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The map label for this gene is nudL [H]

Identifier: 85373277

GI number: 85373277

Start: 490362

End: 490961

Strand: Reverse

Name: nudL [H]

Synonym: ELI_02250

Alternate gene names: 85373277

Gene position: 490961-490362 (Counterclockwise)

Preceding gene: 85373278

Following gene: 85373276

Centisome position: 16.08

GC content: 66.0

Gene sequence:

>600_bases
ATGAGCACTTTCTTCGAACGGCTCCAGCGCGTGTTCGACGACGGCCATGGCTATCCGCATCCCGACCTGATCACCGACGA
GCGCTTCGCGGAAGGCAGACCCAAACCTGCCGCCGTCCTGATCCCGGTCGTCGAGCGCGCCGAGCCCGGTGTGATCCTGA
CCCAACGCCCGACCGGGCTGCGCAGCCACCCCGGCCAGGTCGCCTTTCCCGGCGGCAAGATCGACGAGGGCGAAACGCCG
CTCGAGGCCGCCTTGCGCGAAGCGGAGGAAGAGCTTGCCATGCCGCGCGAGAAGGTGCGCGTGATCGGCGCGACCGACAA
TTACATCACCGGCACCGGGTTCGACGTGACGCCCGTCCTCGGCGTTGTCCCGCCCGACCTGCCGCTGGTGCCCAATCCCG
GCGAGGTCGAAAGCTGGTTCGAAGTGCCACTCGCAACCCTGTTCGACCGGTCGAACTACACCGCCAACACGGTGCTATGG
CGCGGGGCCGAGCGGACCTATTACGAGATGCATTACGAAGGCTATCGCATCTGGGGCGTGACCGCGGCGATCATCGCCAA
TCTCGCCCACCGGCTGGAACTGACCGAACTGTTCGATTGA

Upstream 100 bases:

>100_bases
TCAATCGCAGCACCTACGAGCAATTGGCCGAGCATGCGCTCGCGCTGGGCGACGACTGGACCGTGACCAGCCAAGGCGAG
ACCTTTTCGCTGCTGCCCGC

Downstream 100 bases:

>100_bases
GGTTCCTTATCCCGTCTCCGTTCACCCTGAGCTTGTCGAAGGGTCGTACTTTCTTATAGCGCAGGGTTATTAGTGAAGGA
CGGGGCTTGGACAGGCGCAG

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSTFFERLQRVFDDGHGYPHPDLITDERFAEGRPKPAAVLIPVVERAEPGVILTQRPTGLRSHPGQVAFPGGKIDEGETP
LEAALREAEEELAMPREKVRVIGATDNYITGTGFDVTPVLGVVPPDLPLVPNPGEVESWFEVPLATLFDRSNYTANTVLW
RGAERTYYEMHYEGYRIWGVTAAIIANLAHRLELTELFD

Sequences:

>Translated_199_residues
MSTFFERLQRVFDDGHGYPHPDLITDERFAEGRPKPAAVLIPVVERAEPGVILTQRPTGLRSHPGQVAFPGGKIDEGETP
LEAALREAEEELAMPREKVRVIGATDNYITGTGFDVTPVLGVVPPDLPLVPNPGEVESWFEVPLATLFDRSNYTANTVLW
RGAERTYYEMHYEGYRIWGVTAAIIANLAHRLELTELFD
>Mature_198_residues
STFFERLQRVFDDGHGYPHPDLITDERFAEGRPKPAAVLIPVVERAEPGVILTQRPTGLRSHPGQVAFPGGKIDEGETPL
EAALREAEEELAMPREKVRVIGATDNYITGTGFDVTPVLGVVPPDLPLVPNPGEVESWFEVPLATLFDRSNYTANTVLWR
GAERTYYEMHYEGYRIWGVTAAIIANLAHRLELTELFD

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=160, Percent_Identity=31.25, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788115, Length=156, Percent_Identity=47.4358974358974, Blast_Score=114, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17536993, Length=166, Percent_Identity=31.3253012048193, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI18859683, Length=190, Percent_Identity=32.1052631578947, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 22199; Mature: 22068

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFFERLQRVFDDGHGYPHPDLITDERFAEGRPKPAAVLIPVVERAEPGVILTQRPTGL
CCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCEEEEECCCCC
RSHPGQVAFPGGKIDEGETPLEAALREAEEELAMPREKVRVIGATDNYITGTGFDVTPVL
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHEEEEECCCCEEECCCCCCCHHH
GVVPPDLPLVPNPGEVESWFEVPLATLFDRSNYTANTVLWRGAERTYYEMHYEGYRIWGV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCEEEEHH
TAAIIANLAHRLELTELFD
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STFFERLQRVFDDGHGYPHPDLITDERFAEGRPKPAAVLIPVVERAEPGVILTQRPTGL
CHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCEEEEECCCCC
RSHPGQVAFPGGKIDEGETPLEAALREAEEELAMPREKVRVIGATDNYITGTGFDVTPVL
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHEEEEECCCCEEECCCCCCCHHH
GVVPPDLPLVPNPGEVESWFEVPLATLFDRSNYTANTVLWRGAERTYYEMHYEGYRIWGV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCEEEEHH
TAAIIANLAHRLELTELFD
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA