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The map label for this gene is arsC [H]

Identifier: 85060047

GI number: 85060047

Start: 3573672

End: 3574034

Strand: Reverse

Name: arsC [H]

Synonym: SG2069

Alternate gene names: 85060047

Gene position: 3574034-3573672 (Counterclockwise)

Preceding gene: 85060048

Following gene: 85060046

Centisome position: 85.68

GC content: 55.37

Gene sequence:

>363_bases
ATGGCCTCGATAACGATTTATCACAACCCTGCATGCAGCACGTCGCGCAAAACGCTTGCGTTAATCCGCGATAGCGGCGT
TGAACCGACCGTGATCCTCTATCTCAAGCAGCCCCCCAGCCGGGCGCAGTTGAAAGAGATGCTTAACGCCATGGGATTAA
GCGCACGTGAGCTGTTGCGCGCCAAAGAGGAGCTGTACCGGCAAGAGAGATTGGATGCGGATAATCTCAGCGAAGATGTT
CTTATCGAGGAGATGCTTAAGGTGCCTATCCTGATTAACCGACCCATCGTGGTCTCACCGCTCGGCACCCGGCTCTGCCG
TCCCGCGGAAACCGTGCTGGATATTTTACCCCCGTCGCAATAA

Upstream 100 bases:

>100_bases
AATGAGGACAGTGCAACCGGAACGCGCAGCGGCCACGTTGAACCTGCCCCATACCGGTCAGGTATGACACATAGCGTCCA
CGACATAACAGGAAAGAACT

Downstream 100 bases:

>100_bases
TGGACGTTATTGCCAAAGGGCATTGCCGCCGTCTCGGCAGGGTCCGGATCGGTTGCCATTGCGCGCTGGATAAAAGGCGG
CTGAGTTGGCGATGATGCCT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 120; Mature: 119

Protein sequence:

>120_residues
MASITIYHNPACSTSRKTLALIRDSGVEPTVILYLKQPPSRAQLKEMLNAMGLSARELLRAKEELYRQERLDADNLSEDV
LIEEMLKVPILINRPIVVSPLGTRLCRPAETVLDILPPSQ

Sequences:

>Translated_120_residues
MASITIYHNPACSTSRKTLALIRDSGVEPTVILYLKQPPSRAQLKEMLNAMGLSARELLRAKEELYRQERLDADNLSEDV
LIEEMLKVPILINRPIVVSPLGTRLCRPAETVLDILPPSQ
>Mature_119_residues
ASITIYHNPACSTSRKTLALIRDSGVEPTVILYLKQPPSRAQLKEMLNAMGLSARELLRAKEELYRQERLDADNLSEDVL
IEEMLKVPILINRPIVVSPLGTRLCRPAETVLDILPPSQ

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=120, Percent_Identity=59.1666666666667, Blast_Score=147, Evalue=1e-37,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=49.1228070175439, Blast_Score=110, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 13449; Mature: 13318

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASITIYHNPACSTSRKTLALIRDSGVEPTVILYLKQPPSRAQLKEMLNAMGLSARELLR
CCEEEEEECCCCCCCCHHEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHH
AKEELYRQERLDADNLSEDVLIEEMLKVPILINRPIVVSPLGTRLCRPAETVLDILPPSQ
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEECCCEEECCCCHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure 
ASITIYHNPACSTSRKTLALIRDSGVEPTVILYLKQPPSRAQLKEMLNAMGLSARELLR
CEEEEEECCCCCCCCHHEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHH
AKEELYRQERLDADNLSEDVLIEEMLKVPILINRPIVVSPLGTRLCRPAETVLDILPPSQ
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEECCCEEECCCCHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]