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The map label for this gene is argC2 [H]

Identifier: 85373161

GI number: 85373161

Start: 379968

End: 380903

Strand: Reverse

Name: argC2 [H]

Synonym: ELI_01670

Alternate gene names: 85373161

Gene position: 380903-379968 (Counterclockwise)

Preceding gene: 85373162

Following gene: 85373160

Centisome position: 12.48

GC content: 65.71

Gene sequence:

>936_bases
ATGGCGCGCAGCGTCTTCATCGACGGGGCGGCTGGCACCACCGGGCTCGAAATCCGCCAACGATTGGCCGACCGCACCGA
GTTCGACCTGCTGGTACTGGACGATGCCGATCGCAAGGATGCCGCCAAACGGCGCGAAGCGCTGAACGATAGCGATTTCG
CGATCCTCTGCCTTCCCGATGATGCGGCGGTTGAAGCCGTCGCGATGATCGATCCCGCTAGCAAGACCCGCGTAATCGAC
GCCTCCAGCGCGCATCGGGTGGCCGACGGCTGGACCTATGGCTTTCCGGAGATCGCCGGACGCGAAGCGGTCGCAACGGC
GCGGTTCGTCAGCAATCCCGGATGCTACCCGACCGGCTTCATCGGCCTGGTTGCGCCGCTCGTCCGCACCGGGCTGTTGC
CGCATGACTGGCCTTTCACCTGCAACGCCGTGAGCGGCTATTCCGGCGGCGGCAAGGCGTTGATCGAGCGTTTCGAGGGC
ACGGGAGCCGACATCGCATTTCGCACCTACGGTCTCGAGCTGTCGCATAAGCACCGGCCCGAGATGCAACAGCACGCCGG
ACTCGAGCATGGCGTGCTGTTCGCGCCGTCGGTCGTGCCCGCGTTCCGCGGCATGGTGGTGGAGGTGCCGCTGCATCTCG
GCGCAATGGCGACCGGCCCGCATTCGGATGCGCTGCGCGAAGCGTTGCAATCGTTCTACCAGGGATCGCCCGTGGTCACG
GTCGCTTCCGGCGTTGCACCGGGCGAATTGCTGCTGCATCGTCAGGAACAGCCGAGCGACACGTTGACGCTGCATGTCTG
TGGCAACGAGGGTGGCTGGAATGTCCGCCTGGTCGCCGTGCTCGACAATCTCGGCAAGGGCGCGAGCGGTGCGGCGGTAC
AAAACCTCAATCTCATGGCCGGACTCGACGAGACCGCGGGGCTGCGGCTGACTTGA

Upstream 100 bases:

>100_bases
ACGGCTTCGAAGCGCTGGATGTGTCGGACAATTGGGTGTGGGGCGCCTGCGGTCCTGAAGGTCCGAGCGGCTACGTGACC
CGCACCGCTTTCGACATCTG

Downstream 100 bases:

>100_bases
CTATACTGCCTAAATTTTAAGCATGACCGCCCAGCACTTGGGCAGCCATCTCCCCCGAACTGCCTGGCGCCTCTTCCCCG
TCTTAGCCTTCTGCCCTAGG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR 2; N-acetyl-glutamate semialdehyde dehydrogenase 2; NAGSA dehydrogenase 2 [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MARSVFIDGAAGTTGLEIRQRLADRTEFDLLVLDDADRKDAAKRREALNDSDFAILCLPDDAAVEAVAMIDPASKTRVID
ASSAHRVADGWTYGFPEIAGREAVATARFVSNPGCYPTGFIGLVAPLVRTGLLPHDWPFTCNAVSGYSGGGKALIERFEG
TGADIAFRTYGLELSHKHRPEMQQHAGLEHGVLFAPSVVPAFRGMVVEVPLHLGAMATGPHSDALREALQSFYQGSPVVT
VASGVAPGELLLHRQEQPSDTLTLHVCGNEGGWNVRLVAVLDNLGKGASGAAVQNLNLMAGLDETAGLRLT

Sequences:

>Translated_311_residues
MARSVFIDGAAGTTGLEIRQRLADRTEFDLLVLDDADRKDAAKRREALNDSDFAILCLPDDAAVEAVAMIDPASKTRVID
ASSAHRVADGWTYGFPEIAGREAVATARFVSNPGCYPTGFIGLVAPLVRTGLLPHDWPFTCNAVSGYSGGGKALIERFEG
TGADIAFRTYGLELSHKHRPEMQQHAGLEHGVLFAPSVVPAFRGMVVEVPLHLGAMATGPHSDALREALQSFYQGSPVVT
VASGVAPGELLLHRQEQPSDTLTLHVCGNEGGWNVRLVAVLDNLGKGASGAAVQNLNLMAGLDETAGLRLT
>Mature_310_residues
ARSVFIDGAAGTTGLEIRQRLADRTEFDLLVLDDADRKDAAKRREALNDSDFAILCLPDDAAVEAVAMIDPASKTRVIDA
SSAHRVADGWTYGFPEIAGREAVATARFVSNPGCYPTGFIGLVAPLVRTGLLPHDWPFTCNAVSGYSGGGKALIERFEGT
GADIAFRTYGLELSHKHRPEMQQHAGLEHGVLFAPSVVPAFRGMVVEVPLHLGAMATGPHSDALREALQSFYQGSPVVTV
ASGVAPGELLLHRQEQPSDTLTLHVCGNEGGWNVRLVAVLDNLGKGASGAAVQNLNLMAGLDETAGLRLT

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=250, Percent_Identity=29.6, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320913, Length=295, Percent_Identity=29.8305084745763, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR010136
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 32964; Mature: 32832

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSVFIDGAAGTTGLEIRQRLADRTEFDLLVLDDADRKDAAKRREALNDSDFAILCLPD
CCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECC
DAAVEAVAMIDPASKTRVIDASSAHRVADGWTYGFPEIAGREAVATARFVSNPGCYPTGF
HHHHEEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCH
IGLVAPLVRTGLLPHDWPFTCNAVSGYSGGGKALIERFEGTGADIAFRTYGLELSHKHRP
HHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCEEEEEECCEECCCCCC
EMQQHAGLEHGVLFAPSVVPAFRGMVVEVPLHLGAMATGPHSDALREALQSFYQGSPVVT
CHHHHCCCCCCEEECCHHHHHHCCEEEEECHHCCCCCCCCCHHHHHHHHHHHHCCCCEEE
VASGVAPGELLLHRQEQPSDTLTLHVCGNEGGWNVRLVAVLDNLGKGASGAAVQNLNLMA
EECCCCCHHHHEECCCCCCCEEEEEEECCCCCCEEEEEEEEHHCCCCCCCCEEECCEEEE
GLDETAGLRLT
CCCCCCCCCCC
>Mature Secondary Structure 
ARSVFIDGAAGTTGLEIRQRLADRTEFDLLVLDDADRKDAAKRREALNDSDFAILCLPD
CCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECC
DAAVEAVAMIDPASKTRVIDASSAHRVADGWTYGFPEIAGREAVATARFVSNPGCYPTGF
HHHHEEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCH
IGLVAPLVRTGLLPHDWPFTCNAVSGYSGGGKALIERFEGTGADIAFRTYGLELSHKHRP
HHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCEEEEEECCEECCCCCC
EMQQHAGLEHGVLFAPSVVPAFRGMVVEVPLHLGAMATGPHSDALREALQSFYQGSPVVT
CHHHHCCCCCCEEECCHHHHHHCCEEEEECHHCCCCCCCCCHHHHHHHHHHHHCCCCEEE
VASGVAPGELLLHRQEQPSDTLTLHVCGNEGGWNVRLVAVLDNLGKGASGAAVQNLNLMA
EECCCCCHHHHEECCCCCCCEEEEEEECCCCCCEEEEEEEEHHCCCCCCCCEEECCEEEE
GLDETAGLRLT
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406250; 7929012; 11759840 [H]