| Definition | Erythrobacter litoralis HTCC2594 chromosome, complete genome. |
|---|---|
| Accession | NC_007722 |
| Length | 3,052,398 |
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The map label for this gene is yqhE [C]
Identifier: 85373223
GI number: 85373223
Start: 440160
End: 440978
Strand: Reverse
Name: yqhE [C]
Synonym: ELI_01980
Alternate gene names: 85373223
Gene position: 440978-440160 (Counterclockwise)
Preceding gene: 85373224
Following gene: 85373220
Centisome position: 14.45
GC content: 62.15
Gene sequence:
>819_bases ATGACCGACTATCCGCTGCTCACGCTCAACGACGACCGCCAGATCCCGCAACTGGGTTTCGGCACCTGGGAGATCGATCC CGAAGACGCCGCCGGGGCGGTGAAGACCGCGCTCGAGGCCGGGTACTGGCTGATCGACACCGCCGCCGTCTATGGCAACG AGAAGGAGGTCGGCGAAGGGATCGGCGATTGGTCGGACATCTTCCTCCAGACGAAAATCTGGAATGAAAGCCAGGGCTAT GACCGCACGCTGAAGGCGGCCGACAAGTGTCTGTCACGGCTTGGCCGCGATCATGTCGACATGCTGCTGATCCACTGGCC CTGCCCGGAGAAGGGTCTGTTCGTGGAGACATGGAAAGCGCTGATCGAACTGCGCGACCAGGGCAAGGCCAAGTCCATCG GCGTGTCCAACTTCCGCGAAGAGGATCTGAAGCGGATCGTCGACGAGACCGGCGTCGTCCCGGCGCTCAACCAGATCGAA CTGCACCCGACTTTCCAGCAGCGCGAGATGCGCAAGCTGCATGACGAAATGGGCATCGTCACGCAAAGCTGGTCGCCGCT CGGCCAGGGCAATGCTTTCGGCAACGAGACCATCGAAGCGATTGCCGAAGAAACCGGGCAGTCTGCGCCGGCCGTGGTGA TCCGCTGGCACATCCAGTGCGGGCTAAGCACTTTGCCGCGCTCGACCAACCCGGACCATATCCGAAGCAATTTCACCGCG CTCGATTTCGAGCTGACCGACGAGCAGATGAAGCGGATCGACGATCTCGACAGCGACGACGGCCGGATGGGCCCGAACCC GGGCGAATTCAACAGCTAG
Upstream 100 bases:
>100_bases CGGTCGCTTCGCCACCCGTAACCTGGGATTCATGGCTGCATCCTGAGACCGGACGGAAACATGCAGCCCCTTCGCTCATT GATGAAGCGAAGGAGACACT
Downstream 100 bases:
>100_bases AGCGCGACCGGCTCGCTGCCGTCGAGCCGGTGCGAGCAGCCCAGCGCGCGCGGATCGTCGCTCTCTTCGAGCGCGGCGAC CGTGCGCCAGGCCTCTTCGC
Product: putative oxidoreductase protein
Products: 2-keto-L-gulonate; NADP [C]
Alternate protein names: NA
Number of amino acids: Translated: 272; Mature: 271
Protein sequence:
>272_residues MTDYPLLTLNDDRQIPQLGFGTWEIDPEDAAGAVKTALEAGYWLIDTAAVYGNEKEVGEGIGDWSDIFLQTKIWNESQGY DRTLKAADKCLSRLGRDHVDMLLIHWPCPEKGLFVETWKALIELRDQGKAKSIGVSNFREEDLKRIVDETGVVPALNQIE LHPTFQQREMRKLHDEMGIVTQSWSPLGQGNAFGNETIEAIAEETGQSAPAVVIRWHIQCGLSTLPRSTNPDHIRSNFTA LDFELTDEQMKRIDDLDSDDGRMGPNPGEFNS
Sequences:
>Translated_272_residues MTDYPLLTLNDDRQIPQLGFGTWEIDPEDAAGAVKTALEAGYWLIDTAAVYGNEKEVGEGIGDWSDIFLQTKIWNESQGY DRTLKAADKCLSRLGRDHVDMLLIHWPCPEKGLFVETWKALIELRDQGKAKSIGVSNFREEDLKRIVDETGVVPALNQIE LHPTFQQREMRKLHDEMGIVTQSWSPLGQGNAFGNETIEAIAEETGQSAPAVVIRWHIQCGLSTLPRSTNPDHIRSNFTA LDFELTDEQMKRIDDLDSDDGRMGPNPGEFNS >Mature_271_residues TDYPLLTLNDDRQIPQLGFGTWEIDPEDAAGAVKTALEAGYWLIDTAAVYGNEKEVGEGIGDWSDIFLQTKIWNESQGYD RTLKAADKCLSRLGRDHVDMLLIHWPCPEKGLFVETWKALIELRDQGKAKSIGVSNFREEDLKRIVDETGVVPALNQIEL HPTFQQREMRKLHDEMGIVTQSWSPLGQGNAFGNETIEAIAEETGQSAPAVVIRWHIQCGLSTLPRSTNPDHIRSNFTAL DFELTDEQMKRIDDLDSDDGRMGPNPGEFNS
Specific function: Reduction [C]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI45446745, Length=300, Percent_Identity=33.6666666666667, Blast_Score=156, Evalue=2e-38, Organism=Homo sapiens, GI4503285, Length=300, Percent_Identity=33.6666666666667, Blast_Score=156, Evalue=2e-38, Organism=Homo sapiens, GI24497577, Length=290, Percent_Identity=29.3103448275862, Blast_Score=155, Evalue=4e-38, Organism=Homo sapiens, GI5174391, Length=290, Percent_Identity=29.3103448275862, Blast_Score=155, Evalue=4e-38, Organism=Homo sapiens, GI310109922, Length=282, Percent_Identity=33.6879432624113, Blast_Score=154, Evalue=8e-38, Organism=Homo sapiens, GI310109920, Length=300, Percent_Identity=33, Blast_Score=153, Evalue=2e-37, Organism=Homo sapiens, GI5453543, Length=300, Percent_Identity=33, Blast_Score=152, Evalue=2e-37, Organism=Homo sapiens, GI223468663, Length=288, Percent_Identity=32.2916666666667, Blast_Score=149, Evalue=3e-36, Organism=Homo sapiens, GI93277124, Length=297, Percent_Identity=31.6498316498317, Blast_Score=147, Evalue=7e-36, Organism=Homo sapiens, GI4502049, Length=282, Percent_Identity=34.0425531914894, Blast_Score=141, Evalue=6e-34, Organism=Homo sapiens, GI291291012, Length=261, Percent_Identity=32.9501915708812, Blast_Score=140, Evalue=2e-33, Organism=Homo sapiens, GI5174695, Length=296, Percent_Identity=30.4054054054054, Blast_Score=139, Evalue=3e-33, Organism=Homo sapiens, GI24497583, Length=300, Percent_Identity=31, Blast_Score=137, Evalue=8e-33, Organism=Homo sapiens, GI24497585, Length=298, Percent_Identity=30.8724832214765, Blast_Score=133, Evalue=2e-31, Organism=Homo sapiens, GI300116273, Length=275, Percent_Identity=29.4545454545455, Blast_Score=121, Evalue=8e-28, Organism=Homo sapiens, GI310109924, Length=150, Percent_Identity=32, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI207028673, Length=130, Percent_Identity=39.2307692307692, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI310109926, Length=130, Percent_Identity=37.6923076923077, Blast_Score=79, Evalue=5e-15, Organism=Escherichia coli, GI87082198, Length=276, Percent_Identity=40.9420289855072, Blast_Score=223, Evalue=8e-60, Organism=Escherichia coli, GI1786400, Length=257, Percent_Identity=34.6303501945525, Blast_Score=154, Evalue=7e-39, Organism=Escherichia coli, GI1788081, Length=277, Percent_Identity=28.8808664259928, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI87081735, Length=217, Percent_Identity=28.110599078341, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI48994888, Length=263, Percent_Identity=25.0950570342205, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17537077, Length=290, Percent_Identity=36.551724137931, Blast_Score=177, Evalue=5e-45, Organism=Caenorhabditis elegans, GI17537075, Length=298, Percent_Identity=35.9060402684564, Blast_Score=176, Evalue=1e-44, Organism=Caenorhabditis elegans, GI17537079, Length=307, Percent_Identity=31.2703583061889, Blast_Score=162, Evalue=2e-40, Organism=Caenorhabditis elegans, GI71998625, Length=269, Percent_Identity=31.5985130111524, Blast_Score=157, Evalue=8e-39, Organism=Caenorhabditis elegans, GI17564128, Length=294, Percent_Identity=30.6122448979592, Blast_Score=154, Evalue=5e-38, Organism=Caenorhabditis elegans, GI17538386, Length=273, Percent_Identity=30.4029304029304, Blast_Score=149, Evalue=2e-36, Organism=Caenorhabditis elegans, GI17552492, Length=260, Percent_Identity=32.3076923076923, Blast_Score=148, Evalue=3e-36, Organism=Caenorhabditis elegans, GI17561298, Length=269, Percent_Identity=30.8550185873606, Blast_Score=143, Evalue=8e-35, Organism=Caenorhabditis elegans, GI17561300, Length=273, Percent_Identity=31.5018315018315, Blast_Score=135, Evalue=2e-32, Organism=Caenorhabditis elegans, GI17566692, Length=290, Percent_Identity=27.5862068965517, Blast_Score=132, Evalue=2e-31, Organism=Caenorhabditis elegans, GI17550248, Length=285, Percent_Identity=27.719298245614, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17562292, Length=285, Percent_Identity=26.3157894736842, Blast_Score=110, Evalue=6e-25, Organism=Saccharomyces cerevisiae, GI6324694, Length=290, Percent_Identity=37.5862068965517, Blast_Score=177, Evalue=2e-45, Organism=Saccharomyces cerevisiae, GI6322556, Length=266, Percent_Identity=34.9624060150376, Blast_Score=172, Evalue=5e-44, Organism=Saccharomyces cerevisiae, GI6320576, Length=290, Percent_Identity=37.5862068965517, Blast_Score=172, Evalue=6e-44, Organism=Saccharomyces cerevisiae, GI6321896, Length=306, Percent_Identity=30.3921568627451, Blast_Score=138, Evalue=9e-34, Organism=Saccharomyces cerevisiae, GI6319625, Length=295, Percent_Identity=31.864406779661, Blast_Score=131, Evalue=9e-32, Organism=Saccharomyces cerevisiae, GI6320079, Length=281, Percent_Identity=30.9608540925267, Blast_Score=110, Evalue=2e-25, Organism=Drosophila melanogaster, GI24657054, Length=280, Percent_Identity=36.7857142857143, Blast_Score=171, Evalue=4e-43, Organism=Drosophila melanogaster, GI24662789, Length=298, Percent_Identity=31.5436241610738, Blast_Score=164, Evalue=8e-41, Organism=Drosophila melanogaster, GI24663317, Length=285, Percent_Identity=31.5789473684211, Blast_Score=159, Evalue=2e-39, Organism=Drosophila melanogaster, GI24644950, Length=303, Percent_Identity=33.003300330033, Blast_Score=158, Evalue=4e-39, Organism=Drosophila melanogaster, GI20129731, Length=272, Percent_Identity=31.6176470588235, Blast_Score=155, Evalue=3e-38, Organism=Drosophila melanogaster, GI221378297, Length=323, Percent_Identity=30.9597523219814, Blast_Score=150, Evalue=7e-37, Organism=Drosophila melanogaster, GI21356425, Length=296, Percent_Identity=32.0945945945946, Blast_Score=149, Evalue=2e-36, Organism=Drosophila melanogaster, GI24662781, Length=297, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=2e-33, Organism=Drosophila melanogaster, GI24662785, Length=297, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=3e-32, Organism=Drosophila melanogaster, GI45553081, Length=288, Percent_Identity=29.1666666666667, Blast_Score=134, Evalue=9e-32, Organism=Drosophila melanogaster, GI281366140, Length=252, Percent_Identity=28.1746031746032, Blast_Score=108, Evalue=3e-24,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: NA
Molecular weight: Translated: 30542; Mature: 30411
Theoretical pI: Translated: 4.34; Mature: 4.34
Prosite motif: PS00062 ALDOKETO_REDUCTASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDYPLLTLNDDRQIPQLGFGTWEIDPEDAAGAVKTALEAGYWLIDTAAVYGNEKEVGEG CCCCCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCEEEEHHHHHCCHHHHHCC IGDWSDIFLQTKIWNESQGYDRTLKAADKCLSRLGRDHVDMLLIHWPCPEKGLFVETWKA CCCHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHH LIELRDQGKAKSIGVSNFREEDLKRIVDETGVVPALNQIELHPTFQQREMRKLHDEMGIV HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCE TQSWSPLGQGNAFGNETIEAIAEETGQSAPAVVIRWHIQCGLSTLPRSTNPDHIRSNFTA ECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCHHHCCCCCCHHHHHCCCEE LDFELTDEQMKRIDDLDSDDGRMGPNPGEFNS EEEEECHHHHHHHHCCCCCCCCCCCCCCCCCC >Mature Secondary Structure TDYPLLTLNDDRQIPQLGFGTWEIDPEDAAGAVKTALEAGYWLIDTAAVYGNEKEVGEG CCCCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCEEEEHHHHHCCHHHHHCC IGDWSDIFLQTKIWNESQGYDRTLKAADKCLSRLGRDHVDMLLIHWPCPEKGLFVETWKA CCCHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHH LIELRDQGKAKSIGVSNFREEDLKRIVDETGVVPALNQIELHPTFQQREMRKLHDEMGIV HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCE TQSWSPLGQGNAFGNETIEAIAEETGQSAPAVVIRWHIQCGLSTLPRSTNPDHIRSNFTA ECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCHHHCCCCCCHHHHHCCCEE LDFELTDEQMKRIDDLDSDDGRMGPNPGEFNS EEEEECHHHHHHHHCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 2,5-diketo-D-gluconate; NADPH [C]
Specific reaction: 2,5-diketo-D-gluconate + NADPH = 2-keto-L-gulonate + NADP [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA