Click here to switch to the map view.

The map label for this gene is tusC

Identifier: 85060266

GI number: 85060266

Start: 3939869

End: 3940228

Strand: Reverse

Name: tusC

Synonym: SG2288

Alternate gene names: 85060266

Gene position: 3940228-3939869 (Counterclockwise)

Preceding gene: 85060267

Following gene: 85060265

Centisome position: 94.46

GC content: 59.72

Gene sequence:

>360_bases
ATGAACCGTATCGCATTTGTTTTCACCCACGGTCCGCACGGCGACGCCGCTGGACGGGAAGGGCTTGACGCGCTGTTGGC
GACCTCGGCATTGGCGGAGGATATCGGTGTCTTTTTTATCGCCGATGGCGTATTGCTGTTGCTGGAGCAGCAGCAGCCGG
CGCAAATCCTGGCGCGGGACTTTGTCGCCACCTTCGGCGTGCTCTCGCTGTATGATGTGGACAGTCTTTATCTCTGCGCC
GAATCGGCGGCGGAGCGCGGTCTGGATGCCGATGCTGGCTGGGTATTGAACGCTGAATGGTTGTCGGCGGCGGACTGGCG
CCAGCGTCTTAGCGCCTATGATACCGTGATGACGTTTTAA

Upstream 100 bases:

>100_bases
AGCGGCGAAAATCTTCAGCCCGGCTTTGAGCTCAGCGGCCTGGGCAGCCTGGTACAGGCGGCGCTCGGCTGCGATCGCTT
TATCCAGTTCTAAGGCTTCC

Downstream 100 bases:

>100_bases
CGCCGGAGGCGCCCATGCTGTATACCCTGAGCCGTTCTCCCTATGCCTGCGATCTGGCGGCGTTGCTGCGTATCGCGCAG
CACGGCGACGACCTGCTGCT

Product: sulfur relay protein TusC

Products: NA

Alternate protein names: tRNA 2-thiouridine synthesizing protein C

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MNRIAFVFTHGPHGDAAGREGLDALLATSALAEDIGVFFIADGVLLLLEQQQPAQILARDFVATFGVLSLYDVDSLYLCA
ESAAERGLDADAGWVLNAEWLSAADWRQRLSAYDTVMTF

Sequences:

>Translated_119_residues
MNRIAFVFTHGPHGDAAGREGLDALLATSALAEDIGVFFIADGVLLLLEQQQPAQILARDFVATFGVLSLYDVDSLYLCA
ESAAERGLDADAGWVLNAEWLSAADWRQRLSAYDTVMTF
>Mature_119_residues
MNRIAFVFTHGPHGDAAGREGLDALLATSALAEDIGVFFIADGVLLLLEQQQPAQILARDFVATFGVLSLYDVDSLYLCA
ESAAERGLDADAGWVLNAEWLSAADWRQRLSAYDTVMTF

Specific function: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions

COG id: COG2923

COG function: function code P; Uncharacterized protein involved in the oxidation of intracellular sulfur

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dsrF/tusC family

Homologues:

Organism=Escherichia coli, GI1789742, Length=119, Percent_Identity=56.3025210084034, Blast_Score=136, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TUSC_SODGM (Q2NQL2)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455968.1
- ProteinModelPortal:   Q2NQL2
- SMR:   Q2NQL2
- STRING:   Q2NQL2
- GeneID:   3866430
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG2288
- NMPDR:   fig|343509.6.peg.4976
- eggNOG:   COG2923
- HOGENOM:   HBG496129
- OMA:   FKVLPLY
- PhylomeDB:   Q2NQL2
- ProtClustDB:   PRK00211
- BioCyc:   SGLO343509:SG2288-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00389
- InterPro:   IPR003787
- InterPro:   IPR017462
- TIGRFAMs:   TIGR03010

Pfam domain/function: PF02635 DrsE

EC number: NA

Molecular weight: Translated: 12910; Mature: 12910

Theoretical pI: Translated: 3.95; Mature: 3.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIAFVFTHGPHGDAAGREGLDALLATSALAEDIGVFFIADGVLLLLEQQQPAQILARD
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCCHHHHHHH
FVATFGVLSLYDVDSLYLCAESAAERGLDADAGWVLNAEWLSAADWRQRLSAYDTVMTF
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRIAFVFTHGPHGDAAGREGLDALLATSALAEDIGVFFIADGVLLLLEQQQPAQILARD
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCCHHHHHHH
FVATFGVLSLYDVDSLYLCAESAAERGLDADAGWVLNAEWLSAADWRQRLSAYDTVMTF
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA