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The map label for this gene is nadA [H]

Identifier: 85372915

GI number: 85372915

Start: 113884

End: 114912

Strand: Reverse

Name: nadA [H]

Synonym: ELI_00440

Alternate gene names: 85372915

Gene position: 114912-113884 (Counterclockwise)

Preceding gene: 85372917

Following gene: 85372914

Centisome position: 3.76

GC content: 60.25

Gene sequence:

>1029_bases
ATGACCGCTGAAACCAAGCTGCCCACCGGCACAGACCTGATCGCCGAGATCGATCGCCTGCGCAAAGAGCGCAATGCCGT
GATCCTCGCGCATTATTACCAGACGCCCGATATTCAGGACCTGGCCGATTACGTGGGGGATTCGCTGCAGCTTTCGCAGA
TGGCGGCGGAGACCGATGCCGATGTTATCGCCTTCTGCGGCGTGAAGTTCATGGCCGACACGGCGAAAATCTTGTCGCCG
GAGAAAACCGTGGTGCTGCCCGACATGGACGCGGGCTGCAGCCTCGAGGACTCCTGCCCGCCGGAGAAGTTCAAGGCTTT
CCGCGAGGCGCACCCCGATCACATCGCGCTCACCTACATCAACTGCAGCACGGAAGTGAAAGCGCTCTCTGACGTCATCG
TCACCAGCTCCAGCGCAGAGACGATCCTGCAGCAGATCCCGAAGGACCAGAAGATCATCTTCGGGCCGGACCGGCACCTC
GGCGGCTACCTCTCCCGCAAGTTCGACCGCGAAATGCTGCTGTGGCCGGGCGTTTGCATCGTGCATGAAGCCTTCAGCGA
AACCGAACTTCTCAAGCTCAAGCAGCAGCACCCCGACGCGCCGATTGCCGCACACCCGGAATGCCCGCCGACGATTATCG
ACCACGCCGATTACGTCGGCTCGACCAGCGGCATCCTCAAATTCGCCAAGGAATTCGAAGGCGACACGCTGATCGTCGCG
ACCGAGCCGCATATTATCCACCAGATGGAAAAGGCGCTGCCGGAGAAAAACTTTATCGGCGCACCGGGCGCGGACGGAAA
TTGCAGCTGCAATATCTGCCCCTATATGGCGCTCAACACGCTGGAGAAGCTCTACGTGGCGCTGCGCGATCTCGAACCGC
GGATCGAGATCGAGGAAGAACTGCGCCTGAAAGCGAAGAAGAGCCTGGATCGCATGCTGGAAATGGCCAGCGATTCCGTC
GGCAAAGGCGATATCGGCGAAGTCGAGATCGAGGATATCCCCGAAGAGGACATCCCGAGCGGCGACTGA

Upstream 100 bases:

>100_bases
CCCCGGCGGGATAGCAAAGCTTTGTCCAAAATGCTCGCAAAAGCGGCGCAAATCCCTATATCGACCGCAGATTGAGAGCT
GCGACAAGGGGCCGCCCACC

Downstream 100 bases:

>100_bases
GGGTACAGGGTTCTCTGGCTAGCCGCTCGCCCGGTGAGCGCCAGACGGATTAAGGTGAATCGTGCCATCTGTCTGCACCA
TCCCGGTGATATCGAATTGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTAETKLPTGTDLIAEIDRLRKERNAVILAHYYQTPDIQDLADYVGDSLQLSQMAAETDADVIAFCGVKFMADTAKILSP
EKTVVLPDMDAGCSLEDSCPPEKFKAFREAHPDHIALTYINCSTEVKALSDVIVTSSSAETILQQIPKDQKIIFGPDRHL
GGYLSRKFDREMLLWPGVCIVHEAFSETELLKLKQQHPDAPIAAHPECPPTIIDHADYVGSTSGILKFAKEFEGDTLIVA
TEPHIIHQMEKALPEKNFIGAPGADGNCSCNICPYMALNTLEKLYVALRDLEPRIEIEEELRLKAKKSLDRMLEMASDSV
GKGDIGEVEIEDIPEEDIPSGD

Sequences:

>Translated_342_residues
MTAETKLPTGTDLIAEIDRLRKERNAVILAHYYQTPDIQDLADYVGDSLQLSQMAAETDADVIAFCGVKFMADTAKILSP
EKTVVLPDMDAGCSLEDSCPPEKFKAFREAHPDHIALTYINCSTEVKALSDVIVTSSSAETILQQIPKDQKIIFGPDRHL
GGYLSRKFDREMLLWPGVCIVHEAFSETELLKLKQQHPDAPIAAHPECPPTIIDHADYVGSTSGILKFAKEFEGDTLIVA
TEPHIIHQMEKALPEKNFIGAPGADGNCSCNICPYMALNTLEKLYVALRDLEPRIEIEEELRLKAKKSLDRMLEMASDSV
GKGDIGEVEIEDIPEEDIPSGD
>Mature_341_residues
TAETKLPTGTDLIAEIDRLRKERNAVILAHYYQTPDIQDLADYVGDSLQLSQMAAETDADVIAFCGVKFMADTAKILSPE
KTVVLPDMDAGCSLEDSCPPEKFKAFREAHPDHIALTYINCSTEVKALSDVIVTSSSAETILQQIPKDQKIIFGPDRHLG
GYLSRKFDREMLLWPGVCIVHEAFSETELLKLKQQHPDAPIAAHPECPPTIIDHADYVGSTSGILKFAKEFEGDTLIVAT
EPHIIHQMEKALPEKNFIGAPGADGNCSCNICPYMALNTLEKLYVALRDLEPRIEIEEELRLKAKKSLDRMLEMASDSVG
KGDIGEVEIEDIPEEDIPSGD

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=316, Percent_Identity=43.3544303797468, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37765; Mature: 37634

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAETKLPTGTDLIAEIDRLRKERNAVILAHYYQTPDIQDLADYVGDSLQLSQMAAETDA
CCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHCCC
DVIAFCGVKFMADTAKILSPEKTVVLPDMDAGCSLEDSCPPEKFKAFREAHPDHIALTYI
CCHHHHCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
NCSTEVKALSDVIVTSSSAETILQQIPKDQKIIFGPDRHLGGYLSRKFDREMLLWPGVCI
ECCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCHHHCCCHHH
VHEAFSETELLKLKQQHPDAPIAAHPECPPTIIDHADYVGSTSGILKFAKEFEGDTLIVA
HHHHHCHHHHHHHHHHCCCCCCCCCCCCCCHHHCCHHHCCCHHHHHHHHHHCCCCEEEEE
TEPHIIHQMEKALPEKNFIGAPGADGNCSCNICPYMALNTLEKLYVALRDLEPRIEIEEE
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
LRLKAKKSLDRMLEMASDSVGKGDIGEVEIEDIPEEDIPSGD
HHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCC
>Mature Secondary Structure 
TAETKLPTGTDLIAEIDRLRKERNAVILAHYYQTPDIQDLADYVGDSLQLSQMAAETDA
CCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHCCC
DVIAFCGVKFMADTAKILSPEKTVVLPDMDAGCSLEDSCPPEKFKAFREAHPDHIALTYI
CCHHHHCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
NCSTEVKALSDVIVTSSSAETILQQIPKDQKIIFGPDRHLGGYLSRKFDREMLLWPGVCI
ECCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCHHHCCCHHH
VHEAFSETELLKLKQQHPDAPIAAHPECPPTIIDHADYVGSTSGILKFAKEFEGDTLIVA
HHHHHCHHHHHHHHHHCCCCCCCCCCCCCCHHHCCHHHCCCHHHHHHHHHHCCCCEEEEE
TEPHIIHQMEKALPEKNFIGAPGADGNCSCNICPYMALNTLEKLYVALRDLEPRIEIEEE
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
LRLKAKKSLDRMLEMASDSVGKGDIGEVEIEDIPEEDIPSGD
HHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA