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The map label for this gene is rnpA

Identifier: 85060409

GI number: 85060409

Start: 4169990

End: 4170349

Strand: Reverse

Name: rnpA

Synonym: SG2431

Alternate gene names: 85060409

Gene position: 4170349-4169990 (Counterclockwise)

Preceding gene: 85060410

Following gene: 85060408

Centisome position: 99.98

GC content: 55.28

Gene sequence:

>360_bases
GTGGTTAAGCTCGCATTTCCCCGGGAGTTACGGTTGTTAACTCCCAATCACTTTACTTTTGTCTTCCAGCAGCCTCAATG
GGCCGGCACGCCGCATGTTACCATCCTCGGCCGCCTGAACACGCTGGGGCATCCCCGCGTCGGTCTCACGGTCGCCAAAA
AACATGTAAAACGGGCCCATGAACGTAACCGGATCAAGCGCTTGACGCGCGAAAGTTTCCGCCTGCATCAGCATGCCCTG
CCCACCATGGATTTTGTGGTCATCGCCAAAAAAGGCGTGGCCGATCTGGATAACCATACCCTGACGGAAGCGTTAGAAAA
ATTATGGCGCCGCCATTGTCGCCAGTCTCAAAGCTGCTGA

Upstream 100 bases:

>100_bases
GTATGGCAACGAAGAACGGTCGTCAGGTTTTGGCACGTCGTCGTGCAAAAGGCCGTACACGCCTGACCTTATCTTCCAAG
TAAGAAAGCTTGCCCACCGG

Downstream 100 bases:

>100_bases
TCGGGTTGATACGCGGTTATCAACTCGTCATCAGCCCGTTGCTGGGGCCTCATTGCCGGTTCCGGCCCACTTGTTCGCAG
TATGGAATTGAGGCAATACG

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MVKLAFPRELRLLTPNHFTFVFQQPQWAGTPHVTILGRLNTLGHPRVGLTVAKKHVKRAHERNRIKRLTRESFRLHQHAL
PTMDFVVIAKKGVADLDNHTLTEALEKLWRRHCRQSQSC

Sequences:

>Translated_119_residues
MVKLAFPRELRLLTPNHFTFVFQQPQWAGTPHVTILGRLNTLGHPRVGLTVAKKHVKRAHERNRIKRLTRESFRLHQHAL
PTMDFVVIAKKGVADLDNHTLTEALEKLWRRHCRQSQSC
>Mature_119_residues
MVKLAFPRELRLLTPNHFTFVFQQPQWAGTPHVTILGRLNTLGHPRVGLTVAKKHVKRAHERNRIKRLTRESFRLHQHAL
PTMDFVVIAKKGVADLDNHTLTEALEKLWRRHCRQSQSC

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

Organism=Escherichia coli, GI1790139, Length=114, Percent_Identity=85.9649122807018, Blast_Score=208, Evalue=8e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_SODGM (Q2NQ69)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_456111.1
- ProteinModelPortal:   Q2NQ69
- SMR:   Q2NQ69
- STRING:   Q2NQ69
- GeneID:   3866327
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG2431
- NMPDR:   fig|343509.6.peg.5249
- eggNOG:   COG0594
- HOGENOM:   HBG728160
- OMA:   LVIGKKS
- PhylomeDB:   Q2NQ69
- ProtClustDB:   PRK01732
- BioCyc:   SGLO343509:SG2431-MONOMER
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13886; Mature: 13886

Theoretical pI: Translated: 11.90; Mature: 11.90

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLAFPRELRLLTPNHFTFVFQQPQWAGTPHVTILGRLNTLGHPRVGLTVAKKHVKRAH
CCCCCCCCCEEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
ERNRIKRLTRESFRLHQHALPTMDFVVIAKKGVADLDNHTLTEALEKLWRRHCRQSQSC
HHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVKLAFPRELRLLTPNHFTFVFQQPQWAGTPHVTILGRLNTLGHPRVGLTVAKKHVKRAH
CCCCCCCCCEEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
ERNRIKRLTRESFRLHQHALPTMDFVVIAKKGVADLDNHTLTEALEKLWRRHCRQSQSC
HHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA