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The map label for this gene is secY

Identifier: 85060236

GI number: 85060236

Start: 3920806

End: 3922137

Strand: Reverse

Name: secY

Synonym: SG2258

Alternate gene names: 85060236

Gene position: 3922137-3920806 (Counterclockwise)

Preceding gene: 85060237

Following gene: 85060235

Centisome position: 94.03

GC content: 50.53

Gene sequence:

>1332_bases
ATGGCTAAACAACCGGGATTAGATTTTCAAAGCGCCAAAGGCGGACTGAGTGAACTGAAACGCAGACTTTTGTTTGTTAT
CGGGGCGCTTATTGTCTTCCGCATAGGCTCTTTTATTCCGATCCCTGGTATTGATGCCACCGTGCTTGCGAAATTGCTCG
AACAGCAGCGGGGCACCATCATTGAAATGTTTAACATGTTCTCTGGTGGTGCGCTCAGCCGTGCTTCTATCTTCGCGTTG
GGGATCATGCCGTATATTTCGGCATCGATAATCATTCAGCTGCTGACGGTGGTTCACCCGGCGCTGGCGGAGATAAAAAA
AGAGGGTGAAGCTGGCAGACGTAAAATCAGCCAGTACACTCGCTATGGCACGTTGGTGTTGGCGATATTTCAGTCAATCG
GTATTGCTACCGGTTTGCCGAATATGCCTGGAATGCAAGGTCTGGTGATTAATCCGGGCTTTGCGTTTTACTTTACTGCG
GTAGTGAGCCTGGTCTGCGGGACGATGTTCCTGATGTGGCTGGGTGAACAGATTACTGAACGGGGTATCGGCAACGGTAT
CTCTATCATTATCTTCGCGGGTATCGTAGCGGGCTTGCCGCCTGCCATCGGCCACACTATTGAGCAAGCTCGACAAGGCG
AAATGCACTTCCTCGTGTTGCTATTGGTTGCAGTTCTGGTGTTTGCGGTAACGTTTTTCGTGGTGTTCGTTGAACGTGGT
CAGCGTCGTATCGTCGTTAACTACGCCAAGCGTCAGCAGGGACGTCGCGTTTATGCAGCCCAGAGCACGCATTTGCCGCT
GAAAGTGAACATGGCTGGGGTTATCCCAGCAATTTTCGCCTCCAGTATCATTCTGTTTCCGGCCACGATCGCATCCTGGT
TCGGAGGTGGCACAGGTTGGGACTGGCTGACTGCGATTTCGCTCTATTTGCAGCCTGGTCAACCGCTTTATGTGTTACTA
TATGCGGCTGCAATCATATTCTTCTGTTTCTTTTACACGGCGTTGGTATTCAACCCGCGCGAGACAGCAGATAACCTGAA
GAAGTCCGGTGCATTTGTACCAGGCATTCGTCCGGGAGAGCAAACGGCAAGGTACATTGATAAGGTGATGACCCGCCTGA
CGTTGGTCGGTGCCATGTACATTACCTTCATCTGCCTAATCCCGGAGTTCATGCGTGACGCAATGAAAGCCCCCTTCTAT
TTTGGGGGCACGTCTTTATTGATCGTCGTTGTGGTTATCATGGACTTTATGGCTCAAGTGCAGACTCTGATGATGTCGAG
TCAATACGAGTCCGCATTGAAGAAAGCAAACCTGAAAGGCTATAACCGCTAA

Upstream 100 bases:

>100_bases
GAAGTCAAACGTGCGGTAACCATACGTGGCCTGCGTGTTAGCAAAGGCGCGCGTGCTGCGATCGAAGCTGCCGGCGGTAA
AATTGAGGAATAAGTAGCAG

Downstream 100 bases:

>100_bases
TTCAGGAAGCTTGAGAAGTTACGGAGAGTAAAAATGAAAGTTCGTGCTTCCGTCAAGAAATTATGTCGTAACTGTAAAAT
CGTTAAGCGTAACGGTGTCG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MAKQPGLDFQSAKGGLSELKRRLLFVIGALIVFRIGSFIPIPGIDATVLAKLLEQQRGTIIEMFNMFSGGALSRASIFAL
GIMPYISASIIIQLLTVVHPALAEIKKEGEAGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
VVSLVCGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIGHTIEQARQGEMHFLVLLLVAVLVFAVTFFVVFVERG
QRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWDWLTAISLYLQPGQPLYVLL
YAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTARYIDKVMTRLTLVGAMYITFICLIPEFMRDAMKAPFY
FGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYNR

Sequences:

>Translated_443_residues
MAKQPGLDFQSAKGGLSELKRRLLFVIGALIVFRIGSFIPIPGIDATVLAKLLEQQRGTIIEMFNMFSGGALSRASIFAL
GIMPYISASIIIQLLTVVHPALAEIKKEGEAGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
VVSLVCGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIGHTIEQARQGEMHFLVLLLVAVLVFAVTFFVVFVERG
QRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWDWLTAISLYLQPGQPLYVLL
YAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTARYIDKVMTRLTLVGAMYITFICLIPEFMRDAMKAPFY
FGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYNR
>Mature_442_residues
AKQPGLDFQSAKGGLSELKRRLLFVIGALIVFRIGSFIPIPGIDATVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALG
IMPYISASIIIQLLTVVHPALAEIKKEGEAGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTAV
VSLVCGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIGHTIEQARQGEMHFLVLLLVAVLVFAVTFFVVFVERGQ
RRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWDWLTAISLYLQPGQPLYVLLY
AAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTARYIDKVMTRLTLVGAMYITFICLIPEFMRDAMKAPFYF
GGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYNR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=443, Percent_Identity=96.6139954853273, Blast_Score=798, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48577; Mature: 48445

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKQPGLDFQSAKGGLSELKRRLLFVIGALIVFRIGSFIPIPGIDATVLAKLLEQQRGTI
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHH
IEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPALAEIKKEGEAGRRKISQYT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
RYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTAVVSLVCGTMFLMWLGEQITE
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIGNGISIIIFAGIVAGLPPAIGHTIEQARQGEMHFLVLLLVAVLVFAVTFFVVFVERG
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGW
CCEEEEEHHHHHCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DWLTAISLYLQPGQPLYVLLYAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCH
QTARYIDKVMTRLTLVGAMYITFICLIPEFMRDAMKAPFYFGGTSLLIVVVVIMDFMAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHH
QTLMMSSQYESALKKANLKGYNR
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]