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The map label for this gene is slyD [H]

Identifier: 85373428

GI number: 85373428

Start: 633411

End: 633821

Strand: Reverse

Name: slyD [H]

Synonym: ELI_03005

Alternate gene names: 85373428

Gene position: 633821-633411 (Counterclockwise)

Preceding gene: 85373429

Following gene: 85373427

Centisome position: 20.76

GC content: 65.21

Gene sequence:

>411_bases
GTGACGATCGACTATGTCCTCAAGCGGGGCGATGGCGAGATCGTCGGTGATACCGCACAGACCGGCCCGCAGGACGTCCA
GCTCGGCAGCGGCCAGATCTTCCCGCAGATCGAAAGCGCGCTGACCGGCATGGAAGTCGGCGACGAAAAGTCGGTCGACA
TTGCCTGCGAAGATGCCTTCGGCCAGCGCCAGGAGCAGCTGGTGATCGACATCCCGCGCGCCAACCTGCCGCCCGAGCCT
GCACCGCAGCCCGGCATGCAGCTGAACGCGCAGACGCCCGAAGGACAGCCGATGGTACTGACCATCCTCGAAGTGGGCGA
CGAAGCGGTGAAGGCCGATGGCAACCACCCGCTTGCGGGCGAAGACGTGACGTTCGATGTCACCCTGCGCGATATCAAGC
AGGCCGCCTGA

Upstream 100 bases:

>100_bases
GCGCATTTCCTGACGGCGCATGGGGCTTTTTGCCTGGTCTGCGCCGCGCACACGAACTTCCAAGAGGTTTTGCATGACTA
CTCCCAATAACGGTGACACC

Downstream 100 bases:

>100_bases
CACCGGATTTCGGCGGGAGGGGCGGCACCGGATGCCGCCTCTCCCCGCCCCTCGAACTCGCGGCAGGCGGCGTTGCGTGA
TACATGGATCGAATGCCGCG

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MTIDYVLKRGDGEIVGDTAQTGPQDVQLGSGQIFPQIESALTGMEVGDEKSVDIACEDAFGQRQEQLVIDIPRANLPPEP
APQPGMQLNAQTPEGQPMVLTILEVGDEAVKADGNHPLAGEDVTFDVTLRDIKQAA

Sequences:

>Translated_136_residues
MTIDYVLKRGDGEIVGDTAQTGPQDVQLGSGQIFPQIESALTGMEVGDEKSVDIACEDAFGQRQEQLVIDIPRANLPPEP
APQPGMQLNAQTPEGQPMVLTILEVGDEAVKADGNHPLAGEDVTFDVTLRDIKQAA
>Mature_135_residues
TIDYVLKRGDGEIVGDTAQTGPQDVQLGSGQIFPQIESALTGMEVGDEKSVDIACEDAFGQRQEQLVIDIPRANLPPEPA
PQPGMQLNAQTPEGQPMVLTILEVGDEAVKADGNHPLAGEDVTFDVTLRDIKQAA

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=135, Percent_Identity=34.8148148148148, Blast_Score=80, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 14480; Mature: 14349

Theoretical pI: Translated: 3.80; Mature: 3.80

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDYVLKRGDGEIVGDTAQTGPQDVQLGSGQIFPQIESALTGMEVGDEKSVDIACEDAF
CCCEEEEECCCCCEECCCCCCCCCCEEECCCCCCHHHHHHHCCCCCCCCCCEEEEECCCC
GQRQEQLVIDIPRANLPPEPAPQPGMQLNAQTPEGQPMVLTILEVGDEAVKADGNHPLAG
CCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEECCCHHEECCCCCCCCC
EDVTFDVTLRDIKQAA
CCEEEEEEHHHHHHCC
>Mature Secondary Structure 
TIDYVLKRGDGEIVGDTAQTGPQDVQLGSGQIFPQIESALTGMEVGDEKSVDIACEDAF
CCEEEEECCCCCEECCCCCCCCCCEEECCCCCCHHHHHHHCCCCCCCCCCEEEEECCCC
GQRQEQLVIDIPRANLPPEPAPQPGMQLNAQTPEGQPMVLTILEVGDEAVKADGNHPLAG
CCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEECCCHHEECCCCCCCCC
EDVTFDVTLRDIKQAA
CCEEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]