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The map label for this gene is ribD [H]

Identifier: 85372857

GI number: 85372857

Start: 42359

End: 43336

Strand: Reverse

Name: ribD [H]

Synonym: ELI_00150

Alternate gene names: 85372857

Gene position: 43336-42359 (Counterclockwise)

Preceding gene: 85372858

Following gene: 85372856

Centisome position: 1.42

GC content: 67.28

Gene sequence:

>978_bases
GTGATCGGGCCGCGGGGGGATCAGGACTGGCTCGCCGCCGCCGCACGCCTTGCCAGTCGTGGCCGCCCCGTGAGTGCACC
CAACCCCGCTGTCGGTTGCATCATCGTCAAGCAGGATCGCGTGATCGGTCGCGGCTGGACACGCGTTGGCGGCCGACCAC
ATGCCGAGGCGGCGGCACTCGAACAGGCCGGCCAAGACGCGCGAGGGGCGACGATCTATGTCACGCTCGAGCCCTGCGCC
CATGAATCCGATCGCGGCCCCTCCTGTGCGGACTTGCTGGTTGCTGCGCGACCGCAGAGGGTCGTGCTGGCGGAGGTCGA
TCCAGACCGGCGAACACATGGTGCCGGGATCGCGCGCCTGCGCAGAAGCGGCATCACGGTCGAAACGCTGCCGTCCCCTG
CAGCTGCGGCCAGCCTTGCAGGCTTTCTCACCCGCGAACGTCTCGGGCGGCCGCATGTCACGCTCAAGCTCGCTCTCTCG
CTCGATGGCTGCATCGCTCTCGCGAGCGGCGAAAGCCAGTGGATCACAGGCGAAGAAGCGCGCGCGCATTGTCACTCGCG
CCGTGCGATGAGCGATGCCATCCTGGTCGGCGGCGGTACCTGGCGTGCCGACAAACCGCGTCTCGACGTGCGCTTGCCGG
GGCTCGAAGACCGCAGCCCGCAGCGCGTCGTCCTCACCCGTGGCGTACCCATCGACGGCGTGCGGATCATCAACGAACCG
GCCCAGATCGACCGGCTCGAGGCTGCGCAATATCTCTATGTCGAAGGCGGCGCGGGCGCGGCTGCCAGTTTTCTTGCCGA
AAACCTGGTCGACCGGCTCGACATCTATCGTGCCCCGATCGTGATCGGGGGCGGCAAACCGGCCTTCGGCAATATCGGAC
TAGCCGACCTCACGTCCGCCCACGGAAGCTGGAAACTGGTCGAACGCCGCCAGCTTGGCAGCGATTGCTACGAAGCCTAT
GAGCGGCAACGAAGCTAA

Upstream 100 bases:

>100_bases
TGGAGGCCGAAGCCGAAGCCGAGCGCATCCGCGAAGAGGCCGAGGCGGAAATCGAAAGGCGCGAGCGGCTCGATGCCGCG
GGGCTGGAAGAGATCGAATA

Downstream 100 bases:

>100_bases
GGAGCACGCATGTTTACCGGTATCGTCACCGCCATCGGCACCATCGAAAGCGCAGAGCAACTAAGCGACCTGCGCGTGCG
CGTGCGCTGCCCTTACGACC

Product: riboflavin-specific deaminase/reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MIGPRGDQDWLAAAARLASRGRPVSAPNPAVGCIIVKQDRVIGRGWTRVGGRPHAEAAALEQAGQDARGATIYVTLEPCA
HESDRGPSCADLLVAARPQRVVLAEVDPDRRTHGAGIARLRRSGITVETLPSPAAAASLAGFLTRERLGRPHVTLKLALS
LDGCIALASGESQWITGEEARAHCHSRRAMSDAILVGGGTWRADKPRLDVRLPGLEDRSPQRVVLTRGVPIDGVRIINEP
AQIDRLEAAQYLYVEGGAGAAASFLAENLVDRLDIYRAPIVIGGGKPAFGNIGLADLTSAHGSWKLVERRQLGSDCYEAY
ERQRS

Sequences:

>Translated_325_residues
MIGPRGDQDWLAAAARLASRGRPVSAPNPAVGCIIVKQDRVIGRGWTRVGGRPHAEAAALEQAGQDARGATIYVTLEPCA
HESDRGPSCADLLVAARPQRVVLAEVDPDRRTHGAGIARLRRSGITVETLPSPAAAASLAGFLTRERLGRPHVTLKLALS
LDGCIALASGESQWITGEEARAHCHSRRAMSDAILVGGGTWRADKPRLDVRLPGLEDRSPQRVVLTRGVPIDGVRIINEP
AQIDRLEAAQYLYVEGGAGAAASFLAENLVDRLDIYRAPIVIGGGKPAFGNIGLADLTSAHGSWKLVERRQLGSDCYEAY
ERQRS
>Mature_325_residues
MIGPRGDQDWLAAAARLASRGRPVSAPNPAVGCIIVKQDRVIGRGWTRVGGRPHAEAAALEQAGQDARGATIYVTLEPCA
HESDRGPSCADLLVAARPQRVVLAEVDPDRRTHGAGIARLRRSGITVETLPSPAAAASLAGFLTRERLGRPHVTLKLALS
LDGCIALASGESQWITGEEARAHCHSRRAMSDAILVGGGTWRADKPRLDVRLPGLEDRSPQRVVLTRGVPIDGVRIINEP
AQIDRLEAAQYLYVEGGAGAAASFLAENLVDRLDIYRAPIVIGGGKPAFGNIGLADLTSAHGSWKLVERRQLGSDCYEAY
ERQRS

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=361, Percent_Identity=36.8421052631579, Blast_Score=188, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 34697; Mature: 34697

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGPRGDQDWLAAAARLASRGRPVSAPNPAVGCIIVKQDRVIGRGWTRVGGRPHAEAAAL
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEECCCHHHCCCCCCHHHHHH
EQAGQDARGATIYVTLEPCAHESDRGPSCADLLVAARPQRVVLAEVDPDRRTHGAGIARL
HHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHH
RRSGITVETLPSPAAAASLAGFLTRERLGRPHVTLKLALSLDGCIALASGESQWITGEEA
HHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEECCCCCEECCHHH
RAHCHSRRAMSDAILVGGGTWRADKPRLDVRLPGLEDRSPQRVVLTRGVPIDGVRIINEP
HHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCEEEECCC
AQIDRLEAAQYLYVEGGAGAAASFLAENLVDRLDIYRAPIVIGGGKPAFGNIGLADLTSA
HHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHCC
HGSWKLVERRQLGSDCYEAYERQRS
CCCEEEHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MIGPRGDQDWLAAAARLASRGRPVSAPNPAVGCIIVKQDRVIGRGWTRVGGRPHAEAAAL
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEECCCHHHCCCCCCHHHHHH
EQAGQDARGATIYVTLEPCAHESDRGPSCADLLVAARPQRVVLAEVDPDRRTHGAGIARL
HHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHH
RRSGITVETLPSPAAAASLAGFLTRERLGRPHVTLKLALSLDGCIALASGESQWITGEEA
HHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEECCCCCEECCHHH
RAHCHSRRAMSDAILVGGGTWRADKPRLDVRLPGLEDRSPQRVVLTRGVPIDGVRIINEP
HHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCEEEECCC
AQIDRLEAAQYLYVEGGAGAAASFLAENLVDRLDIYRAPIVIGGGKPAFGNIGLADLTSA
HHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHCC
HGSWKLVERRQLGSDCYEAYERQRS
CCCEEEHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]