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The map label for this gene is exuT [H]

Identifier: 85372894

GI number: 85372894

Start: 92814

End: 94118

Strand: Direct

Name: exuT [H]

Synonym: ELI_00335

Alternate gene names: 85372894

Gene position: 92814-94118 (Clockwise)

Preceding gene: 85372893

Following gene: 85372898

Centisome position: 3.04

GC content: 64.29

Gene sequence:

>1305_bases
ATGGCGACAGCGACAGGCATTGCGGGGGGGGCGCCTGCGGGCGAGGTGAGCGACCGTGCGCGCAAGGTCACGCTGTTTCT
CCTCACCGTCACCTATTTCTTCAGCTACATGGACCGGCAGATCCTTGCGATCCTGCTGGAGGACATCAAGGCCGACCTGC
TTTTGTCCGACACGCAGCTGGGTCTGCTGTCCGGCTTCGCCTTCGCGCTGTTCTACGCCACGCTCGGCATCCCGGTCGCA
GCGCTGGCCGACCGGATGAACCGGATCAACATCATCTCGATCGCGCTCGCGCTGTGGAGCGCGATGACCGCTGCCTGCGG
GCTGGCGCAGAATTTCATCCAGCTGCTGGCCGCGCGCGTCGGGGTCGGAATCGGGGAGGCCGGCTCCAGCCCGCCGAGCC
ATTCGATCATTGCCGACCTCTATCCGGCGGAAAAGCGTGCGCTCGCACTGTCGATCTACTCGCTCGGCGTGACGCTGGGC
GCTGCGGCGGGGCAGATGTTCGGAGGAAATCTTACCTATTTCTTCGATTGGCGCGTGGCGTTTATCGTCATCGGCCTCCC
GGGGGTCATGCTGGCAATTTTCGTCAAGCTGTTCGCGACCGAGCCGCCGCGCCGGGCCGAGCCGGGCGCAGTCGACAGCG
AAGACCAGCCGAGCATCGGGGAGGGCTTCACCACAATCCTCTCGAACCGCTCGGCCCGCTGGATGATCGCGGGCGTCACA
CTGACGTCGATGATCGGTTACGCGCTGACCGGCTGGACCCCGGCCTACCTGATCCGGATTTTCGACCTCAACACGCTTCA
GGTCGGGAATATCGTCGCGCCGCTGCTTGCTATAGCCGGTGTCGCGAGCGGGCTGGGTGGCGGCTGGCTCGCAAACCGGA
TGACCGCTCGCGACGGATTGTGGCGGCAGCCCTGGATGATCGCGATACTCAAGACCATCGCCCTGCCATTCCTGATATGG
TTCTATCTCGCGGGCGATGCATGGATGGCGGTCGGCGTCTATTTCGTCGCCGTGCTCTTCCAGTCGAGCTACCTCGGTCC
GACCTTCGCGGTGATCCAGACGCTCGCCCCGCTCAAGATGCGCGCTGTGTGGGCGGCCATCACGCTGTTGATCATCAACC
TGATCGGGCTGGGGCTGGGGCCGACCATGGTCGGGGTGCTGTCTGACCTGTTCGCGCCGCGCTTCGGAAATGAGTCATTG
CGCTACGCCCTGCTGGTGGTGGCGGCGGCAACACCGGTCGCGATCCTCTGTTACTGGCGCGCTGCGGTATTGATGAAGCA
TGACTATCCCAAGGCTGCGGTTTGA

Upstream 100 bases:

>100_bases
GCTTCGGCATCCGGACGCGGTTCTGATCGGCTGAACAGGCAGGGGGCCGGGGACCAGTTCTCCGGCCCCCTTGCTTTGCG
AGCAAGCGGGGAGAGCAGAC

Downstream 100 bases:

>100_bases
ACCGAAATCAGCCCATCGGCTCCATGGCTTGCTGTTCCAAGGCGTTCTGCACGCCCTTGTCCTGTTCCATCCGGTTGCGA
AATTCGGCGAGCTGCGGATA

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MATATGIAGGAPAGEVSDRARKVTLFLLTVTYFFSYMDRQILAILLEDIKADLLLSDTQLGLLSGFAFALFYATLGIPVA
ALADRMNRINIISIALALWSAMTAACGLAQNFIQLLAARVGVGIGEAGSSPPSHSIIADLYPAEKRALALSIYSLGVTLG
AAAGQMFGGNLTYFFDWRVAFIVIGLPGVMLAIFVKLFATEPPRRAEPGAVDSEDQPSIGEGFTTILSNRSARWMIAGVT
LTSMIGYALTGWTPAYLIRIFDLNTLQVGNIVAPLLAIAGVASGLGGGWLANRMTARDGLWRQPWMIAILKTIALPFLIW
FYLAGDAWMAVGVYFVAVLFQSSYLGPTFAVIQTLAPLKMRAVWAAITLLIINLIGLGLGPTMVGVLSDLFAPRFGNESL
RYALLVVAAATPVAILCYWRAAVLMKHDYPKAAV

Sequences:

>Translated_434_residues
MATATGIAGGAPAGEVSDRARKVTLFLLTVTYFFSYMDRQILAILLEDIKADLLLSDTQLGLLSGFAFALFYATLGIPVA
ALADRMNRINIISIALALWSAMTAACGLAQNFIQLLAARVGVGIGEAGSSPPSHSIIADLYPAEKRALALSIYSLGVTLG
AAAGQMFGGNLTYFFDWRVAFIVIGLPGVMLAIFVKLFATEPPRRAEPGAVDSEDQPSIGEGFTTILSNRSARWMIAGVT
LTSMIGYALTGWTPAYLIRIFDLNTLQVGNIVAPLLAIAGVASGLGGGWLANRMTARDGLWRQPWMIAILKTIALPFLIW
FYLAGDAWMAVGVYFVAVLFQSSYLGPTFAVIQTLAPLKMRAVWAAITLLIINLIGLGLGPTMVGVLSDLFAPRFGNESL
RYALLVVAAATPVAILCYWRAAVLMKHDYPKAAV
>Mature_433_residues
ATATGIAGGAPAGEVSDRARKVTLFLLTVTYFFSYMDRQILAILLEDIKADLLLSDTQLGLLSGFAFALFYATLGIPVAA
LADRMNRINIISIALALWSAMTAACGLAQNFIQLLAARVGVGIGEAGSSPPSHSIIADLYPAEKRALALSIYSLGVTLGA
AAGQMFGGNLTYFFDWRVAFIVIGLPGVMLAIFVKLFATEPPRRAEPGAVDSEDQPSIGEGFTTILSNRSARWMIAGVTL
TSMIGYALTGWTPAYLIRIFDLNTLQVGNIVAPLLAIAGVASGLGGGWLANRMTARDGLWRQPWMIAILKTIALPFLIWF
YLAGDAWMAVGVYFVAVLFQSSYLGPTFAVIQTLAPLKMRAVWAAITLLIINLIGLGLGPTMVGVLSDLFAPRFGNESLR
YALLVVAAATPVAILCYWRAAVLMKHDYPKAAV

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=262, Percent_Identity=28.2442748091603, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI215490096, Length=242, Percent_Identity=29.7520661157025, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI14042968, Length=242, Percent_Identity=29.7520661157025, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI215490100, Length=232, Percent_Identity=30.1724137931034, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI215490102, Length=193, Percent_Identity=31.0880829015544, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI194239645, Length=256, Percent_Identity=26.5625, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI2367379, Length=286, Percent_Identity=26.5734265734266, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1789515, Length=306, Percent_Identity=26.797385620915, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789152, Length=443, Percent_Identity=24.6049661399549, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87082320, Length=302, Percent_Identity=25.4966887417219, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193209775, Length=455, Percent_Identity=22.8571428571429, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17539092, Length=435, Percent_Identity=24.1379310344828, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17557872, Length=411, Percent_Identity=24.5742092457421, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71992409, Length=408, Percent_Identity=22.5490196078431, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24654044, Length=240, Percent_Identity=27.9166666666667, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24654037, Length=382, Percent_Identity=24.6073298429319, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24654041, Length=382, Percent_Identity=24.6073298429319, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24654039, Length=240, Percent_Identity=27.9166666666667, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17864456, Length=240, Percent_Identity=27.9166666666667, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640209, Length=348, Percent_Identity=23.8505747126437, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46350; Mature: 46219

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATATGIAGGAPAGEVSDRARKVTLFLLTVTYFFSYMDRQILAILLEDIKADLLLSDTQL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHH
GLLSGFAFALFYATLGIPVAALADRMNRINIISIALALWSAMTAACGLAQNFIQLLAARV
HHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGIGEAGSSPPSHSIIADLYPAEKRALALSIYSLGVTLGAAAGQMFGGNLTYFFDWRVA
CCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
FIVIGLPGVMLAIFVKLFATEPPRRAEPGAVDSEDQPSIGEGFTTILSNRSARWMIAGVT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEHHH
LTSMIGYALTGWTPAYLIRIFDLNTLQVGNIVAPLLAIAGVASGLGGGWLANRMTARDGL
HHHHHHHHHCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
WRQPWMIAILKTIALPFLIWFYLAGDAWMAVGVYFVAVLFQSSYLGPTFAVIQTLAPLKM
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RAVWAAITLLIINLIGLGLGPTMVGVLSDLFAPRFGNESLRYALLVVAAATPVAILCYWR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAVLMKHDYPKAAV
HHHHHHCCCCCCCC
>Mature Secondary Structure 
ATATGIAGGAPAGEVSDRARKVTLFLLTVTYFFSYMDRQILAILLEDIKADLLLSDTQL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHH
GLLSGFAFALFYATLGIPVAALADRMNRINIISIALALWSAMTAACGLAQNFIQLLAARV
HHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGIGEAGSSPPSHSIIADLYPAEKRALALSIYSLGVTLGAAAGQMFGGNLTYFFDWRVA
CCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
FIVIGLPGVMLAIFVKLFATEPPRRAEPGAVDSEDQPSIGEGFTTILSNRSARWMIAGVT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEHHH
LTSMIGYALTGWTPAYLIRIFDLNTLQVGNIVAPLLAIAGVASGLGGGWLANRMTARDGL
HHHHHHHHHCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
WRQPWMIAILKTIALPFLIWFYLAGDAWMAVGVYFVAVLFQSSYLGPTFAVIQTLAPLKM
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RAVWAAITLLIINLIGLGLGPTMVGVLSDLFAPRFGNESLRYALLVVAAATPVAILCYWR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAVLMKHDYPKAAV
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]