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The map label for this gene is wecF [H]

Identifier: 85060354

GI number: 85060354

Start: 4080277

End: 4081362

Strand: Reverse

Name: wecF [H]

Synonym: SG2376

Alternate gene names: 85060354

Gene position: 4081362-4080277 (Counterclockwise)

Preceding gene: 85060355

Following gene: 85060353

Centisome position: 97.85

GC content: 61.23

Gene sequence:

>1086_bases
ATGAGTAATTTGATCCATGTGCTGGGTTCCGATATCCCGCATCATAATGTGACGGTGTTGCGTTTCTTTAACGATACGCT
GGCGGCAATTTGCCCGCCGGCGCAGACCCGGCGTTTTATGGTGGTTGCCCGGGACAACGCGCCTTTTTCCCATTGCGGCC
AGCTGGATATTGAACGGTTCGACAGCAAACGGGCATTGACCAAAGCGCTGATCCGCGGCGCCGCCGCGGCGCCGGACGAA
CGCTATTTTCTGCACGGCCAATTCAATCCCTCGCTCTGGCTGGCGATGCTGACGGGCAAAATACGCCCGGCGCGCCTGAG
TTGGCACGTATGGGGCGCGGATCTGTATGAAGATTCACGCCGTCTGCGCCACCGGTGGTTCTATCTGCTGCGCCGCCGTG
CTCAGGGACGGGTTGGCCATGTGCTCGCGACCCGGGGCGACCTGGCCTGTTACCGCCAGCGTCATCCGTCGGTACCGGCT
TCGCTGCTCTATTTTCCCACCCGTCTGGCCACGGATATCGCGCGGGCGACGCCTGATAAGGCAGACAATCGGCCGCTGAC
GCTGCTGGTGGGGAATTCCGGTGATGCGTCTAACCGCCACAGTCAGGCACTGCGCGCCATTCATCATCACTTTGGTACCG
GAGTAAGCATAATTGTGCCGATGGGCTATCCCGCCGGCAACGATGCCTATATTGCCACGGTGCGGGCGCAGGCAGAGCGC
TGCTTCCCGGCTGGGCAGGTACAGATTCTCACCGAACAGTTGGCCTTTGACGATTATCTCGCGCTACTGCGGCAGTGCGA
TGCCGGCTATTTTCTGTTTCCACGCCAGCAGGGTATCGGCACGCTGAGCCTGTTGATCCAGCTTGGCCTGCCTTTCGTGC
TCAGCCGGCACAATCCGTTCTGCCAGGATCTTCAGGCGCAGCAGGTGCCGGTGCTGTATGAGGATGACGCGCTCGACGCC
GCCATGATCCGCGAGGCGCAGCGGCGCATGCTAGCGCTGGATCCGGCGCGCATCGACTTTTTTTACCCCAATATCCTGCA
AGGCTGGCGCCAGGCGCTCTCCATCGCCGCGGGAGTACCGCTATGA

Upstream 100 bases:

>100_bases
CGCGTCACGGCGCGCTGGGCGCGACCCAGGCCTATATGGCCACCTATATCGTCTATTTCGCGCTGTGCGGCGGTTTGTTC
TTACTCTATCTTAGGAAAAA

Downstream 100 bases:

>100_bases
CCCTTGCGCAGTTCGGCGGCCTGCTGGTGGTCTATATATTATCGCTCACGTTGGTGGCGGCGCTGACCTACCGGGAGTTT
CGGTGGGTCAGGTTTAATTT

Product: 4-alpha-L-fucosyltransferase

Products: NA

Alternate protein names: TDP-Fuc4NAc:lipid II Fuc4NAc transferase; Fuc4NAc transferase [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSNLIHVLGSDIPHHNVTVLRFFNDTLAAICPPAQTRRFMVVARDNAPFSHCGQLDIERFDSKRALTKALIRGAAAAPDE
RYFLHGQFNPSLWLAMLTGKIRPARLSWHVWGADLYEDSRRLRHRWFYLLRRRAQGRVGHVLATRGDLACYRQRHPSVPA
SLLYFPTRLATDIARATPDKADNRPLTLLVGNSGDASNRHSQALRAIHHHFGTGVSIIVPMGYPAGNDAYIATVRAQAER
CFPAGQVQILTEQLAFDDYLALLRQCDAGYFLFPRQQGIGTLSLLIQLGLPFVLSRHNPFCQDLQAQQVPVLYEDDALDA
AMIREAQRRMLALDPARIDFFYPNILQGWRQALSIAAGVPL

Sequences:

>Translated_361_residues
MSNLIHVLGSDIPHHNVTVLRFFNDTLAAICPPAQTRRFMVVARDNAPFSHCGQLDIERFDSKRALTKALIRGAAAAPDE
RYFLHGQFNPSLWLAMLTGKIRPARLSWHVWGADLYEDSRRLRHRWFYLLRRRAQGRVGHVLATRGDLACYRQRHPSVPA
SLLYFPTRLATDIARATPDKADNRPLTLLVGNSGDASNRHSQALRAIHHHFGTGVSIIVPMGYPAGNDAYIATVRAQAER
CFPAGQVQILTEQLAFDDYLALLRQCDAGYFLFPRQQGIGTLSLLIQLGLPFVLSRHNPFCQDLQAQQVPVLYEDDALDA
AMIREAQRRMLALDPARIDFFYPNILQGWRQALSIAAGVPL
>Mature_360_residues
SNLIHVLGSDIPHHNVTVLRFFNDTLAAICPPAQTRRFMVVARDNAPFSHCGQLDIERFDSKRALTKALIRGAAAAPDER
YFLHGQFNPSLWLAMLTGKIRPARLSWHVWGADLYEDSRRLRHRWFYLLRRRAQGRVGHVLATRGDLACYRQRHPSVPAS
LLYFPTRLATDIARATPDKADNRPLTLLVGNSGDASNRHSQALRAIHHHFGTGVSIIVPMGYPAGNDAYIATVRAQAERC
FPAGQVQILTEQLAFDDYLALLRQCDAGYFLFPRQQGIGTLSLLIQLGLPFVLSRHNPFCQDLQAQQVPVLYEDDALDAA
MIREAQRRMLALDPARIDFFYPNILQGWRQALSIAAGVPL

Specific function: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 56 family [H]

Homologues:

Organism=Escherichia coli, GI48994971, Length=357, Percent_Identity=54.9019607843137, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009993 [H]

Pfam domain/function: PF07429 Fuc4NAc_transf [H]

EC number: NA

Molecular weight: Translated: 40593; Mature: 40462

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLIHVLGSDIPHHNVTVLRFFNDTLAAICPPAQTRRFMVVARDNAPFSHCGQLDIERF
CCCHHHHHCCCCCCCCEEEEEEECCHHHHHCCCCCCCEEEEEEECCCCHHHCCCCCHHHH
DSKRALTKALIRGAAAAPDERYFLHGQFNPSLWLAMLTGKIRPARLSWHVWGADLYEDSR
HHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHEEEEHHCCCCCCEEEEEEECCHHHHHHH
RLRHRWFYLLRRRAQGRVGHVLATRGDLACYRQRHPSVPASLLYFPTRLATDIARATPDK
HHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
ADNRPLTLLVGNSGDASNRHSQALRAIHHHFGTGVSIIVPMGYPAGNDAYIATVRAQAER
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEHHHHH
CFPAGQVQILTEQLAFDDYLALLRQCDAGYFLFPRQQGIGTLSLLIQLGLPFVLSRHNPF
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCEECCCCCH
CQDLQAQQVPVLYEDDALDAAMIREAQRRMLALDPARIDFFYPNILQGWRQALSIAAGVP
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHEECCCHHEEEECHHHHHHHHHHHHHHCCCC
L
C
>Mature Secondary Structure 
SNLIHVLGSDIPHHNVTVLRFFNDTLAAICPPAQTRRFMVVARDNAPFSHCGQLDIERF
CCHHHHHCCCCCCCCEEEEEEECCHHHHHCCCCCCCEEEEEEECCCCHHHCCCCCHHHH
DSKRALTKALIRGAAAAPDERYFLHGQFNPSLWLAMLTGKIRPARLSWHVWGADLYEDSR
HHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHEEEEHHCCCCCCEEEEEEECCHHHHHHH
RLRHRWFYLLRRRAQGRVGHVLATRGDLACYRQRHPSVPASLLYFPTRLATDIARATPDK
HHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
ADNRPLTLLVGNSGDASNRHSQALRAIHHHFGTGVSIIVPMGYPAGNDAYIATVRAQAER
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEHHHHH
CFPAGQVQILTEQLAFDDYLALLRQCDAGYFLFPRQQGIGTLSLLIQLGLPFVLSRHNPF
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCEECCCCCH
CQDLQAQQVPVLYEDDALDAAMIREAQRRMLALDPARIDFFYPNILQGWRQALSIAAGVP
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHEECCCHHEEEECHHHHHHHHHHHHHHCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA