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The map label for this gene is gntR [H]

Identifier: 85060311

GI number: 85060311

Start: 4008727

End: 4009722

Strand: Reverse

Name: gntR [H]

Synonym: SG2333

Alternate gene names: 85060311

Gene position: 4009722-4008727 (Counterclockwise)

Preceding gene: 85060312

Following gene: 85060310

Centisome position: 96.13

GC content: 58.33

Gene sequence:

>996_bases
ATGAAGAAAAAAAGGCCGGGACTGCAGGATGTCGCCGATCAAGTTGGGGTAACCAAAATGACGGTGAGTCGCTATCTGCG
CGATCCGGATCGGGTCTCTCAGGCGCTGCAGGCGAAGATCGCCGCGGCGCTTGATAGCCTGGGTTATATCCCTAACCGGG
CGCCGGATATCCTCTCCAACGCCACCAGCCGCGCTATCGGCGTGTTGCTGCCTTCGCTGACTAATCAGGTTTTCGCCGAA
GTCCTGCGCGGGATTGAGCAGGTCACCGATGCCAACGGCTATCAGACCATGCTGGCGCACTACGGTTATTCGCCGGAGCT
GGAAGAGCTGCGGCTGACCTCGCTACTGTCTTATAACATTGACGGCCTTATCCTGTCCGAACGCCATCATTCCCCCCGTA
CGCTGAAAATGATCGAAGTGGCCGGTATTCCGGTGGTGGAGATCATGGATTGCGTCTCCCCCTGTCTGGATATGGCGGTG
GGGTTTGATAATTTCGAGGCGGCACGGCAAATGACCCGGCTTATCGTCGAGCGTGGGCATCATCAAGTGGTGTATTTCGG
CGCCCGACAGGATGAACGTACCCTAATTAAGCAGCAAGGGTATGAGCAAGGCATGCGCGACGCCGGCCTGCCCGCCTATA
GCGTCATGATGGCGGACTCCTCCAACTATTCCGCCGGCGTGGAATTACTGTGCCAGACGCAGCGGGAGTATCCCGGTATC
AACGGCATAATCAGCACCAATGACGACTTGGCCATAGGCGCATTGTTTGAATGCCAGCGCCAGGGGATTACCGTGCCCGA
CAGGATGGCGATAGCTGGTTTTCACGGTCACGACTTCTCCCGCGTTGCTCATCCACGCTTGGCCAGCGTACTTACTCCCC
GTGAAGAAATGGGGCGCCTGAGCGCCGACTGCCTGTTGGCCCGCCTGCGGGGCGAACCGCGCGCCGACGGGCAAATCGAC
GTCGGTTTTACGTTACTGACCGGGGAAAGTATTTGA

Upstream 100 bases:

>100_bases
CTGTTTGATCTGTCCCCGGTTTGACCGGAATAAAAATACTCGGCAGCGGATTTTTTTGTTAAACTTAGCTGAATCGTCGG
TGGAGGTTAACAAGTTAATA

Downstream 100 bases:

>100_bases
CCCTTACAGCGTAGCAGGCAACTTACCGTCGCAACGTTCATAGGAACAGGGCCGTCCACTTTCTTCCTTCACCCTGCCGA
CCGGGAGAATTCTCTGACCC

Product: gluconate utilization operon repressor

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKKKRPGLQDVADQVGVTKMTVSRYLRDPDRVSQALQAKIAAALDSLGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAE
VLRGIEQVTDANGYQTMLAHYGYSPELEELRLTSLLSYNIDGLILSERHHSPRTLKMIEVAGIPVVEIMDCVSPCLDMAV
GFDNFEAARQMTRLIVERGHHQVVYFGARQDERTLIKQQGYEQGMRDAGLPAYSVMMADSSNYSAGVELLCQTQREYPGI
NGIISTNDDLAIGALFECQRQGITVPDRMAIAGFHGHDFSRVAHPRLASVLTPREEMGRLSADCLLARLRGEPRADGQID
VGFTLLTGESI

Sequences:

>Translated_331_residues
MKKKRPGLQDVADQVGVTKMTVSRYLRDPDRVSQALQAKIAAALDSLGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAE
VLRGIEQVTDANGYQTMLAHYGYSPELEELRLTSLLSYNIDGLILSERHHSPRTLKMIEVAGIPVVEIMDCVSPCLDMAV
GFDNFEAARQMTRLIVERGHHQVVYFGARQDERTLIKQQGYEQGMRDAGLPAYSVMMADSSNYSAGVELLCQTQREYPGI
NGIISTNDDLAIGALFECQRQGITVPDRMAIAGFHGHDFSRVAHPRLASVLTPREEMGRLSADCLLARLRGEPRADGQID
VGFTLLTGESI
>Mature_331_residues
MKKKRPGLQDVADQVGVTKMTVSRYLRDPDRVSQALQAKIAAALDSLGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAE
VLRGIEQVTDANGYQTMLAHYGYSPELEELRLTSLLSYNIDGLILSERHHSPRTLKMIEVAGIPVVEIMDCVSPCLDMAV
GFDNFEAARQMTRLIVERGHHQVVYFGARQDERTLIKQQGYEQGMRDAGLPAYSVMMADSSNYSAGVELLCQTQREYPGI
NGIISTNDDLAIGALFECQRQGITVPDRMAIAGFHGHDFSRVAHPRLASVLTPREEMGRLSADCLLARLRGEPRADGQID
VGFTLLTGESI

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=331, Percent_Identity=73.7160120845921, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=42.1686746987952, Blast_Score=281, Evalue=3e-77,
Organism=Escherichia coli, GI1790369, Length=310, Percent_Identity=27.741935483871, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787906, Length=270, Percent_Identity=27.4074074074074, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790194, Length=312, Percent_Identity=26.2820512820513, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788474, Length=313, Percent_Identity=24.2811501597444, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789068, Length=299, Percent_Identity=25.0836120401338, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787948, Length=320, Percent_Identity=25, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789202, Length=293, Percent_Identity=22.5255972696246, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787580, Length=322, Percent_Identity=23.6024844720497, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786540, Length=316, Percent_Identity=23.4177215189873, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36419; Mature: 36419

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKRPGLQDVADQVGVTKMTVSRYLRDPDRVSQALQAKIAAALDSLGYIPNRAPDILSN
CCCCCCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ATSRAIGVLLPSLTNQVFAEVLRGIEQVTDANGYQTMLAHYGYSPELEELRLTSLLSYNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCC
DGLILSERHHSPRTLKMIEVAGIPVVEIMDCVSPCLDMAVGFDNFEAARQMTRLIVERGH
CEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
HQVVYFGARQDERTLIKQQGYEQGMRDAGLPAYSVMMADSSNYSAGVELLCQTQREYPGI
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
NGIISTNDDLAIGALFECQRQGITVPDRMAIAGFHGHDFSRVAHPRLASVLTPREEMGRL
CCEEECCCCEEHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHH
SADCLLARLRGEPRADGQIDVGFTLLTGESI
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCC
>Mature Secondary Structure
MKKKRPGLQDVADQVGVTKMTVSRYLRDPDRVSQALQAKIAAALDSLGYIPNRAPDILSN
CCCCCCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ATSRAIGVLLPSLTNQVFAEVLRGIEQVTDANGYQTMLAHYGYSPELEELRLTSLLSYNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCC
DGLILSERHHSPRTLKMIEVAGIPVVEIMDCVSPCLDMAVGFDNFEAARQMTRLIVERGH
CEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
HQVVYFGARQDERTLIKQQGYEQGMRDAGLPAYSVMMADSSNYSAGVELLCQTQREYPGI
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
NGIISTNDDLAIGALFECQRQGITVPDRMAIAGFHGHDFSRVAHPRLASVLTPREEMGRL
CCEEECCCCEEHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHH
SADCLLARLRGEPRADGQIDVGFTLLTGESI
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]