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The map label for this gene is arnB

Identifier: 85059823

GI number: 85059823

Start: 3130565

End: 3131704

Strand: Reverse

Name: arnB

Synonym: SG1845

Alternate gene names: 85059823

Gene position: 3131704-3130565 (Counterclockwise)

Preceding gene: 85059824

Following gene: 85059822

Centisome position: 75.08

GC content: 62.11

Gene sequence:

>1140_bases
ATGTCTGAATTTTTGCCGTTCTCCCGGCCTGCGCTGGGCGACGCCGAGCTTGCCGCCGTCGGGGACGTGCTGCGGTCCGG
CTGGATCACCACCGGGCCGAAATGCGCGCAGCTGGAGCAGGCTTTTTGTCAATTGACCGGCAATCGACATGCCATTGCCG
TGAGCTCTGCGACCGGCGGTATGCACGTGACGCTCATGGCCTTGGGGCTAGGGCCGGGCGACGAGGTGATTACTCCTTCG
CTAACCTGGGTTTCCACCCTGAACATGATCTGTCTGCTTGGCGCCGAACCCATCATGATTGATGTCGACCGTGACACGCT
GATGGTGACGCCGGCGTTGATTGAAGCGGCGATCACACCGCGTACCCGCGCGATTGTACCGGTACATTACGCCGGCGCGC
CGGCGGACATCGACGCCATTCGTGCGCTGGGCGAACGCTACGGTATTCCGGTGATTGAGGATGCGGCGCATGCAGCGGGA
ACCGCTTACAAAGGTCGTCACGTGGGCGCCGCCGGCACCGCCATTTTCTCGTTCCACGCCATCAAGAATATGACCTGCGC
CGAAGGGGGGATGGTGGTGACGGATGACGATGCGCTGGCGCAGCGTATCCGCAGCCTGAAGTTTCACGGCCTGGCGGTGG
ATGCGTTCGATCGCACCATGCAGGGCAGGGCCCCGCAGGCGGAAGTGATTACGCCGGGCTACAAATATAATCTGGCCGAT
ATCAATGCCGCCATCGCTCTGGTGCAGCTCGAAAAACTGACGCAGCACAATGCGCGCCGGGCGGCGCTTGCCCAGCGCTA
TTTGCACGGCCTGGCAGACACGCCGTTTTTGCCGCTGGTGCCGCCAGCCTGGGAACACCACCACGCCTGGCACCTGTTTA
TCATCCGCGTCGACGAGCGGTGGTGCGGTATCGATCGCGACGGCCTGATGCAGGCGCTGAAAGAATGCGGTATCGGCACC
GGCCTCCATTTTCGCGCCGCCCATACGCAGCGTTACTACCGCGAGCGTTTTCCCGATATGGTCTTGCCGGCCACCGAGTG
GAACTCCGTGCGTATGTGTTCACTGCCGCTTTTCCCCTCCATGAACGATGACGATGTCGAGCGTGTGATTACCGCGCTGC
GCGCCATTGCCAAGGTTTGA

Upstream 100 bases:

>100_bases
CATTACAGAACTTTACCGTTCGGCGGAAATACAGCTCACGCCAATTATGCTGCTTGCTGCTGCTCGATCTTGGCTCGCCA
TTTTTAAGGGAAATCAAATA

Downstream 100 bases:

>100_bases
TATGACGACACCCATGAAAATTGACAAAGTTTCGATCGTAATTCCGGTCTATAACGAGCAAGAAAGCCTGCCAGAGCTGA
TGCGCCGCACGGTGGCGGCC

Product: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase

Products: NA

Alternate protein names: UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase; UDP-Ara4O aminotransferase; UDP-4-amino-4-deoxy-L-arabinose aminotransferase

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSEFLPFSRPALGDAELAAVGDVLRSGWITTGPKCAQLEQAFCQLTGNRHAIAVSSATGGMHVTLMALGLGPGDEVITPS
LTWVSTLNMICLLGAEPIMIDVDRDTLMVTPALIEAAITPRTRAIVPVHYAGAPADIDAIRALGERYGIPVIEDAAHAAG
TAYKGRHVGAAGTAIFSFHAIKNMTCAEGGMVVTDDDALAQRIRSLKFHGLAVDAFDRTMQGRAPQAEVITPGYKYNLAD
INAAIALVQLEKLTQHNARRAALAQRYLHGLADTPFLPLVPPAWEHHHAWHLFIIRVDERWCGIDRDGLMQALKECGIGT
GLHFRAAHTQRYYRERFPDMVLPATEWNSVRMCSLPLFPSMNDDDVERVITALRAIAKV

Sequences:

>Translated_379_residues
MSEFLPFSRPALGDAELAAVGDVLRSGWITTGPKCAQLEQAFCQLTGNRHAIAVSSATGGMHVTLMALGLGPGDEVITPS
LTWVSTLNMICLLGAEPIMIDVDRDTLMVTPALIEAAITPRTRAIVPVHYAGAPADIDAIRALGERYGIPVIEDAAHAAG
TAYKGRHVGAAGTAIFSFHAIKNMTCAEGGMVVTDDDALAQRIRSLKFHGLAVDAFDRTMQGRAPQAEVITPGYKYNLAD
INAAIALVQLEKLTQHNARRAALAQRYLHGLADTPFLPLVPPAWEHHHAWHLFIIRVDERWCGIDRDGLMQALKECGIGT
GLHFRAAHTQRYYRERFPDMVLPATEWNSVRMCSLPLFPSMNDDDVERVITALRAIAKV
>Mature_378_residues
SEFLPFSRPALGDAELAAVGDVLRSGWITTGPKCAQLEQAFCQLTGNRHAIAVSSATGGMHVTLMALGLGPGDEVITPSL
TWVSTLNMICLLGAEPIMIDVDRDTLMVTPALIEAAITPRTRAIVPVHYAGAPADIDAIRALGERYGIPVIEDAAHAAGT
AYKGRHVGAAGTAIFSFHAIKNMTCAEGGMVVTDDDALAQRIRSLKFHGLAVDAFDRTMQGRAPQAEVITPGYKYNLADI
NAAIALVQLEKLTQHNARRAALAQRYLHGLADTPFLPLVPPAWEHHHAWHLFIIRVDERWCGIDRDGLMQALKECGIGTG
LHFRAAHTQRYYRERFPDMVLPATEWNSVRMCSLPLFPSMNDDDVERVITALRAIAKV

Specific function: Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family. ArnB subfamily

Homologues:

Organism=Escherichia coli, GI145693159, Length=377, Percent_Identity=76.1273209549072, Blast_Score=586, Evalue=1e-168,
Organism=Escherichia coli, GI2367285, Length=396, Percent_Identity=33.0808080808081, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARNB_SODGM (Q2NRV5)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455525.1
- HSSP:   Q8ZNF3
- ProteinModelPortal:   Q2NRV5
- SMR:   Q2NRV5
- STRING:   Q2NRV5
- GeneID:   3868638
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1845
- NMPDR:   fig|343509.6.peg.3899
- eggNOG:   COG0399
- HOGENOM:   HBG660897
- OMA:   SEWNSAR
- PhylomeDB:   Q2NRV5
- ProtClustDB:   PRK11658
- BioCyc:   SGLO343509:SG1845-MONOMER
- HAMAP:   MF_01167
- InterPro:   IPR022850
- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000390

Pfam domain/function: PF01041 DegT_DnrJ_EryC1; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.87

Molecular weight: Translated: 41228; Mature: 41097

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFLPFSRPALGDAELAAVGDVLRSGWITTGPKCAQLEQAFCQLTGNRHAIAVSSATGG
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCC
MHVTLMALGLGPGDEVITPSLTWVSTLNMICLLGAEPIMIDVDRDTLMVTPALIEAAITP
EEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEECHHHHHHHCCC
RTRAIVPVHYAGAPADIDAIRALGERYGIPVIEDAAHAAGTAYKGRHVGAAGTAIFSFHA
CCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHH
IKNMTCAEGGMVVTDDDALAQRIRSLKFHGLAVDAFDRTMQGRAPQAEVITPGYKYNLAD
HCCCEECCCCEEEECCHHHHHHHHHHHHCCEEEHHHHHHHCCCCCCCCEECCCCEEEHHH
INAAIALVQLEKLTQHNARRAALAQRYLHGLADTPFLPLVPPAWEHHHAWHLFIIRVDER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCH
WCGIDRDGLMQALKECGIGTGLHFRAAHTQRYYRERFPDMVLPATEWNSVRMCSLPLFPS
HCCCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCC
MNDDDVERVITALRAIAKV
CCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEFLPFSRPALGDAELAAVGDVLRSGWITTGPKCAQLEQAFCQLTGNRHAIAVSSATGG
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCC
MHVTLMALGLGPGDEVITPSLTWVSTLNMICLLGAEPIMIDVDRDTLMVTPALIEAAITP
EEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEECHHHHHHHCCC
RTRAIVPVHYAGAPADIDAIRALGERYGIPVIEDAAHAAGTAYKGRHVGAAGTAIFSFHA
CCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHH
IKNMTCAEGGMVVTDDDALAQRIRSLKFHGLAVDAFDRTMQGRAPQAEVITPGYKYNLAD
HCCCEECCCCEEEECCHHHHHHHHHHHHCCEEEHHHHHHHCCCCCCCCEECCCCEEEHHH
INAAIALVQLEKLTQHNARRAALAQRYLHGLADTPFLPLVPPAWEHHHAWHLFIIRVDER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCH
WCGIDRDGLMQALKECGIGTGLHFRAAHTQRYYRERFPDMVLPATEWNSVRMCSLPLFPS
HCCCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCC
MNDDDVERVITALRAIAKV
CCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA