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The map label for this gene is glpD

Identifier: 85373529

GI number: 85373529

Start: 723834

End: 725327

Strand: Reverse

Name: glpD

Synonym: ELI_03510

Alternate gene names: 85373529

Gene position: 725327-723834 (Counterclockwise)

Preceding gene: 85373530

Following gene: 85373528

Centisome position: 23.76

GC content: 61.65

Gene sequence:

>1494_bases
TTGAGCAACCCATACGACTTGTTGATCATCGGCGGTGGTATCAACGGAGCCGGAATTGCCCGGGACGCGGCCGGTCGGGG
AGCAAAGGTTCTGCTGGTTGAGAAAGACGACCTCGCCCAGCACACGTCATCGGCGAGTACCAAACTGATCCATGGCGGCC
TGCGCTACCTCGAACATTACGAATTCCGTCTGGTTCGCGAAGCTCTCATAGAGCGCGAACGCCTTCTGCAGATTGCACCG
CATATCGTATGGCCGCTGCGCTTCGTCCTGCCGCACGACGAAGGGTTGCGACCGAAATGGATTCTGCGGCTCGGCCTGTT
TCTCTACGACCACCTGGGCGGGCGCAAGATTTTGCCGCCGACCCGTACGATCGATCTGCACGCGCCCCCGCACGGCGATG
TGCTGAAAGACAGGCTGGTCTCAGGCTTCGAATATTCGGACTGCTGGGTAGAAGATTCACGGCTGGTCGTTCTCAATGCG
GTCGGTGCAGCCGAGCGCGGAGCGGATGTCCGCACGCGAACCGAATGTACAGCCTTGGAGCGCGGCGGCGAAGTGTGGAC
TGCGACCGTTCGATCGTCCGACGGCGAGGAGCAGACCGTCCAGGCGAAAGTGGTGATCAACTCGGCCGGGCCATGGGTCG
ATGCCGTCCTCGGCCTCGCCCAACCGGGGCGCAACCATGCCAATCTCCGGCTGGTCAAGGGCAGCCACCTGATCTTCCCG
AAGCTATTCGATCACGACATCTGCTATATCTTCCAGAACAAGGATAACCGGATCGTCTTCGCGATTCCGTACGAGCGTGA
ATTCACGCTCGTCGGTACGACCGATGTCGCGTTCACCGGCGACCCGGACACGATCGCCATCTCGGACGAGGAGAGCCGCT
ACATCTGCGATGCGGTGAACGAGTATCTCCGCGTGGACGTCAGTCCAGGGCAAGCCGTCTCGAGCTATTCCGGCGTGCGC
CCCCTGTACGAGGACCAGGCAGCGGACAATTCCACCGTCACGCGCGACTATGTTTTCGAACTCGACAATGAGGGCGGCGG
GCCGCCGATCCTGTCGATCTTCGGCGGCAAGATCACAACCTATCGCAAGCTCGCCGAACACGCGCTTGAAAAACTTGAAA
TTTCAGGGGCATCGTGGACGGCCGAGAAGCCCCTTCCCGGCGGCGAAATAGCGGTCGGCGGGTTCGAAGCGTTCGTCGTG
CGCATGATGGATCGGTACCCGTTCCTGCCGCAATCGACCGTTGTCCGGCTGTGCCGCGCATATGGCTCGCTCGTTGCGGA
AGTACTGGGTGAGGCGGCTTCCACGCAGGCACTGGGCGAAGAAGTCGCACCGGGCCTCTTCGAAGCCGAACTGCATTATC
TCGTCGAGCGCGAATTTGCTCGCACCGCAGAAGATGTCCTGTGGCGGAGGAGCAAGCTCGGCCTACATCTCGACTCCGAA
GCGCAGAACCGCGTCGCGGCCTGGTTCGCCCGCCGCGAGGTTGAGCCTGCGTGA

Upstream 100 bases:

>100_bases
AGATATCGACCTTTACGGGATCGGCGCTGATGGACTACGGGCTGCAACTTCCGCAGTCGCTGCCAGACACCTGCCTGATC
TATCACCTGAAAGAAGAGCG

Downstream 100 bases:

>100_bases
GCAATGCGCTGTCCGCCATCGGCAGCGACGCTTCGGGCCGCGCGGTCCACCGGCGCGAAGTCATCAAAGCGGATGGCCGC
ATGCTACGCCTCTACGGGCA

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 496

Protein sequence:

>497_residues
MSNPYDLLIIGGGINGAGIARDAAGRGAKVLLVEKDDLAQHTSSASTKLIHGGLRYLEHYEFRLVREALIERERLLQIAP
HIVWPLRFVLPHDEGLRPKWILRLGLFLYDHLGGRKILPPTRTIDLHAPPHGDVLKDRLVSGFEYSDCWVEDSRLVVLNA
VGAAERGADVRTRTECTALERGGEVWTATVRSSDGEEQTVQAKVVINSAGPWVDAVLGLAQPGRNHANLRLVKGSHLIFP
KLFDHDICYIFQNKDNRIVFAIPYEREFTLVGTTDVAFTGDPDTIAISDEESRYICDAVNEYLRVDVSPGQAVSSYSGVR
PLYEDQAADNSTVTRDYVFELDNEGGGPPILSIFGGKITTYRKLAEHALEKLEISGASWTAEKPLPGGEIAVGGFEAFVV
RMMDRYPFLPQSTVVRLCRAYGSLVAEVLGEAASTQALGEEVAPGLFEAELHYLVEREFARTAEDVLWRRSKLGLHLDSE
AQNRVAAWFARREVEPA

Sequences:

>Translated_497_residues
MSNPYDLLIIGGGINGAGIARDAAGRGAKVLLVEKDDLAQHTSSASTKLIHGGLRYLEHYEFRLVREALIERERLLQIAP
HIVWPLRFVLPHDEGLRPKWILRLGLFLYDHLGGRKILPPTRTIDLHAPPHGDVLKDRLVSGFEYSDCWVEDSRLVVLNA
VGAAERGADVRTRTECTALERGGEVWTATVRSSDGEEQTVQAKVVINSAGPWVDAVLGLAQPGRNHANLRLVKGSHLIFP
KLFDHDICYIFQNKDNRIVFAIPYEREFTLVGTTDVAFTGDPDTIAISDEESRYICDAVNEYLRVDVSPGQAVSSYSGVR
PLYEDQAADNSTVTRDYVFELDNEGGGPPILSIFGGKITTYRKLAEHALEKLEISGASWTAEKPLPGGEIAVGGFEAFVV
RMMDRYPFLPQSTVVRLCRAYGSLVAEVLGEAASTQALGEEVAPGLFEAELHYLVEREFARTAEDVLWRRSKLGLHLDSE
AQNRVAAWFARREVEPA
>Mature_496_residues
SNPYDLLIIGGGINGAGIARDAAGRGAKVLLVEKDDLAQHTSSASTKLIHGGLRYLEHYEFRLVREALIERERLLQIAPH
IVWPLRFVLPHDEGLRPKWILRLGLFLYDHLGGRKILPPTRTIDLHAPPHGDVLKDRLVSGFEYSDCWVEDSRLVVLNAV
GAAERGADVRTRTECTALERGGEVWTATVRSSDGEEQTVQAKVVINSAGPWVDAVLGLAQPGRNHANLRLVKGSHLIFPK
LFDHDICYIFQNKDNRIVFAIPYEREFTLVGTTDVAFTGDPDTIAISDEESRYICDAVNEYLRVDVSPGQAVSSYSGVRP
LYEDQAADNSTVTRDYVFELDNEGGGPPILSIFGGKITTYRKLAEHALEKLEISGASWTAEKPLPGGEIAVGGFEAFVVR
MMDRYPFLPQSTVVRLCRAYGSLVAEVLGEAASTQALGEEVAPGLFEAELHYLVEREFARTAEDVLWRRSKLGLHLDSEA
QNRVAAWFARREVEPA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=509, Percent_Identity=32.6129666011788, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI285002231, Length=509, Percent_Identity=32.6129666011788, Blast_Score=201, Evalue=1e-51,
Organism=Escherichia coli, GI2367226, Length=465, Percent_Identity=46.6666666666667, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1788574, Length=393, Percent_Identity=30.7888040712468, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115534726, Length=516, Percent_Identity=30.4263565891473, Blast_Score=175, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17509253, Length=513, Percent_Identity=31.1890838206628, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322036, Length=562, Percent_Identity=28.4697508896797, Blast_Score=156, Evalue=6e-39,
Organism=Drosophila melanogaster, GI161077125, Length=510, Percent_Identity=30.9803921568627, Blast_Score=175, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24653942, Length=510, Percent_Identity=30.9803921568627, Blast_Score=175, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24653944, Length=510, Percent_Identity=30.9803921568627, Blast_Score=175, Evalue=7e-44,
Organism=Drosophila melanogaster, GI20130025, Length=510, Percent_Identity=30.9803921568627, Blast_Score=175, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24586295, Length=508, Percent_Identity=27.1653543307087, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19921278, Length=509, Percent_Identity=25.9332023575639, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 55025; Mature: 54894

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPYDLLIIGGGINGAGIARDAAGRGAKVLLVEKDDLAQHTSSASTKLIHGGLRYLEHY
CCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHH
EFRLVREALIERERLLQIAPHIVWPLRFVLPHDEGLRPKWILRLGLFLYDHLGGRKILPP
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
TRTIDLHAPPHGDVLKDRLVSGFEYSDCWVEDSRLVVLNAVGAAERGADVRTRTECTALE
CCEEEECCCCCCHHHHHHHHCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHHHHH
RGGEVWTATVRSSDGEEQTVQAKVVINSAGPWVDAVLGLAQPGRNHANLRLVKGSHLIFP
CCCCEEEEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCEEEEEECCEEECC
KLFDHDICYIFQNKDNRIVFAIPYEREFTLVGTTDVAFTGDPDTIAISDEESRYICDAVN
HHCCCCEEEEEECCCCEEEEEECCCCEEEEEECCEEEEECCCCEEEECCCCCCHHHHHHH
EYLRVDVSPGQAVSSYSGVRPLYEDQAADNSTVTRDYVFELDNEGGGPPILSIFGGKITT
HHEEEECCCCCHHHHHCCCCCCHHHCCCCCCCEEEEEEEEECCCCCCCCEEEECCCCHHH
YRKLAEHALEKLEISGASWTAEKPLPGGEIAVGGFEAFVVRMMDRYPFLPQSTVVRLCRA
HHHHHHHHHHHEECCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCCHHHHHHHHHH
YGSLVAEVLGEAASTQALGEEVAPGLFEAELHYLVEREFARTAEDVLWRRSKLGLHLDSE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
AQNRVAAWFARREVEPA
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNPYDLLIIGGGINGAGIARDAAGRGAKVLLVEKDDLAQHTSSASTKLIHGGLRYLEHY
CCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHH
EFRLVREALIERERLLQIAPHIVWPLRFVLPHDEGLRPKWILRLGLFLYDHLGGRKILPP
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
TRTIDLHAPPHGDVLKDRLVSGFEYSDCWVEDSRLVVLNAVGAAERGADVRTRTECTALE
CCEEEECCCCCCHHHHHHHHCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHHHHH
RGGEVWTATVRSSDGEEQTVQAKVVINSAGPWVDAVLGLAQPGRNHANLRLVKGSHLIFP
CCCCEEEEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCEEEEEECCEEECC
KLFDHDICYIFQNKDNRIVFAIPYEREFTLVGTTDVAFTGDPDTIAISDEESRYICDAVN
HHCCCCEEEEEECCCCEEEEEECCCCEEEEEECCEEEEECCCCEEEECCCCCCHHHHHHH
EYLRVDVSPGQAVSSYSGVRPLYEDQAADNSTVTRDYVFELDNEGGGPPILSIFGGKITT
HHEEEECCCCCHHHHHCCCCCCHHHCCCCCCCEEEEEEEEECCCCCCCCEEEECCCCHHH
YRKLAEHALEKLEISGASWTAEKPLPGGEIAVGGFEAFVVRMMDRYPFLPQSTVVRLCRA
HHHHHHHHHHHEECCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCCHHHHHHHHHH
YGSLVAEVLGEAASTQALGEEVAPGLFEAELHYLVEREFARTAEDVLWRRSKLGLHLDSE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
AQNRVAAWFARREVEPA
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]