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The map label for this gene is trxB [H]

Identifier: 85373258

GI number: 85373258

Start: 472021

End: 473646

Strand: Reverse

Name: trxB [H]

Synonym: ELI_02155

Alternate gene names: 85373258

Gene position: 473646-472021 (Counterclockwise)

Preceding gene: 85373259

Following gene: 85373254

Centisome position: 15.52

GC content: 62.98

Gene sequence:

>1626_bases
ATGGAAAATTTCGGCGACGAACTCGAAACCATGAAGCGGGTGCCGCTGGCTGACGATCATGTTGCCGCAATCCGCAAGAT
TTCCGTCGAGCGCAGCTACGAGCCGGGCGAGATGGTCAGCGAGGTCGGCGAGCCGATGGATACCTTCATCTACTGCCTCG
AAGGCGAGATAGAGGTGGTCGATCCGTATACGCGAGAACGGCTCATGGACGCATCGGTCGGTCCGACCCAGTTCGTGGGC
GAAATCGGTTTCCTCAATCGCGGCACATGGTTCCTGCCGATGCGCGCGGCTAAGCCGACGAAGACCATCGAAGCCCCGCG
CGAGGCCATGCTCGACCTGATGAGCCGGGTACCCGAACTCTCCGACCACATTATTACCGTCTTCGCAGCGCGCCGCCGCA
AACAGTTCGAGCTCAAGAGCAGCTCCATCAAAGTGATCGGGGCCGATCGCGATCCAGCCGTGCAGCGCGTCGAACGCTTC
CTCGCGCGCAACCGGATCCCCTTCCAGAGCTACGATCTCGACGGATCGGACAAGGAAACGGTCGAGGTCTGCACGCTTAC
CGACCATTCGCCCTCGGTGATCGTCGACAAAGACGAAGTGCTGGAAGATCCGACCCCGCGCAAGGTGGCGCAGCACCTCA
ATCTCGACCTCGACATCTGCAGCCAGCGCGTGTTCGACGTGCTGATCGTCGGCGGCGGGCCGGCGGGCGTGGCGGCCGCG
GTCTATACCGGCGCCGAAGGTCTTTGTGCGCTGGTGGTGGAAGATACCGCCATCGGGGGGCAGGCCGGCACGAGCAGCCG
GATCGAGAACTACATGGGGTTTCCGACCGGGATCAGCGGCACCGACCTCGTCTATCGCGGGCAAATCCAGGCGCTGAAGT
TCGGCACGCGTTTCGCCATGCCGCGCCGGGTGGAGCATCTCGAACGGCGGGACGACGGCCTGTTTTGTGCGACACTCGAC
GATGGCGACGAGGTCTGCGCCAAGGTCGTGTTGGTCAGCACCGGCGTGCAGTATCGCCGCCTGCCGCTGGAACGGCTGGA
GGAATTCGAAGGAGCCGGTGTGTTCTACGCCGCCACAGACATGGAAGCGCGCTTCTGCAACAATACCGAGGCGGTAGTGA
TCGGCGGCGGCAATTCTGCTGGACAGGCGGCAATGTACCTCAGTCGCACGGCGGGCCACGTTCATCTGGTCGTGCGCGGC
GATTCGCTCGCAGAGTCCATGTCGAGCTATCTTACCCAGCGGCTCGAGGCAGACGAGCGGGTGACCATCCACTACAACAC
GCAAGTCACCGCACTGCATGGCGAAGGACACCTCAAAGCAGTGTCGTTTGAAAGCGGGGGCAAAGAGCGCAGGATCGACA
CCCGCGCGCTGTTCATAATGATTGGCGCGGCGCCCAATACCGGCTGGCTCAGCAACCTCGTCGAAACCGACGACAAGGGC
TTCGTGTGCACGGGAAGTTCGGTTGGAAAGCGCTCGCCGTTCGAGACATCCTGCGACGGCATCTACGCGGTCGGGGACGT
CCGCGCAGACTCGGTCAAGCGCGTCGCCAGCGCCGTCGGCGAGGGATCGGTCGTAGTGTCCGAGCTGTGGAGCTACATCG
ACGCACAGGAACGCGAAGTGGCATGA

Upstream 100 bases:

>100_bases
AAAAAGAGGGGCGGCTTCGGTCGCCCCTTTTTGTGACTCGCCCCCGACCCTATCTGGGTCGGATATCGCGAAGACCACGC
ACCAGTGTCAAAGGACGACC

Downstream 100 bases:

>100_bases
TAGCCTCCCGCGCGGGTCAGGCTACTTCTTGCCGAACAAGCCCTTGGCCATTCCCAACACATCGTTGAGCGGATTGCCGT
CACCGTCGCGGTCGAGCATG

Product: putative thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MENFGDELETMKRVPLADDHVAAIRKISVERSYEPGEMVSEVGEPMDTFIYCLEGEIEVVDPYTRERLMDASVGPTQFVG
EIGFLNRGTWFLPMRAAKPTKTIEAPREAMLDLMSRVPELSDHIITVFAARRRKQFELKSSSIKVIGADRDPAVQRVERF
LARNRIPFQSYDLDGSDKETVEVCTLTDHSPSVIVDKDEVLEDPTPRKVAQHLNLDLDICSQRVFDVLIVGGGPAGVAAA
VYTGAEGLCALVVEDTAIGGQAGTSSRIENYMGFPTGISGTDLVYRGQIQALKFGTRFAMPRRVEHLERRDDGLFCATLD
DGDEVCAKVVLVSTGVQYRRLPLERLEEFEGAGVFYAATDMEARFCNNTEAVVIGGGNSAGQAAMYLSRTAGHVHLVVRG
DSLAESMSSYLTQRLEADERVTIHYNTQVTALHGEGHLKAVSFESGGKERRIDTRALFIMIGAAPNTGWLSNLVETDDKG
FVCTGSSVGKRSPFETSCDGIYAVGDVRADSVKRVASAVGEGSVVVSELWSYIDAQEREVA

Sequences:

>Translated_541_residues
MENFGDELETMKRVPLADDHVAAIRKISVERSYEPGEMVSEVGEPMDTFIYCLEGEIEVVDPYTRERLMDASVGPTQFVG
EIGFLNRGTWFLPMRAAKPTKTIEAPREAMLDLMSRVPELSDHIITVFAARRRKQFELKSSSIKVIGADRDPAVQRVERF
LARNRIPFQSYDLDGSDKETVEVCTLTDHSPSVIVDKDEVLEDPTPRKVAQHLNLDLDICSQRVFDVLIVGGGPAGVAAA
VYTGAEGLCALVVEDTAIGGQAGTSSRIENYMGFPTGISGTDLVYRGQIQALKFGTRFAMPRRVEHLERRDDGLFCATLD
DGDEVCAKVVLVSTGVQYRRLPLERLEEFEGAGVFYAATDMEARFCNNTEAVVIGGGNSAGQAAMYLSRTAGHVHLVVRG
DSLAESMSSYLTQRLEADERVTIHYNTQVTALHGEGHLKAVSFESGGKERRIDTRALFIMIGAAPNTGWLSNLVETDDKG
FVCTGSSVGKRSPFETSCDGIYAVGDVRADSVKRVASAVGEGSVVVSELWSYIDAQEREVA
>Mature_541_residues
MENFGDELETMKRVPLADDHVAAIRKISVERSYEPGEMVSEVGEPMDTFIYCLEGEIEVVDPYTRERLMDASVGPTQFVG
EIGFLNRGTWFLPMRAAKPTKTIEAPREAMLDLMSRVPELSDHIITVFAARRRKQFELKSSSIKVIGADRDPAVQRVERF
LARNRIPFQSYDLDGSDKETVEVCTLTDHSPSVIVDKDEVLEDPTPRKVAQHLNLDLDICSQRVFDVLIVGGGPAGVAAA
VYTGAEGLCALVVEDTAIGGQAGTSSRIENYMGFPTGISGTDLVYRGQIQALKFGTRFAMPRRVEHLERRDDGLFCATLD
DGDEVCAKVVLVSTGVQYRRLPLERLEEFEGAGVFYAATDMEARFCNNTEAVVIGGGNSAGQAAMYLSRTAGHVHLVVRG
DSLAESMSSYLTQRLEADERVTIHYNTQVTALHGEGHLKAVSFESGGKERRIDTRALFIMIGAAPNTGWLSNLVETDDKG
FVCTGSSVGKRSPFETSCDGIYAVGDVRADSVKRVASAVGEGSVVVSELWSYIDAQEREVA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=317, Percent_Identity=29.3375394321767, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI87081763, Length=335, Percent_Identity=27.4626865671642, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=29.9382716049383, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321898, Length=327, Percent_Identity=29.0519877675841, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 59188; Mature: 59188

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENFGDELETMKRVPLADDHVAAIRKISVERSYEPGEMVSEVGEPMDTFIYCLEGEIEVV
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHEEEEECCCEEEE
DPYTRERLMDASVGPTQFVGEIGFLNRGTWFLPMRAAKPTKTIEAPREAMLDLMSRVPEL
CCHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCH
SDHIITVFAARRRKQFELKSSSIKVIGADRDPAVQRVERFLARNRIPFQSYDLDGSDKET
HHHHHHHHHHHHHHHEEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
VEVCTLTDHSPSVIVDKDEVLEDPTPRKVAQHLNLDLDICSQRVFDVLIVGGGPAGVAAA
EEEEEECCCCCCEEECHHHHHCCCCHHHHHHHCCCCHHHHHHCEEEEEEECCCCHHHHHH
VYTGAEGLCALVVEDTAIGGQAGTSSRIENYMGFPTGISGTDLVYRGQIQALKFGTRFAM
HHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCEEEEECCHHHCC
PRRVEHLERRDDGLFCATLDDGDEVCAKVVLVSTGVQYRRLPLERLEEFEGAGVFYAATD
CHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHCCCEEEEEECC
MEARFCNNTEAVVIGGGNSAGQAAMYLSRTAGHVHLVVRGDSLAESMSSYLTQRLEADER
CCHHHCCCCCEEEEECCCCCCCHHEEEEECCCEEEEEEECCHHHHHHHHHHHHHHCCCCE
VTIHYNTQVTALHGEGHLKAVSFESGGKERRIDTRALFIMIGAAPNTGWLSNLVETDDKG
EEEEECCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEEEEECCCCCHHHHHHHCCCCCC
FVCTGSSVGKRSPFETSCDGIYAVGDVRADSVKRVASAVGEGSVVVSELWSYIDAQEREV
EEEECCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHCC
A
C
>Mature Secondary Structure
MENFGDELETMKRVPLADDHVAAIRKISVERSYEPGEMVSEVGEPMDTFIYCLEGEIEVV
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHEEEEECCCEEEE
DPYTRERLMDASVGPTQFVGEIGFLNRGTWFLPMRAAKPTKTIEAPREAMLDLMSRVPEL
CCHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCH
SDHIITVFAARRRKQFELKSSSIKVIGADRDPAVQRVERFLARNRIPFQSYDLDGSDKET
HHHHHHHHHHHHHHHEEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
VEVCTLTDHSPSVIVDKDEVLEDPTPRKVAQHLNLDLDICSQRVFDVLIVGGGPAGVAAA
EEEEEECCCCCCEEECHHHHHCCCCHHHHHHHCCCCHHHHHHCEEEEEEECCCCHHHHHH
VYTGAEGLCALVVEDTAIGGQAGTSSRIENYMGFPTGISGTDLVYRGQIQALKFGTRFAM
HHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCEEEEECCHHHCC
PRRVEHLERRDDGLFCATLDDGDEVCAKVVLVSTGVQYRRLPLERLEEFEGAGVFYAATD
CHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHCCCEEEEEECC
MEARFCNNTEAVVIGGGNSAGQAAMYLSRTAGHVHLVVRGDSLAESMSSYLTQRLEADER
CCHHHCCCCCEEEEECCCCCCCHHEEEEECCCEEEEEEECCHHHHHHHHHHHHHHCCCCE
VTIHYNTQVTALHGEGHLKAVSFESGGKERRIDTRALFIMIGAAPNTGWLSNLVETDDKG
EEEEECCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEEEEECCCCCHHHHHHHCCCCCC
FVCTGSSVGKRSPFETSCDGIYAVGDVRADSVKRVASAVGEGSVVVSELWSYIDAQEREV
EEEECCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11353084 [H]