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The map label for this gene is pcp2 [H]

Identifier: 85059826

GI number: 85059826

Start: 3139638

End: 3140216

Strand: Reverse

Name: pcp2 [H]

Synonym: SG1848

Alternate gene names: 85059826

Gene position: 3140216-3139638 (Counterclockwise)

Preceding gene: 85059830

Following gene: 85059825

Centisome position: 75.28

GC content: 59.93

Gene sequence:

>579_bases
ATGTCAGTTGTACTTGTAACCGGTATCGAACTTTTTGATGGTGAAAGCCTGAACCCTTCCTGGGAAGTCGCGCGCAGGCT
GGATGGAGAACAGGTGGATGGAGCGACGCTGGTGGCGCGCCAACTGCCGTGCGTAATCGGGCGGGTTAACCCGGCGTTGT
TTCAAATGCTGACGGCGCTGCGTTCGTCGCTGGTCCTTTGCCTCGGTCAGGCCGGCGGCCGTGTCGATATCACGTTGGAG
CGGGTGGCGATTAATATTGTCGACGCGCGTATTCCCGATAACGCCGGCCAGCAGCCGGTGGATGAACCGATTTTCCCGCA
GAGACCCGCCGGCTATTTTTCCACGTTGCCCATCAAGGCCATGGTGCGGGCGCTGCGCCGACAGGGGATCCCCGCCTCTG
TTTCCCAGACCGCCGGTACCTGTAATTGTAACGCGATTTTTTACGGTCTTTGCCACTATATCGCCAGCCGGCAACCCCCA
TGCGCGGCGGATTTGTCCATTTACCCTATTTGCCGGAGATGGCGGCGGCGCATCCCGGTGCGCCCAGTATGGCGTTGGCG
ACCCAACTTGACGCCGTAA

Upstream 100 bases:

>100_bases
ATTCATAAAATCAATATTAGAAATATTGTTTATCCATTTCAAGAATTGTTTGTTCTCCGGCTATCATGCTGCGATAACGC
GAGGTGATAGGAGAGGCGCC

Downstream 100 bases:

>100_bases
AGACGTTAATCCGCACCGCCTTAACCACTACCAGCTATATTCGCGTGGGGCCGGCGCGCTGCATTGACGTGGGAAATAGG
GCGAAACCCCCTCTTCACCG

Product: putative pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase 2; Pyroglutamyl-peptidase I 2; PGP-I 2; Pyrase 2 [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MSVVLVTGIELFDGESLNPSWEVARRLDGEQVDGATLVARQLPCVIGRVNPALFQMLTALRSSLVLCLGQAGGRVDITLE
RVAINIVDARIPDNAGQQPVDEPIFPQRPAGYFSTLPIKAMVRALRRQGIPASVSQTAGTCNCNAIFYGLCHYIASRQPP
CAADLSIYPICRRWRRRIPVRPVWRWRPNLTP

Sequences:

>Translated_192_residues
MSVVLVTGIELFDGESLNPSWEVARRLDGEQVDGATLVARQLPCVIGRVNPALFQMLTALRSSLVLCLGQAGGRVDITLE
RVAINIVDARIPDNAGQQPVDEPIFPQRPAGYFSTLPIKAMVRALRRQGIPASVSQTAGTCNCNAIFYGLCHYIASRQPP
CAADLSIYPICRRWRRRIPVRPVWRWRPNLTP
>Mature_191_residues
SVVLVTGIELFDGESLNPSWEVARRLDGEQVDGATLVARQLPCVIGRVNPALFQMLTALRSSLVLCLGQAGGRVDITLER
VAINIVDARIPDNAGQQPVDEPIFPQRPAGYFSTLPIKAMVRALRRQGIPASVSQTAGTCNCNAIFYGLCHYIASRQPPC
AADLSIYPICRRWRRRIPVRPVWRWRPNLTP

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 21246; Mature: 21115

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS01333 PYRASE_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVLVTGIELFDGESLNPSWEVARRLDGEQVDGATLVARQLPCVIGRVNPALFQMLTAL
CEEEEEECEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHCCHHHHCCCHHHHHHHHHH
RSSLVLCLGQAGGRVDITLERVAINIVDARIPDNAGQQPVDEPIFPQRPAGYFSTLPIKA
HHHHHHHHCCCCCEEEEEEEHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHH
MVRALRRQGIPASVSQTAGTCNCNAIFYGLCHYIASRQPPCAADLSIYPICRRWRRRIPV
HHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
RPVWRWRPNLTP
CCEECCCCCCCC
>Mature Secondary Structure 
SVVLVTGIELFDGESLNPSWEVARRLDGEQVDGATLVARQLPCVIGRVNPALFQMLTAL
EEEEEECEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHCCHHHHCCCHHHHHHHHHH
RSSLVLCLGQAGGRVDITLERVAINIVDARIPDNAGQQPVDEPIFPQRPAGYFSTLPIKA
HHHHHHHHCCCCCEEEEEEEHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHH
MVRALRRQGIPASVSQTAGTCNCNAIFYGLCHYIASRQPPCAADLSIYPICRRWRRRIPV
HHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
RPVWRWRPNLTP
CCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]