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The map label for this gene is kdpE [H]

Identifier: 85373330

GI number: 85373330

Start: 544416

End: 545111

Strand: Reverse

Name: kdpE [H]

Synonym: ELI_02515

Alternate gene names: 85373330

Gene position: 545111-544416 (Counterclockwise)

Preceding gene: 85373331

Following gene: 85373329

Centisome position: 17.86

GC content: 62.07

Gene sequence:

>696_bases
ATGAACATCCTCGTTGTGGATGACGAACCTTCGATCCTCGAAGCACTGCGCCCTGTCCTGGCGGCCCGCGGTTACAGCGT
ACTCACCGCGGGGGACGGCAAGGCCGCGCTCGATGCAATCAAGTCCAACCCGATCGATCTCGTCCTGCTCGACCTCGGCC
TGCCCGATGTGGATGGCAGCGAACTGATCGCGCCGATCAAGCGCAGCGCCGATGCCAGTGTCGTCATCCTTTCGGCACGC
CATCTCGAAGCCGACAAGGTGCGTGCGCTCGACGAGGGTGCCGACGATTACGTCGACAAGCCGTTTGGAACCGACGAGTT
GCTCGCCCGGATCAGGGTCATCGAGCGCCGCCGGGCGATGCTTTCCGGCGCGACACCGACGAAGCTAGTATCCGACGATA
TCGTCTTCGATATCGAGCGCCGCGAACTGACCCTGATGGGTGAGCCTGTGCATCTCTCGCCCAAGGAGTTCGCATTGTTC
GAGGTTCTTGCGCGCAACTCGGGACAGGTGGTGACCCAGCGCCGGTTGATGATTGCCGGATGGGGCAACACCACCGTCGA
TAACCAGTACCTGCGGAGCTACATCTCGCTGTTGCGCGACAAGCTGGAAATCGATCCGTCGGATCCGGAATTGCTGCTGA
CCGAGCCGGGCGTTGGCTATCGCCTGGCGGTGCCACTTTCGCCTGCGGAAGGTTAG

Upstream 100 bases:

>100_bases
GATCGATCGCGATCGAATCGCCCGTCGATGGACAGCACGGCACCCGCGCCACCGTACGGCTCGACCTGGCGCGCGAGCCG
GAACTGCGAGAGGCTGCGGC

Downstream 100 bases:

>100_bases
GCCGGCGGGCACGAAAGTTCTGGGGGAAGGCGTGCCCGCCGGCGCAGGGTGGGTTGTCGGCGGTACAGTGGAAGGGTCGC
CGACATCACCTTGATAGCTG

Product: putative two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNILVVDDEPSILEALRPVLAARGYSVLTAGDGKAALDAIKSNPIDLVLLDLGLPDVDGSELIAPIKRSADASVVILSAR
HLEADKVRALDEGADDYVDKPFGTDELLARIRVIERRRAMLSGATPTKLVSDDIVFDIERRELTLMGEPVHLSPKEFALF
EVLARNSGQVVTQRRLMIAGWGNTTVDNQYLRSYISLLRDKLEIDPSDPELLLTEPGVGYRLAVPLSPAEG

Sequences:

>Translated_231_residues
MNILVVDDEPSILEALRPVLAARGYSVLTAGDGKAALDAIKSNPIDLVLLDLGLPDVDGSELIAPIKRSADASVVILSAR
HLEADKVRALDEGADDYVDKPFGTDELLARIRVIERRRAMLSGATPTKLVSDDIVFDIERRELTLMGEPVHLSPKEFALF
EVLARNSGQVVTQRRLMIAGWGNTTVDNQYLRSYISLLRDKLEIDPSDPELLLTEPGVGYRLAVPLSPAEG
>Mature_231_residues
MNILVVDDEPSILEALRPVLAARGYSVLTAGDGKAALDAIKSNPIDLVLLDLGLPDVDGSELIAPIKRSADASVVILSAR
HLEADKVRALDEGADDYVDKPFGTDELLARIRVIERRRAMLSGATPTKLVSDDIVFDIERRELTLMGEPVHLSPKEFALF
EVLARNSGQVVTQRRLMIAGWGNTTVDNQYLRSYISLLRDKLEIDPSDPELLLTEPGVGYRLAVPLSPAEG

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=43.6936936936937, Blast_Score=170, Evalue=7e-44,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=34.070796460177, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=205, Percent_Identity=35.609756097561, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=33.6283185840708, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=32.4444444444444, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=33.6322869955157, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=30.6306306306306, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=30.6666666666667, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=29.004329004329, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=29.9145299145299, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=28.8888888888889, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=33.7719298245614, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI145693157, Length=106, Percent_Identity=37.7358490566038, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=35.8490566037736, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=37.037037037037, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=112, Percent_Identity=36.6071428571429, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25207; Mature: 25207

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILVVDDEPSILEALRPVLAARGYSVLTAGDGKAALDAIKSNPIDLVLLDLGLPDVDGS
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCCH
ELIAPIKRSADASVVILSARHLEADKVRALDEGADDYVDKPFGTDELLARIRVIERRRAM
HHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHH
LSGATPTKLVSDDIVFDIERRELTLMGEPVHLSPKEFALFEVLARNSGQVVTQRRLMIAG
HCCCCCHHEECCCEEEEEECCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEEE
WGNTTVDNQYLRSYISLLRDKLEIDPSDPELLLTEPGVGYRLAVPLSPAEG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCC
>Mature Secondary Structure
MNILVVDDEPSILEALRPVLAARGYSVLTAGDGKAALDAIKSNPIDLVLLDLGLPDVDGS
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCCH
ELIAPIKRSADASVVILSARHLEADKVRALDEGADDYVDKPFGTDELLARIRVIERRRAM
HHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHH
LSGATPTKLVSDDIVFDIERRELTLMGEPVHLSPKEFALFEVLARNSGQVVTQRRLMIAG
HCCCCCHHEECCCEEEEEECCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEEE
WGNTTVDNQYLRSYISLLRDKLEIDPSDPELLLTEPGVGYRLAVPLSPAEG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]