Click here to switch to the map view.

The map label for this gene is arnC

Identifier: 85059822

GI number: 85059822

Start: 3129583

End: 3130563

Strand: Reverse

Name: arnC

Synonym: SG1844

Alternate gene names: 85059822

Gene position: 3130563-3129583 (Counterclockwise)

Preceding gene: 85059823

Following gene: 85059821

Centisome position: 75.05

GC content: 56.68

Gene sequence:

>981_bases
ATGACGACACCCATGAAAATTGACAAAGTTTCGATCGTAATTCCGGTCTATAACGAGCAAGAAAGCCTGCCAGAGCTGAT
GCGCCGCACGGTGGCGGCCTGTGAACAGCTCGACGCCGCCTATGAAATCTTGCTGGTGGATGATGGCAGCAGCGACGATT
CCGCCGCCGTGCTGACCGCCGCGGCGGAAGCGCCGGGCAGCCATATCGTCGCGGTATTGCTCAACCGCAATTATGGTCAG
CACTCCGCCATCATGGCGGGGTTCAGCCATGTTACCGGCGACCTGGTGGTGACGCTCGATGCGGATTTGCAGAATCCGCC
GGAAGAGATCCCGCGGCTGGTCGAGGTGGCGGCGCAGGATTACGACGTGGTGGGCACCGTGCGCCAGAATCGGCAGGACA
GCTGGTTCCGCAAGCGTGCCTCACGCATGATTAACGCGTTGATCCAGCGTACGACCGGCAAAGCGATGGGTGATTACGGC
TGCATGTTGCGCGCCTACCGCCGCCACATTATCGACGCCATGCTGCACTGCCACGAGCGCAGCACGTTCATACCGATTCT
GGCCAATACCTTTGCCCGCAAAACCATCGAAATACCGGTAATGCATTCGGAAAGGGAGTTTGGCGATTCCAAATACAGTC
TGATGAAGCTCGTCAATCTGATGTACGACCTCGTCACCTGTCTGACGACCACGCCGCTGCGCATGCTGAGCGTTATCGGC
AGCATGATTGCCCTGCTGGGGTTTGCCTTTTCCCTACTGCTCATCACGTTGCGCCTGTTTCTCGGCTCCCATTGGGCGGC
TGAAGGTGTCTTTATGCTGTTTGCGGTGCTGTTTATTTTTATCGGCGCGCAATTCATCGGCATGGGGCTATTGGGAGAAT
ATATCGGCCGTATCTACAACGATGTGCGTGCCCGTCCCCGTTATTTCGTCCAGTGTGTGGTCAGTCAAAATCCACTCTCG
TCTCAACAGGAAACACAATGA

Upstream 100 bases:

>100_bases
AACTCCGTGCGTATGTGTTCACTGCCGCTTTTCCCCTCCATGAACGATGACGATGTCGAGCGTGTGATTACCGCGCTGCG
CGCCATTGCCAAGGTTTGAT

Downstream 100 bases:

>100_bases
AAGCTGTCATTTTTGCTTATCATGATATGGGCTGCGTGGGCGTCACCGCCCTTATCAACGCAGGCTATACTATCGAGGCC
ATCATTACCCATCCTGATGC

Product: undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTTPMKIDKVSIVIPVYNEQESLPELMRRTVAACEQLDAAYEILLVDDGSSDDSAAVLTAAAEAPGSHIVAVLLNRNYGQ
HSAIMAGFSHVTGDLVVTLDADLQNPPEEIPRLVEVAAQDYDVVGTVRQNRQDSWFRKRASRMINALIQRTTGKAMGDYG
CMLRAYRRHIIDAMLHCHERSTFIPILANTFARKTIEIPVMHSEREFGDSKYSLMKLVNLMYDLVTCLTTTPLRMLSVIG
SMIALLGFAFSLLLITLRLFLGSHWAAEGVFMLFAVLFIFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQCVVSQNPLS
SQQETQ

Sequences:

>Translated_326_residues
MTTPMKIDKVSIVIPVYNEQESLPELMRRTVAACEQLDAAYEILLVDDGSSDDSAAVLTAAAEAPGSHIVAVLLNRNYGQ
HSAIMAGFSHVTGDLVVTLDADLQNPPEEIPRLVEVAAQDYDVVGTVRQNRQDSWFRKRASRMINALIQRTTGKAMGDYG
CMLRAYRRHIIDAMLHCHERSTFIPILANTFARKTIEIPVMHSEREFGDSKYSLMKLVNLMYDLVTCLTTTPLRMLSVIG
SMIALLGFAFSLLLITLRLFLGSHWAAEGVFMLFAVLFIFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQCVVSQNPLS
SQQETQ
>Mature_325_residues
TTPMKIDKVSIVIPVYNEQESLPELMRRTVAACEQLDAAYEILLVDDGSSDDSAAVLTAAAEAPGSHIVAVLLNRNYGQH
SAIMAGFSHVTGDLVVTLDADLQNPPEEIPRLVEVAAQDYDVVGTVRQNRQDSWFRKRASRMINALIQRTTGKAMGDYGC
MLRAYRRHIIDAMLHCHERSTFIPILANTFARKTIEIPVMHSEREFGDSKYSLMKLVNLMYDLVTCLTTTPLRMLSVIGS
MIALLGFAFSLLLITLRLFLGSHWAAEGVFMLFAVLFIFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQCVVSQNPLSS
QQETQ

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family

Homologues:

Organism=Homo sapiens, GI4503363, Length=236, Percent_Identity=27.5423728813559, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1788588, Length=318, Percent_Identity=78.6163522012579, Blast_Score=533, Evalue=1e-153,
Organism=Escherichia coli, GI1788692, Length=315, Percent_Identity=31.7460317460317, Blast_Score=169, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71999402, Length=236, Percent_Identity=25, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325441, Length=106, Percent_Identity=33.0188679245283, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24585265, Length=240, Percent_Identity=27.5, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARNC_SODGM (Q2NRV6)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455524.1
- ProteinModelPortal:   Q2NRV6
- SMR:   Q2NRV6
- STRING:   Q2NRV6
- GeneID:   3868637
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1844
- NMPDR:   fig|343509.6.peg.3898
- eggNOG:   COG0463
- HOGENOM:   HBG752660
- OMA:   MKDYGCM
- PhylomeDB:   Q2NRV6
- ProtClustDB:   PRK10714
- BioCyc:   SGLO343509:SG1844-MONOMER
- HAMAP:   MF_01164
- InterPro:   IPR022857
- InterPro:   IPR001173

Pfam domain/function: PF00535 Glycos_transf_2

EC number: =2.7.8.30

Molecular weight: Translated: 36402; Mature: 36271

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfe0aa20)-; HASH(0xfc90fcc)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPMKIDKVSIVIPVYNEQESLPELMRRTVAACEQLDAAYEILLVDDGSSDDSAAVLTA
CCCCCEECEEEEEEEECCCHHHHHHHHHHHHHHHHHHCHHEEEEEEECCCCCCCHHEEEE
AAEAPGSHIVAVLLNRNYGQHSAIMAGFSHVTGDLVVTLDADLQNPPEEIPRLVEVAAQD
CCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
YDVVGTVRQNRQDSWFRKRASRMINALIQRTTGKAMGDYGCMLRAYRRHIIDAMLHCHER
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
STFIPILANTFARKTIEIPVMHSEREFGDSKYSLMKLVNLMYDLVTCLTTTPLRMLSVIG
CCHHHHHHHHHHHHEEEEEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMIALLGFAFSLLLITLRLFLGSHWAAEGVFMLFAVLFIFIGAQFIGMGLLGEYIGRIYN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRARPRYFVQCVVSQNPLSSQQETQ
HHHCCHHHHHHHHCCCCCCCCCCCCH
>Mature Secondary Structure 
TTPMKIDKVSIVIPVYNEQESLPELMRRTVAACEQLDAAYEILLVDDGSSDDSAAVLTA
CCCCEECEEEEEEEECCCHHHHHHHHHHHHHHHHHHCHHEEEEEEECCCCCCCHHEEEE
AAEAPGSHIVAVLLNRNYGQHSAIMAGFSHVTGDLVVTLDADLQNPPEEIPRLVEVAAQD
CCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
YDVVGTVRQNRQDSWFRKRASRMINALIQRTTGKAMGDYGCMLRAYRRHIIDAMLHCHER
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
STFIPILANTFARKTIEIPVMHSEREFGDSKYSLMKLVNLMYDLVTCLTTTPLRMLSVIG
CCHHHHHHHHHHHHEEEEEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMIALLGFAFSLLLITLRLFLGSHWAAEGVFMLFAVLFIFIGAQFIGMGLLGEYIGRIYN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRARPRYFVQCVVSQNPLSSQQETQ
HHHCCHHHHHHHHCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA