAAGCGCGGCACCGCGAAG
GTCGGTGCACTCTTTGCTCCGGTAATGATCGTCTATTTCACCGTCATCGCCACGCTGGGCCTGATCTCCATCGTCCAGCA
TCCGGAAATTCTCTACGCGCTCAACCCCTATTACGCGGTGCTGTTCTTCATCAATGACGGGTTTCTGGCCTTCCTAGCGC
TCGGTTCGGTGGTGCTGGCGGTTACGGGGTCCGAAGCGCTCTATTCGGACATGGGCCATTTCGGCCGCGGCCCGATGAAG
CTGAGCTGGTTCGGCTTCGTCATGCCGTGCCTCTTGCTCAATTATTTCGGGCAGGGTGCGATGATCGTCTCGTTAAGCGG
GCCGGAAGCGCAGGAAGCGATCCAGGCACCGTTCTTCCTGCTCGCGCCGGAGATGCTGCGCCTGCCGCTGGTGATTCTCG
CGACCTTCGCCACATTCATCGCCAGCCAGGCGGTGATCAGCGGTGCATTCTCGATCACCCATCAGGCCATCCAGCTCGGC
TTCGTGCCGCGCCTCTCCGTCCGCCACACCAGCGATGCCCATTCGGGCCAGATCTACATTCCCGTCATCAACTGGGCGCT
GATGGTGGCGGTGATCCTGCTGGTGCTGACCTTCCAGAACTCGTCCAATCTCGCCAGCGCCTACGGCATCGCGGTAACCG
GCGCGGTCACGATCGATACGCTGCTGATGGCAGTGCTGCTGGTCGGGGTGTGGAAATGGAAATGGTACTACGCCGCGCCG
GTGGTGATCGTCTTCCTGATCATCGACGGGGCCTATTTCGCCGCCAACCTCACCAAGGTGCCCGACGGCGGCTGGTTCCC
GCTGGTGGTCGGCCTGATCGTCTTCACCCTGCTCACCACCTGGGCGCGCGGCCGGAAGCTGATGCGAGAACGGATGAGCG
AAGTCGCGCTGCCGATCGAAATCTTCGCCAAGAGCGCGCACAACAGCGCCACCCGCGTGCCGGGCACCGCGATCTTCATG
GCCTCCAGCACCGCAGGCGTTCCCTCCGCGCTGCTGCACAACATCAAGCACAACAAGGTGCTGCACGAACGCGTGGTGAT
CCTGACGGTGGAGATATCCGACATCCCCTATGTCGATCCTGCCAAACGCTGCGAATATTCGGAGATCGGCCAGGGCATCT
ACCGCGCGATCCTGCACTATGGCTTCATGGAAGAAACCAACGTACCCGAAGGGCTCAAGTCGATGCAGCAATGCGGCGGC
GAGTTCGACATGATGCAGACCAGTTTCTTCCTCAGCCGCCAGACCCTGTTGCCGAGCGACAAGCCCGGCATGCCGATCTG
GCGCGAGAAGATCTTTGCATGGATGCTGCGCAATGCGGCGACGGCGATGGAGTTCTTCGGGCTGCCCACGAACCGCGTGG
TGGAGCTTGGGAGCCAGGTGCGGATTTAG

Upstream 100 bases:

>100_bases
TGCACAGTGCGCATCCAGCCATGGGATCGGATAGACCGAGAATATGAGCGAAGCTTCTCCATCTGTTGACCGCGCGCCTC
CGGGTGCCGGCGATCAGCAC

Downstream 100 bases:

>100_bases
GAGTCCTTGCCCAAAACCGATAACCCGTCATCCCAGCGAAAGCTGGGATCTTTGTCGGCTCAGTGCTACCTCACAGGATG
ATGGGAGGCTGGGTCTACAT

Product: K+ transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MDSTTKLAIGAIGIVFGDIGTSPLYAFRETFVGPNPLPIDYNHVLGVVSLIFWSMTLIVAIQYVTILMRADNKGQGGSLA
LVALISRSVRNTNYGWLVVLLGVFATSLFYGDSMITPAISVLSAVEGLVVVDPELQGFVIPIALVLLVGLFVLQKRGTAK
VGALFAPVMIVYFTVIATLGLISIVQHPEILYALNPYYAVLFFINDGFLAFLALGSVVLAVTGSEALYSDMGHFGRGPMK
LSWFGFVMPCLLLNYFGQGAMIVSLSGPEAQEAIQAPFFLLAPEMLRLPLVILATFATFIASQAVISGAFSITHQAIQLG
FVPRLSVRHTSDAHSGQIYIPVINWALMVAVILLVLTFQNSSNLASAYGIAVTGAVTIDTLLMAVLLVGVWKWKWYYAAP
VVIVFLIIDGAYFAANLTKVPDGGWFPLVVGLIVFTLLTTWARGRKLMRERMSEVALPIEIFAKSAHNSATRVPGTAIFM
ASSTAGVPSALLHNIKHNKVLHERVVILTVEISDIPYVDPAKRCEYSEIGQGIYRAILHYGFMEETNVPEGLKSMQQCGG
EFDMMQTSFFLSRQTLLPSDKPGMPIWREKIFAWMLRNAATAMEFFGLPTNRVVELGSQVRI

Sequences:

>Translated_622_residues
MDSTTKLAIGAIGIVFGDIGTSPLYAFRETFVGPNPLPIDYNHVLGVVSLIFWSMTLIVAIQYVTILMRADNKGQGGSLA
LVALISRSVRNTNYGWLVVLLGVFATSLFYGDSMITPAISVLSAVEGLVVVDPELQGFVIPIALVLLVGLFVLQKRGTAK
VGALFAPVMIVYFTVIATLGLISIVQHPEILYALNPYYAVLFFINDGFLAFLALGSVVLAVTGSEALYSDMGHFGRGPMK
LSWFGFVMPCLLLNYFGQGAMIVSLSGPEAQEAIQAPFFLLAPEMLRLPLVILATFATFIASQAVISGAFSITHQAIQLG
FVPRLSVRHTSDAHSGQIYIPVINWALMVAVILLVLTFQNSSNLASAYGIAVTGAVTIDTLLMAVLLVGVWKWKWYYAAP
VVIVFLIIDGAYFAANLTKVPDGGWFPLVVGLIVFTLLTTWARGRKLMRERMSEVALPIEIFAKSAHNSATRVPGTAIFM
ASSTAGVPSALLHNIKHNKVLHERVVILTVEISDIPYVDPAKRCEYSEIGQGIYRAILHYGFMEETNVPEGLKSMQQCGG
EFDMMQTSFFLSRQTLLPSDKPGMPIWREKIFAWMLRNAATAMEFFGLPTNRVVELGSQVRI
>Mature_622_residues
MDSTTKLAIGAIGIVFGDIGTSPLYAFRETFVGPNPLPIDYNHVLGVVSLIFWSMTLIVAIQYVTILMRADNKGQGGSLA
LVALISRSVRNTNYGWLVVLLGVFATSLFYGDSMITPAISVLSAVEGLVVVDPELQGFVIPIALVLLVGLFVLQKRGTAK
VGALFAPVMIVYFTVIATLGLISIVQHPEILYALNPYYAVLFFINDGFLAFLALGSVVLAVTGSEALYSDMGHFGRGPMK
LSWFGFVMPCLLLNYFGQGAMIVSLSGPEAQEAIQAPFFLLAPEMLRLPLVILATFATFIASQAVISGAFSITHQAIQLG
FVPRLSVRHTSDAHSGQIYIPVINWALMVAVILLVLTFQNSSNLASAYGIAVTGAVTIDTLLMAVLLVGVWKWKWYYAAP
VVIVFLIIDGAYFAANLTKVPDGGWFPLVVGLIVFTLLTTWARGRKLMRERMSEVALPIEIFAKSAHNSATRVPGTAIFM
ASSTAGVPSALLHNIKHNKVLHERVVILTVEISDIPYVDPAKRCEYSEIGQGIYRAILHYGFMEETNVPEGLKSMQQCGG
EFDMMQTSFFLSRQTLLPSDKPGMPIWREKIFAWMLRNAATAMEFFGLPTNRVVELGSQVRI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=627, Percent_Identity=46.5709728867624, Blast_Score=572, Evalue=1e-164,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_ERYLH (Q2NBS1)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457667.1
- STRING:   Q2NBS1
- GeneID:   3870545
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_03890
- NMPDR:   fig|314225.3.peg.2300
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   ETINIPR
- PhylomeDB:   Q2NBS1
- ProtClustDB:   CLSK835383
- BioCyc:   ELIT314225:ELI_03890-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 67823; Mature: 67823

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13b906b4)-; HASH(0x13d28144)-; HASH(0x12267264)-; HASH(0x1311039c)-; HASH(0x14071ad0)-; HASH(0x13096c98)-; HASH(0x14070c54)-; HASH(0x1338bdfc)-; HASH(0x1407c6c0)-; HASH(0x134806f8)-; HASH(0x13c72ce0)-; HASH(0x14110be4)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTTKLAIGAIGIVFGDIGTSPLYAFRETFVGPNPLPIDYNHVLGVVSLIFWSMTLIVA
CCCCHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IQYVTILMRADNKGQGGSLALVALISRSVRNTNYGWLVVLLGVFATSLFYGDSMITPAIS
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
VLSAVEGLVVVDPELQGFVIPIALVLLVGLFVLQKRGTAKVGALFAPVMIVYFTVIATLG
HHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LISIVQHPEILYALNPYYAVLFFINDGFLAFLALGSVVLAVTGSEALYSDMGHFGRGPMK
HHHHHCCCCEEEEECHHEEEEEEECCHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCCCE
LSWFGFVMPCLLLNYFGQGAMIVSLSGPEAQEAIQAPFFLLAPEMLRLPLVILATFATFI
EHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHH
ASQAVISGAFSITHQAIQLGFVPRLSVRHTSDAHSGQIYIPVINWALMVAVILLVLTFQN
HHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCC
SSNLASAYGIAVTGAVTIDTLLMAVLLVGVWKWKWYYAAPVVIVFLIIDGAYFAANLTKV
CCCCHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
PDGGWFPLVVGLIVFTLLTTWARGRKLMRERMSEVALPIEIFAKSAHNSATRVPGTAIFM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEE
ASSTAGVPSALLHNIKHNKVLHERVVILTVEISDIPYVDPAKRCEYSEIGQGIYRAILHY
ECCCCCCHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHH
GFMEETNVPEGLKSMQQCGGEFDMMQTSFFLSRQTLLPSDKPGMPIWREKIFAWMLRNAA
CCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TAMEFFGLPTNRVVELGSQVRI
HHHHHHCCCHHHHHHCCCCCCH
>Mature Secondary Structure
MDSTTKLAIGAIGIVFGDIGTSPLYAFRETFVGPNPLPIDYNHVLGVVSLIFWSMTLIVA
CCCCHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IQYVTILMRADNKGQGGSLALVALISRSVRNTNYGWLVVLLGVFATSLFYGDSMITPAIS
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
VLSAVEGLVVVDPELQGFVIPIALVLLVGLFVLQKRGTAKVGALFAPVMIVYFTVIATLG
HHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LISIVQHPEILYALNPYYAVLFFINDGFLAFLALGSVVLAVTGSEALYSDMGHFGRGPMK
HHHHHCCCCEEEEECHHEEEEEEECCHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCCCE
LSWFGFVMPCLLLNYFGQGAMIVSLSGPEAQEAIQAPFFLLAPEMLRLPLVILATFATFI
EHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHH
ASQAVISGAFSITHQAIQLGFVPRLSVRHTSDAHSGQIYIPVINWALMVAVILLVLTFQN
HHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCC
SSNLASAYGIAVTGAVTIDTLLMAVLLVGVWKWKWYYAAPVVIVFLIIDGAYFAANLTKV
CCCCHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
PDGGWFPLVVGLIVFTLLTTWARGRKLMRERMSEVALPIEIFAKSAHNSATRVPGTAIFM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEE
ASSTAGVPSALLHNIKHNKVLHERVVILTVEISDIPYVDPAKRCEYSEIGQGIYRAILHY
ECCCCCCHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHH
GFMEETNVPEGLKSMQQCGGEFDMMQTSFFLSRQTLLPSDKPGMPIWREKIFAWMLRNAA
CCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TAMEFFGLPTNRVVELGSQVRI
HHHHHHCCCHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA