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The map label for this gene is yqfA [H]

Identifier: 85059976

GI number: 85059976

Start: 3453105

End: 3453755

Strand: Reverse

Name: yqfA [H]

Synonym: SG1998

Alternate gene names: 85059976

Gene position: 3453755-3453105 (Counterclockwise)

Preceding gene: 85059978

Following gene: 85059974

Centisome position: 82.8

GC content: 53.92

Gene sequence:

>651_bases
ATGGGAAACAAACCATTAGCCAAAAACTACTCTCTGGCGGAAGAGATAGCCAATAGCGTCAGCCACGGCGTGGGGGTGAT
CTTTGGTATTGTCGGCCTGGTGCTGATGCTTAATCAGTCAGGGGAGGCGGGCGCTAACGCTCCCGCGCTGACCAGCTACA
GTCTTTATGGCGGTAGTATGATTCTGCTCTATCTGGCGTCGACGTTGTATCATGCCATTCCCCATCCGCTGGCCAAACGC
TGGCTGAAGAAGGTGGACCATTGCGCGATTTATCTGTTAATCGCCGGTACCTATACGCCGTTTTTGCTGATATGTCTGGC
CTCGCCGCTGGCCAAATGGCTGATGGTGGTCATCTGGCTGATGGCGGCGGTCGGCATTATGTTCAAACTGGTGTTTGCGC
ATCGCTTTCGCGCCATCTCCATTATTACCTATCTGACTATGGGTTGGCTGTCGCTGGTGGTCATTTATCAACTGGTACAA
CGGTTGCCCGCCGGCGGCGTCGCGCTGCTGGCCGCCGGTGGCGTGATTTACTCGCTGGGGGTGATTTTCTACGTTTGGGA
ACGAATACCGTTCAACCATGCGATATGGCATGGCTTCGTATTGGGGGGAACCGTTTGCCACTTTCTGGCGATTTATCTGT
TTGTCACTTGA

Upstream 100 bases:

>100_bases
TTATTTTCAGAGTACACATGTACACTCAATTGCCTCTAGATTACCCTATACACTGCATGCCCACGGACGAAGATATCTTT
AAGCAGAGGTCAGAAAATTT

Downstream 100 bases:

>100_bases
ACCGCGGTGGTTTGTCGTTATGTCCCATGGACGGAAAGCGGGTCCGATGCCGCGCCTAGAATCCCCGAACGCGGTTTTCA
AGCGACAGCCTGCGGCGGCC

Product: putative hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MGNKPLAKNYSLAEEIANSVSHGVGVIFGIVGLVLMLNQSGEAGANAPALTSYSLYGGSMILLYLASTLYHAIPHPLAKR
WLKKVDHCAIYLLIAGTYTPFLLICLASPLAKWLMVVIWLMAAVGIMFKLVFAHRFRAISIITYLTMGWLSLVVIYQLVQ
RLPAGGVALLAAGGVIYSLGVIFYVWERIPFNHAIWHGFVLGGTVCHFLAIYLFVT

Sequences:

>Translated_216_residues
MGNKPLAKNYSLAEEIANSVSHGVGVIFGIVGLVLMLNQSGEAGANAPALTSYSLYGGSMILLYLASTLYHAIPHPLAKR
WLKKVDHCAIYLLIAGTYTPFLLICLASPLAKWLMVVIWLMAAVGIMFKLVFAHRFRAISIITYLTMGWLSLVVIYQLVQ
RLPAGGVALLAAGGVIYSLGVIFYVWERIPFNHAIWHGFVLGGTVCHFLAIYLFVT
>Mature_215_residues
GNKPLAKNYSLAEEIANSVSHGVGVIFGIVGLVLMLNQSGEAGANAPALTSYSLYGGSMILLYLASTLYHAIPHPLAKRW
LKKVDHCAIYLLIAGTYTPFLLICLASPLAKWLMVVIWLMAAVGIMFKLVFAHRFRAISIITYLTMGWLSLVVIYQLVQR
LPAGGVALLAAGGVIYSLGVIFYVWERIPFNHAIWHGFVLGGTVCHFLAIYLFVT

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI52630445, Length=210, Percent_Identity=32.3809523809524, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI154759275, Length=221, Percent_Identity=31.2217194570136, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI154759277, Length=245, Percent_Identity=28.1632653061224, Blast_Score=85, Evalue=5e-17,
Organism=Escherichia coli, GI1789266, Length=216, Percent_Identity=73.1481481481482, Blast_Score=317, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI71996356, Length=214, Percent_Identity=33.1775700934579, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24640324, Length=226, Percent_Identity=30.5309734513274, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 23614; Mature: 23483

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNKPLAKNYSLAEEIANSVSHGVGVIFGIVGLVLMLNQSGEAGANAPALTSYSLYGGSM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCHHH
ILLYLASTLYHAIPHPLAKRWLKKVDHCAIYLLIAGTYTPFLLICLASPLAKWLMVVIWL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAAVGIMFKLVFAHRFRAISIITYLTMGWLSLVVIYQLVQRLPAGGVALLAAGGVIYSLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VIFYVWERIPFNHAIWHGFVLGGTVCHFLAIYLFVT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GNKPLAKNYSLAEEIANSVSHGVGVIFGIVGLVLMLNQSGEAGANAPALTSYSLYGGSM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCHHH
ILLYLASTLYHAIPHPLAKRWLKKVDHCAIYLLIAGTYTPFLLICLASPLAKWLMVVIWL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAAVGIMFKLVFAHRFRAISIITYLTMGWLSLVVIYQLVQRLPAGGVALLAAGGVIYSLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VIFYVWERIPFNHAIWHGFVLGGTVCHFLAIYLFVT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]