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The map label for this gene is fabZ

Identifier: 85373592

GI number: 85373592

Start: 792996

End: 793451

Strand: Direct

Name: fabZ

Synonym: ELI_03825

Alternate gene names: 85373592

Gene position: 792996-793451 (Clockwise)

Preceding gene: 85373591

Following gene: 85373593

Centisome position: 25.98

GC content: 62.5

Gene sequence:

>456_bases
ATGAGCGAACAGGGTTCGTATGACATCCAGCAGGTGCTGAAAGCGCTGCCGCATCGCTATCCGCTGCTCCTGGTCGACCG
GGTCAAGTCGATGGATTTGGGGGAACGCATCCACGCCGTCAAAGGCGTGACGATGAACGAAGAGTTCTTCCAGGGCCATT
TCCCCGGCGCGCCGATCATGCCCGGCGTCCTGCAGGTGGAAGCGATGGCGCAGGCCGCCGCGATCCTCGGCATCGAGACA
CTGGAACTGGCCGGGACCGGCAAGCTGGTGTTCTTCATGGGCATCGAGAATGCCAAGTTCCGCAAGCCCGTGACGCCCGG
GTGCCTGCTCGACCTCGAAGTCGAATTCACCCAGAAGCGCAGCCGCGTCTACAAGTTCAGGGGCAAGGCGAGCGTGGAAG
GCGTGACGACCAGCGAGGCGGAATTTACGGCGATGATCGCGGATCCTCCAGCGTGA

Upstream 100 bases:

>100_bases
CAGCAGGCCCGCGCGCAGGCGGCCCAGGGTGGCCAGCAGCCGGCCCCGGCGCAGCAGCAGCCCACCGGTCGCTAAACCTC
AGCGCGACGGGGGCAGCGGT

Downstream 100 bases:

>100_bases
GTTTTTTGTTTTGCGCACCCCATCCGGGTTGCGATATCCTCGCTCAAGGGGCCTGACGGCCCAATCGCTGCGGGCGCGCA
GTCGCGCTTGCGGTCGGCTG

Product: (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MSEQGSYDIQQVLKALPHRYPLLLVDRVKSMDLGERIHAVKGVTMNEEFFQGHFPGAPIMPGVLQVEAMAQAAAILGIET
LELAGTGKLVFFMGIENAKFRKPVTPGCLLDLEVEFTQKRSRVYKFRGKASVEGVTTSEAEFTAMIADPPA

Sequences:

>Translated_151_residues
MSEQGSYDIQQVLKALPHRYPLLLVDRVKSMDLGERIHAVKGVTMNEEFFQGHFPGAPIMPGVLQVEAMAQAAAILGIET
LELAGTGKLVFFMGIENAKFRKPVTPGCLLDLEVEFTQKRSRVYKFRGKASVEGVTTSEAEFTAMIADPPA
>Mature_150_residues
SEQGSYDIQQVLKALPHRYPLLLVDRVKSMDLGERIHAVKGVTMNEEFFQGHFPGAPIMPGVLQVEAMAQAAAILGIETL
ELAGTGKLVFFMGIENAKFRKPVTPGCLLDLEVEFTQKRSRVYKFRGKASVEGVTTSEAEFTAMIADPPA

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=135, Percent_Identity=47.4074074074074, Blast_Score=132, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_ERYLH (Q2NBT4)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457654.1
- ProteinModelPortal:   Q2NBT4
- SMR:   Q2NBT4
- STRING:   Q2NBT4
- GeneID:   3871406
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_03825
- NMPDR:   fig|314225.3.peg.2313
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   EFTQKRS
- PhylomeDB:   Q2NBT4
- ProtClustDB:   CLSK835358
- BioCyc:   ELIT314225:ELI_03825-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.- [C]

Molecular weight: Translated: 16570; Mature: 16438

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: ACT_SITE 53-53

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQGSYDIQQVLKALPHRYPLLLVDRVKSMDLGERIHAVKGVTMNEEFFQGHFPGAPIM
CCCCCCCCHHHHHHHCCCCCCCCEEHHHHCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCC
PGVLQVEAMAQAAAILGIETLELAGTGKLVFFMGIENAKFRKPVTPGCLLDLEVEFTQKR
CCHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEEHHHHHH
SRVYKFRGKASVEGVTTSEAEFTAMIADPPA
HHHEEECCCCCCCCEEECCCEEEEEEECCCC
>Mature Secondary Structure 
SEQGSYDIQQVLKALPHRYPLLLVDRVKSMDLGERIHAVKGVTMNEEFFQGHFPGAPIM
CCCCCCCHHHHHHHCCCCCCCCEEHHHHCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCC
PGVLQVEAMAQAAAILGIETLELAGTGKLVFFMGIENAKFRKPVTPGCLLDLEVEFTQKR
CCHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEEHHHHHH
SRVYKFRGKASVEGVTTSEAEFTAMIADPPA
HHHEEECCCCCCCCEEECCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA